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AP Biology 12 Concept 1 continued: Analyzing components & reproduction cycles of viruses You must know: o o The components of a virus The differences between lytic and lysogenic cycles How were viruses first discovered? How big are viruses? What is a virus made of? Genetic material: single or double stranded _______ or single or double stranded _______ Protein shell: __________________ Some viruses also have ____________________from membrane of host cells Try This! 1. Which of the following is not a property of life shared by prokaryotic cells, eukaryotic cells, and viruses? A. nucleic acids used to store hereditary information B. order and complexity in arrangement of biological molecules C. D. the ability to process energy through metabolic reactions the capacity to evolve 2. Classify each statement as TRUE or FALSE, and identify which statement supports the view of most biologists that viruses are nonliving. A. Viruses are two-dimensional, rather than three-dimensional. B. The viral genome may be single- or double-stranded. C. Viruses are obligate intracellular parasites. D. An isolated virus is unable to replicate its genes or regenerate ATP. 3. Bacteriophages were grown in a medium containing radioactive sulfur (35S) and radioactive phosphorous (32P), which are incorporated into proteins and DNA, respectively. If these phages were used to infect a bacterial culture, which isotope would be detected within the infected bacteria? A. 35 B. 32 C. D. both neither S P How do viruses replicate? The Lytic Cycle Ends in ________________of host cell by rupturing (lysis) Bacteriophage injects its DNA into host and takes over ______________________of host to synthesis new copies of virus (DNA and protein coats) They self-assemble and then release. Lysogenic Cycle Bacteriophage DNA becomes incorporated into the ____________cell’s DNA and is replicated along with the host cell’s genetic information Viral DNA is called ______________________ Sometimes, prophage will enter the lytic cycle. Retroviruses Use the enzyme reverse transcriptase Example: ____________________ Try This! 4. AZT is a nucleoside analog used to treat HIV infections. It is a thymine (T) nucleotide with an azide group instead of the hydroxyl group found in typical thymine nucleosides. Which step does AZT hamper in the reproductive cycle of the HIV virus? A. entry into the cell B. reverse transcription of DNA from RNA C. D. transcription of RNA from proviral DNA viral assembly within the cell Viroids and Prions: the really little guys Viroids – circular RNA o Mostly affects __________________ Prions –__________________, infectious protein o Example: Mad Cow Try This! 5. Identify all correct statements. A. Unlike viruses, viroids do not encode proteins. B. Unlike viruses, the genetic material of a viroid is RNA. C. D. Unlike viruses, prions are infectious proteins. Unlike viruses, prions do not include any nucleic acids. Can you do these? 1. Explain how capsids and envelopes are formed 2. Distinguish between the lytic and lysogenic reproductive cycles 3. Explain why viruses are obligate intracellular parasites 4. Describe the reproductive cycle of an HIV retrovirus 5. Describe three processes that lead to the emergence of new diseases 6. Describe viroids and prions