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7 Pune, September 26, 2010 Changing lifestyles and decreasing physical activities are posing greater risks of heart attacks, but nearly 76 percent people have never done a cardiac check to assess the hazard they face. A s the World Heart Day is being observed Sunday, findings of a survey reveal that nearly 60 percent of people between the ages 20 and 65 don't feel they have any risk of heart attack, even though nearly 20 percent already have a family history. The survey shows that people in the 20-30 age group were the most optimistic about not developing heart diseases even though a majority of them have never got a heart checkup done. However, doctors say that with changing lifestyle, three times rise has been registered in heart diseases among youths, which include coronary heart disease, heart failure and stroke. As a result of changing lifestyle, the average age at which a person may suffer a heart attack has come down from 40 years to 30 years. It's a matter of great concern for India, sedentary lifestyle, hectic schedules, no physical activity, and smoking and drinking habits are the factors leading to heart diseases among youths,' he adds. According to the World Health Organisation (WHO), cardiovascular diseases are the world's largest killers, claiming 17.1 million lives a year. Negligence towards the risk has been dubbed by doctors as one of the biggest reasons behind the rapid growth in the number of cardiac diseases cases. The theme this year is 'Workplace Wellness Take Responsibility for your own Heart Health, focusing on the need to generate awareness. Doctors agree that emphasis is now needed on the preventive measures. In a country like India where we have different kinds of food habits and very negligible percentage of the population performing daily exercises, we need to stress more on the preventive aspect of cardiac ailments. In addition to the stressful life, obesity, diabetes and smoking add to the risk. World Heart Day that is celebrated on the last Sunday of September every year was first celebrated in the year 1999 with an aim to promote wellness of heart. Today it is celebrated in more than 100 countries and by many people including cardiologists, hospitals and non medical professionals as well. As estimated by the World Health Organisation (WHO), cardiovascular diseases remain the world's largest killers, claiming 17.1 million lives per year. With this year's themeWorkplace wellness, World heart day will be celebrated by focusing on young professionals' health including IT, corporates, and many more. The theme that rightly mentions workplace wellness will help youth to understand the importance of healthy behaviours and lifestyle because cardiovascular illnesses that was best known as the ageing disease is nowadays gripping many young professionals. Heart problems are more commonly seen nowadays Listen to your Heart ...was what Dr JS Dugal, Head of Cathlab Jehangir Hospital, had to say when asked about what he would like people to do on World Heart Day. Your heart may be sending you signals that you should heed. Very often we neglect the radiating pain in the hands and shoulders, breathlessness, profuse sweating on exertion, chronic, unresolving pain in the stomach. When these symptoms persist and do not resolve it is better to consult your Physician or, even better, get a heart check done. When asked who should take extra care of their heart Dr Dugal had this to say. According to him, Diabetes and Hypertension are the first stages on the highway to Heart Attack. Those who suffer from these ailments, or even if they have a history in the family, must take extra care of their heart. Obviously those with a history of heart disease in the family. Nowadays there is a significant number of young patients with advanced heart disease. Poor Lifestyle, stressful lives and sedentary habits are responsible factors in these cases. Dr Dugal gave the example of a 40 year old with 2 major and total blocks on whom, they had recently done a complex angioplasty during a cardiac workshop that was transmitted live to an audience of international Cardiologists at Amsterdam. Women are naturally protected from Heart disease until menopause. Thereafter their natural protection diminishes and they need to take care of their hearts. Today we have recourse to new blood tests that can tell us about the levels of markers like Homocystein, Apolipoprotein, Lipoprotein, from which we can accurately estimate your risk for heart disease. Advanced imaging like the CT Angio allows us to literally look into your heart and check for blockages and other problems that are not apparent. Since these are expensive investigations we have made special discounted heart check packages, which are affordable and will help you protect your future, he added. among people between 20 and 35 years of age and has become a serious problem that needs immediate attention and which is why this theme. The rise of cardiovascular problems among youth can be attributed to major reasons and risk factors like sedentary lifestyle, bad eating behaviour, smoking, alcohol intake, unusual sleeping hours, inadequate intake of fruits/vegetables, obesity and lack of exercise. Wellness at workplace has become the priority that will not only help the organisation going but will also benefit the employee by reducing his/her absenteeism to work. Wellness at workplace has become the priority that will not only help the organisation