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Teaching Notes Enlarged Heart Determining heart-to-chest ratios Background Suggested Grades Basic measurements are an integral part of making medical diagnoses. In this activity, students measure chest x-rays of six patients. They calculate the heart-to-chest ratio and determine whether each patient has an enlarged heart. Because the measurements are simple but subjective, this activity offers an excellent opportunity for exploring measurement reliability and validity. As with any medical image, the first thing students should do when looking at a chest x-ray is determine the orientation and identify major anatomical landmarks. A diagram is provided to help the students with this process. An anatomy or biology text would also be useful in identifying structures. clavicle scapula lung aortic arch ribs heart liver Goal Students will diagnose cardiomegaly by identifying anatomical structures in patient chest x-rays and calculating heart-to-chest ratios. Topics chest x-ray anatomy humerus • 7–12 diaphragm X-rays vary in quality. Using image processing, students can enhance the x-ray images to better visualize the heart shadow and chest cavity. Students measure the width of the widest part of the heart, and then the width of the widest part of the chest cavity. From these data, they calculate a heart-to-chest ratio. Ratios greater than 0.5 indicate an enlarged heart. • Humans • Anatomy • Circulatory system Biology Strands • Functional Units & Organization • Diversity & Evolution Science Skills • Observation • Cooperation & Communication • Quantification of Data • Organization of Data • Data Analysis Technology • X-ray imaging IPTechnique Sheets maximum width of heart shadow • Look-up Tables • Selecting • Measuring maximum width of chest cavity Identifying the maximum widths of the heart and chest is subjective. For this reason, students remeasure one of the patient x-rays, and compare their answers to their original measurement. It is likely that students’ results will be quite different the second time around. The last section of the activity, called Need a second opinion?, requires students to consult with one another on their measurements. This provides an opportunity for students to see how the same data are interpreted differently by © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Enlarged Heart 65 each person or group. (If you only have one computer, time is limited, or students are working alone, this section can be left out of the classroom activity.) After students have finished the first part of the activity, bring the class together to determine what the high and low ratios were for each patient. This section of Enlarged Heart provides a foundation for discussing the cooperative nature of scientific inquiry, as well as the issues of reliability and validity in measurements. Biology Objectives The student will: • observe and interpret chest X-rays • use heart-to-chest ratios to diagnose patients with cardiomegaly Curricular Context Prerequisites • Students need a background in simple human anatomy, particularly the heart and lungs. An anatomy reference book will be useful. • Students should be able to calculate ratios. Related Activities • Medical Imaging: X-ray vs. MRI is a good introduction to medical imaging technology and is a useful prerequisite for this activity. • This activity complements Enlarged Heart Cells because enlarged cells are one cause of cardiomegaly. • Articles from periodicals such as “The Hearty Fisherman” by Tony Dajer in Discover magazine, July 1992, pp. 80–82, relate real-life scenarios to the science content in this lesson. Integration • Health Heart disease • Mathematics Ratios, linear measurements Acknowledgments Activity developed by Denice Warren and Deborah Nead, Image Processing for Teaching project, University of Arizona, Tucson, Arizona, and Loretta Milligan, Heizer Jr. High School, Hobbs, New Mexico. Images courtesy of Dr. Timothy Hunter, Department of Radiology, University Medical Center, Tucson, Arizona. References Milne, E. N. C., and M. Pistolesi. Reading the Chest Radiograph: A Physiologic Approach. St. Louis: Mosby, 1993. 66 HIP BIOLOGY 2 © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Answers 1–3. Patient Maximum width of heart Maximum width of chest Heart-tochest ratio Diagnosis Bill 83 213 0.39 normal heart size Fran 110 185 0.60 cardiomegaly Gary 82 236 0.35 normal heart size Jill 77 156 0.49 normal heart size Oliver 90 235 0.41 normal heart size Paul 113 193 0.59 cardiomegaly 4. Answer will most likely be different from Fran’s measurements in the table above. 5. The answers changed after re-measuring Fran because it is difficult to measure exactly the same place on the x-ray each time. 6. Answers to this question depend on the class interactions. Students should find that there is tremendous variability in answers and that remeasuring a patient and consulting with other students raises their confidence in their answers. 7–8. Answers will vary based on class measurements. Fran and Paul both have heartto-chest ratios of greater than 0.50, therefore they have cardiomegaly. Jill has a borderline ratio, but she is rather thin, so her ratio may be high because her chest cavity is narrow. 