Download 2015 UPDATE FOR COHG GLOBAL ALLIANCE PARTNERS NIHR

2015 UPDATE FOR COHG GLOBAL ALLIANCE PARTNERS
NIHR and the Global Alliance have made the Cochrane Oral Health Group
a world leader in evidence-based oral health care.
THANKS TO YOUR SUPPORT OVER THE PAST 4 YEARS, WE HAVE:
PUBLISHED gold standard work
 134 publications (52 new protocols, 42 new reviews, and 40 updated reviews) of
internationally renowned quality, across all 8 defined areas of dentistry:
periodontology, operative (including endodontics) and prosthodontics, paediatric dentistry, dental
public health, oral and maxillofacial surgery, oral medicine, orthodontics, and cleft lip and/or palate
 Podcast production
 Evidence summaries for patients on our website
 Highly-accessed research*:
- Interventions for preventing oral mucositis for patients with cancer receiving treatment (n=
7,479)
- Sealants for preventing dental decay in the permanent teeth (n= 7,026)
- Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia (n= 5,686)
- Manual versus powered toothbrushing for oral health (n= 6,655)
- Fluoride varnishes for preventing dental caries in children and adolescents (n= 6,639)
*2013 access figures
PARTNERED with diverse collaborators
 More than 800 authors and 300 referees, in over 40 countries
 International expert panels of clinicians and researchers across our 8 areas of
dentistry
 IADR’s Global Oral Health Inequalities Research Network (GOHIRA)
 World Health Organisation
 International guideline developers (ADA, NICE, SIGN, SDCEP)
 The public, in an open survey about key oral health concerns
 Consumers, through our Consumer Co-ordinator
PRIORITISED within our scope
 The most globally important topics within each of our 8 areas of dentistry
 A core portfolio of 81 existing review titles that we will actively support the update of
 Identified priority topics for 15 new intervention reviews
 Undertaken 2 diagnostic test accuracy (DTA) reviews to enhance our suite of
evidence for oral cancer
 Plans to complete stalled reviews
PROMOTED evidence-based care
 International conference presentations and training
o IADR workshops;
o Professional societies, including many GA partners
 Training for researchers and clinicians
 Reviews have been linked to changing practice
 Reviews leading to the design of new RCTs
 Produced an introductory video about COHG’s research activities (over 1,200 views
to date)
PERFORMED exceptionally well
 As measured by:
o the Cochrane Editorial Unit’s quality assurance standards;
o an exponential increase of over 50% in productivity:
- Jan 1996-Sep 2010: 167 reviews published (112 new reviews; 55 updated reviews) over
165 months – 1.0 publications p/month;
- Oct 2010-Dec 2014: 82 reviews published (42 new reviews; 40 updated reviews) over 51
months – 1.6 publications p/month
o our Impact Factor (2013: 4.00), which ranks the COHG’s publications alongside
the top 3 dental journals;
o award of NIHR Incentive scheme grant to complete review on Immunotherapy
for the treatment of oral cancer.
Funding from the COHG’s 10 Global Alliance partners has made possible the employment
of a senior systematic reviewer and a research coordinator, who have been key to many
of these achievements.
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BACKGROUND
COCHRANE ORAL HEALTH GROUP
The Cochrane Oral Health Group (COHG) has an international membership of 1490 members, of which
over 860 are review authors from 42 countries. Our global panel of peer reviewers ensure our reviews
are both of high quality and clinically relevant, and our editorial board’s decision-making processes are
supported by 8 field-specific internationally expert panels of clinicians and researchers (Cleft lip and/or
palate; Dental public health; Operative and prosthodontic dentistry; Oral and maxillofacial surgery; Oral
medicine; Orthodontics; Paediatrics; Periodontology).
As of December 2014, COHG has 153 systematic reviews, 55 review updates and 60 protocols
published on the Cochrane Library, with further reviews and protocols in preparation and an additional
10 registered titles. Reviews on the Cochrane Library have an Impact Factor of 5.939 (2013).
Consequently, it is now ranked 10th of the 150 journals in the Medicine, General & Internal category and
the COHG’s Impact Factor is in the top 3 dental journals.
