Download Annual Report 2010-2011

Annual Report
2010-2011
Table of Contents
Opening Messages................................................................................................................................ 2
Prof Thomas Martin (Australian Catholic University).................................................................... 2
Prof Richard Fox (St Vincent’s Hospital Melbourne).................................................................... 3
Prof Arthur Shulkes (University of Melbourne).............................................................................. 3
.CvRC Directors............................................................................................................................. 4
Introducing CvRC................................................................................................................................ 5
Background................................................................................................................................... 5
Benefits of CvRC.......................................................................................................................... 5
Vision............................................................................................................................................ 5
Aims & Objectives........................................................................................................................ 5
Governance Structure.................................................................................................................. 6
CvRC Team............................................................................................................................................ 7
CvRC Programs.................................................................................................................................. 10
1. Interventional Cardiology......................................................................................................... 10
2. Health Outcomes Research..................................................................................................... 10
3. Prevention of CVD................................................................................................................... 11
4. Vascular and Cardiac Surgery................................................................................................. 11
5. Cardiac Services...................................................................................................................... 12
6. Mental Health & Wellbeing...................................................................................................... 12
7. Psychosocial Research........................................................................................................... 13
8. Basic CVD Science.................................................................................................................. 13
9. Heart Failure and Imaging....................................................................................................... 14
CvRC Partnerships............................................................................................................................ 15
Community Engagement...................................................................................................................... 15
Events & Highlights........................................................................................................................... 16
CvRC Launch.............................................................................................................................. 16
Australia & New Zealand Optical Tomography (ANZ OCT) Workshops...................................... 18
Awards......................................................................................................................................... 19
Media Coverage................................................................................................................................... 20
Print............................................................................................................................................. 20
Online.......................................................................................................................................... 20
Television..................................................................................................................................... 21
Research Outcomes........................................................................................................................... 22
Grants.......................................................................................................................................... 22
Book Chapters............................................................................................................................. 24
Publications................................................................................................................................. 24
Presentations............................................................................................................................... 29
Affiliated Outcomes........................................................................................................................... 31
Affiliated Books............................................................................................................................ 31
Affiliated Book Chapters.............................................................................................................. 31
Affiliated Publications................................................................................................................... 31
CvRC Annual Report 2010-2011
1
Opening Messages
Professor Thomas Martin
Deputy Vice-Chancellor (Research)
Australian Catholic University
In times when the Bradley review, the Grattan Institute report and other global impacts
are re-shaping Australia’s higher education sector, the Australian Catholic University
has continued to progress and excel in many ways. An outstanding example of this
progress is the research undertaken at the Faculty of Health Sciences which is
increasing at a rapid level in both quality and quantity.
One success story in the Faculty of Health Sciences, that is envisioned to grow, is
the Cardiovascular Research Centre (CvRC). This Centre has been established in
collaboration with St Vincent’s Hospital Melbourne and the University of Melbourne
to address the important field of cardiovascular disease (CVD), a major healthcare
priority of the government.
CvRC reaches across different disciplines that are recognised as impacting directly
or indirectly on CVD and its risk factors. The researchers not only collaborate crossinstitutionally, but also work in multidisciplinary teams. At CvRC, nurses, cardiologists, surgeons, psychologists
and allied health staff all combine their efforts to achieve research outcomes that impact holistically on the care
management of CVD. Not only does this approach foster synergy by combining research efforts and transferring
knowledge across different fields, it also helps to overcome traditional barriers between research and practice. ACU
is proud to be part of such an innovative undertaking.
The Cardiovascular Research Centre is directed by Prof Linda Worrall-Carter (Professor of Cardiovascular Nursing
at ACU) and Prof Robert Whitbourn (a Clinical Cardiologist at St Vincent’s). They spearhead a team of nine heads
of program, each addressing different aspects of CVD. I would like to congratulate both of them on their vision and
passion for this initial project, which garnered support from ACU, St Vincent’s Executive and senior academic staff
from the University of Melbourne.
This Annual Report covers the inaugural years of CvRC, showcasing the enormous potential of this collaboration
and I would like to congratulate the CvRC team for their efforts. With new projects already in the making, CvRC is
on its way to substantially contribute to achieving ACU’s strategic goals in conjunction with its partner institutions. I
commend this report to you and am looking forward to future outcomes.
Prof Thomas Martin
2
Professor Richard Fox
Director of Research
St Vincent’s Hospital Melbourne
It is with great pleasure that I recommend this inaugural report of the Cardiovascular
Research Centre.
The report clearly displays early but strong outcomes from this new research endeavour
by St Vincent’s Hospital and its partners. Cardiovascular disease is a high research
priority due to its burden on the community and one which needs addressing from many
different perspectives. St Vincent’s Hospital has had a longstanding collaboration with
the University of Melbourne for many years now in medical training and research. Also,
the Australian Catholic University has a strong nursing tradition here at St Vincent’s
Hospital in Melbourne. The uniqueness of this triad model cannot be undervalued; in
particular, the interdisciplinary approach, bringing nurses, medical and allied health
professionals together to address important ways to improve patient care, is one of
many challenges.
In the relatively short time that the CvRC has been established, it is clear from this report to see that there have been
many inroads and the CvRC has made an excellent start. I look forward to this important ongoing collaboration.
Prof Richard Fox
Professor Arthur Shulkes
Associate Dean (Research), Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne
Professorial Fellow, Department of Surgery at Austin Health, University of Melbourne
It is my pleasure to recommend this inaugural Annual Report of the Cardiovascular
Research Centre (CvRC).
The establishment of CvRC is an innovative concept that represents a collaboration
across three institutions, namely St Vincent’s Hospital Melbourne, the Australian
Catholic University and the University of Melbourne. Under the leadership of Prof Robert
Whitbourn and Prof Linda Worrall-Carter they have managed to create synergies in
the research priority area of cardiovascular disease. CvRC offers a new way to explore
and advance this field of research through truly multidisciplinary research.
CvRC’s aim is to conduct cardiovascular research with basic science researchers
informing clinicians and vice-versa. The Centre’s competitive edge is the strong
collaborative approach through conducting multidisciplinary research and emphasising
on the strengths of each institution. Furthermore, it underlines our obligation as
researchers and higher education institutions to build research capacity and provide
training for upcoming researchers as well as to inform evidence-based practice. Implementation into health practice
of advances in knowledge is a key responsibility of the CvRC and is embedded into all its activities.
Once again, I congratulate Prof Worrall-Carter and Prof Whitbourn on this endeavour. This report comprehensively
summarizes the activities of CvRC’s key researchers over the first two years and I highly commend this report to you.
Prof Arthur Shulkes
CvRC Annual Report 2010-2011
3
Opening Messages (cont.)
Professor Robert Whitbourn & Professor Linda Worrall-Carter
CvRC Directors
We are very pleased to present you with this
inaugural CvRC Annual report.
The Cardiovascular Research Centre has been a
vision for a number of years and many staff have
worked together in a virtual research capacity
until we formally got together in August 2009 and
launched the Centre late in 2010.
We were fortunate to have significant partnership
support for this initiative; in particular from ACU
where we were able to secure funding for our office
space in the VECCI Building/Albert Street. Equally
as important as support from the institutions, is the
support we receive from our colleagues. We have
a vibrant team of researchers who work together
from ACU, St Vincent’s and the University of
Melbourne.
Cardiovascular disease has many different facets and to address it effectively and efficiently, researchers and
clinicians from several disciplines have combined their efforts and knowledge by establishing CvRC. Furthermore,
we have overcome the traditional barriers to collaboration between universities by combining two universities’ areas
of expertise. In addition, being linked to St Vincent’s Hospital allows for the quick implementation and translation of
our research in order to effectively conduct “bench to bedside” research.
It is our aim to build a sustainable research platform that fosters innovative inquiry and finds new ways for improved
patient care.
All of this would not have been possible without the ongoing support of key people in all three partner organisations.
It was their continuous commitment that eventually made CvRC possible for which we are immensely grateful. We
hope you enjoy this report that covers the research activity to date.
Prof Rob Whitbourn & Prof Linda Worrall-Carter
4
Introducing CvRC
Background
The Cardiovascular Research Centre (CvRC) was established in 2009 as a joint collaboration between St Vincent’s
Hospital Melbourne, the Australian Catholic University (ACU) and the University of Melbourne (UniMelb). CvRC
is committed to excellence in cardiovascular research, with a focus on basic, clinical research and improvement
of health outcomes. Professor Robert Whitbourn (Clinical Cardiologist and Director of Cardiac Catheterization
Laboratories at St Vincent’s) and Professor Linda Worrall-Carter (Professor of Cardiovascular Nursing at ACU) are
co-directors and on the board of management that is guiding the strategic direction of the Centre.
CvRC is a very innovative research initiative which combines
two universities’ areas of strength: the Melbourne Medical
School at the University of Melbourne and the School
of Nursing & Midwifery at ACU. It also showcases how
traditional barriers to collaboration between universities can
be overcome. Furthermore, being linked to a hospital allows
for the direct implementation and translation of this research.
CvRC’s aim to build research capacity and increase
collaborative research is beneficial for all partners in a
long-term perspective. It provides a sustainable research
platform fostering innovative research questions due to
the multidisciplinary approach and the synergetic effects of
working cross-institutionally. Funding for this endeavour is
provided by the partners (ACU, UniMelb, St Vincent’s) and is
supplemented through a variety of means including private
and public grants from a number of sources.
Vision
• To lead research in cardiovascular
disease, from basic science to improved
clinical outcomes;
• To engage in collaborative research
locally, nationally and internationally;
• To cultivate a multidisciplinary approach
between the health specialities through
building capacity in research training;
• To foster a clinical interface between
research, education and clinical practice.
There are very few clinical research centres such as this that offer “bench to bedside” research and that come with
a suite of currently nine different research programs covering research topics from Basic Science through to Health
Outcomes/Translational Research. Each program focuses on a different aspect of cardiovascular disease (CVD).
This enables the partners to critically examine this field by applying different angles to find a holistic solution that
can effectively reduce the risk of CVD.
Benefits of CvRC
CvRC focuses on sustainable research productivity which
will provide benefits to all three partners. Furthermore, the
knowledge resulting from the research undertaken and the
enhanced research capacity will, and already does, produce
innovation and efficiencies to benefit the broader community.
The ultimate goal is to establish a dynamic knowledge base
to efficiently and effectively address the social and economic
burden represented by CVD that can successfully compete
in the international arena. The expected flow-on effects are
improved quality of life and social cohesion for patients, and
sustained economic growth.
Additionally, the Centre supports and mentors students and
clinical staff who undertake research training for Honours,
Masters and Doctoral degrees. The team at CvRC is also
committed to building capacity in early career researchers
(ECRs) to foster young talent in this important field of
research.
Aims & Objectives
• To conduct both basic and clinical
outcomes-focused research;
• To provide research training and
higher education career pathways for
medical, nursing and other allied health
professionals;
• To educate the public and develop better
health care initiatives for the prevention
and treatment of cardiovascular diseases.
CvRC Annual Report 2010-2011
5
Introducing CvRC (cont.)
Governance Structure
The Cardiovascular Research Centre is overseen
by two Directors; one is a clinical nursing Professor,
funded equally as a joint appointment by St Vincent’s
and ACU, and the second is a clinical cardiologist
appointed by St Vincent’s with adjunct appointments
at UniMelb and ACU. The Deputy Director holds a
joint position between the University of Melbourne
and St Vincent’s Hospital. Thus, the responsibility to
ensure efficient and effective management sits with
all three partners.
CvRC
The governing committee is the CvRC Board. It
is responsible for directing strategy, approving
policies, monitoring performance, as well as
assuring financial accountability and adherence to
contractual obligations. The Board accommodates
all three partners to ensure everybody’s interests
are represented. There is also a Heads of Program
Committee which is responsible for leading the
management and operational function of CvRC.
St Vincent’s Hospital
Melbourne
Prof Robert Whitbourn
Prof Linda Worrall-Carter (joint)
A/Prof Andrew Wilson (joint)
A/Prof Andrew MacIsaac
Prof David Castle
Dr Andrew Newcomb
A/Prof David Prior (joint)
Dr Peter Mossop
Overall, three programs of research are headed by academics from ACU and the University of Melbourne
respectively, another is co-headed between the two. Another four programs are headed by St Vincent’s Hospital
staff. Each program has a team attached to it which is occasionally cross-institutionally staffed. Furthermore, the
different programs collaborate with each other on project, grants, publications and supervisions underlining the
collaborative nature of the Centre.
St Vincent’s CEO &
Executives
Deputy VC
(Research & Academic)
CvRC Board:
Director:
Co-Director:
Deputy Director:
Executive Members:
St Vincent’s Research
Directorate
Prof Robert Whitbourn
Prof Linda Worrall-Carter
A/Prof Andrew Wilson
Prof Thomas Martin
Prof Michelle Campbell
Prof Janet Hiller
Prof Richard Fox
Prof Arthur Shulkes
Ms Miriam Spano
Executive Dean
Faculty of Health
Sciences
CvRC PROGRAMS:
6
Prevention of
CVD
Mental Health
& Wellbeing
A/Prof Wilson
Prof Castle &
A/Prof Edward
Health
Outcomes
Research
Prof Worrall-Carter
Psychosocial
Research
Interventional
Cardiology
Cardiac
Services
Prof Thompson &
A/Prof Ski
Prof Whitbourn
A/Prof MacIsaac
Vascular &
Cardiac
Surgery
Dr Newcomb
Basic CVD
Science
Heart Failure &
Imaging
Prof Kelly
A/Prof Prior &
Dr Mossop
CvRC Team
Professor Robert Whitbourn
CvRC Director
Program Head of Interventional Cardiology
Prof Robert Whitbourn is one of the founding Directors of the CvRC. In his clinical role he is
the Director of Cardiac Catheterization Laboratories at St Vincent’s Hospital Melbourne. He
is also an Associate Professor at the Department of Medicine, the University of Melbourne
and an Adjunct Professor to ACU and the Stanford University Medical Center.
His primary interest is interventional cardiology and new device therapies for coronary
artery disease. He has led numerous trials of stents and novel cardiac devices, including
systemic hypothermia for metabolic protection of ischaemia and performed the first cases
in man of renal sympathetic denervation for resistant hypertension.
Professor Linda Worrall-Carter
CvRC Director
Program Head of Health Outcomes Research
Prof Linda Worrall-Carter is the other founding Director of the CVRC. Besides this she is
also Director of the St Vincent’s Centre for Nursing Research (SVCNR) and Deputy Director
of the National Centre for Clinical Outcomes Research (NaCCOR), which is a university
priority research centre at ACU.
Her major areas of expertise in CVD include risk assessment and prevention, women and
CVD, as well as exploring models of care around CVD and depression. She is a strong
advocate for nurses in research and has established effective pathways for implementing
academic research into practice.
Associate Professor Andrew Wilson
CvRC Deputy Director
Program Head of Prevention of CVD
A/Prof Andrew Wilson has been the Deputy Director of CvRC since 2011. He is also a David
Bickart Clinician Research Fellow at the University of Melbourne and works clinically as a
cardiologist at St Vincent’s Melbourne. He has expertise in cardiovascular medicine and
maintains international links with Stanford University, USA.
His particular interest is the prevention of atherosclerosis including risk factor modificationm
especially lipid management. He has published research into the detection of biomarkers
for cardiovascular disease.
Professor David Thompson
Program Head of Psychosocial Research
Professor Thompson is Professor of Nursing at ACU and leads the Senior Proven Research
Team within the Faculty of Health Sciences. He brings extensive clinical and research
experience in cardiac care and rehabilitation to CvRC. He is an international leading
authority in cardiovascular nursing, having made significant contributions in synthesising
and evaluating the evidence for cardiac rehabilitation, designing and evaluating novel early
brief psychosocial interventions for cardiac patients and partners, as well as developing
and validating disease-specific health-outcome measures for cardiovascular disease. Prof
Thompson’s major interests are in developing disease-specific patient-reported outcome
measures and designing and evaluating novel psychosocial interventions.