going but will also benefit the employee by reducing his/her absenteeism to work. To keep the employees stress free and away from cardiac ailments healthy lifestyle can be adopted at the workplace like eating right, keeping away from alcohol and tobacco. Blessing and a Ray of Hope For Heart Patients he heart muscles are deficient of blood supply and oxygen due to blockages in coronary - the heart's blood supplying arteries which cry, needs attention before the patient gets a massive heart attack and at times even death. Every fourth person who gets a heart attack dies before he reaches the hospital - The World Health Organisation in its recent report have indicated that 60% of the worlds deaths arising out of heart attacks are going to be from India. It is there fore important to understand this disease and take alternative measures by increasing blood supply to the heart before it is damaged severely and the Heart Transplant is the only solution. In light of this Global Heart Foundation has an excellent and easy solution to solve this problem called EECP - Enhanced External Counter Pulsation. EECP is a US FDA approved treatment and recognised by cardiologists all over the world. With the help of this US made machine, new collateral blood vessels to the heart are opened up, hence increasing the blood flow to the heart and in turn make the heart stronger. (It is like addition of a new army). The heart is a pump which supplies blood to each part of the body by positive pressure. When the heart receives blood from the various parts of the body there are no pumps, it is by negative pressure that this blood is received, and thus T this blood does not flow through the small blood vessels, nor are the collaterals open . In this EECP technique cuffs are tied to the legs and thighs which are rhythmically deflated and inflated during systole and diastole - which is the pumping out and pumping in of the blood into the heart. During this filling phase or pumping in phase EECP pushes Venus blood towards the heart by positive pressure with the effect that blood starts flowing through these multiple tiny vessels (which are abundant in the heart) and thereon opens collateral not only in the heart but the entire body. Since this treatment is given one hour at a time for 35 hours these blood vessels remain open for many years to come. This could be called as "Natural Bypass" - without surgery. This treatment is use full in intractable angina, for patients who want to avoid heart bypass surgery, angioplasty, patients who have diffused coronary arterial disease, patients who don't want to repeat cost- ly & risky procedures due to re blockages or due to recurrences - i.e. 2nd time angioplasty or heart bypass surgeries - which may cost in lacs of rupees, heart failure patients, patients whose ejection fraction is less than 35%, acute myocardial infarction patients. The effect of this treatment could be assessed on well recognised stress thallium test. There is a remarkable reduction in angina, significant improvement in exercises capacity, improves functional status and gives a better quality of life for the patients. When the heart failure is ischaemic or non ischaemic this treatment reduces the admission in ICCU as emergency and prevents major heart attack episodes. This treatment also reduces cardiac after load drastically and peak oxygen intake is improved. International EECP registry has documented the results and benefits of this treatment irrespective of age, ventricular function and diabetes is no bar for this treatment . This treatment has a staunch record of being very safe and effective non-invasive and also a cheap & affordable treatment. For more information you may log on to www.globalheartfoundation.org —Dr. Sharadchandra Deshpande Sr. Medical Director - Global Heart Foundation. Mob: 9850277773 Email: [email protected] LIVING WITH HYPERTENSION Hypertension today afflicts a large section of population who may or may not be aware of it. Hypertension means a sustained rise in blood pressure above the normal -120 Systolic and 80 Diastolic. Hypertension is a chronic condition for which one has to take medicines life long. If left unmanaged, hypertension can be a silent killer-it can be fatal as it may damage kidneys, eyes and can lead to stroke or heart attack. How does one live with Hypertension? Should high blood pressure affect life-style? The answer is NO…if it is managed well. It is not very difficult. One needs a certain discipline in life and then can a good quality life. But for this, one should remember the following: > Regular check-ups ---Keep BP below 120/80 > Take medicines regularly > Regular exercise- brisk walk for at least 30 minutes daily > Reduce stress > Enjoy your work > Develop a hobby > Maintain a healthy weight-Don't let a paunch show - it is unhealthy. > Eat well balanced diet- less of fats and NO junk food. > Reduce salt intake > Don't smoke. Let's accept it. Hypertension needs to be managed. And management is in our hand. I too am a hypertensive for many years. Yet I work hard and late hours too, do Gym, take long flights and travel extensively. I manage my blood pressure well. You too can do that. And live a good quality life. —Arun Khanna-COO, Emcure Pharma Classifieds INITIATIVE BY DNA CLASSIFIEDS ON WORLD HEART DAY Mumbai, September 26, 2010 8 HEART ATTACKS - Prevention and early treatment is the key to success H eart disease is the single largest cause of death in India with heart attacks being accountable