We have increased our collaboration and partnership working with international guideline
development groups and can demonstrate the impact of COHG reviews in reducing the duplication of
effort.
COHG GLOBAL ALLIANCE
Cochrane reviews are usually undertaken by enthusiastic individuals with some methodological help
from the editorial base. Due to increased commitments on clinicians’ and academics time, and more
complex research methods being introduced centrally by the Cochrane Collaboration, the COHG needed
to fundamentally change the way we support the profession. The Global Alliance was established to
enable an expert methodological and administrative team to support the conduct of priority reviews
ensuring their quality and timeliness.
Since 2011, we have received over £200,000 from Global Alliance partners to support this initiative.
This has enabled us to partially fund a senior systematic reviewer and research coordinator to support
the production of priority reviews, and significantly improve their methodological quality.
A consumer perspective is important to making the reviews assessable and the support received by the
GA is enabling the Group to expand its level of patient involvement and develop a strategy to engage
more globally. The COHG launched an evidence summaries section of the website for patients to use to
inform their decision-making. The first section is on tooth decay/caries, with other areas of concern
identified by the international public survey to be added in the near future.
PARTNER ORGANISATIONS
To date, the following organisations have pledged their support of COHG’s production of high quality
and clinically relevant systematic reviews by donating to the GA, either as a one-off sum, or a
commitment of several years:



British Orthodontic Society, UK (2011-2013)
Royal College of Surgeons Edinburgh (RCSEd),
UK (2011-2013)
New York University College of Dentistry, USA
(2011-2013; 2014-2018)



British Society of Paediatric Dentistry, UK
(2011-2013)
National Center for Dental Hygiene Research
& Practice, USA (2012-2015)
Canadian Dental Hygienists Association,
Canada (2012)
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

British Association of Oral Surgeons, UK
(2013-2015)
British Society of Periodontology, UK (20132015)


Mayo Clinic, USA (2013-2014)
British Association for the Study of
Community Dentistry, UK (2014 -)
Initially, we asked GA partners for a commitment of 3-year funding to establish this initiative, and we
now realise that this funding is essential to the future success of the COHG. NIHR have committed new
funding from 2015 until 2020 (at the highest tier for UK review groups), which enables us to employ
editorial staff. The GA-funded senior systematic reviewer and research coordinator have contributed
greatly to the quality and productivity of our reviews. We ask, therefore, that GA partner organisations
extend their commitment to allow us to maintain the current review output.
All GA partners have been involved in determining the process and prioritisation of reviews, including
the opportunity to nominate representatives on the international expert panels. The process identifies
the most clinically important reviews in each field of dentistry to ensure editorial base resources are
focused upon regularly maintaining their evidence on the Cochrane Library considered important by a
clinically relevant international experts (to date numbering a total of 133 panel members, across 8
expert panels) and all relevant topic authors.
During 2014, the COHG undertook extensive prioritisation activities (across 6 areas of dentistry:
periodontology, operative (including endodontic) and prosthodontic dentistry, dental public health,
oral and maxillofacial surgery, oral medicine, cleft lip and/or palate) to identify a core portfolio of
priority titles for the editorial base to maintain. The results of this were added to the previous
prioritisation processes (identical in methodology), conducted in 2011 (orthodontics) and 2013
(paediatric dentistry).
Discussions were supplemented by the addition of a small international patient survey to elicit areas of
concern for consumers, and the contribution of representatives from IADR’s Global Oral Health
Inequalities Research Network to ensure appropriate consideration to the global burden of oral disease.
The process identified 81 existing titles across 8 areas of dentistry as being priority for maintenance by
COHG, and a number of additional new priority titles to be developed by clinically and methodologically
experienced teams in due course (see Figure 1).
COHG will repeat the prioritisation process in 2017 to ensure the core portfolio is inclusive of newly
emerging interventions, trials and priority research. In the interim, COHG continues to consult the
expert panels for clinical guidance in registering any newly proposed titles, as and when required.
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Figure 1. Core portfolio of priority titles
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GA IMPACT UPON OUTPUT
At inception of the GA, after 15 years operation of the COHG, there was a total of 217 COHG publications
on The Cochrane Library (Sep 2010: 73 protocols; 111 new reviews; 33 updated reviews).