CvRC Annual Report 2010-2011
7
CvRC Team (cont.)
Associate Professor Chantal Ski
Co-Head of Psychosocial Research
Associate Professor Ski co-heads the program of Psychosocial Research together with
Prof Thompson. With an academic background in psychology, her particular expertise lies
in addressing the cognitive aspects of cardiovascular disease via the development and
evaluation of novel interventions that address the psychosocial aspects of cardiovascular
disease, and also the assessment of outcome measures including scale development and
psychometric analysis.
Associate Professor Andrew MacIsaac
Program Head of Cardiac Services
Associate Professor Andrew MacIsaac is the Deputy Chief Medical Officer, Acting Director
of Cardiac Services and Director of Cardiology at St Vincent’s Hospital Melbourne. He
is Chair of both the Continuing Education and Recerfication Committee (CERC) and the
Council of Interventional Cardiologists of the Cardiac Society of Australia and New Zealand.
Professor David Castle
Program Head of Mental Health and Wellbeing
Prof David Castle is currently Chair of Psychiatry at St Vincent’s Health and the University
of Melbourne. Prof Castle’s extensive clinical, epidemiological and qualitative mental health
research experience has spanned a number of domains. His clinical and research expertise
offers the CvRC a unique skill set.
His clinical and research interests span over a number of key areas in relation to psychosocial
treatment interventions. A current area of particular interest is the physical health care of
the mentally ill. He also has internationally acclaimed expertise in the area of body image
disorders, and his work on body dysmorphic disorder is widely known.
Associate Professor Karen-leigh Edward
Deputy Head of Mental Health and Wellbeing
A/Prof Edward is the deputy head of the Mental Health and Wellbeing program. Besides this
she is the Director/Chair of the Nursing Research Unit (NRU) that is positioned between St
Vincent’s and Mercy Private Hospital and the Australian Catholic University. She is also an
Associate Professor of Nursing Research at ACU.
A/Prof Edward’s research interests include resilience, recovery and re-engagement, physical
and mental health, and professional issues in nursing. She has expertise in the development
of clinical pathways for depression in people with cardiac disease and research related to
resilience and chronic conditions as well as women and CVD.
8
Associate Professor David Prior
Program Head of Heart Failure & Imaging
A/Prof Prior is Director of Non-invasive Cardiac Imaging and Head of Cardiology & Heart
Failure Outpatient Clinics at St Vincent’s Hospital Melbourne. He is also an Associate
Professor at the University of Melbourne and a research fellow at St Vincent’s Institute of
Medical Research.
He has a special interest in echocardiography, heart failure, assessment of cardiac function,
pulmonary hypertension and sports cardiology. A/Prof Prior’s research has investigated noninvasive assessment of myocardial function in athletes and patients with heart failure, the
role of echocardiography in diagnosis and prognosis in heart failure, as well as pulmonary
hypertension.
Dr Peter Mossop
Deputy Head of Heart Failure & Imaging
Dr Peter Mossop is Director of Vascular Interventional Radiology at St Vincent’s Hospital
Melbourne. Dr Mossop’s major research interest focuses on the development of novel
endovascular device design and its application to aortic pathology.
He is currently on a sabbatical year in Europe and will return in 2012.
Dr Andrew Newcomb
Program Head of Vascular and Cardiac Surgery
Dr Newcomb is currently the Acting Director of the Cardiothoracic Surgery Department
at St Vincent’s Hospital Melbourne and is also an Honorary Clinical Senior Fellow in the
Department of Surgery at the University of Melbourne.
Dr Newcomb’s research interests include vascular biology of coronary bypass grafts, the
relationship with metabolic syndrome and the function of these grafts, development of a
source of cardiac specific stem cells, and minimally invasive approaches to the surgical
treatment of cardiovascular disease.
Professor Darren Kelly
Program Head of Basic CvD Science
Prof Kelly is the Professorial Fellow and Research Training Director for the Eastern Hill
Academic Centre at the University of Melbourne. In this capacity he also is the Director of
Biomedical Research in the Department of Medicine at St Vincent’s Hospital Melbourne.
Furthermore, he is the CEO of Fibrotech Therapeutics, a company that focuses on
developing orally active anti-fibrotic inhibitors to treat the underlying pathological fibrosis
that occurs in kidney and heart failure.
He is a recognised expert in progressing pre-clinical novel interventions and developing
experimental models of renal and cardiac disease. Prof Kelly’s focus is on transferring his
knowledge in industry, biotechnology and research into a mentoring/leadership role, as well
as developing new links between biomedical sciences and clinical research.
CvRC Annual Report 2010-2011
9
CvRC Programs
1. Interventional Cardiology
Program Head: Prof Robert Whitbourn
Prof Whitbourn and his team are interested in the early and effective intervention of CVD. They conduct a variety
of clinical trial studies that vary from drug eluting stent studies and drug trials to trialling first-in-man devices with
the overall aim to reduce the death rate resulting from cardiac events. Prof Whitbourn has been involved in many
successful trials and has supported the pathway to get innovative products market-ready to improve patient care.
Projects include:
• Percutaneous Aortic Valves (Corevalve study)
• BioAbsorbable Stents study
• BRANCH Bifurcation Stent study
• Refractory Hypertension: Renal Sympathetics Radiofrequency Ablation
• Platinum QCA & WH Sent study
• Coronary Sinus Contrast Scavenger: Osprey study
Researchers and students:
Dr Andre La Gerche. The echo/heart failure research group studies abnormalities of cardiac function using
ultrasound techniques. PhD, University of Melbourne – completed 2010.
Dr Jamie Layland. Assessing the function of small coronary blood vessels in heart attacks. MD, University of
Melbourne – completed 2010.
2. Health Outcomes Research
Program Head: Prof Linda Worrall-Carter
This program is concentrating on the implementation of research results into clinical practice. It pays particular
attention to the role that nurses play in the health care delivery. Prof Worrall-Carter and her team have successfully
trialled a nurse-led clinic at St Vincent’s Melbourne as well as other nurse-led models that are being implemented
in the health care delivery for CVD patients.
Projects include:
• Nurse-led (CVD) risk intervention screening clinic
• Nurse-led cardiac risk assessment clinic for Depression & Anxiety and Smoking Cessation
• An audit of current screening and referral mechanisms towards the recognition and treatment for depression in
people with cardiac disease
• Improving depression and anxiety screening of patients with heart disease: Implementing a multi-disciplinary
clinical pathway
Researchers and students:
Ms Jenni Hicks. Systematic review: Gender differences in 12-month outcomes of patients with primary percutaneous
coronary intervention after acute myocardial infarction? BN Honours, Australian Catholic University – completed
2011.
Mr Aaron Conway. Sedation practices within the cardiac catheter laboratory. PhD, Australian Catholic University.
Mr Malcolm Elliott. Adverse events following discharge from intensive care. PhD, Australian Catholic University.
Ms Lisa Kuhn. Diagnose and Manage Early: Women’s ischaemia and infarction (DaME II). PhD, Australian Catholic
University.
Ms Elizabeth Scruth. Women and cardiovascular disease. PhD, Australian Catholic University.
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3. Prevention of CVD
Program Head: A/Prof Andrew Wilson
The Prevention program looks at innovative ways to tackle CVD by addressing the established primary and secondary
risk factors that may lead to a cardiac event. It is believed that by reducing the risks and educating patients the
mortality rate can be decreased and the quality of life of people who live with chronic cardiac disease can be improved.
Projects include:
• Identification of a novel inflammatory biomarkers
• Plasma proteomics
• Inflammation and atherosclerosis
• Abnormalities in Nitric Oxide metabolism role of DDAH/ADMA (Dimethylarginine dimethylaminohydrolase/
Asymmetric dimethylarginine)
• Links between obesity, insulin resistance and CVD
• Prevention of Atherosclerosis
Researchers and students:
Dr Jamie Layland. Assessing the function of small coronary blood vessels in heart attacks. MD, University of Melbourne
– completed 2010.
Dr Melinda Wong. Rheumatoid arthritis, cardiovascular disease and inflammation… and the effect of rheumatoid
arthritis drug therapies on this musketeer trio. DMedSci, University of Melbourne – completed 2010.
Mr Paul-Jon Goh. Insulin resistance and obesity: Role of inflammation and AMP kinase. Advanced Medical Science
student, University of Melbourne.
Ms Sophie Hofferberth. The role of insulin resistance in perioperative dysglycaemia, metabolic syndrome and
dysfunctional nitric oxide metabolism. BMedSci, University of Melbourne.
Dr Stuart Murch. Assessment of right ventricular adaptation to pulmonary hypertension. DMedSci, University of
Melbourne.
Mr Dharshan Palasubramnain. New biomarkers of peripheral vascular disease and coronary artery disease using
throughput proteomics. Advanced Medical Science student, University of Melbourne.
Ms Zuhaili Zahari. Investigating the relationship of pericardial fat and inflammation. Advanced Medical Science student,
University of Melbourne.
4. Vascular and Cardiac Surgery
Program Head: Dr Andrew Newcomb
The research team in this program is looking at new and innovative ways to improve outcomes of vascular and cardiac
surgery. It is particularly concerned with the outcomes from a patient perspective as well as developing efficient procedures.
Projects include:
• Clinical and QoL followup of radial artery harvest patients, comparing open and endoscopic harvesting
• Functional assessment of endoscopically harvested arteries compared to conventionally harvested radial arteries
• Cost of health care delivery
• Epidemiologically based outcomes research into high risk populations for cardiac surgery
• Heart failure and left ventricular leads placed at time of concomitant surgery
• Outcomes of aortic dissection using a hybrid approach
• Investigation of cardiotomy filtrate components
• Impact of use of different wound dressings on wound infection rates
• Impact of mini cardiopulmonary bypass circuit on inflammation and clinical outcomes
• Echocardiography Guided Cardiac Resynchronization Therapy Clinical Investigation (EchoCRT)
• Surgical Treatment for Ischemic Heart Failure Extension Study (STICHES) Trial
Researchers and students:
Ms Sophie Hofferberth. The role of insulin resistance in perioperative dysglycaemia, metabolic syndrome and
dysfunctional nitric oxide metabolism. BMedSci, University of Melbourne.
CvRC Annual Report 2010-2011
11
CvRC Programs (cont.)
5. Cardiac Services
Program Head: A/Prof Andrew MacIsaac
The research team in this program looks at clinical outcomes research, the pathophysiology of the pulmonary
circulation and interventional devices.
Projects include:
• Assessing early pulmonary hypertension in scleroderma
• Echocardiographic assessment left ventricular (LV) function
• Echocardiographic assessment of cardiac function in athletes
• Coronary physiology and interventional devices
6. Mental Health and Wellbeing
Program Head: Prof David Castle Deputy Head: A/Prof Karen-leigh Edward
Mental health and wellbeing has been found to impact strongly on the established risk factors of CVD. Reciprocally, a
cardiac event has adverse affects on the mental health and wellbeing of patients. The novel program of Collaborative
Therapy for the holistic treatment of people with mental illness, developed by Prof Castle and his colleagues, has been
widely acknowledged as a leading example of comprehensive consumer-oriented care, and has been adopted by
mental health services both within Victoria and nationally. This program within CvRC focuses on CVD related depression
in patients by looking at screening and referral mechanisms for cardiac patients as well as its interrelation with other risks
for CVD such as smoking and obesity.
Projects include:
• An audit of current screening and referral mechanisms towards the recognition and treatment for depression in
people with cardiac disease
• Being ‘fat’ in today’s world: A socio-cultural investigation of overweight and obesity
• An open trial of a (CBT)-based smoking cessation intervention plus varenicline intervention in people with a psychotic
disorder
• Improving the lifestyles of people with a psychotic illness
• An audit of metabolic monitoring in a mental health service
• A longitudinal study of cardiac echocardiograms in patients on clozapine
Researchers and students:
Dr Kate McGregor. Personality, schizophrenia, and violence. PhD, Monash University – completed 2010.
Dr Wei Lin Toh. Perceptual abnormalities and attentional biases in body dysmorphic disorder. PhD, University of
Melbourne – completed 2011.
Dr Carol Silberberg. Mental health and type I diabetes mellitus. DMedSci, University of Melbourne.
Dr Nicole Joshua. Investigating sex differences in emotional processing in schizophrenia patients and healthy
controls. PhD, University of Melbourne.
Ms Sue Lauder. Development and evaluation of an on-line programme for treating bipolar disorder. PhD, University
of Melbourne.
Dr James Le Bas. The Prestige Model and its application to bipolar disorder. PhD, University of Melbourne.
Mr Frank Perri. Psychological support in the cosmetic surgery process. PhD, Victoria University.
Ms Andrea Philipou. Anorexia nervosa: An fMRI study in visual scan pathways and saccadic eye movements. PhD,
University of Melbourne.
Dr Melissa Tang. The unique impact of bone and soft tissue sarcoma on mental health outcomes; Attitudes of nonorthopaedic cancer specialists on patients with bone metastases. PhD, University of Melbourne.
12
7. Psychosocial Research
Program Head: Prof David Thompson Co-Head: A/Prof Chantal Ski
The Psychosocial Research Program aims to provide patients, families and clinicians with the information and skills
necessary to improve cardiovascular health and wellbeing. The primary area of research pertains to psychosocial
interventions and outcome measurement, inclusive of behavioural and lifestyle change, in order to reduce the risk
of cardiovascular disease and burden.
Projects include:
• Psychosocial dimensions of CVD in indigenous populations and in disease management programmes for
individuals at high risk of cardiovascular disease
• Self-care and cognitive impairment in chronic heart failure
• Neurocognitive aspects of depression and CVD
Researchers and students:
Mr Sam Munian. Knowledge of depression as described by nurses on a cardiac unit. BN Honours, Australian Catholic
University – completed 2010.
Ms Jenni Hicks. Systematic review: Gender differences in 12-month outcomes of patients with primary percutaneous
coronary intervention after acute myocardial infarction. BN Honours, Australian Catholic University – completed 2011.
Mr Ronald Trejo. Medical records review; Efficacy of referral methods to secondary prevention programs of people with
atherosclerosis disease and their attendance. BN Honours, Australian Catholic University – completed 2010.
8. Basic CVD Science
Program Head: Prof Darren Kelly
This program aims to develop new strategies and treatment approaches to reduce the impact of chronic heart
failure. One approach this program takes is to address the development of new drugs for the effective prevention
of diabetic nephropathy as a risk reduction.
Projects include:
• Novel therapeutic strategies to reduce the burden of chronic heart failure
• Development of new anti-fibrotic drugs for prevention of diabetic nephropathy
• Prevention and treatment of chronic heart and kidney disease via epidemiological, pharmacological device and
cell based approaches
Researchers and students:
Ms Sih Min Tan. Novel therapies to inhibit pathological fibrosis associated with the pathogenesis of kidney and
heart failure. PhD, Department of Medicine, St Vincent’s Hospital, University of Melbourne – completed in 2011.
Ms Fay Khong. The potential effects of flavonoids in acute and chronic heart and kidney diseases, PhD, University
of Melbourne.
Ms Suree Lekawanvijit. Cardiorenal syndrome: Pathophysiology, role of protein-bound uraemic toxins. PhD,
Monash University.
Ms Christina Tan. Novel therapies for cardiac and renal disease. PhD, Department of Medicine, St Vincent’s
Hospital, University of Melbourne.
