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#1 Free Legal Website FindLaw.com is the leading and largest online resource for legal information. For basic legal issues to more complex ones, you’ll find thousands of helpful articles, a legal community to get answers to your specific questions, an attorney directory, blogs, news, DIY forms, and much more. Fen-Phen FAQ Q: What is "Fen-phen"? A: "Fen-phen" refers to the use in combination of the drugs fenfluramine and phentermine, and phentermine and dexfenfluramine (also called "dexfen-phen"). In the 1990’s, some physicians began prescribing fenfluramine or dexfenfluramine in combination with phentermine, often for extended periods of time, for use in weight loss programs. Q: Did Fen-phen Receive FDA Approval? A: While the prescription medications fenfluramine, phentermine, and dexfenfluramine received individual approval by the U.S. Food and Drug Administration (FDA), use of the drugs in combination never received FDA approval. Use of approved drugs in ways other than described in the FDA-approved label is called "off-label use." In the case of fen-phen and dexfenphen, no studies were presented to the FDA to demonstrate either the effectiveness or safety of the drugs taken in combination. Q: Why Was Fen-phen Withdrawn from the Market? A: In September 1997, the FDA asked the manufacturers to voluntarily withdraw dexfenfluramine and fenfluramine from the market. The FDA’s withdrawal request came after echocardiogram testing of fen-phen patients suggested that fenfluramine and dexfenfluramine were the likely cause of heart valve problems. FDA recommended that patients using either of these products stop taking them, and advised patients to contact their doctors to discuss their treatment. Q: What are the Heart Risks for Fen-Phen Users? A: Patients who have taken fenfluramine and dexfenfluramine may have changes in their heart valves that cause leakiness and backflow of blood. If this is severe, the heart has to work harder. This may cause problems in heart function. If the disease is severe, the patient may experience such symptoms as shortness of breath, excessive tiredness, chest pain, fainting, and swelling of the legs (edema). Q: With the Removal of Fen-phen from the Market, What Should Overweight Persons Do If They Want to Improve Their Health? A: The FDA and Centers for Disease Control and Prevention (CDC) recommend that persons who are less than 20% overweight begin a life-long program of moderate physical exercise -- such as brisk walking for 30 to 45 minutes -- on most days of the week. Regular moderate physical activity is likely to improve weight control and will also strengthen the hear t. Overweight persons should also begin to make moderate and life-long changes in their food choices and eating practices, including reducing the total amount of calories they eat and ensuring that their diet is low in saturated fat and rich in fruits and vegetables. Persons who have a significant weight problem are advised to consult their physician to develop a strategy that is individualized for them. There are a number of options available that a physician can discuss with the patient. Q: Have Their Been Any Lawsuits Filed Over Fen-Phen? A: Since fenfluramine and dexfenfluramine were pulled from the market, hundreds of former fen-phen patients have filed lawsuits against the drugs’ manufacturers, including a nationwide class action suit that was settled and received judicial approval in January 2002. If you or a loved one have suffered illness or injury as a result of fen-phen drug use, your rights may be impacted by the nationwide class action or by other legal proceedings related to fen-phen. But you may still be entitled to file a lawsuit for any harm caused by fen-phen drug use, especially if your health problems or risks were discovered only recently. The best way to ensure that your legal rights are protected is to contact an attorney , who will consider your case and explain your options. The FindLaw Guide to Online Fraud and Identity Theft FINDLAW.COM EMPOWERS PEOPLE WITH TRUSTED, TIMELY AND INTELLIGENT LEGAL INFORMATION BLOGS – FindLaw Blogs present timely news that has real-life implications, deliver important information and discuss law-related entertainment. FINDLAW ANSWERS – A vibrant, interactive online community where everyday people can ask legal questions and get real-time answers from legal professionals and others with similar experiences. 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Some of the social key channels are the following: • FindLaw for Consumers on Facebook Making the law easy to access with interactive legal updates aimed at starting conversations, informing followers of their legal rights and providing a forum for questions and resources • HAVE A LEGAL QUESTION? NEED TO FIND AN AFFORDABLE, QUALIFIED ATTORNEY? Protect yourself, your family or your business with a legal plan or form from LegalStreet @FindLawConsumer on Twitter Tweeting interesting, entertaining and informative legal news everyday Copyright © 2013 FindLaw, a Thomson Reuters business. All rights reserved. The information contained in this article is for informational purposes only and does not constitute legal advice. The use and distribution of this article is subject to the Creative Commons BY-NC-ND license, which Learn More: Tips to Help Protect Your Identity, Protect Find a Consumer Protection can be viewed at http://creativecommons.org/licenses/by-nc-nd/3.0/. 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