As of December 2014, an additional 134 publications have been added to The Cochrane Library
as a direct result of GA members’ support of COHG’s research activities.
The contribution of the GA is recognised on each supported publication (under External sources), with
all GA partners individually listed, as per text below:
External sources
- Cochrane Oral Health Group Global Alliance
The production of all our reviews is assisted by funding from our Global Alliance partners
(http://ohg.cochrane.org/): British Association for the Study of Community Dentistry, UK;
British Association of Oral Surgeons, UK; British Orthodontic Society, UK; British Society of
Paediatric Dentistry, UK; British Society of Periodontology, UK; Canadian Dental Hygienists
Association, Canada; Mayo Clinic, USA; National Center for Dental Hygiene Research &
Practice, USA; New York University College of Dentistry, USA; and Royal College of Surgeons of
Edinburgh, UK
This number includes 52 new protocols, 42 new reviews, and 40 updated reviews, demonstrating
considerable impact of partners’ donations.
These publications are in the following areas of dentistry:


Periodontology: 19 publications - 14%: 8 protocols; 6 new reviews; 5 updated reviews
Operative (including endodontic)/prosthodontic surgery: 33 publications - 25%: 16
protocols; 6 new reviews; 11 updated reviews
Paediatric dentistry: 14 publications - 10%: 5 protocols; 5 new reviews; 4 updated reviews
Dental public health: 7 publications - 5%: 4 protocols; 1 new review; 2 updated review
Oral/maxillofacial surgery: 19 publications - 14%: 3 protocols; 9 new reviews; 7 updated
reviews
Oral medicine: 17 publications - 13%: 7 protocols; 8 new reviews; 2 updated reviews
Orthodontics: 21 publications - 16%: 7 protocols; 6 new reviews; 8 updated reviews
Cleft lip and/or palate: 4 publications - 3%: 2 protocols; 1 new review; 1 updated review






A full list of the GA-supported publications to date follows (priority titles in bold).
As a consequence of GA support, the Cochrane Oral Health Group has:





PUBLISHED gold standard reviews;
PARTNERED diverse collaborators (both individual and organisations);
PRIORITISED globally important topics for dentistry;
PROMOTED evidence based care though presentations and informing new research; and
PERFORMED exceptionally well according to formal Cochrane standards.
We hope our existing partners will continue to support our research activities through
Global Alliance donations in the future, and we look forward to new partners
joining the GA to strengthen COHG’s gold standard research output.
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Area of Dentistry
Periodontology
(19 publications:
8 protocols;
6 reviews;
5 updated reviews)
Operative/
prosthodontic
surgery
(33 publications:
16 protocols;
6 reviews;
11 updated
reviews)
Protocols
1. Flossing for the management of periodontal
diseases and dental caries (Nov 2010)
2. Periodontal therapy for the management of
cardiovascular disease in patients with
chronic periodontitis (Jul 2011)
3. Interventions for the maintenance of the
dentition in patients treated for periodontal
disease (Oct 2011)
4. Interdental brushing for the management of
periodontal diseases and dental caries in
adults (May 2012)
5. Enamel matrix derivative for periodontal
regeneration in teeth with furcation involvement
(Mar 2013)
6. Triclosan/copolymer containing toothpastes for
oral health (May 2013)
7. Topical herbal interventions for gingivitis (Jun
2013)
8. Autologous platelet concentrates for treatment of
periodontal defects (Dec 2014)
1. Irrigants for non-surgical root canal treatment in
mature permanent teeth (Jan 2011)
2. Single crowns versus conventional fillings for
the restoration of root filled teeth (May 2011)
3. Laser therapy for dentinal hypersensitivity (Nov
2011)
4. Metal-free materials for fixed prosthodontic
restorations (Feb 2012)
5. Gingival retraction for fixed prosthodontic
treatment (Apr 2012)
6. Rubber dam isolation for restorative treatment in
dental patients (May 2012)
7. Systemic antibiotics for symptomatic apical