9. It is important for doctors to consult with other professionals because this makes their diagnoses more reliable. Consulting reduces the chance for mistakes a single doctor might make when evaluating a patient. © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Enlarged Heart 67 68 HIP BIOLOGY 2 © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Lesson Enlarged Heart Determining heart-to-chest ratios Infections, poisoning, trauma, or heart failure can cause a heart to enlarge. This condition is called cardiomegaly, and can develop either suddenly or gradually. Cardiomegaly may be caused by an increase in the size of the muscle itself, a buildup of fluid around the heart, or more blood flowing through the heart. In Greek, cardio = heart megaly = large Reading an x-ray ì Open the chest x-ray images Bill and Bill’s Anatomy. Â File/Open… Doctors often use x-rays such as these to determine the size of a patient’s heart. The heart appears as a dark shadow on an x-ray, and the chest cavity surrounding the heart appears lighter. Take a moment to carefully observe and try to identify any key parts you may see. Compare your observations to the diagram of Bill’s Anatomy. People come in different sizes, and so do their hearts. To determine if a heart is abnormally large, doctors calculate the ratio of the width of the heart to the width of the chest cavity. Heart-to-chest ratios below 0.50 are considered normal by doctors. In this activity, you will examine chest x-rays of six patients for cardiomegaly. 1. On the Data Sheet, fill in the table with the names of the patients and record your measurements as you go. ì Enhance the Bill x-ray so you can see the heart better. ì Use the ‡ selection tool to make a line across the widest part of the heart. Identifying the place to measure may be difficult—try to be consistent. ì Measure and record the width, in pixels, of the widest part of the heart. ì Use the same technique to select, measure, and record the width of the widest part of the chest cavity. 2. Calculate the heart-to-chest ratio in decimal form for Bill. ì Open the other x-rays, and repeat your measurements for each one. Record your measurements in the data table and calculate the heartto-chest ratio for each patient. ○ ○ ○ ○ ○ ○ ○ ○ maximum width of heart shadow maximum width of chest cavity ○ ○ ○ ○ See the Selecting and Measuring IPTechnique Sheets. Â Process/Equalize or adjust the ¬ and Æ sliders in the Map window. Â Analyze/Measure then Analyze/Show Results heart - to - chest ratio = max. width of heart max. width of chest cavity 3. Which patients have cardiomegaly? Record your diagnoses. Need a second opinion? ì Without looking at your previous measurements, remeasure Fran’s x-ray. 4. Enter Fran’s newest measurements in the table on the Data Sheet and calculate her heart-to-chest ratio based on these values. © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Enlarged Heart 69 5. Why were your answers different from the first time you measured Fran’s x-ray? Because you must decide where to measure the widths of the heart and chest cavity, your answers depend on how you interpret the x-ray. You may interpret an x-ray differently than one of your classmates, or you may even interpret the same x-ray differently each time you look at it. That’s why interpretations can introduce error into a measurement. Doctors often rely on other medical professionals for second opinions. In this section, you will consult with your classmates to compare both your measurements and your diagnoses. 6. In your class, what were the highest and lowest heart-to-chest ratios for each patient? Record these values in the table on your Data Sheet. 7. Based on the class’s highest ratios, which patients have cardiomegaly? 8. Based on the class’s lowest ratios, which patients have cardiomegaly? 9. Why should you get a second opinion from a doctor on a diagnosis? Relate your answer to what you have just learned from this activity. Further Exploration • Measure the area of the heart and chest cavity and determine the heartto-chest ratio using area measurements. Is this ratio also diagnostic of cardiomegaly? Â Use the fi tool. See the IPTechnique Sheets on Selecting and Measuring. • Nurses often put catheters into a patient’s vein to make it easier to give medicine and to draw blood. Look at Paul’s x-ray. Note the catheter wire on the upper right side of the image. How many others can you find in this image? catheter – a tube inserted in a vein so the patient doesn’t have to be poked every time medication is needed. • In Oliver’s x-ray, look for the dark mass in his right lung. This is a tube that was inserted into his collapsed lung. What function might this tube serve? 70 HIP BIOLOGY 2 © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Enlarged Heart Name(s) Data Sheet Class Date 1. Fill in the table below with the names of the patients. Record your measurements as you go. Patient Maximum width of heart Maximum width of chest Heart-to-chest ratio Diagnosis 2. Calculate the heart-to-chest ratio in decimal form for Bill. Show your work in the space provided, and enter the results in the table above. 3. Which patients have cardiomegaly? Record your diagnoses in the table above. 4. Enter Fran’s newest measurements in the table below, and calculate her heart-to-chest ratio based on these values. Remeasurement of Fran’s x-ray Patient Maximum width of heart Maximum width of chest Heart-to-chest ratio Diagnosis 5. Why were your answers different from the first time you measured Fran’s x-ray? © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work. Enlarged Heart 71 6. In your class, what were the highest and lowest heart-to-chest ratios for each patient? Record these values below. Patient Highest ratio in class Lowest ratio in class 7. Based on the class’s highest ratios, which patients have cardiomegaly? 8. Based on the class’s lowest ratios, which patients have cardiomegaly? 9. Why should you get a second opinion from a doctor on a diagnosis? Relate your answer to what you have just learned from this activity. 72 HIP BIOLOGY 2 © 1996 Arizona Board of Regents. Limited classroom reproduction rights are granted under the notice appearing earlier in this work.