Mr Mark Waddingham. Assessing changes in glomerular structure with pirfenidone in experimental diabetic
nephropathy. BSc Honours, University of Melbourne.
Dr Michael Zhang. Fibrosis in experimental Diabetic Nephropathy and Cardiomyopathy: Effects of FT011, a novel
anti-fibrotic intervention? PhD, Department of Medicine, St Vincent’s Hospital, University of Melbourne.
CvRC Annual Report 2010-2011
13
CvRC Programs (cont.)
9. Heart Failure & Imaging
Program Head: A/Prof David Prior Deputy Head: Dr Peter Mossop
The Heart Failure and Imaging program focuses on the use of non-invasive cardiac imaging to understand both
physiological and pathological cardiac and pulmonary vascular function. Physiology is studied in athletes and pathology
is studied in subjects with heart failure, those at risk of heart failure and those at risk of pulmonary hypertension. In
some cases, the differentiation of normal physiologic changes and early pathologic changes can be difficult and
the researchers are focusing on the early identification of disease states in athletes through the use of screening
electrocardiograms (ECGs); in those at risk of heart failure through the use of blood tests, ECG and echocardiography,
and in those patients with scleroderma who are at risk of pulmonary hypertension through the use of echocardiography
during exercise or other forms of stress-testing. The program aims to identify disease states at an early stage where
treatment strategies are likely to be more effective in preventing death or disability.
Projects include:
• An audit of cardiac echocardiograms in patients on clozapine
• Echocardiography Guided Cardiac Resynchronization Therapy Clinical Investigation (EchoCRT) (ongoing)
• Surgical Treatment for Ischemic Heart Failure Extension Study (STICHES) Trial (ongoing)
• Assessing early pulmonary hypertension in scleroderma (ongoing)
• Effect of diabetes on the heart (ongoing)
• Assessment of early pulmonary arterial hypertension using dobutamine stress echocardiograms in patients with
scleroderma (ongoing)
• NT-proBNP and the identification and treatment of structural heart disease and heart failure in high-risk individuals
(ongoing)
• Cardiac structure and function in endurance athletes
• Screening for cardiac abnormalities in Australian athletes (ongoing)
• Effects of exercise training on cardiac structure and function in indigenous footballers (ongoing)
Researchers and students:
Dr Maria Brosnan. The effect of exercise training on cardiac structure, function and the electrocardiogram in
Indigenous and non-Indigenous elite Australian athletes. PhD, University of Melbourne.
Dr Jennifer Coller. Identifying early cardiac failure using novel echocardiographic techniques and serum NT-proBNP
levels. PhD, University of Melbourne.
14
CvRC Partnerships
CvRC is currently demonstrating its commitment to multi-partner research by collaborating across a wide range of
units within its three partners:
•
•
•
•
•
•
St Vincent’s Clinical/Cardiac Investigation Unit (St Vincent’s Hospital Melbourne)
The Department of Medicine (University of Melbourne)
St Vincent’s Institute (St Vincent’s Hospital Melbourne & University of Melbourne)
St Vincent’s Centre for Nursing Research (ACU & St Vincent’s Hospital Melbourne)
The O’Brien Institute of Microsurgery (St Vincent’s Hospital Melbourne, University of Melbourne & ACU)
The Immunology Research Centre (St Vincent’s Hospital Melbourne)
The Centre has also forged links with other local, national and international institutions:
Local and National Collaborations
International Collaborations
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Austin Health
Baker IDI Heart & Diabetes Institute
Curtin University
Deakin University
Monash University
Pacific Clinical Research Group
Royal Prince Alfred Hospital
The Heart Foundation
Stanford University Medical Center, USA
University of Alberta, Canada
University of California, USA
University of Kentucky, USA
University of Leicester, UK
University of Pennsylvania, USA
The Cardiovascular Research Centre and its partners are looking forward to some exciting outcomes from this
important research collaboration that will go beyond the three founding partners and provide excellent return-oninvestment for the collaborators’ and donors’ funds.
Community Engagement
CvRC has close ties with organisations such as the Heart
Foundation and Australian Unity. These organisations
have made it their goal to educate the public about risks
and prevention possibilities and regularly utilise CvRC
research results in this context.
In July 2011, CvRC launched its website (www.cvrc.edu.
au) which will also be a vehicle to update the public with
current research results, ongoing projects and offer people
interested in research a platform to access experienced
researchers. It is hoped that the work CvRC conducts
will influence evidence-based practice and educate the
community, in order to eventually decrease the risk of CVD.
The CvRC website.
CvRC Annual Report 2010-2011
15
Events & Highlights
CvRC Launch
CvRC has been operating as a “virtual centre” since August 2009. The physical establishment of the centre in the
VECCI Building in Albert Street, East Melbourne in August 2010 has provided a professional space for some of the
research teams. CvRC celebrated the launch of its new location in November 2010.
“The Australian Catholic University is at an important
moment in its development as a tertiary provider: to maintain
our achievements to this point or to envision a our greater
role in the Australian education sector. The Cardiovascular
Research Centre symbolises ACU’s commitment to the
latter. It enhances our proud connection with St Vincent’s
Hospital, developed over many years and a more recent
partnership with the University of Melbourne, a university
of international pre-eminence.”
– Prof Greg Craven, ACU Vice-Chancellor
“An enormous effort was expended by Rob, Linda and
the team in developing this Centre. It will form a model
St Vincent’s would like to adopt for other key research
groups, particularly as benefits go across many disciplines
and bring together researchers, scientists and clinicians.”
– Prof Richard Fox, St Vincent’s Director of Research
16
“The CvRC is a natural fit to the clinical partnerships ACU
has endeavoured to develop with leading healthcare
institutions, such as St Vincent’s, who has an enviable and
well deserved reputation for innovation and excellence in
healthcare. The Faculty of Health Sciences is proud to be
associated with this endeavour and wish to congratulate
the two primary drivers of this venture.”
– Prof Pauline Nugent, ACU Executive Dean of Health Sciences, now Deputy Vice-Chancellor (Academic)
(L–R) Adj Prof Cynthia Dowell, Mr John Gurry, Prof
Whitbourn, Prof Nugent, Prof Worrall-Carter, Prof
Martin, Prof Greg Craven, Prof Campbell & Prof
Thompson.
(L–R) Prof Castle, Prof Worrall-Carter, A/Prof Page,
A/Prof Ski, Prof Whitbourn, Prof Thompson & A/Prof
Michael Salzberg.
CvRC Annual Report 2010-2011
17
Events & Highlights (cont.)
Australia & New Zealand Optical Coherence Tomography (ANZ OCT) Workshop
Around 100 specialists, researchers, nursing and technical staff from
across Australia and New Zealand attended the inaugural Australia &
New Zealand Optical Coherence Tomography (ANZ OCT) Workshop.
The event, which was founded by Dr Peter Barlis (Northern Hospital)
and Prof Whitbourn, was held in Melbourne at the Park Hyatt’s Ballroom on the May 7, 2010.
The workshop explored the use of optical coherence tomography (OCT),
highly detailed coronary imaging equipment, particularly in the diagnosis
and management of patients with heart disease.
The guest faculty comprised internationally renowned clinicians and scientists, including Dr Dougal McClean (Christchurch Hospital), Professor
Ian Meredith (Monash Heart), Professor John Ormiston (Auckland City
Hospital), Dr Chris Raffel (Prince Charles Hospital), Professor Darren
Walters (Prince Charles Hospital), Professor Stephen Worthley (Royal
Adelaide Hospital) and Dr Shaosong Zhang (LightLab Imaging).
Prof Whitbourn said there was a void in information about novel intracoronary imaging technologies across Australia and New Zealand and
so the workshop had been an “ideal forum” to bring together clinicians
and researchers interested in studying the technology.
Dr Barlis and Prof
Whitbourn welcomed
almost 100 attendees
to the inaugural ANZ
OCT Workshop,
which looked at
optical coherence
tomography (right).
18
ANZ OCT Workshop conveyors
Dr Barlis and Prof Whitbourn.
Awards
Dr La Gerche received the Cardiac Society of Australia and
New Zealand’s Ralph Reader Prize in 2010 (Clinical Science Section) for “Intense prolonged exercise (IPE) causes
acute right ventricular (RV) injury which may not always be
completely reversible”.
A/Prof Wilson was awarded the Sylvia & Charles Viertel
Charitable Foundation’s Clinical Research Fellowship
in 2010 to assist his research into adipocyte, biology, insulin
resistance and cardiovascular diseaese.
Dr La Gerche
Dr Layland was the Fellows’ Prize Winner at the 2010 Australia and New Zealand Endovascular Therapies (ANZET)
Meeting.
Dr Layland also received the University of Melbourne’s
cardiovascular research grant for 2010/2011.
Dr La Gerche was also the recipient of an NHMRC
postdoctoral training fellowship in the overseas-based
clinical category for 2011–2014.
A/Prof Edward, along with co-editors Ian Munro, Alan Robins & Anthony Welch, won the Australian Publishers Association Australian Educational Publishing Awards
2011 in the Tertiary (Wholly Australian) Teaching & Learning
Category, for their book Mental Health Nursing – Dimensions of Praxis.
Prof Castle
Dr Jan Cameron, Ms Meriem Perona, A/Prof Ski and Prof
Thompson won the Best Poster Award for “Development
of an assessment tool specific for chronic heart failure patient self-care ability” at the Victorian Association of Cardiac
Rehabilitation State Conference in October 2011.
Prof Castle was presented with the 2011 MSD Senior
Research Award by the Royal Australian and New Zealand
College of Psychiatrists (RANZCP). The award is given to
the Fellow who has made the most significant contribution
to psychiatric research in Australia and New Zealand over
the preceding five years.
Ms Rhonda Sanders was awarded the 2010 Heart
Foundation President’s Award in appreciation of her
significant contribution to the Foundation’s work.
Ms Rhonda Sanders (left) receiving her award from
Professor Jennifer Johns
CvRC Annual Report 2010-2011
19
Media Coverage
Print
“Aussie experts lead global trial in heart disease”. Herald Sun. May
24, 2011. http://www.heraldsun.com.au/news/aussie-experts-leadglobal-trial-in-heart-disease/story-e6frf7jo-1226061490198
Prof Whitbourn as part of the team who is leading the first human
trials of a treatment for heart disease involving dissolvable stents
placed in patients’ hearts.
Whitelocks, Sadie. “Running marathons ‘could permanently damage
the heart’”. Daily Mail. December 7, 2011. http://www.dailymail.co.uk/
health/article-2071018/Running-marathons-permanently-damageheart.html
Dr La Gerche interviewed about his study, which found that highendurance activities can lead to scarring of the right ventricle of the
heart, increasing the risk of health complications.
Online
“Hypertension eliminated with funding hope”. DPS Guide to Aged Care. July 4, 2011. http://www.agedcareguide.
com.au/news.asp?newsid=6146
“Inaugural Australia & New Zealand Optical Coherence Tomography Workshop a Success!” OCT News. May 8,
2010. http://www.octnews.org/articles/2018905/inaugural-australia-new-zealand-optical-coherence
“REVA to conduct plastic stent trials”. Ninemsn News. May 23, 2011. http://news.ninemsn.com.au/article.
aspx?id=8252630
van den Berg, Lucie. “Lazy women warned of disease”. Herald Sun. August 11, 2011. http://www.heraldsun.com.
au/news/more-news/lazy-women-warned-of-disease/story-fn7x8me2-1226112667117
20
Television
Ha, Tanya. “Exercise overdose”. Catalyst, Australian Broadcasting Corporation. Broadcast February 24, 2011.
Online at: http://www.abc.net.au/catalyst/stories/3147421.htm
Dr La Gerche interviewed about his research, which suggests that extreme levels of exercise may damage the
heart.
Whitehead, Lisa. “New treatment for hypertension”. 7.30, Australian Broadcasting Corporation. Broadcast June 30,
2011. Online at: http://www.abc.net.au/7.30/content/2011/s3258048.htm
Prof Whitbourn interviewed about the world-first trial for renal denervation and the need for further funding.
CvRC Annual Report 2010-2011
21
Research Outcomes
Over the past years, staff members from ACU, St Vincent’s and the University of Melbourne have engaged in
several successful research collaborations, demonstrating the ability of this group to operate as a partnership.
Since the formal establishment of CvRC, staff has attracted over 20 CvRC-led grants totalling $2.3 million and has
been involved in a further 17 collaborative grants worth an additional $8.5 million. CvRC researchers have also
published over 190 journal articles and held several hundred presentations. This is not only helping to increase
the public’s knowledge about CVD and its risk factors but is also impacting positively on the reputation of the
partner institutions in this chosen field of research, creating a competitive advantage towards other institutions
within Australia and beyond.
Grants
2011
Berk, M., Jacka, F., Castle, D., Brazionis, L. & Itsiopoulos, C. (2011). Diet as a therapeutic target in depression: A
randomised controlled trial. National Health and Medical Research Council. $481,810.
Berk, M., Suppes, T. & Castle, D. (2011). A randomised trial of internet-based interventions for bipolar disorder. National
Institute of Mental Health. US$436,613.
Brown, A., Carrington, M., Eades, S., Thompson, D.R. & Zeitz, C. (2011-2015). The central Australian heart protection
study: A randomised trial of nurse-led, family based secondary prevention of acute coronary syndromes. NHMRC.
$1,830,401.
Cameron, J., Ski, C.F. & Thompson, D.R. (2010). A Delphi study to quantify self-care skills using the INCOGNITO
screening tool. CvRC: Faculty (Health Sciences) Research Grant, Australian Catholic University. $14,838.
Cameron, J., Thompson, D.R. & Ski, C.F. (2011-2013). Evaluating an assessment tool to guide heart failure self-care
education. NBV Mona Menzies Postdoctoral Research Grant. $49,105.
Castle, D. (2011). Medication Information Project. Janssen Cilag (investigator initiated study). $6,000.
Castle, D. & Piterman, L. (2011). Difficult To Treat Depression. Astra Zeneca (investigator initiated study). $268,000. Choong, P., Castle, D., Salzberg, M., Dowsey, M., Knowles, S. & Monshat, K. (2011). Mindfulness and coping in chronic
illness: insights from a study of joint replacement surgery. Australian Research Council. $270,445.
Couper, J., Pollard, A. & Castle, D. (2011). A mindfulness intervention for depression and anxiety in head and neck
cancer. beyondblue. $150,000.
Newcomb, A.E., Hofferberth, S.C., Yii, M.Y., Wilson, A.M. (2011). Dysglycaemia in Cardiac Surgery. St Vincent’s Hospital
Research Endowment Fund. $15,000.
Page, K., Wilson, A., Worrall-Carter, L., Castle, D., Thompson, D.R. & Whitbourn, R. (2011). A secondary prevention
patient-centred model for smoking cessation. St Vincent’s Research Endowment Fund. $27,381.
Rolley, J. X., Worrall-Carter, L., Page, K. & Whitbourn, R. (2011). Delivering best practice nursing in the cardiac
catheterisation laboratory environment through the development of practice standards, competencies and clinical
practice guidelines. ACU Faculty of Health Sciences 2011 Research Grant. $15,000.
Stewart, S., Thompson, D.R., Abhayaratna, W., Marwick, T., Carrington, M., Gould, P., Kostner, K., Inglis, S., Schuffham,
P., Haluska, B & Ski C.F. (2011-2015). Integration of risk evaluation in cardiovascular disease management
programs. NHMRC. $3,200,000.
Worrall-Carter, L., Page, K., Thompson, D., Ski, C., Castle, D., Whitbourn, R., Salzberg, M. & Wilson, A. (2011-2013).
Managing depression and anxiety risk in those with cardiovascular disease: A nurse-led intervention. beyondblue.
$120,760.