periodontitis and acute apical abscess in adults
(Oct 2012)
8. Interventions for replacing missing teeth:
alveolar ridge preservation techniques for oral
implant site development (Nov 2012)
9. Lasers for caries removal in deciduous and
permanent teeth (Nov 2012)
10. Professionally-applied chemically-induced
Reviews
9. Different powered toothbrushes for plaque
control and gingival health (Dec 2010)
10. Flossing for the management of
periodontal diseases and dental caries in
adults (Dec 2011)
11. Oral hygiene care for critically ill patients
to prevent ventilator-associated
pneumonia (Aug 2013)
12. Interdental brushing for the prevention
and control of periodontal diseases and
dental caries in adults (Dec 2013)
13. Triclosan/copolymer containing toothpastes
for oral health (Dec 2013)
14. Periodontal therapy for the management
of cardiovascular disease in patients with
chronic periodontitis (Aug 2014)
Updates
15. Interventions for replacing missing teeth:
treatment of peri-implantitis (Jan 2012)
16. Interventions for replacing missing teeth:
management of soft tissues for dental
implants (Feb 2012)
17. Routine scale and polish for periodontal
health in adults (Nov 2013)
18. Recall intervals for oral health in
primary care patients (Dec 2013)
19. Powered versus manual toothbrushing
for oral health (Jun 2014)
17. Interventions for replacing missing teeth:
partially absent dentition (Feb 2012)
18. One-to-one dietary interventions undertaken
in a dental setting to change dietary behaviour
(Mar 2012)
19. Single crowns versus conventional fillings
for the restoration of root filled teeth (May
2012)
20. Irrigants for non-surgical root canal treatment
in mature permanent teeth (Sep 2012)
21. Direct composite resin fillings versus
amalgam fillings for permanent or adult
posterior teeth (Mar 2014)
22. Systemic antibiotics for symptomatic apical
periodontitis and acute apical abscess in
adults (Jun 2014)
23. Interventions for replacing missing
teeth: different times for loading dental
implants (Mar 2013)
24. Operative caries management in adults
and children (Mar 2013)
25. Interventions for replacing missing teeth:
antibiotics at dental implant placement to
prevent complications (Jul 2013)
26. Interventions for replacing missing teeth:
dental implants in zygomatic bone for the
rehabilitation of the severely deficient
edentulous maxilla (Sep 2013)
27. Interventions for replacing missing teeth:
hyperbaric oxygen therapy for irradiated
patients who require dental implants (Sep
2013)
28. Antibacterial agents in composite
restorations for the prevention of dental
caries (Dec 2013)
29. Antibiotic use for irreversible pulpitis (Dec
2013)
7
Paediatric
dentistry
(14 publications:
5 protocols;
5 reviews;
4 updated reviews)
Dental public
health
(7 publications:
4 protocols;
1 review;
2 updated reviews)
whitening of teeth in adults (Feb 2013)
11. Proximal sealing for managing dental decay in
primary and permanent teeth (Mar 2013)
12. Dental cavity liners for Class I and Class II resinbased composite restorations (May 2013)
13. Hypnosis for alleviation of anxiety in adults
undergoing dental treatment (Aug 2013)
14. Home-use whitening toothpastes for whitening
teeth in adults (Jan 2014)
15. Management of gag reflex for patients
undergoing dental treatment (May 2014)
16. Adhesive restorations for the treatment of dental
non-carious cervical lesions (Dec 2014)
1. Intraoperative local anaesthesia for reduction of
postoperative pain following general anaesthesia
for dental treatment in children and adolescents
(Mar 2012)
2. Non-fluoride topical remineralising agents
containing calcium and/or phosphate for
controlling dental caries (Mar 2012)
3. Chlorhexidine versus topical fluoride treatment
for the prevention and management of dental
caries in children and adolescents (Jul 2012)
4. Xylitol-containing products for preventing dental
caries in children and adolescents (Sep 2013)
5. Interventions for increasing acceptance of local
anaesthetic in children having dental treatment
(Mar 2014)
1.
2.
3.
4.
Oral/
maxillofacial
surgery
(19 publications:
3 protocols;
1.
2.
