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Appendicitis {A Disorder of Digestive System} Contents • • • • • • • • Appendix Functions Introduction of Appendicitis. Symptoms. Causes. Pathophysiology Treatment. Complications. What is Appendix? • The appendix is small, tube like structure attached to first part of large intestine. • The appendix is a small pouch, normally about 5 to 10 cm long (2 to 4 ins) and quite thin Functions • The appendix has no known function in humans. • Evidence suggests that our evolutionary ancestors used their appendixes to digest tough food like tree bark, but we don't use ours in digestion now. • Whether the appendix has a function or not, it can be removed without any ill effects. What is Appendicitis? • It refers to the condition characterized by inflammation of the appendix. • If untreated, mortality is high, mainly because of the risk of rupture leading to infection and inflammation of the intestinal lining (peritoneum) • If the blockage is not treated, the appendix can burst and spread infection into the abdomen. This causes a condition called peritonitis. • Appendicitis is a medical emergency. Treatment almost always involves removing the appendix. Anyone can get appendicitis, but it is more common among people between 10 to 30 years old. Symptoms • The main symptom is pain in the abdomen. , often on the right side. • Swelling in the abdomen. • • • • • • Loss of appetite Nausea and vomiting Constipation or diarrhea Inability to pass gas Low fever Not everyone with appendicitis has all these symptoms. Causes • An obstruction. Food waste or a hard piece of stool (fecal stone) can block the opening of the cavity that runs the length of your appendix. • An infection. Appendicitis may also follow an infection, such as a gastrointestinal viral infection, or it may result from other types of inflammation. • In both cases, bacteria inside the appendix multiply rapidly, causing the appendix to become inflamed, swollen and filled with pus. If not treated promptly, the appendix can rupture. Pathophysiology • Appendix become obstructed • Increase intra-luminal pressure • Decrease venous drainage, Thrombosis, Edema, and Bacterial Invasion of Bowel Wall. • Appendix become increasingly hyperemic, warm and covered with exudate. • Perforation and gangrene of appendix Treatment & Management Medical examination: The original test for appendicitis, a simple examination of the belly remains important in making the diagnosis. Changes in the abdominal exam help doctors tell if appendicitis is progressing, as well. CT scan (computed tomography): A CT scanner uses X-rays and a computer to create detailed images. In appendicitis, CT scans can show the inflamed appendix, and whether it has ruptured. Ultrasound: An ultrasound uses sound waves to detect signs of appendicitis, such as a swollen appendix. Complete blood count (CBC): An increased number of white blood cells -- a sign of infection and inflammation -- are often seen on blood tests during appendicitis. • Surgery to remove the appendix, which is called an appendectomy, is the standard treatment for appendicitis. Complications.. • If your appendix bursts, it releases pus to other parts of the body, which can cause an infection in the abdomen called peritonitis. • Peritonitis is the painful swelling of the abdomen area around the stomach and liver. The condition causes your normal bowel movements to stop and your bowel to become blocked. • This causes: • severe abdominal pain • a fever of 38ºC (100.4ºF) or more • a rapid heartbeat • If peritonitis is not treated immediately it can cause long-term problems and may even be fatal Preventing Appendicitis • Studies have shown that the incidence of appendicitis is a lot lower in countries where a high-fiber diet is common. • It is not known exactly why this is, but one possible reason is that fiber makes our stools softer, reducing the chances of them getting stuck in the appendix. • Foods high in fiber include: – – – wholegrain cereals, bread, rice. vegetables, such as carrots fruits