2010
Baker, A., Richmond, R. & Castle, D. (2010). Improving the lifestyles of people with a psychotic illness: A follow-up study.
National Health and Medical Research Council, Project Grant. $430,000
Cameron, J., Ski, C., Thompson, D.R., Whitbourn, R. & Henderson, J. (2010). Development of a patient risk assessment
tool for self-managing heart failure symptoms. St Vincent’s Research Endowment Fund. $15,000.
Campbell, D., Prior, D. & Black, M.J. (2009-2010). Effect of diabetes on the heart. National Heart Foundation of Australia.
$65,000.
Campbell, D., Prior, D. & Black, M.J. (2009-2010). Effect of diabetes on the heart. National Heart Foundation of Australia.
$129,000.
Campbell, D., Prior, D., Liew, D. & Wolffe, R. (2009-2013). NT-proBNP and the identification and treatment of structural
heart disease and heart failure in high-risk individuals. National Health and Medical Research Council, Project grant.
$1,420,375.
22
Castle, D.J., Newton, R. & Bosanac, P. (2010). A regional Body Image and Eating Disorders Programme. Department of
Health, Victoria. $1,200,000.
Couper, J., Pollard, A., Corry, J., Boonzaier, A., Smith, D. & Castle, D. (2010). An investigation of levels of psychological
distress (depression and anxiety) and unmet needs amongst people diagnosed with head and neck cancer: A
follow-up study. beyondblue. $28,000.
Dowsey, M., Choong, P. & Castle, D. (2010). Examining the prevalence of preoperative psychological distress in patients
presenting for primary lower limb joint replacement. St Vincent’s Hospital Research Endowment Fund. $14,585.
Hill, N., Joubert, L., Hawthorne, G. & Castle, D. (2010). Suicide prevention in the emergency department (SPED). St
Vincent’s Hospital Research Endowment Fund. $8,413.
Knowles, S., Kamm, M., Salzberg, M.R., Castle, D., Connell, W.F. & Bell, S. (2010). IBDe Therapy: Development and
validation of the world’s first evidence-based, automated online programme for the assessment and treatment of
IBD-associated anxiety and depression. BROAD Foundation (USA). AU$78,915.
Love, A., Richardson, C., Halpin, P., Smith, J., Bosanac, P., Petrakis. M., Castle, D.J., Scanlon, A. & Organ, B.A. (2010).
Seeing the difference it makes: Building a recovery based culture in a clinical mental health service. Department of
Health, Victoria. $30,000.
Newcomb, A. (2010). Nitrix Oxide Metabolism, Cardiovascular Disease and Myocardial Injury. ASCTS Foundation grant.
$10,000.
Newcomb, A.E., Hofferberth, S.C., Yii, M.Y., Wilson, A.M. (2010). Dysglycaemia in Cardiac Surgery. Australasian Society
of Cardiothoracic Surgeons Research Foundation grant. $10,000.
Page, K., Worrall-Carter, L., Edward, K. & Wilson, A. (2009-2010). Nurse-led (CVD) Risk Intervention Screening Clinic
(NL-RISC). Nurses Board of Victoria, Ella Lowe grant. $49,877.
Piterman, L. & Castle, D. (2010). Difficult to treat depression. Astra Zeneca. $150,000.
Piterman, L. & Castle, D. (2010). Treating bipolar disorder. Astra Zeneca (investigator initiated grant). $150,000
Prior, D., Stevens, W. & MacIsaac, A. (2010). Assessment of early pulmonary arterial hypertension using dobutamine
stress echocardiograms in patients with scleroderma. National Heart Foundation of Australia. $55,000.
Whitbourn, R. (2010). Absorb Extend study (BioAbsorbable stent). Abbott Vascular Inc. $50,000.
Whitbourn, R. (2010). Evolve Study. Boston Scientific Inc. $35,000.
Wilson, A., Worrall-Carter, L., Page, K., Castle, D., Salzberg, M., Liew, D., Brock, K., Martin, A., Gilbert, M., Whitbourn,
R., Weiland, T., Matthews, S., Doyle, L., Langham, R., Smith, P. & Gonzales, G. (2010). Cardiovascular Disease
Secondary Prevention Consortium. St Vincent’s Hospital Research Endowment Fund. $15,000.
Wilson, A., Worrall-Carter, L., Page, K., Whitbourn, R., Cook, M., Liew, D., Martin, A., O’Neal, D., Campbell, C. &
Gonzales, G. (2010-2011). An innovative patient centred care model for secondary prevention vascular disease.
Sanofi-Aventis. $70,000.
Worrall-Carter, L., Davidson, P., Whitbourn, R., Macdonald, P., Castle, D., Page, K., Cummins, R., Wilson, A., Salzberg,
M., Hamilton, B., Edward, K., Gilbert, M. & Thompson, D. (2009-2010). An audit of current screening and referral
mechanisms towards the recognition and treatment for depression in people with cardiac disease. St Vincent’s
Hospital Research Endowment Fund. $14,000.
Worrall-Carter, L., Jelinek, G., Page, K., Swift, R., Kuhn, L., & Ski, C. (2010). Optimising Early Assessment and Outcomes
in Acute Coronary Syndrome. ACU, Faculty Research Grant. $15,000.
Worrall-Carter, L., Page, K., Edward, K., Campbell, M., Whitbourn, R., Liew, D. & Davidson, P. (2009-2011). Profiling
Australian Women at Risk of Cardiovascular Disease (PAWaR study). ACU Faculty grant. $15,000.
Worrall-Carter, L., Page, K., Rolley, J., Thompson, S., Daws, K., Leishman, M., McCarthy, S., Whitbourn, R. &
MacIsaac, A. (2010-2012). Delivering best practice and education for the contemporary cardiac catheter laboratory
environment. Medtronic/ACU Faculty grant. $160,000.
CvRC Annual Report 2010-2011
23
Book Chapters
2011
Martin, C. R., Fleming, M. & Thompson, D.R. (2011). Coronary heart disease, diet and neurocognitive functioning. In: Handbook
of Behaviour, Food and Nutrition. (Eds: Preedy, V.R., Watson, R.R. & Martin, C.R.), London: Springer, 1555-1566.
Webster, R.A. & Thompson, D.R. (2011). Nursing Patients with cardiovascular disorders. In: Alexander’s Nursing Practice
4th Edition. (Eds: Brooker, C. & Nicol, M.), Edinburgh: Churchill Livingstone, 9-50.
2010
Thompson, D.R. & Martin, C.R. (2010). Measurement issues in the assessment of quality of life in patients with coronary
heart disease. In: Handbook of Disease Burdens and Quality of Life Measures. (Eds: Preedy, V.R., Watson, R.R.
& Martin, C.R.), London: Springer, 2983-98.
Publications
2011
ACTIVE I Investigators (Whitbourn, R.), Yusuf, S., Healey, J.S., Pogue, J., Chrolavicius, S., Flather, M., Hart, R.G.,
Hohnloser, S.H., Joyner, C.D., Pfeffer, M.A. & Connolly, S.J. (2011). Irbesartan in patients with atrial fibrillation. The
New England Journal of Medicine, 364(10):928-938.
Berben, L., Bogert, L., Leventhal, M.E., Fridlund, B., Jaarsma, T., Norekval, T.M., Smith, K., Stromberg, A., Thompson, D.R.
& De Geest, S. (2011). Which interventions are used by health care professionals to enhance medication adherence in
cardiovascular patients? A survey of current clinical practice. European Journal of Cardiovascular Nursing, 10(1):14-21.
Berkelmans, A., Burton, D., Page, K. & Worrall-Carter, L. (2011). Registered nurses’ smoking behaviours and their
attitudes to personal cessation. Journal of Advanced Nursing, 67(7):1580-1590.
Blair, J., Corrigall, H., Angus, N., Thompson, D.R. & Leslie, S.J. (2011). Home versus hospital-based cardiac rehabilitation:
A systematic review. Remote Rural Health, 11:153.
Boyde, M., Turner, C., Thompson, D.R. & Stewart, S. (2011). Educational interventions for patients with heart failure: A
systematic review of randomised controlled trials. Journal of Cardiovascular Nursing, 26(4):E27-E35.
Boyle, A.J., Yeghiazarians, Y., Shih, H., Hwang, J., Ye, J., Sievers, R., Zheng, D., Palasubramaniam, J., Palasubramaniam,
D., Karschimkus, C., Whitbourn, R., Jenkins, A. & Wilson, A.M. (2011). Myocardial production and release of MCP-1
and SDF-1 following myocardial infarction: Differences between mice and man. Journal of Translational Medicine, 9:150.
Brugaletta, S., Gomez-Lara, J., Serruys, P.W., Farooq, V., Van Geuns, R.J., Thuesen, L., Dudek, D., Koolen, J., Chevalier,
B., McClean, D., Windecker, S., Smits, P.C., De Bruyne, B., Whitbourn, R., Meredith, I., Van Domburg, R.T., Sihan,
K., De Winter, S., Veldhof, S., Miquel-Hebert, K., Rapoza, R., Garcia-Garcia, H.M., Ormiston, J.A. & Bruining,
N. (2011). Serial in vivo intravascular ultrasound-based echogenicity changes of everolimus-eluting bioresorbable
vascular scaffold during the first 12 months after implantation insights from the ABSORB B trial. JACC-Cardiovascular
Intervention, 4(12):1281-1289.
Brugaletta, S., Garcia-Garcia, H.M., Diletti, R., Gomez-Lara, J., Garg, S., Onuma, Y., Shin, E.S., Van Geuns, R.J., De Bruyne,
B., Dudek, D., Thuesen, L., Chevalier, B., McClean, D., Windecker, S., Whitbourn, R., Dorange, C., Veldhof, S., Rapoza,
R., Sudhir, K., Bruining, N., Ormiston, J.A. & Serruys, P.W. (2011). Comparison between the first and second generation
bioresorbable vascular scaffolds: a six month virtual histology study. EuroIntervention, 6(9):1110-1116.
Brugaletta, S., Garcia-Garcia, H.M., Garg, S., Gomez-Lara, J., Diletti, R., Onuma, Y., Van Geuns, R.J., McClean, D.,
Dudek, D., Thuesen, L., Chevalier, B., Windecker, S., Whitbourn, R., Dorange, C., Miquel-Hebert, K., Sudhir, K.,
Ormiston, J.A. & Serruys, P.W. (2011). Temporal changes of coronary artery plaque located behind the struts of the
everolimus eluting bioresorbable vascular scaffold. International Journal of Cardiovascular Imaging, 27(6):859-866.
Brugaletta, S., Gomez-Lara, J., Diletti, R., Farooq, V., Radu, M., Van Geuns, R-J., De Bruyne, B., Dudek, D., Thuesen,
L., Chevalier, B., McClean, D., Windecker, S., Whitbourn, R., Dorange, C., Li, D., Veldhof, S., Onuma, Y., Bruining,
N., Garcia-Garcia, H.M., Ormiston, J.A. & Serruys, P.W. (2011). Comparison of in vivo eccentricity and symmetry
indices between metallic stents and bioresorbable vascular scaffolds: Insights from the absorb and spirit trials.
Journal of the American College of Cardiology, 57(14):E1700.
Cameron, J., Ski, C.F. & Thompson, D.R. (2011). Cognitive impairment in chronic heart failure and the need for
screening. American Journal of Cardiology, 107(10):1547-1548.
Chau, J. P.C., Thompson, D. R., Twinn, S., Lee, D. T. & Pang, S. W. (2011), An evaluation of hospital hand hygiene
practice and glove use in Hong Kong. Journal of Clinical Nursing, 20(9-10):1319–1328.
24
Chau, J.P.C., Lo, S.H.S., Thompson, D.R., Fernandez, R. & Griffiths, R. (2011). Use of end-tidal carbon dioxide detection to
determine correct placement of nasogastric tube: A meta-analysis. International Journal of Nursing Studies, 48(4):513-21.
Cheng, K.K.F., Lee, J., Leung, S.F., Liang, R.H., Tai, J.W., Yeung, R.M. & Thompson, D.R. (2011). Use of Rasch analysis
in the evaluation of the Oropharyngeal Mucositis Quality of Life Scale. Journal of Nursing Research, 60(4):256-63.
Cheng, K.K.F., Lee, V., Li, R., Goggins, W., Thompson, D.R., Yuen, H.L. & Epstein, J. (2011). Incidence and risk factors
of oral mucositis in paediatric and adolescent patients undergoing chemotherapy. Oral Oncology, 47(3):153-62.
Clark, A.M., Jaarsma, T., Strachan, P., Davidson, P.M., Jerke, M., Beattie, J.M., Duncan, A.S., Ski, C.F. & Thompson, D.R.
(2011). Effective communication and ethical consent in decisions related to ICDs. Nature Reviews Cardiology, 8:694-705.
Conway, A., Page, K., Rolley, J. & Worrall-Carter, L. (2011). Nurse-administered procedural sedation and analgesia: An
integrative review. International Journal of Nursing Studies, 48(8):1012-1023.
Copple, S.S., Sawitzke, A.D., Wilson, A.M., Tebo, A.E. & Hill, H.R. (2011). Enzyme-linked immunosorbent assay screening
then indirect immunofluorescence confirmation of antinuclear antibodies: A statistical analysis. American Journal of
Clinical Pathology, 135(5):678-684.
Davidson, P.M., Daly, J., Leung, D., Ang, E., Paull, G., Digiacomo, M., Hancock, K., Cao, Y., Du, H. & Thompson,
D.R. (2011). Health-seeking beliefs of cardiovascular patients: A qualitative study. International Journal of Nursing
Studies, 48(11):1367-1375.
Dickson, V. V., Worrall-Carter, L., Kuhn, L. & Riegel, B. (2011). Whose job is it? Gender differences in perceived role in
heart failure self-care. Journal of Nursing and Healthcare of Chronic Illness, 3:99-108.
Diletti, R., Onuma, Y., Farooq, V., Gomez-Lara, J., Brugaletta, S., Van Geuns, R.J., Regar, E., De Bruyne, B., Dudek,
D., Thuesen, L., Chevalier, B., McClean, D., Windecker, S., Whitbourn, R., Smits, P., Koolen, J., Meredith, I., Li,
D., Veldhof, S., Rapoza, R., Garcia-Garcia, H.M., Ormiston, J.A. & Serruys, P.W. (2011). 6-Month clinical outcomes
following implantation of the bioresorbable everolimus-eluting vascular scaffold in vessels smaller or larger than
2.5mm. Journal of the American College of Cardiology, 58(3):258-264.
Driscoll, A., Tonkin, A., Worrall-Carter, L., Riegel, B., Hare, D., Davidson, P., Mulvaney, C. & Stewart, S. (2011).
Development of an evidence-based scoring system (HF-IS) to assess the quality of heart failure programs for
patients postdischarge from hospital. Journal of Clinical Nursing, 20(21-22):3011-3019.
Driscoll, A., Worrall-Carter, L., Hare, D.L. , Davidson, P.M., Riegel, B., Tonkin, A. & Stewart, S. (2011). Evidence-based
chronic heart-failure management programmes: Reality or myth? BMJ Quality and Safety, 20(1):31-37.
Edward, K., & Welch, A. (2011). The extension of Colaizzi’s method of phenomenological enquiry. Contemporary Nurse.
39(2):164-72.
Elliott, M., Crookes, P., Worrall-Carter, L. & Page, K. (2011). Re-admission to intensive care: A qualitative analysis of
nurses’ perceptions and experiences. Heart & Lung: the Journal of Acute and Critical Care, 40(4):299-309.
Fernandez, R., Chau, J.P.C., Thompson, D.R. & Griffiths, R. (2011). Accuracy of biochemical markers for predicting nasogastric
tube placement – A systematic review of diagnostic studies. International Journal of Nursing Studies, 47(8):1037-1046.