Primary school-based behavioural interventions
for preventing caries (Oct 2011)
Maternal consumption of xylitol for preventing
dental decay in children (Nov 2012)
Oral health educational interventions for
nursing home staff and residents (May 2013)
Water fluoridation for the prevention of
dental caries (Dec 2013)
Dental extractions prior to radiotherapy to
the jaws for reducing post-radiotherapy
dental complications (Dec 2010)
Interventions for the management of dry
mouth: non-systemic therapies (Jan 2011)
30. Replacement versus repair of defective
restorations in adults: amalgam (Feb
2014)
31. Replacement versus repair of defective
restorations in adults: resin composite
(Feb 2014)
32. Interventions for replacing missing teeth:
different types of dental implants (Jul
2014)
33. Slow-release fluoride devices for the
control of dental decay (Nov 2014)
6.
Fluoride supplements (tablets, drops,
lozenges or chewing gums) for preventing
dental caries in children (Dec 2011)
7. Preoperative analgesics for additional
pain relief in children and adolescents
having dental treatment (Sep 2012)
8. Interventions for treating traumatised
permanent front teeth: luxated (dislodged)
teeth (Apr 2013)
9. Interventions for the restorative care of
amelogenesis imperfecta in children and
adolescents (Jun 2013)
10. Intraoperative local anaesthesia for reduction
of postoperative pain following general
anaesthesia for dental treatment in children
and adolescents (Dec 2014)
5. Primary school-based behavioural
interventions for preventing caries (May
2013)
11. Sedation of children undergoing dental
treatment (Mar 2012)
12. Sealants for preventing dental decay in
the permanent teeth (Mar 2013)
13. Fluoride varnishes for preventing
dental caries in children and
adolescents (Jul 2013)
14. Pulp treatment for extensive decay in
primary teeth (Aug 2014)
6.
7.
4.
5.
Pharmacological interventions for pain in
patients with temporomandibular
disorders (Oct 2010)
Interventions for the treatment of oral
cavity and oropharyngeal cancer:
Screening programmes for the early
detection and prevention of oral cancer
(Nov 2010)
Screening programmes for the early
detection and prevention of oral cancer
(Nov 2013)
13. Domestic violence screening and
intervention programmes for adults with
dental or facial injury (Dec 2010)
14. Interventions for the treatment of oral
cavity and oropharyngeal cancer:
8
9 reviews;
7 updated reviews)
3.
Interventions for the treatment of oral and
oropharyngeal cancers: targeted therapy and
immunotherapy (Feb 2013)
6.
7.
8.
9.
10.
11.
12.
Oral medicine
(17 publications:
7 protocols;
8 reviews;
2 updated reviews)
1.
2.
3.
4.
5.
6.
7.
Orthodontics
(21 publications:
7 protocols;
6 reviews;
1.
2.
Interventions for myogenous
temporomandibular disorder (TMD) patients
(Nov 2010)
Interventions for the management of dry mouth:
non-pharmacological interventions (Feb 2012)
Clinical assessment to screen for the
detection of oral cavity cancer and potentially
malignant disorders in apparently healthy
adults (Nov 2012)
Diagnostic tests for oral cancer and
potentially malignant disorders in patients
presenting with clinically evident lesions (Dec
2012)
Interventions for the management of taste
disturbances (Apr 2013)
Topical interventions for recurrent aphthous
stomatitis (mouth ulcers) (Dec 2013)
Interventions for the management of oral ulcers
in Behçet's disease (Mar 2014)
8.
Interventions for correcting relapse of the lower
front teeth after orthodontic treatment (Oct
2010)
Direct versus indirect bonding for bracket
20.
9.
10.
11.
12.
13.
14.
15.
