Download Triosyn Wound Dressing

Prototype
Triosyn Corp.
1191 South Brownell Road
Williston, VT 05495
U.S.A.
Triosyn® Wound Dressing
(U.S. Patents 6,045,820)
Introduction:
®
The Triosyn Wound Dressing represents a major breakthrough in wound/disease
management and care. This particular dressing not only protects the wound from
infection and bacterial contamination, but it also provides gaseous exchange, and
absorbs fluid exudates and toxic components; it also kills bacteria, viruses and fungi
found on the skin on contact and on demand. Unlike most wound dressings, which
®
also provide gaseous exchange, the Triosyn Wound Dressing destroys these biocontaminants that would escape into the atmosphere.
Background:
Wound Dressings are classified into two types of dressings, which include
breathable and occlusive. An occlusive dressing is a wound dressing that has the
ability to transmit gases and water vapor from a wound surface to the atmosphere,
and also keeps the wound moist. A breathable dressing is the more traditional type
of wound dressing that simply allows high breathability.
®
The Triosyn Wound Dressing integrates both types of dressings, as it keeps the
wound dry by applying dry dressing (no moisture is added to the wound as in other
occlusive dressings); it is capable of absorbing exudates, and allows gases and
water vapor from the wound surface to transmit to the atmosphere.
Characteristics:
®
The Triosyn Wound Dressing is similar to an over-the-counter bandage composed
of three layers of materials: the backing material, center material, Triosyn, and
finally the mesh. Its shape is square and is produced in various sizes to attend to
various applications.
This backing material has one side with an adhesive layer for the center material to
attach to, and also to adhere directly to the skin. This material is breathable to allow
air and moisture to interact with the skin, due to the direct contact. The material is
tan Spunlaced non-woven, which is typical of most bandages.
The center material adheres directly to the center of the backing material. This
material also has one adhesive layer, which is covered entirely by Triosyn beads.
The non-adhesive side of this material is placed on the adhesive side of the backing
material. This material is non-woven, which is breathable to absorb moisture from
the skin.
Technology for the control of infectious disease!
The Triosyn, which is attached to the center material of the Wound Dressing,
are shaped as spherical beads.
The mesh is a Polyethylene Non-woven Fabric (thin, porous). The purpose of
this material is to cover the Triosyn beads, in the event that a bead should
detach from the center material; it will protect the healing wound from a bead
becoming trapped in the skin.
A liner with a wax coating adheres to the adhesive side of the backing material;
this liner protects the wound dressing from becoming contaminated before
applying to the skin.
The Triosyn Wound Dressing Benefits:
•
Absorbs fluid exudates and toxic components.
•
Protects wound site from infection, bacterial, fungal or viral
contamination, and other environmental biocontaminants.
•
Provides gaseous exchange and allows for oxygen entry and water
vapor escape.
•
Used in numerous applications including: a common bandage or postsurgery dressing to prevent infection or more serious skin disorders that
require killing of bacteria, viruses, and fungi, including but not limited to:
herpes, ulcers, small pox, tuberculosis, skin disorders resulting from
disease (i.e. renal).
•
Traps bio-contaminates and doesn’t allow them to escape into the
atmosphere.
•
Promotes epithelialization or new tissue growth where reconstruction
takes place in four stages: detachment, migration, proliferation, and
differentiation
Technology for the control of infectious disease!
Third Party and Internal Testing:
Tests
Challenge
Results
Biocidal Wound Dressing and
Wound Treatment:
Microbiological Toxicological
Comparative Study
Pseudomonas
aeruginosa at
9
10 CFU/ml
Staphylococcus
aureus at
9
10 CFU/ml
Complete inoculum
eradication & wound
protection from infection
was observed.
Bacteriocidal Effect of Triosyn
Impregnated Wound Dressing
CBIAC Program:
Skin Decontamination Project
Bacillus Abortus
Complete eradication.
In Vitro Evaluation of the
Efficacy of Novel Wound
Dressings Containing a
Thermal Fused BroadSpectrum Interactive Iodinated
Polymer (Triosyn®) in
Devitalizing MS2 Viral
Particles
Hand Decontamination Project
CBIAC program:
Body Bag Project
Bacillus subtilis
5
var niger at 10
CFU/ml
MS2 phage at
6
10 PFU/ml
Klebsiella terrigena
6
at 10 CFU/ml
MS2 Viral Particles
4
At 10 PFU/ml
Bacillus subtilis var niger
Showed 98.556%
reduction
MS2 phage produced
99.999% reduction
Klebsiella terrigena
showed 99.986%
reduction
99.796% reduction
against MS2 phage after
24 hours
99.355% reduction after
48 hours
4 log reduction
Serratia
marcescens
6
10 CFU
7
MS2 phage at 10
PFU/ml
4 log reduction against
MS2 Phage
Bacillus subtilis
var niger (BG) at
7
10 CFU/ml
3 log reduction against
BG spores
Technology for the control of infectious disease!