Gomez-Lara, J., Brugaletta, S., Diletti, R., Garg, S., Onuma, Y., Gogas, B.D., Van Geuns, R.J., Dorange, C., Veldhof, S.,
Rapoza, R., Whitbourn, R., Windecker, S., Garcia-Garcia, H.M., Regar, E. & Serruys, P.W. (2011). A comparative
assessment by optical coherence tomography of the performance of the first and second generation of the
everolimus-eluting bioresorbable vascular scaffolds. European Heart Journal, 32(3):294-304.
Gomez-Lara, J., Brugaletta, S., Farooq, V., Onuma, Y., Diletti, R., Windecker, S., Thuesen, L., McClean, D., Koolen, J., Whitbourn,
R., Dudek, D., Smits, P.C., Chevalier, B., Regar, E., Veldhof, S., Rapoza, R., Ormiston, J.A., Garcia-Garcia, H.M. & Serruys,
P.W. (2011). Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting
scaffolds using optical coherence tomography. JACC-Cardiovascular Intervention, 4(12):1271-1280.
Gomez-Lara, J., Brugaletta, S., Farooq, V., Van Geuns, R.J., De Bruyne, B., Windecker, S., McClean, D., Thuesen, L., Dudek,
D., Koolen, J., Whitbourn, R., Smits, P.C., Chevalier, B., Morel, M.A., Dorange, C., Veldhof, S., Rapoza, R., Garcia-Garcia,
H.M., Ormiston, J.A. & Serruys, P.W. (2011). Angiographic geometric changes of the lumen arterial wall after bioresorbable
vascular scaffolds and metallic platform stents at 1-year follow-up. JACC: Cardiovascular Interventions, 4(7):789-799.
Gomez-Lara, J., Radu, M., Brugaletta, S., Farooq, V., Diletti, R., Onuma, Y., Windecker, S., Thuesen, L., McClean, D., Koolen,
J., Whitbourn, R., Dudek, D., Smits, P.C., Regar, E., Veldhof, S., Rapoza, R., Ormiston, J.A., Garcia-Garcia, H.M. &
Serruys, P.W. (2011). Serial analysis of the malapposed and uncovered struts of the new generation of everolimus-eluting
bioresorbable scaffold with optical coherence tomography. JACC: Cardiovascular Interventions, 4(9):992-1001.
Gomez-Lara, J., Radu, M.D., Brugaletta, S., Farooq, V., Diletti, R., Windecker, S., Whitbourn, R., Dudeck, D., Smits, P.C., Regar,
E., Garcia-Garcia, H.M. & Serruys, P. (2011). Serial analysis of the malapposed and uncovered struts of the new generation
of everolimus-eluting bioresorbable scaffold using optical coherence tomography. Journal of the American College of
Cardiology, 57(14):E1680.
Heran, B.S., Chen, J.M.H., Ebrahim, S., Moxham, T., Oldridge, N., Rees, K., Thompson, D.R. & Taylor, R.S. (2011). Exercisebased cardiac rehabilitation for coronary heart disease. Cochrane Collaborative, 7:CD001800.
CvRC Annual Report 2010-2011
25
Publications 2011 (cont.)
Jelinek, M., Clark, A.M., Oldridge, N.B., Briffa, T.G. & Thompson, D.R. (2011). Reconciling systematic reviews of
exercised-based cardiac rehabilitation and secondary prevention programmes for coronary heart disease. European
Journal of Cardiovascular Rehabilitation and Prevention, 18(2):147-9.
Krum, H., Schlaich, M., Whitbourn, R., Sobotka, P.A., Sadowski, J., Bartus, K., Kapelak, B., Walton, A., Sievert, H.,
Thambar, S., Abraham, W.T. & Esler, M. (2011). Catheter-based renal sympathetic denervation for resistant
hypertension durability of blood pressure reduction out to 24 months. Hypertension, 57(5):911-917.
Kuhn, L., Page, K., Davidson, P. & Worrall-Carter, L. (2011). Triaging women with acute coronary syndrome: A review of
the literature. Journal of Cardiovascular Nursing, 26(5):395-407.
Layland, J., Burns, A.T., Somaratne, J. & Whitbourn, R.J. (2011). Looks can be deceiving: Dissociation between
angiographic severity and hemodynamic significance of a lesion: The importance of microvascular resistance.
Cardiovascular Revascularization Medicine, 12(4):258-261.
Layland, J., MacIsaac, A.M., Burns, A.T., Whitbourn, R.J. & Wilson, A.M. (2011). Integrated coronary physiology in
percutaneous intervention: A new paradigm in interventional cardiology. Heart Lung Circulation, 20(10):641-646.
Layland, J., Wilson, A.M., Lim, I. & Whitbourn, R.J. (2011). Virtual histology: A window to the heart of atherosclerosis.
Heart Lung and Circulation, 20(10):615-621.
Layland, J., Wilson, A., Whitbourn, R. & MacIsaac, A. (2011). Letter by Layland et al regarding article, “Validation
of intravascular ultrasound-derived parameters with fractional flow reserve for assessment of coronary stenosis
severity”. Circulation: Cardiovascular Interventions, 4(3):e16.
McCann, A.B., Taylor, J.H. & Whitbourn, R.J. (2011). Dual visualization: A technique to simplify native vessel intervention
in patients with bypass grafts. International Journal of Cardiology, 47(1):E10-E12.
Meredith, I.T., Whitbourn, R., Scott, D., El-Jack, S., Zambahari, R., Stone, G.W., Teirstein, P.S., Starzyk, R.M., Allocco,
D.J. & Dawkins, K.D. (2011). PLATINUM QCA: A prospective, multicentre study assessing clinical, angiographic,
and intravascular ultrasound outcomes with the novel platinum chromium thin-strut PROMUS Element everolimuseluting stent in de nova coronary stenoses. Eurointervention, 7(1):84-90.
Meredith, I.T., Worthley, S., Whitbourn, R., Webster, M., Fitzgerald, P.J. & Ormiston, J. (2011). First-in-human experience
with the Medtronic Bifurcation Stent System. EuroIntervention, 7(6):662-669.
Moser, D., Frazier, S., Worrall-Carter, L., Biddle, M., Chung, M., Lee, K. & Lennie, T. (2011). Symptom variability, not
severity, predicts rehospitalization and mortality in patients with heart failure. European Journal of Cardiovascular
Nursing, 10(2):124-129.
Norton, R., Sexton, D.W., Clark, I.M., Wilson, A.M., Hughes, D.A. & O’Connell, M.A. (2011). Immunomodulatory effects
of 1,25(OH)(2)D(3) in normal and transformed human lung epithelium. Anticancer Research, 31(4):1499-1499.
Onuma, Y., Radu, M., Okamura, T., Garcia-Garcia, H.M., Regar, E., Koolen, J., Thuesen, L., Windecker, S., Whitbourn,
R., McClean, D., Ormiston, J.A. & Serruys, P.W. (2011). Fate of side branches at 6 and 12 months after implantation
of bioresorbable vascular scaffolding devices: Assessment with 3-dimensional optical coherence tomography.
Journal of the American College of Cardiology, 57(14):E1659.
Onuma, Y., Serruys, P.W., Gomez, J., De Bruyne, B., Dudek, D., Thuesen, L., Smits, P., Chevalier, B., McClean, D., Koolen,
J., Windecker, S., Whitbourn, R., Meredith, I., Garcia-Garcia, H. & Ormiston, J.A. (2011). Comparison of In Vivo Acute
Stent Recoil Between the Bioresorbable Everolimus-Eluting Coronary Scaffolds (Revision 1.0 and 1.1) and the Metallic
Everolimus-Eluting Stent. Catheterization and Cardiovascular Interventions, 78(1):3-12.
Ramsay, C.F., Pearson, D., Mildenhall, S. & Wilson, A.M. (2011). Oral montelukast in acute asthma exacerbations: A
randomised, double-blind, placebo-controlled trial. Thorax, 66(1):7-11.
Riegel, B., Lee, C. S., Lennie, T., Moser, D., Bentley, B., Worrall-Carter, L., Chung, M., Heo, S., Eun Kyeung, S. & Albert,
N. (2011). From novice to expert: Confidence and activity status determine heart failure self-care performance.
Nursing Research, 60(2):132-138.
Savard, L.A., Thompson, D.R. & Clark, A.M. (2011). A meta-review of evidence on heart failure disease management
programs: The challenges of describing and synthesizing evidence on complex interventions. Trials, 12:194.
Schlaich, M.P., Esler, M.D., Walton, A., Whitbourn, R., Thambar, S., Sobotka, P.A. & Krum, H. (2011). Long term effect of
renal denervation on blood pressure in patients with resistant hypertension. Hypertension, 58(1):115.
Serruys, P.W., Onuma, Y., Dudek, D., Smits, P.C., Koolen, J., Chevalier, B., De Bruyne, B., Thuesen, L., McClean, D., Van
Geuns, R.J., Windecker, S., Whitbourn, R., Meredith, I., Dorange, C., Veldhof, S., Hebert, K.M., Sudhir, K., GarciaGarcia, H.M. & Ormiston, J.A. (2011). Evaluation of the second generation of a bioresorbable everolimus-eluting
vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes.
Journal of the American College of Cardiology, 58(15):1578-1588.
Shields, L., Watson, R. & Thompson, D. (2011). Editorial: Nursing education in the United Kingdom – Clocks forward or
clocks backward? Journal of Clinical Nursing, 20(15-16):2095–2097.
Ski, C.F. & Thompson, D.R. (2011). Beyond the blues: The need for integrated care pathways. European Journal of
Cardiovascular Prevention & Rehabilitation, 18(2):218-221.
26
Ski, C.F. & Thompson, D.R. (2011). Cardiac Rehabilitation in multicultural populations. International Journal of Cardiology,
148(2):129-30.
Ski, C.F. & Thompson, D.R. (2011). Cardiovascular nursing research: Challenges and opportunities. European Journal
of Cardiovascular Nursing, 10(1):1-2.
Ski, C.F. & Thompson, D.R. (2011). Commentary on Galdas, P.M. & Kang, H.B.K. (2010). Punjabi Sikh patients’ cardiac
rehabilitation experiences following myocardial infarction: A qualitative analysis. Journal of Clinical Nursing 19,
3134–3142. Journal of Clinical Nursing, 20:1210–1211.
Ski, C.F. & Thompson, D.R. (2011). Commentary on Yohannes, A.M., Doherty, P., Bundy, C. & Yalfani, A. (2010). The
long-term benefits of cardiac rehabilitation on depression, anxiety, physical activity and quality of life. Journal of
Clinical Nursing, 19: 2806–2813. Journal of Clinical Nursing, 20:1208–1209.
Ski, C.F. & Thompson, D.R. (2011). Online health communication in improving outcomes. Journal of Clinical Nursing,
20(19-20):2689.
Stone, G.W., Teirstein, P.S., Meredith, I.T., Farah, B., Dubois, C.L., Feldman, R.L., Dens, J., Hagiwara, N., Allocco, D.J.,
Dawkins, K.D. & PLATINUM Trial Investigators (Whitbourn, R.). (2011). A prospective, randomized evaluation of a
novel everolimus-eluting coronary stent: The PLATINUM (A prospective, randomized, multicenter trial to assess an
everolimus-eluting coronary stent system [PROMUS Element] for the treatment of up to two de novo coronary artery
lesions) trial. Journal of the American College of Cardiology, 57(16):1700-1708.
Sung, K.C., Rhee, E.J., Kim, H., Park, J.B., Kim, Y.K., Woo, S. & Wilson, A.M. (2011). An elevated apolipoprotein B/AI
ratio is independently associated with microalbuminuria in male subjects with impaired fasting glucose. Nutrition,
Metabolism & Cardiovascular Diseases, 20(10):615-621
Symplicity HTN-1 Investigators (Whitbourn, R.) (2011). Catheter-based renal sympathetic denervation for resistant
hypertension: Durability of blood pressure reduction out to 24 months. Hypertension, 57(5):911-917.
Thompson, D.R., Chair, S.Y., Chan, S.W., Astin, F., Davidson, P.M. & Ski, C.F. (2011). Motivational interviewing: A useful
approach to improving cardiovascular health? Journal of Clinical Nursing, 20(9-10):1236-1244.
Thompson, D.R. & Ski, C.F. (2011). International collaboration in cardiovascular nursing research. Heart & Lung: Journal
of Acute and Critical Care, 40(5):389-390.
Thompson, D.R. & Watson, R. (2011). Mokken scaling of the Myocardial Infarction Dimensional Assessment Scale
(MIDAS). Journal of Evaluation in Clinical Practice, 17(1):156-159.
Wang, W., Ski, C.F., Thompson, D.R. & Hare, D.L. (2011). A psychometric evaluation of the Chinese version of the short
form Cardiac Depression scale. Psychomatics, 52(5):450-4.
Waseda, K., Ako, J., Yamasaki, M., Koizumi, T., Sakurai, R., Hongo, Y., Koo, B.K., Ormiston, J., Worthley, S.G., Whitbourn, R.J.,
Walters, D.L., Meredith, I.T., Fitzgerald, P.J. & Honda, Y. (2011). Impact of Polymer Formulations on Neointimal Proliferation
After Zotarolimus-Eluting Stent With Different Polymers Insights From the RESOLUTE Trial. Circulation: Cardiovascular
Interventions, 4(3):248-55.
Whalley, B., Rees, K., Davies, P., Bennett, P., Ebrahim, S., Liu, Z., Rees, K., West, R., Moxhan, T., Thompson, D.R. & Taylor,
R.S. (2011). Psychosocial interventions for coronary heart disease. Cochrane Database Syst Rev 2011, 7:CD002902.
Wilson, A.M., Sadrzadeh-Rafie, A.H., Myers, J., Assimes, T., Nead, K.T., Higgins, M., Gabriel, A., Olin, J. & Cooke, J.P. (2011).
Low lifetime recreational activity is a risk factor for peripheral arterial disease. Journal of Vascular Surgery, 54(2):427-432.
Worrall-Carter, L., Ski, C., Scruth, E., Campbell, M. & Page, K. (2011). Systematic review of cardiovascular disease in
women: Assessing the risk. Nursing & Health Sciences, 13(4):529-535.
Yu, D.S.F., Lee, D.T.F., Thompson, D.R., Jaarsma, T., Woo, J. & Leung, E.M. (2011). Psychometric properties of the Chinese
version of the European heart railure self-care behavior scale. International Journal of Nursing Studies, 48(4):458-467.
2010
Abizaid, A.C., Botelho, R., Verheye, S., Meredith, I. T., Costa, J. R., Staico, R. & Whitbourn, R.J. (2010). CARE II 8
month follow-up results with the CardioMind® 0.014null Sparrow® sirolimus-eluting nitinol stent system. Journal of
the American College of Cardiology, 56(13):B53.
Askham, J., Kuhn, L., Frederiksen, K., Davidson, P., Edward, K. & Worrall-Carter, L. (2010). The information and support needs
of Faroese women hospitalised with an acute coronary syndrome. Journal of Clinical Nursing, 19(9-10):1352-1361.
Botelho, R., Verheye, S., Whitbourn, R.J., Staico, R., Costa, J. R. & Abizaid, A. C. (2010). Clinical experience with a
sirolimus-eluting nitinol stent in a biodegradable polymer matrix using the CardioMind® 0.014null Sparrow® stent
system. Journal of the American College of Cardiology, 55(10):A217.E2061.
Burns, A.T., Gutman, J. & Whitbourn, R. (2010). Side-branch wire entrapment during bifurcation PCI: Avoidance and
management. Catheterization and Cardiovascular Interventions, 75(3):351-353.