21.
radiotherapy (Dec 2010)
Arthroscopy for temporomandibular
disorders (May 2011)
Interventions for the management of dry
mouth: topical therapies (Dec 2011)
Interventions for the management of
temporomandibular joint osteoarthritis (Apr
2012)
Dental extractions prior to radiotherapy to
the jaws for reducing post-radiotherapy
dental complications (Feb 2013)
Ibuprofen and/or paracetamol
(acetaminophen) for pain relief after surgical
removal of lower wisdom teeth (Dec 2013)
Interventions for iatrogenic inferior alveolar
and lingual nerve injury (Apr 2014)
Surgical techniques for the removal of
mandibular wisdom teeth (Jul 2014)
Psychosocial interventions for the
management of chronic orofacial pain (Nov
2011)
Systemic interventions for recurrent aphthous
stomatitis (mouth ulcers) (Sep 2012)
Antibiotics to prevent complications following
tooth extractions (Nov 2012)
Local interventions for the management of
alveolar osteitis (dry socket) (Dec 2012)
Interventions for the management of dry
mouth: non-pharmacological interventions
(Sep 2013)
Clinical assessment to screen for the
detection of oral cavity cancer and
potentially malignant disorders in
apparently healthy adults (Nov 2013)
Interventions for the management of oral
ulcers in Behçet's disease (Sep 2014)
Interventions for the management of taste
disturbances (Nov 2014)
Adhesives for bonded molar tubes during
fixed brace treatment (Jun 2011)
Treatments for adults with prominent lower
front teeth (May 2012)
chemotherapy (Apr 2011)
15. Interventions for the treatment of oral
and oropharyngeal cancers: surgical
treatment (Sep 2011)
16. Surgical removal versus retention for
the management of asymptomatic
impacted wisdom teeth (Jun 2012)
17. Interventions for the management of
mandibular fractures (Jul 2013)
18. Antibiotics for the prophylaxis of
bacterial endocarditis in dentistry (Oct
2013)
19. Interventions for replacing missing
teeth: augmentation procedures of the
maxillary sinus (May 2014)
16. Interventions for preventing oral
mucositis for patients with cancer
receiving treatment (Apr 2011)
17. Interventions for treating oral lichen
planus (Jul 2011)
26. Orthodontic treatment for deep bite and
retroclined upper front teeth in children
(Jan 2012)
27. Extraction of primary (baby) teeth for
9
8 updated reviews)
3.
4.
5.
6.
7.
placement in orthodontic patients (Jul 2012)
Laceback ligatures for controlling anchorage in
patients undergoing fixed orthodontic treatment
(Aug 2012)
Orthodontic treatment for bimaxillary
proclination in children and adults (Nov 2012;
withdrawn Mar 2014 - link unavailable)
Non-pharmacological interventions for
alleviating pain during orthodontic treatment
(Dec 2012)
Adjunctive surgical procedures for
accelerating tooth movement in patients
undergoing orthodontic treatment (Jun 2013)
Non-surgical adjunctive interventions for
accelerating tooth movement in patients
undergoing fixed orthodontic treatment (Dec
2013)
22. Interventions for managing relapse of the
lower front teeth after orthodontic treatment
(Sep 2013)
23. Orthodontic treatment for prominent
lower front teeth (Class III malocclusion)
in children (Sep 2013)
24. Orthodontic treatment for distalising upper
first molars in children and adolescents (Oct
2013)
25. Enamel etching for bonding fixed orthodontic
braces (Nov 2013)
28.
29.
30.
31.
32.
33.
Cleft lip and/or
palate
(4 publications:
2 protocols;
1 review;
1 updated review)
1.
2.
Pre-surgical orthopaedics (PSO) for infants with
complete cleft lip and palate (Dec 2010)
Maxillary distraction osteogenesis versus
orthognathic surgery for cleft lip and palate
patients (Feb 2013)
3.
Secondary bone grafting for alveolar cleft in
children with cleft lip or cleft lip and palate
(Jun 2011)
4.
unerupted palatally displaced
permanent canine teeth in children (Dec
2012)
Initial arch wires for tooth alignment
during orthodontic treatment with fixed
appliances (Apr 2013)
Orthodontic treatment for prominent
upper front teeth (Class II malocclusion)
in children (Nov 2013)
Fluorides for the prevention of early tooth
decay (demineralised white lesions) during
fixed brace treatment (Dec 2013)
Orthodontic treatment for posterior
crossbites (Aug 2014)
Reinforcement of anchorage during
orthodontic brace treatment with
implants or other surgical methods (Aug
2014)
Orthodontic and orthopaedic treatment for
anterior open bite in children (Sep 2014)
Feeding interventions for growth and
development in infants with cleft lip,
cleft palate or cleft lip and palate (Feb
2011)
10