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C ARDIMAX
CLINICAL APPLICATIONS
• Multidimensional Support for Cardiovascular Health
• Increases Cardiac Output and Promotes Healthy Blood Flow
• Supports Healthy Energy Levels
C AR D I O VA S C UL A R HE A LTH
Cardimax contains a targeted blend of nutrients to support
strong cardiovascular function and output. It provides a
well-rounded, broad spectrum approach to supporting
healthy blood pressure levels, increasing cardiac output,
blood flow, antioxidant levels and cardiac energy levels. Two
capsules of Cardimax contain 500 mg L-carnitine tartrate,
500 mg taurine, 200 mg hawthorne extract and 150 mg
quercetin.
Overview
Optimal cardiovascular wellness depends upon a healthy
cardiovascular system and the vascular system of the brain,
kidneys and peripheral arteries. With aging, a number of
physiological and morphological changes occur and many
individuals require extra support. Cardimax provides several
key ingredients to support cardiovascular health. Hawthorne
extract and taurine, support cardiac output, promote healthy
blood flow and help maintain healthy blood pressure levels;
L-carnitine supports healthy energy levels. and promotes
cardiovascular health. Quercetin supports normal levels of
inflammation and blood vessel function.
Hawthorn Leaf & Flower Extract†
Herbalists have used hawthorn extract for centuries to support
cardiovascular wellness and promote the contractile force
of the heart. Its efficacy and safety have been confirmed in
human clinical trials. Hawthorn has been shown to support
healthy blood pressure, coronary blood flow and cardiac
rhythm.[1] A double-blind, randomized clinical study (using
two 50 mg tablets of hawthorn leaf and flower extract, three
times daily) found that exercise among the study group
increased exercise tolerance and output, compared to the
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
placebo group. This study group also experienced better
maintenance of healthy systolic blood pressure levels, both at
rest and during maximum exercise.[2]
L-Carnitine†
The role of L-carnitine is to transport long-chain fatty acids across
the mitochondrial membranes to enhance energy production
in the form of ATP. One study (L-carnitine administered to 30
patients at a dose of 50 mg/kg/day) found that L-carnitine
helped support healthy diastolic blood pressure after six
months in 20 of the patients. It also enhanced cardiac output,
thereby increasing circulation, tissue oxygenation and energy
production.[3] In this way, L-carnitine has been shown to boost
cardiovascular performance and preserve heart muscle
tissue.[4]A recent 2013 meta-analysis of 13 studies concluded
that L-carnitine clearly promotes positive cardiovascular
outcomes, compared to placebo.[5]
Taurine†
A non-protein amino acid, taurine is the primary free
intracellular amino acid in many tissues throughout the body.
It is known to help balance calcium and potassium in muscle
cells, a critical function to help the heart muscle operate as
an efficient pump. Taurine has been found to have beneficial
effects on mitochondrial health, promoting greater energy
production in the heart.[6] Human studies on both taurine
and L-carnitine have achieved significant clinical results. In
a double-blind, randomized, crossover study of 14 patients,
those who received the taurine treatment had improved
markers of cardiovascular and pulmonary health.[7] In another
study, a does of 3 g of taurine a day was found to significantly
enhance systolic left ventricular function after only six weeks.[8]
Quercetin†
References
Quercetin, one of the most well researched and established
plant bioflavonoids, has been shown to have significant
benefits for cardiovascular health. These benefits are directly
related to quercetin’s function as an antioxidant promoting
healthy blood vessels. Quercetin has long been known to
support cardiovascular health and to support normal levels of
inflammation. In an animal study using 10mg/kg of quercetin
for 4 weeks, those receiving quercetin had a significant
promotion of healthy systolic blood pressure levels.[9] Among
healthy men who received a quercetin-rich supplement
and were examined for blood vessel function, a significant
enhancement of post-prandial blood vessel function was
achieved.[10]
1.
Mills S and Bone K. Hawthorn (Crataegus spp.). 2000;439447.
2.
Barrett M. Hawthorn. 2004;809-841.
3.
El-Beshlawy, A., Ragab, L. et al. Improvement of cardiac
function in thalassemia major treated with L-carnitine.
Acta Haematol. 2004; 111(3):143-148.
4. Vescovo, G., Ravara, B. et al. Inflammation and perturbation
of the l-carnitine system in heart failure. Eur J Heart Fail.
2005; 7(6):997-1002.
5.
DiNicolantonio JJ, Lavie CJ, Fares H, Menezes AR, O’Keefe
JH. L-carnitine in the secondary prevention of
cardiovascular disease: systematic review and metaanalysis. Mayo Clin Proc. 2013 Jun;88(6):544-51.
6.
Yang Y, Zhang Y, Liu X, Zuo J, Wang K, Liu W, Ge J.
Exogenous taurine attenuates mitochondrial oxidative
stress and endoplasmic reticulum stress in rat
cardiomyocytes. Acta Biochim Biophys Sin (Shanghai). 2013
May;45(5):359-67.
7.
Azuma, J., Sawamura, A. et al. Therapeutic effect of taurine
in congestive heart failure: a double-blind crossover trial.
Clin Cardiol. 1985; 8(5):276-282.
8.
Azuma, J., Sawamura, A. et al. Usefulness of taurine in
chronic congestive heart failure and its prospective
application. Jpn Circ J. 1992; 56(1):95-99.
9.
Machha, A. and Mustafa, M. R. Chronic treatment with
flavonoids prevents endothelial dysfunction in
spontaneously hypertensive rat aorta. J Cardiovasc
Pharmacol. 2005; 46(1):36-40.
Directions
2 capsules two times per day or as recommended by your
health care professional.
Does Not Contain
Gluten, corn, yeast, artificial colors and flavors.
Cautions
Do not consume this product if you are pregnant or nursing.
Consult your physician for further information.
Supplement Facts
V4
Serving Size 2 Capsules
Servings Per Container 60
2 capsules contain
Amount Per
Serving
L-Carnitine L-Tartrate
500 mg
Taurine
500 mg
Hawthorn Leaf and Flower Extract
200 mg
(Standardized to contain 1.8% Vitexin-2 Rhamnoside
and Hyperoside)
Quercetin Dihydrate
150 mg
% Daily
Value
*
*
*
*
* Daily Value not established
ID# 507120 120 Capsules
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
10. Nakayama H, Tsuge N, Sawada H, Higashi Y. Chronic
intake of onion extract containing quercetin improved
postprandial endothelial dysfunction in healthy men. J Am
Coll Nutr. 2013;32(3):160-4.