Cameron, J., Worrall- Carter, L., Page, K. & Stewart, S. (2010). Self-care behaviours and heart failure: Does experience
with symptoms really make a difference? European Journal of Cardiovascular Nursing, 9(2):92-100.
CvRC Annual Report 2010-2011
27
Publications 2010 (cont.)
Cameron, J., Worrall-Carter, L., Page, K., Riegel, B., Lo, S. & Stewart, S. (2010). Does cognitive impairment predict
poor self-care in patients with chronic heart failure? European Journal of Heart Failure, 12(5):508-515.
Chamie, D., Costa Jr, J.R., Abizaid, A., Feres, F., Staico, R., Devito, F., Costa, R. A., Tanajura, L. F., Sousa, A.G.M.R.,
Fitzgerald, P.J., Whitbourn, R.J. & Sousa, J.E. (2010). Serial angiography and intravascular ultrasound: Results of
the SISC Registry (Stents In Small Coronaries). JACC: Cardiovascular Interventions, 3(2):191-202.
Chau, J.P.C., Lam, L.W., Lui, M.H.L., Ip, W.Y., Chien, W.T., Lee, I.F.K. & Thompson, D.R. (2010). A survey of registered
nurses’ perceptions of the code of professional conduct in Hong Kong. Journal of Clinical Nursing, 19(22-23):3527-34.
Clark, A.M. & Thompson, D.R. (2010). What heart failure programme works best? Wrong question, wrong assumptions.
European Journal of Heart Failure, 12(12):1271-3.
Cooke, J.P. & Wilson, A.M. (2010). Biomarkers of peripheral arterial disease. Journal of the American College of
Cardiology, 55(19):2017-23.
Duffy, S.J., Ruygrok, P., Juergens, C. P., Sievert, H., Richards, M., Blake, J., Whitbourn, R., Omar Farouque, H., Pertile,
T. & Kaye, D. M. (2010). Removal of contrast media from the coronary sinus attenuates renal injury after coronary
angiography and intervention. Journal of the American College of Cardiology, 56(6):525-526.
Duffy, S., Ruygrok, P., Juergens, C., Sievert, H., Richards, M., Blake, J., Whitbourn, R., Farouque, O., Pertile, T. & Kaye,
D. (2010). Removal of contrast media from the coronary sinus attenuates renal injury after coronary angiography
and intervention. Heart Lung and Circulation, 19:S149.
Esler, M., Schlaich, M., Whitbourn, R., Walton, A. & Krum, H. (2010). Mechanism and durability of blood pressure
reduction with catheter-based denervation in essential hypertension. Clinical Autonomic Research, 20(5):301.
Gholizadeh, G., Davidson, P., Salamonson, Y. & Worrall-Carter, L. (2010). Theoretical considerations in reducing risk for
cardiovascular diseases: Implications for nursing practice. Journal of Clinical Nursing, 19:2137-2145.
Gomez-Lara, J., Garcia-Garcia, H. M., Onuma, Y., Garg, S., Regar, E., De Bruyne, B., Windecker, S., McClean, D., Thuesen,
L., Dudek, D., Koolen, J., Whitbourn, R., Smits, P. C., Chevalier, B., Dorange, C., Veldhof, S., Morel, M. A., De Vries,
T., Ormiston, J. A. & Serruys, P. W. (2010). A comparison of the conformability of everolimus-eluting bioresorbable
vascular scaffolds to metal platform coronary stents. JACC:Cardiovascular Interventions, 3(11):1190-1198.
Griffin, M.D., Wilson, L.M., Mok, Y.F., Januszewski, A.S., Wilson, A.M., Karschimkus, C.S., Romas, E., Lee, A.B.,
Godfrey, T., Wong, M., Clemens, L., Jenkins, A.J. & Howlett ,G.J. (2010) Thioflavin T fluorescence in human serum:
Correlations with vascular health and cardiovascular risk factors. Clinical Biochemistry, 43(3): 278-86.
Kereiakes, D. J., Cannon, L. A., Feldman, R. L., Popma, J. J., Magorien, R., Whitbourn, R., Dauber, I. M., Rabinowitz, A. C., Ball,
M. W., Bertolet, B., Kabour, A., Foster, M. C., Wang, J. C., Underwood, P. & Dawkins, K. D. (2010). Clinical and angiographic
outcomes after treatment of de novo coronary stenoses with a novel platinum chromium thin-strut stent: Primary results of
the PERSEUS (prospective evaluation in a randomized trial of the safety and efficacy of the use of the TAXUS element
paclitaxel-eluting coronary stent system) trial. Journal of the American College of Cardiology, 56(4):264-271.
Kume, T., Waseda, K., Koo, B. K., Botelho, R., Verheye, S., Whitbourn, R., Meredith, I., Worthley, S., Hai, K. T., Yock,
P. G., Honda, Y., Abizaid, A. & Fitzgerald, P. J. (2010). Intravascular ultrasound analysis of small coronary lesions
treated with the CardioMind Coronary Stent system: IVUS results of the CARE II trial. Journal of the American
College of Cardiology, 56(13):B51-B52.
McCann, A., MacIsaac, A. & Whitbourn, R.J. (2010). Late drug-eluting stent thrombosis: Importance of intravascular
ultrasound. Cardiovascular Revascularization Medicine, 11(1):52-56.
Meredith, I. T., Worthley, S. G., Walters, D. L. & Whitbourn, R. (2010). Four-year clinical outcomes from the RESOLUTE
first-in-man trial. Journal of the American College of Cardiology, 56(13):B55.
Meredith, I.T., Worthley, S.G., Whitbourn, R., Walters, D., McClean, D., Ormiston, J., Horrigan, M., Wilkins, G.T., Hendriks, R.,
Matsis, P., Muller, D. & Cutlip, D.E. (2010). Long-term clinical outcomes with the next-generation Resolute Stent System: A
report of the two-year follow-up from the RESOLUTE clinical trial. EuroIntervention, 5(6):692-697.
Okamura, T., Onuma, Y., Garcia-Garcia, H.M., Regar, E., Wykrzykowska, J.J., Koolen, J., Thuesen, L., Windecker, S.,
Whitbourn, R., McClean, D.R., Ormiston, J.A. & Serruys, P.W., for the Absorb Cohort B Investigators. (2010).
3-Dimensional optical coherence tomography assessment of jailed side branches by bioresorbable vascular
scaffolds a proposal for classification. JACC: Cardiovascular Interventions, 3(8):836-844.
Ormiston, J., Meredith, I., Walters, D., Walton, T., Pasupati, S., Muller, D., Worthley, S., Yong, G. & Whitbourn, R. (2010).
Early effectiveness and safety results from the CoreValve transcatheter aortic valve Australia-New Zealand study.
Heart, Lung and Circulation, 19:S241.
Ormiston, J., Meredith, I., Walters, D., Walton, T., Pasupati, S., Mutter, D., Worthley, S., Yong, G. & Whitbourn, R. (2010).
Early effectiveness and safety results from the CoreValve transcatheter aortic valve Australia-New Zealand study.
Journal of the American College of Cardiology, 56(13):B112-B113.
Page, K., Davidson, P., Edward, K., Allen, J., Cummins, R., Thompson, D. & Worrall-Carter, L. (2010). Recovering from
an acute cardiac event – The relationship between the depression and life satisfaction. Journal of Clinical Nursing,
19(5-6):736-743.
28
Riegel, B., Dickson, V., Cameron, J., Bunker, S., Johnson, J., Page, K. & Worrall-Carter, L. (2010). Symptom recognition
in elders with heart failure. Journal of Nursing Scholarship, 42(1):92-100.
Riegel, B., Dickson, V., Kuhn, L., Page, K. & Worrall-Carter, L. (2010). Gender-specific barriers and facilitators to heart
failure self-care: A mixed methods study. International Journal of Nursing Studies, 47(7):888-895.
Sakata, K., Koo, B.K., Nakatani, D., Waseda, K., Ako, J., Yock, P.G., Honda, Y., Whitbourn, R., Worthley, S., Meredith,
I. & Fitzgerald, P.J. (2010). First-in-man ivus findings using the medtronic bifurcation stent in patients with coronary
bifurcation lesions. Journal of the American College of Cardiology, 55(10):A199.E1873.
Sakata, K., Koo, B.K., Waseda, K., Nakatani, D., Yoek, P.G., Honda, Y., Whitbourn, R., Worthiey, S.G., Ormiston, J.,
Wilkins, G.T., Meredith, I.T. & Fitzgerald, P.J. (2010). Impact of bifurcation angioplasty on side branch ostium:
Insights from BRANCH trial. Journal of the American College of Cardiology, 56(13):B2-B3.
Schlaich, M. P., Krum, H., Sobotka, P. A., Walton, A., Whitbourn, R., Thambar, S., Chopra, R. & Esler, M. D. (2010). Is
catheter-based renal denervation associated with a sustained blood pressure reduction in patients with resistant
hypertension? Complete 12 months safety and efficacy results. Hypertension, 55(6):1508.
Schlaich, M., Krum, H., Walton, T., Whitbourn, R., Sobotka, P. & Esler, M. (2010). Two-year durability of blood pressure
reduction with catheter-based renal sympathetic denervation. Journal of Hypertension, 28:e446.
Shields, L., Watson, R. & Thompson, D.R. (2010). A new government in the UK: Possible ramifications for children’s
nursing. Neonatal Paediatric& Child Health Nursing, 13(2):1-2.
Ski, C.F. & Thompson, D.R. (2010). Commentary on Tolmie, E.P., Lindsay, G.M., Kelly, T., Tolson, D., Baxter, S. & Belcher,
P.R. (2009). Are older patients’ cardiac rehabilitation needs being met? Journal of Clinical Nursing, 19:2948–2949.
Ski, C.F. & Thompson, D.R. (2010). Quality of life in cardiovascular disease: What is it and why and how should we
measure it? European Journal of Cardiovascular Nursing, 9(4):201-2.
Waseda, K., Ako, J., Yamasaki, M., Koizumi, T., Ormiston, J., Worthley, S.G., Whitbourn, R.J., Walters, D.L., Honda, Y.,
Meredith, I.T. & Fitzgerald, P.J. (2010). Short-and mid-term intravascular ultrasound analysis of the new zotarolimuseluting stent with durable polymer: Results from the RESOLUTE trial. Circulation Journal, 74(10):2097-2102.
Waseda, K., Hasegawa, T., Ako, J., Honda, Y., Grube, E., Whitbourn, R., Ormiston, J., O’Shaughnessy, C.D., Henry, T.D.,
Overlie, P., Schwartz, L.B., Sudhir, K., Chevalier, B., Gray, W.A., Yeung, A.C. & Fitzgerald, P.J. (2010). Comparison
of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation-pooled IVUS results from
the zomaxx i and ii trials. Circulation Journal, 74(11):2334-2339.
Wilson, A.M., Shin, D. S., Weatherby, C., Harada, R.K., Ng, M.K., Nair, N., Kielstein, J. & Cooke, J.P. (2010). Asymmetric
dimethylarginine correlates with measures of disease severity, major adverse cardiovascular events and all-cause
mortality in patients with peripheral arterial disease. Vascular Medicine, 15(4):267-274.
Presentations
2011
Cameron, J. (2011). Using the Montreal Cognitive Assessment to screen for mild cognitive impairment in patients with
heart failure. Cardiac Society of Australia and New Zealand 58th ASM, Adelaide, Australia. 9 August.
Cameron, J., Ski, C.F. & Thompson, D.R. (2011). Chronic heart failure patient re-admissions and premature deaths:
Identifying key variables. Heart Foundation National Conference, Melbourne, Australia. 19 March.
Ski, C.F., Page, K., Cameron, J., Thompson, D.R., Gilbert, M., Salzberg, M., MacIsaac, A. & Worrall-Carter, L. (2011).
Clinical outcomes: Screening of depression in cardiac patients. Heart Foundation National Conference, Melbourne,
Australia. 19 March.
Thompson, D.R. (2011). Nursing in a time of change. 20th Anniversary Nethersole School of Nursing Keynote Seminar,
Sha Tin, Hong Kong. 13 June.
Thompson, D.R. (2011). Psychosocial aspects of coronary heart disease. 5th Australasian Cardiovascular Nursing
College Annual Conference, Melbourne, Australia. 18 March.
Whitbourn, R. (2011). Ardian Renal Sympathetic denervation. Invited panel member, Opening session, Euro PCR
meeting, Paris, France. 17-20 May.
2010
Cameron, J., Worrall-Carter, L., Page, K., Riegel, B. & Stewart, S. (2010). Using the Montreal Cognitive Assessment
to Screen for Mild Cognitive Impairment in Patients with Heart Failure. (Accepted for presentation in the Junior
Investigator Oral Catagory). Paper presented at the St Vincent’s Research Week. St Vincent’s Hospital, Melbourne,
Australia. 23-25 August.
CvRC Annual Report 2010-2011
29
Presentations 2010 (cont.)
Cameron, J., Worrall-Carter, L., Page, K., Riegel, B. & Stewart, S. (2010). Identifying mild cognitive impairment – what
is the relationship with self-care in heart failure patients? (Winner Affiliates Prize session). Paper presented at the
Cardiac Society of Australia and New Zealand 58th Annual Scientific Meeting, Adelaide, Australia. 5-8 August.
Cameron, J., Worrall-Carter, L., Page, K. & Stewart, S. (2010). Does experience necessarily equal better self-care in
patients with chronic heart failure? Poster presented at the St Vincent’s Research Week, St Vincent’s Hospital,
Melbourne, Australia. 23-25 August.
Cameron, J., Worrall-Carter, L., Page, K. & Stewart, S. (2010). Self-care skills can remain poor despite more than two
months experience with CHF symptoms. Poster presented at the Australasian Cardiovascular Nursing College
(ACNC) Annual Conference, Brisbane, Australia. 12-13 March.
Kuhn, L., Page, K. & Worrall-Carter, L. (2010). The impact of patient gender on triage of acute coronary syndrome in
Victorian emergency departments. Moderated poster presented at the St Vincent’s Research Week, St Vincent’s
Hospital, Melbourne, Australia. 23-25 August.
Kuhn, L., Page, K., Davidson, P. & Worrall-Carter, L. (2010). A comparison of triage allocation for women and men for acute
coronary syndrome across Victorian emergency departments. Paper presented at the 8th International Conference for
Emergency Nursing of the College of Emergency Nursing Australasia, Canberra, Australia. 14-16 October.
Kuhn, L., Page, K., Davidson, P. & Worrall-Carter, L. (2010). A comparison of triage allocation for women and men
for acute coronary syndrome across Victorian emergency departments. Poster presented at the Australasian
Cardiovascular Nursing College (ACNC) Annual Conference, Brisbane, Australia. 12-13 March.
Page, K. & Wilson, A. (2010). Cardiovascular Disease Prevention Group. Presented at the St Vincent’s Research Week,
St Vincent’s Hospital Melbourne, Australia. 23-25 August.
Page, K., Ski, C., Cameron, J., Thompson, D., Gilbert, M., Salzberg, M., MacIssac, A. & Worrall-Carter, L. (2010).
Improving screening and referral practices for depression in CHD patients. (Winner Senior Investigator Prize). Paper
presented at the St Vincent’s Research Week, St Vincent’s Hospital Melbourne, Australia. 23-25 August.
Ski, C., Page, K., Cameron, J., Thompson, D., Gilbert, M., Salzberg, M., MacIssac, A. & Worrall-Carter, L. (2010).
Clinical outcomes: Screening of depression in cardiac patients. Paper presented at the Heart Foundation National
Conference, Melbourne, Australia. 17-19 March.
Thompson, D.R. (2010). Cardiac rehabilitation in multi-cultural populations. Australian Cardiovascular Health and
Rehabilitation Association Annual Conference, Canberra, Australia. 14 August.
Thompson, D.R. (2010). Meeting the Challenges in cardiovascular nursing research. Cardiac Society of Australia and New
Zealand 58th Annual Scientific Meeting, Adelaide, Australia. 5 August.
Thompson, D.R. (2010). The challenges for cardiovascular nursing research. Cardiac Society of Australia and New Zealand
58th Annual Scientific Meeting, Adelaide, Australia. 8 August.
Thompson, D.R. (2010). The psychosocial component of cardiac rehabilitation: Time to practice what we preach.
Victorian State conference, Back to Basics: A team approach to Risk Factor Management, incorporating the Alan
Goble Lecture, Melbourne, Australia. 7 October.
Whitbourn, R. (2010). Case presentation. Presented at the EuroPCR meeting, Paris, France. 25-28 May.
Whitbourn, R. (2010). DES failures & complications. Presented at the TCT meeting, Washington DC, USA. 21-25 September.
Whitbourn, R. (2010). How to treat Theatre: Coronary Artery Disease 1: Management of Mulitvessel Disease. Presented at
the TCT meeting, Washington DC, USA. 21-25 September.
Whitbourn, R. (2010). Oral Abstracts: Bifurcation Lesions. Presented at the TCT meeting. Washington DC, USA. 2010
Whitbourn, R. (2010). The Drug-Eluting Stent Summit (Part 1): Appropriate Utilization of Current Generation Devices.
Presented at the TCT meeting, Washington DC, USA. 21-25 September.
Whitbourn, R. (2010).Live Cases: Multivessel Disease. Unprotected left Main Disease II, Patient Selection and Technique.
Presented at the TCT meeting, Washington DC, USA. 21-25 September.
Whitbourn, R. & Wilson, A. (2010). Overview of the major randomised trials of second generation Drug-Eluting Stents
(DES). Presented at the Cardiac Society of Australia and New Zealand 58th Annual Scientific Meeting, Adelaide,
Australia. 5-8 August.
Worrall-Carter, L. (2010). Building capacity in cardiovascular nursing through health service research. Presented at
The Bio21 Cluster conference. Clinical research matters: Establishing the Victorian Clinical Researcher Network,
Melbourne, Australia. 29 March.
Worrall-Carter, L. (2010). Building capacity in cardiovascular nursing. Paper presented at the Australasian Cardiovascular
Nursing College (ACNC) Annual Conference, Brisbane, Australia. 12-13 March.
Worrall-Carter, L. (2010). Developing a research career in cardiovascular nursing. Workshop facilitator and invited
presenter at the Australasian Cardiovascular Nursing College Annual Conference, Brisbane, Australia, 12-13 March.
Worrall-Carter, L., Page, K., Gilbert, M., Salzberg, M., Edward, K. L. & Ski, C. (2010). Screening of depression and
anxiety in cardiac patients: Working toward a clinical pathway. Poster presented at the Australasian Cardiovascular
Nursing College Annual Conference, Brisbane, Australia. 12-13 March.
30
Affiliated outcomes
Affiliated Books
2011
Morgan, V.A., Waterreus, A., Jablensky, A., Mackinnon, A., McGrath, J., Carr, V., Bush, R., Castle, D., Cohen, M., Harvey,
C., Galletly, C., Stain, H.J., Neil, A., McGorry, P., Hocking, B., Shah, S. & Saw, S. (2011). People Living with Psychotic
Illness 2010: Report on the Second Australian National Survey. Commonwealth Department of Health and Aged
Care, Canberra.
2010
Castle, D.J. (2010). A Primer in Clinical Psychiatry. Sydney: Elsevier, ISBN 978-0-7295-3903-6.
Castle, D.J. & Buckley, P.F. (2010). Schizophrenia. Oxford: Oxford University Press, ISBN 978-0-19-954961-0.
Salzberg, M. & Castle, D. (2010). Physical and Mental Health: The Interface. Australian Postgraduate Medicine,
Melbourne, ISBN 978-0-646-52112-1.
Affiliated Book Chapters
2011
Nicholson, E. & Castle, D.J. (2011). Medical morbidity in people with schizophrenia. In: Schizophrenia: The Final Frontier.
(Eds: David, A.S., Kapur, S. & McGuffin, P.), East Sussex: Psychology Press, 343-356.
2010
Jones, S. & Castle, D. (2010). Obesity in schizophrenia. In: Physical and Mental Illness. (Eds: Salzberg, M. & Castle,
D.J.) Melbourne: The Interface, Australian Postgraduate Medicine, 153-166.
Schultz, H. & Castle, D. (2010). Depression and HIV. In: Physical and Mental Illness. (Eds: Salzberg, M. & Castle, D.J.)
Melbourne: The Interface, Australian Postgraduate Medicine, 153-166.
Trauer, T. & Castle, D.J. (2010). Symptom severity outcome measures for depression. In: Outcome Measurement in
Psychiatry 3rd Edition. (Eds: Thornicroft, G. & Tansella, M.), London: Royal College of Psychiatrists, 237-250.
Affiliated Publications
2011
Advani, A., Huang, Q., Thai, K., Advani, S.L., White, K.E., Kelly, D.J., Yuen, D.A., Connelly, K.A., Marsden, P.A. &
Gilbert, R.E. (2011) Long-term administration of the histone deacetylase inhibitor, vorinostat, attenuates renal injury
in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. American Journal of
Pathology, 178(5):2205-2214.
Advani, A., Wiggins, K.J., Cox, A.J., ZhangR, Y., Gilbert, R.E. & Kelly, D.J. (2011) Inhibition of the epidermal growth
factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy. Nephrology,
16(8):573-81
Baker, A.L., Kay-Lambkin, F.J., Richmond, R., Filia, S., Castle, D.J., Williams, J. & Lewin,T.J. (2011). Study protocol: a
randomised controlled trial investigating the effect of a healthy lifestyle intervention for people with severe mental
disorders. BMC Public Health, 11:10.
Better, N., Webb, M.B., Prior, D.L., Unger, S.A. & Larcos, G. (2011). A new algorithm for the management of stable
coronary artery disease incorporating CT coronary angiography and fractional flow reserve: How we can improve
outcomes and reduce costs. The Medical Journal of Australia, 194(12):668-669.
Bruaene, A.V., La Gerche A., Prior D.L., Voigt, J., Delcroix, M. & Budts, W. (2011). Pulmonary vascular resistance as
assessed by bicycle stress echocardiography in patients with ASD type secundum. Circulation – Cardiovascular
Imaging, 4(3):237-45.
CvRC Annual Report 2010-2011
31
Affiliated Publications 2011 (cont.)
Buchanan, B.G., Rossell, S.L. & Castle, D.J. (2011). Body dysmorphic disorder: A review of nosology, cognition and
neurobiology, Neuropsychiatry, 1:71-80.
Burns, A., Murch, S., Layland, J., La Gerche, A., MacIsaac, A. & Prior, D. (2011). Effect of adenosine on pulmonary
vascular resistance in patients with pulmonary hypertension due to left heart disease and scleroderma. Heart Lung
& Circulation, 14S:S14.
Campbell, D.J., Somaratne, J.B., Jenkins, A.J., Prior, D.L., Yii, M., Kenny, J.F., Newcomb, A.E., Schalkwijk, C.J., Black,
M.J. & Kelly, D.J. (2011). Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and
microvasculature of men with coronary artery, Cardiovascular Diabetology, 10:80.
Campbell, D.J., Somaratne, J.B., Jenkins, A.J., Prior, D.L., Yii, M., Kenny, J.F., Newcomb, A.E., Kelly, D.J. & Black, M.J.
(2011). Differences in myocardial structure and coronary microvasculature between men and women with coronary
artery disease. Hypertension, 57(2):186-92.
Campbell, D.J., Zhang, Y., Kelly, D.J., Gilbert, R.E., McCarthy, D.J., Shi, W. & Smyth, G.K (2011) Aliskiren increases bradykinin
and tissue kallikrein mRNA levels in the heart. Clinical and Experimental Pharmacology and Physiology, 38(9):623-31.
Castle, D. (2011). Early intervention in psychosis: Should it be the focus for mental health services? Advances in
Psychiatric Treatment, 17:398-400.
Castle, D., Berk, M. & Hocking, B. (2011). Bipolar disorder needs a broader perspective. The Medical Journal of Australia,
194:326.
Castle, D.J. (2011). Letter from Australia: Mental healthcare in Victoria. Advances in Psychiatric Treatment, 17:2-4.
Chan, E., Taylor, D., Phillips, G., Castle, D.J., D, Knott, J. & Kong, D. (2011). May I have your consent? Informed consent
in clinical trials – Feasibility in emergency situations. Journal of Psychiatric Intensive Care, 7(2):109-113.
Coller, J., McGrady, M., Shiel, L., Reid, C., Boffa, B., Liew, D., Stewart, S., Wolfe, R., Krum, H., Campbell, D. & Prior,
D. (2011). Relationship between amino-terminal Pro-B-Type natriuretic peptide (NT-proBNP) and left atrial volume
index in older subjects at risk of heart failure. Heart Lung & Circulation, 14S:S76.
Connelly, K.A., Advani, A., Kim, S., Advani, S.L., Zhang, M., White, K.E., Kim, Y.M., Parker, C., Thai, K., Krum, H., Kelly,
D.J. & Gilbert, R.E. (2011) The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and
is increased in experimental diabetic cardiomyopathy. Journal of Hypertension. 29(6):1175-1184.
Dixon, B., Nixon, I., Kenny, J., Newcomb, A.E., Rosalion, A., Opeskin, K., Stamaratis, G., Silbert, B.S., Said, S.,
Santamaria, J.D. & Campbell, D.J. (2011). Aprotinin, but not tranexamic acid, is associated with increased pulmonary
microvascular fibrin deposition after cardiac surgery. Thrombosis Research, 127(3):272-4.
Dixon, B., Opeskin, K., Stamaratis, G., Nixon, I., Yii, M., Newcomb, A.E., Rosalion, A., Zhang, Y., Santamaria, J.D. &
Campbell, D.J. (2011). Pre-operative heparin reduces pulmonary microvascular fibrin deposition following cardiac
surgery. Thrombosis Research, 127(1):e27-30.
Gnaneswaran, N., Pang, B., La Gerche, A., MacIsaac, A., Prior, D. & Burns, A. (2011). Comparison of Doppler-derived
methods to predict invasive mean pulmonary artery pressure at rest and after exercise in patients with scleroderma.
Heart Lung & Circulation, 14S:S164.
Inder, W. & Castle, D. (2011). Antipsychotic-induced hyperprolactinaemia. Australian and New Zealand Journal of
Psychiatry, 45:830-837.
Khong, F.L., Zhang, Y., Edgley. A.J., Qi, W., Connelly, K.A., Woodman, O.L., Krum, H. & Kelly, D.J. (2011).
3’,4’-Dihydroxyflavonol antioxidant attenuates diastolic dysfunction and cardiac remodeling in streptozotocininduced diabetic m(Ren2)27 rats. PLoS One, 6(7):e22777.
La Gerche, A., MacIsaac, A.I. & Prior, D.L. (2011). Should pre-participation cardiovascular screening for competitive athletes
be introduced in Australia? A timely debate in a sport-loving nation. Heart Lung and Circulation, 20(10):629-633.
La Gerche A., Prior D.L. & Heidbuchel, H. (2011). Strenuous endurance exercise: Is more better for everyone? Our
genes won’t tell us. British Journal of Sports Medicine, 45(3):162-164.
Labuschange, I., Castle, D.J. & Rossell, S.L. (2011).What the cognitive deficits in body dysmorphic disorder tell us about
the underlying neurobiology: A review of three cases. International Journal of Cognitive Therapy, 4:21-33.
Lau, D.H., Psaltis, P.J., Carbone, A., Kelly, D.J., Mackenzie, L., Worthington, M., Metcalf,R.G., Kuklik, P., Nelson, A.J.,
Zhang, Y., Wong, C.X., Brooks, A.G., Saint, D.A., James, M.J.,Edwards, J., Young, G.D., Worthley, S.G. & Sanders,
P. (2011) Atrial protective effects of n-3 polyunsaturated fatty acids: A long term study in ovine chronic heart failure.
Heart Rhythm, 8(4):575-582.
Lau, D.H., Psaltis, P.J., MacKenzie, L., Kelly, D.J., Carbone, A., Worthington, M., Nelson, A.J., Zhang, Y., Kuklik, P.,
Wong, C.X., Edwards, J., Saint, D.A., Worthley, S.G. & Sanders, P. (2011). Atrial remodeling in an ovine model
of anthracycline-induced nonischemic cardiomyopathy: Remodeling of the same sort. Journal of Cardiovascular
Electrophysiology, 22(2):175-82.
32
Lewis, S., Thomas, S.L., Blood, R.W., Castle, D., Hyde, J. & Komesaroff, P.A. (2011). ‘I’m searching for solutions’: Why
are obese individuals turning to the internet for help and support with ‘being fat’? Health Expectations, 14(4):339-350.
Lewis, S., Thomas, S.L., Hyde, J., Castle, D. & Komesaroff, P.A. (2011). A qualitative investigation of obese men’s
experiences with their weight. American Journal of Health Behaviour, 35:458-469.
Paulsen, M.G., Dowsey, M.M., Castle, D.J. & Choong, P. (2011). Pre-operative psychological distress and functional
outcome after knee replacement. Australian and New Zealand Journal of Surgery, 81:681–687.
Pawsey, B., Logan, G., Castle, D.J. (2011). Psychological treatments for comorbidity across the lifecourse. Mental Health
and Substance Use: Dual Diagnosis, 4(1):72-82.
Qi, W., Holian, J., Tan, C.Y., Kelly, D.J., Chen, X.M. & Pollock, C.A. (2011) The roles of Kruppel-like factor 6 and
peroxisome proliferator-activated receptor-gamma in the regulation of macrophage inflammatory protein-3alpha at
early onset of diabetes. International Journal of Biochemistry & Cell Biology, 43(3):383-92.
Saxena, A., Dinh, D., Poh, C.L., Smith, J.A., Shardey, G. & Newcomb, A.E. (2011). Early and late outcomes after
concomitant aortic valve replacement and coronary artery bypass graft surgery in octogenarians: A multi-institutional
Australian study. Journal of the American Geriatrics Society, 59(9):1759-61.
Saxena, A., Dinh, D.T., Yap, C.H., Reid, C.M., Billah, B., Smith, J.A., Shardey, G.C. & Newcomb, A.E. (2011). Critical
analysis of early and late outcomes after isolated coronary artery bypass surgery in elderly patients. The Annals of
Thoracic Surgery, 92(5):1703-11.
Saxena, A., Poh, C.L., Dinh, D.T., Reid, C.M., Smith, J.A., Shardey, G.C. & Newcomb, A.E. (2011). Does patient gender
affect outcomes after concomitant coronary artery bypass graft and aortic valve replacement: An Australian society
of cardiac and thoracic surgeons database study. Cardiology, 119(2):116-123.
Sevar, K. & Castle, D. (2011). The physical health of the mentally ill: How can we help? The Australian Journal of
Psychosocial Rehabilitation, Winter:12-14.
Stubbs, S.L., Crook, J.M., Morrison, W.A. & Newcomb, A.E. (2011). Toward clinical application of stem cells for cardiac
regeneration. Heart Lung and Circulation, 20(3):173-179.
Tan, S.M., Zhang, Y., Cox, A., Qi, W. & Kelly, D.J. (2011). Tranilast attenuates the up-regulation of thioredoxin-interacting
protein and oxidative stress in an experimental model of diabetic nephropathy. Nephrology Dialysis Transplantation,
26(1):100-110.
Thomas, N., Rossell, S., Farhall, J., Shawyer, F. & Castle, D. (2011). Cognitive behavioural therapy for auditory hallucinations:
effectiveness and predictors of outcome in an outpatient setting. Behavioural and Cognitive Psychotherapy, 39:129-138.
Toh, W-L., Rossell, S.L. & Castle, D.J. (2011). Current visual scanpath research: A review of investigations into the
psychotic, anxiety and mood disorders. Comprehensive Psychiatry, 52:567-579.
Tokuyama, H., Kim, S., Zhang, Y., Langham, R.G., Cox, A.J., Gow, R.M., Kelly, D.J. & Gilbert, R.E. (2011). Protein kinase
C β inhibition ameliorates experimental mesangial proliferative glomerulonephritis. Nephrology, 16(7):649-55.
Wyman, K.M., Chamberlain, J.A. & Castle, D.J. (2011). Anxiety, psychosis and substance use: prevalence, correlates
and recognition in an outpatient mental health setting. African Journal of Psychiatry, 14:218-224.
2010
Bosanac, P., Patton, G. & Castle, D.J. (2010). Early intervention in psychotic disorders: Faith before facts? Psychological
Medicine, 40(3):353-358.
Burns A.T., La Gerche, A., D’Hooge, J., MacIsaac, A.I. & Prior, D.L. (2010). Left ventricular strain and strain rate:
Characterisation of the effect of load in human subjects. European Journal of Echocardiography, 11(3):283-9.
Burns, A.T., La Gerche, A., MacIsaac A.I. & Prior D.L. (2010). Left ventricular torsion parameters are affected by acute
changes in load. Echocardiography, 27(4):407-14.
Campbell, D. J., Kladis, A., Zhang, Y., Jenkins, A. J., Prior, D.L., Yii, M., Kenny, J.F., Black, M.J. & Kelly, D.J. (2010).
Increased tissue kallikrein levels in type 2 diabetes. Diabetologia, 53(4):779-785.
Campbell, D., Prior, D., Jenkins, A., Yii, M., Kenny, J., Newcomb, A., Kelly, D. & Black, M. (2010). Does reduced
myocardial capillary length density predispose to Non-ST-Segment-Elevation myocardial infarction in patients with
coronary artery disease? Heart and Lung Circulation, 19:S25.
Castle, D. (2010). Depersonalisation (by M Sierra). Acta Neuropsychiatrica, 22:98-99.
Castle, D., Berk, M. & Hocking, B. (2010). Bipolar disorder: New understandings, emerging treatments. The Medical
Journal of Australia, 193(4):S3-S4.
Castle, D., Gilbert, M., Lauder, S., Murray, G., Chamberlain, J., White, C., Berk, M. & Berk, L. (2010). Group-based
psychosocial intervention in bipolar disorder. British Journal of Psychiatry, 197:246.
CvRC Annual Report 2010-2011
33
Affiliated Publications 2010 (cont.)
Castle, D., Patton, G. & Bosanac, P. (2010). Early intervention in psychosis. Psychological Medicine, 40:2108-2109.
Castle, D.J. & Bassett, D. (2010). Highs and lows of bipolar disorder: Modern treatments. Psychiatric Medicine in General
Practice, 1:4-7.
Castle. D.J., Holdsworth, C., Chamberlain, J., Berk, M., Berk, L., Lauder, S., Murray, G., Schweitzer, I., Piterman, L. &
Gilbert, M. (2010). Group-based psychosocial intervention for bipolar disorder: Randomised controlled trial. British
Journal of Psychiatry, 196(5):383-388.
Dahiya, A., Vollbon, W., Jellis, C., Prior, D., Wahi, S., & Marwick, T. (2010). Echocardiographic assessment of raised pulmonary
vascular resistance: Application to diagnosis and follow-up of pulmonary hypertension. Heart, 96(24):2005-2009.
Dunai, J., Labauschagne, I., Castle, D.J., Kyrios, M. & Rossell, S.L. (2010). Executive function in body dysmorphic
disorder. Psychological Medicine, 40(9):1541-1548.
Kompa, A., Wang B.H., Phrommintikul, A., Ho, P., Kelly, D.J., Behm, D.J., Douglas, S.A & Krum, H (2010). Chronic
urotensin II receptor sntagonist treatment does not alter hypertrophy or fibrosis in a rat model of pressure-overload
hypertrophy. Peptides, 31(8):1523-1530.
La Gerche, A., Burns, A., Mooney, D. , Heidbuchel, H., MacIsaac, A. & Prior, D. (2010). Cardiac injury following intense
endurance exercise predominantly affects the right ventricle and increases with exercise duration and pre-race
conditioning. European Heart Journal, 31(S1):303.
La Gerche, A., Burns, A., Mooney, D., Inder, W., Heidbüchel, H., MacIsaac, A. & Prior, D. (2010). Exercise-Induced
dilation of the pulmonary microvasculature, demonstrated by agitated contrast transit, predicts right ventricular
afterload and function. Heart and Lung Circulation, 19:S179.
La Gerche, A., Burns, A., Mooney, D., Inder, W., Taylor, A., Heidbüchel, H., MacIsaac, A. & Prior, D. (2010).
Disproportionate right ventricular load and remodelling in endurance athletes: A comparison with the left ventricle
using a novel minimally invasive method of calculating end-systolic wall stress. Heart and Lung Circulation, 19:S262.
La Gerche, A., Burns, A., Mooney, D., Taylor, A., Heidbüchel, H., MacIsaac, A. & Prior, D. (2010). Intense Prolonged
Exercise (IPE) causes acute Right Ventricular (RV) injury which may not always be completely reversible. Heart and
Lung Circulation, 19:S3.
La Gerche, A. & Gewillig, M. (2010). What limits cardiac performance during exercise in normal subjects and in healthy
Fontan patients? International Journal of Pediatrics, 2010: Article ID 791291.
La Gerche, A., Jurcut ,R. & Voigt, J.U. (2010). Right ventricular function by strain echocardiography. Current Opinion in
Cardiology, 22(5):430-436.
La Gerche, A., MacIsaac, A.I., Burns, A.T., Mooney, D.J., Inder, W.J., Voigt, J.U., Heidbüchel, H. & Prior, D.L. (2010).
Pulmonary transit of agitated contrast is associated with enhanced pulmonary vascular reserve and right ventricular
function during exercise. Journal of Applied Physiology, 109(5):1307-1317.
La Gerche, A., Prior, D.L. & Heidbüchel, H. (2010). Clinical consequences of intense endurance exercise must include
assessment of the right ventricle. Journal of American College of Cardiology, 56(15):1263.
La Gerche, A., Prior, D.L. & Heidbüchel, H. (2010). Strenuous endurance exercise: Is more better for everyone? Our
genes won’t tell us. British Journal of Sports Medicine, 45(3):162-164.
La Gerche, A., Robberecht. C., Kuiperi. C., et al. (2010). Lower than expected desmosomal gene mutation prevalence in
endurance athletes with complex ventricular arrhythmias of right ventricular origin. Heart, 96(16):1268-74.
Labuschagne, I., Castle, D.J., Dunai, J., Kyrios, M. & Rossell, S.L. (2010). An examination of delusional thinking and
cognitive styles in body dysmorphic disorder. Australian and New Zealand Journal of Psychiatry, 44(8):706-712.
Lau D.H., Mackenzie L, Kelly D.J., Psaltis P.J., Brooks, A.G., Worthington, M., Rajendram, A., Kelly, D.R., Zhang, Y.,
Kuklik, P., Nelson, A.J., Wong, C.X., Worthley, S.G., Rao, M., Faull, R.J., Edwards, J., Saint, D.A. & Sanders, P.
(2010). Hypertension and atrial fibrillation: Evidence of progressive atrial remodelling with electro-structural correlate
in a conscious chronically instrumented ovine model. Heart Rhythm, 7(9):1282-1290.
Lau, D.H, MacKenzie, L., Rajendram, A., Psaltis, P.J., Kelly, D.R., Spyropoulos, P., Zhang, Y., Olakkengil, S., Russell, C.H.,
Brooks, A.G., Faull, R.J., Saint, D.A., Kelly, D.J., Rao, M.M., Worthley, S.G. & Sanders, P. (2010). Characterization
of cardiac remodeling in a large animal ‘One-Kidney, One-Clip’ hypertensive model. Blood Pressure, 19(2):119-125.
Lau, D.H., MacKenzie, L., Kelly, D.J., Psaltis, P.J., Worthington, M., Rajendram, A., Kelly, D.R., Nelson, A.J., Zhang, Y.,
Kuklik, P., Brooks, A.G., Worthley, S.G., Faull, R.J., Rao, M., Edwards, J., Saint, D.A. & Sanders, P. (2010). Short
term hypertension is associated with the development of atrial fibrillation substrate: A study in an ovine hypertensive
model. Heart Rhythm, 7(3):396-404.
Lauder, S., Berk, M., Castle, D., Dodd, S. & Berk, L. (2010). The role of psychotherapy in bipolar disorder. The Medical
Journal of Australia, 193(4):S31-S35.
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Lekawanvijit, S., Adrahtas, A., Kelly, D.J., Kompa, A., Wang, B.H. & Krum, H. (2010). Does Indoxyl sulfate, a uraemic
toxin, have direct effects on cardiac fibroblasts and myocytes? European Heart Journal, 31(14):1771-1779.
Lewis, S., Thomas, S., Blood, W., Hyde, J., Castle, D. & Komesaroff, P. (2010). Do health beliefs and behaviours differ
according to severity of obesity? A qualitative study of Australian adults. International Journal of Environmental
Public Health, 7(2):443-459.
Lewis, S., Thomas, S., Hyde, J., Castle, D., Blood, W.R. & Komesaroff, P. (2010). ‘I don’t eat a hamburger and large chips every
day!’ A qualitative study of the impact of public health messages about obesity on obese adults. BMC Public Health, 10:309.
Liao, Y., Knoesen, N.P., Castle, D.J., Tang, J., Deng, Y., Bookun, R., Chen, X., Hao, W., Meng, G. & Liu,T. (2010).
Symptoms of disordered eating, body shape and mood concerns in male and female Chinese medical students.
Comprehensive Psychiatry, 51:516-523.
Liao, Y., Knoesen, N.P., Deng, Y., Tang, J., Castle, D.J., Bookun, R., Hao, W., Chen ,X. & Liu ,T. (2010). Body dysmorphic
disorder, social anxiety and depression in Chinese medical students. Social Psychiatry and Psychiatric Epidemiology,
45(10):963-971.
Lubman, D., King, J. & Castle, D.J. (2010). Treating comorbid substance use disorders in schizophrenia. International
Review of Psychiatry, 22(2):191-201.
Mancuso, S., Knoesen, N. & Castle, D.J. (2010). The Dysmorphic Concern Questionnaire: A screening measure for body
dysmorphic disorder. Australian and New Zealand Journal of Psychiatry, 44(6):535-542.
Mancuso, S.G., Knoesen, N.P. & Castle, D.J. (2010). Delusional versus nondelusional body dysmorphic disorder.
Comprehensive Psychiatry, 51(2):177-182.
Monshat, K., Carty, B., Olver, J., Castle, D.J. & Bosanac, P. (2010). Trends in antipsychotic prescribing practices in an
urban community mental health clinic. Australasian Psychiatry, 18(3):238-241.
Murch, S., Prior, D. & MacIsaac, A. (2010). A comparison of Local Referral Patterns for transthoracic echocardiography
versus ACC appropriateness criteria. Heart and Lung Circulation, 19:S160.
Neilson, K., Pollard, A., Boonzaier, A., Corry, J., Castle, D., Mead, K., Grey, M., Smith, D., Trauer, T. & Couper. J. (2010).
An investigation of psychological distress (depression and anxiety) in people with head and neck cancer. The
Medical Journal of Australia, 193:S48-S51.
Ng, C. & Castle, D. (2010). Pharmacogenetics from ethno-cultural perspectives. Sri Lanka Journal of Psychiatry, 1:29-31.
Organ, B., Nicholson, E. & Castle, D.J. (2010). Implementing a physical health strategy in a mental health service.
Australasian Psychiatry, 18(5):456-459.
Paddle, A., Elahi, M. & Newcomb, A. (2010). Retained foreign body following pleural drainage with a small-bore catheter.
General Thoracic and Cardiovascular Surgery, 58:42-44.
Petrakis, M., Hamilton, B., Penno, S., Selvendra, A., Baetens, D., Laxton, S., Doidge, G. & Castle, D.J. (2010). Fidelity to guidelines
using a care pathway in the treatment of first episode psychosis. Journal of Evaluation in Clinical Practice, 17:722-728.
Pfluger, H.B., Maeder, M.T., La Gerche, A. & Taylor, A.J. (2010). One- and two-dimensional estimation of right and left
ventricular size and function-comparison with cardiac magnetic resonance imaging volumetric analysis. Heart Lung
Circulation, 19(9):541-548.
Piterman, L., Jones, K. & Castle, D. (2010). Bipolar disorder in general practice: challenges and opportunities. The
Medical Journal of Australia, 193(4):S14-S17.
Prior, D. & Coller, J. (2010). Echocardiography in heart failure – A guide for general practice. Australian Family Physician,
39(12):904-9.
Rana, I., Stebbing, M., Kompa, A., Kelly, D.J., Krum, H. & Badoer, E. (2010). Microglia activation in the hypothalamic
PVN following myocardial infarction. Brain Research, 1326:96-104.
Tan, S.M., Zhang, Y., Connelly, K.A., Gilbert, R.E. & Kelly, D.J. (2010). Targeted inhibition of activin receptor-like kinase
5 signaling attenuates cardiac dysfunction following myocardial infarction. American Journal of Physiology – Heart
and Circulatory Physiology, 298(5):H1415-1425.
Thomas, S., Lewis, S., Hyde, J., Castle, D.J. & Komesaroff, P.A. (2010). The solution needs to be complex: Obese adults’
attitudes about the effectiveness of individual and population based interventions for obesity. BMC Public Health, 10:420.
Thomas, S.L., Karunaratne, A., Castle, D., Hyde, J. & Komesaroff, P. (2010). ‘Just Bloody Fat!’ A qualitative study of body
image, self esteem and coping in obese adults. International Journal of Mental Health Promotion, 12:39-49.
Wielandts, J.Y., De Buck, S., Ector, J., La Gerche, A., Willems, R., Bosmans, H. & Heidbüchel, H. (2010).Three-dimensional
cardiac rotational angiography: Effective radiation dose and image quality implications. Europace, 12(2):194-201.
Yuen, D.A., Connelly, K.A., Advani, A., Liao, C., Kuliszewski, M., Trogadis, J., Thai,K., Advani, S.L., Zhang, M., Kelly,
D.J., Leong-Poi, H., Keating, A., Marsden, P.A., Stewart, D.J. & Gilbert, R.E. (2010). Culture-modified bone marrow
cells attenuate cardiorenal injury in chronic kidney disease via an antifibrotic mechanism. PLoS One, 5(3):e9543.
CvRC Annual Report 2010-2011
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© Cardiovascular Research Centre 2011
CvRC Annual Report 2010-2011
Covering November 2010 – December 2011
Including images courtesy of St Vincent’s Hospital Melbourne.
Cardiovascular Research Centre:
Faculty of Health Sciences, Australian Catholic University
in collaboration with St Vincent’s Hospital Melbourne
and the University of Melbourne
CvRC thanks Mrs Estibeiro-Rathod, Ms Puchalski and Ms Spano for establishing this report.
For further information please visit: www.cvrc.edu.au
Cardiovascular Research Centre
VECCI Building
4/486 Albert Street
East Melbourne VIC 3003
Australian Catholic University
ABN 15 050 192 660
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