for one third of all deaths caused by heart diseases. In India, the incidence of heart disease has doubled during the last 20 years due to the changes in economic development and lifestyle modifications. In comparison to the west, the disease is affecting us at a younger age. The rate of heart attacks among Indians younger than 40 years of age in the last few years was five times higher compared to other populations. The recent statistics show that one out of ten heart attacks happen before the age of 35. Ischemic heart disease is increased oxygen demands during exercise, walking or any other physical activity. This results into severe pain in the chest region which may radiate to left arm. This is known as angina pectoris (Angina = pain; pectoris = chest in Latin) The pain of angina is usually temporary and is relieved by rest or by taking a tablet of glyceryl trinitrate or sorbitrate (drug that expands the coronary arteries). However, at times there may be rupture of the cholesterol plaque which then gets superimposed with blood clot. This may result into sudden and complete block of the coronary vessel. When there is no adequate oxygen, the muscle starts dying. The death of heart tissue as a re- definitely reduce the risk of heart diseases. Symptoms of heart attack: The symptoms of a heart attack vary from one person to another. They can range from a severe pain in the centre of the chest, to having mild chest discomfort. Classic symptoms of a heart attack may include chest pain associated with shortness of breath, profuse sweating and nausea. The chest pain may be described as tightness, fullness, a pressure, or an ache. Unfortunately, many people do not have these classic signs. Other presentations of heart attack may include indigestion, jaw ache, pain only in the shoulders or arms, short- ness of breath, or nausea /vomiting or dizziness. This list is not complete, since many times people can experience a heart attack with minimal symptoms. In women and the elderly, heart attack symptoms can be atypical and sometimes so vague as to be easily missed. The only complaint may be extreme weakness or fatigue. In diabetics, there may not be any pain at all as result of affection of nerves due to diabetes (Silent myocardial infarction). Hence immediate medical help is mandatory. Many people die before they present for medical care because they ignore their symptoms. The diagnosis of myocardial infarction will be confirmed by the doctor after taking an electrocardiogram. When to call for medical help? Any chest pain should be treated as medical emergency, as classic symptoms of heart attack may not occur in all. Time = Muscle : Although biochemical and functional abnormalities as well as severe loss of heart contractility begin immediately following coronary obstruction; it takes about 2040 minutes for irreversible muscle injury to occur. Prompt treatment and recanalisation of coronary arteries can minimize the size of the infarction, preserve cardiac functioning and minimize the risk of death. Early treatment reduces the size of scar tissue and reduces further complications like heart failure, life threatening arrhythmia (abnormality of the heart rhythm and cardiac arrest (sudden stoppage of cardiac beating that often results in to death). WORLD HEART DAY H as a result of inadequate blood supply to the heart muscles (Ischemia - lack of blood supply). The major forms of heart diseases are myocardial infarction, angina pectoris and congestive cardiac failure. Heart is made up of cardiac muscles which require continuous blood flow to provide oxygen supply that allows it to work. Heart muscle gets the blood supply from coronary arteries. Left anterior descending coronary artery is the artery that supplies majority of the left ventricle. The commonest cause of heart disease is narrowing of coronary arteries as a result of cholesterol plaque. A cholesterol plaque narrows coronary vessels and restricts the amount of blood flow. The blood flow in a narrowed coronary artery may be enough for the heart muscles to work at rest, but may not be adequate to meet the sult of prolonged ischemia (lack of blood supply) is termed as "myocardial infarction" (myo=muscle +cardial=heart) Infarction=death due to lack of oxygen. The heart muscle does not regenerate and so even if the patient survives an attack, he or she will have to live with a portion of their heart being non functional and complications resulting from the same. Risk factors for heart attack: Ischemic heart diseases are mainly as a result of deposition of cholesterol plaque into the coronary arteries (also known as atherosclerosis). The risk factors for ischemic heart disease include: family history, hypertension, diabetes, high cholesterol levels and smoking. Majority of these conditions are as a result of stress, obesity, lack of exercise, unhealthy eating habits which if prevented can By Dr. P. Bhandari, MD based on article authored by Dr. Sameer Mehta, MD, FACC,MBA, Interventional Cardiologist, Associate Professor of Medicine, University of Miami published in the Indian Heart Journal special issue (Sept-Oct 2009) stroke. A heart-healthy workplace encourages a healthy diet, physical activity and a smokefree environment. Further, almost half of the deaths due to chronic diseases occur in the productive age group (15-69 yrs). A healthy workforce can result into increased productivity, loss of absenteeism, enhanced staff retention and lowered medical cost. At this 10-year milestone, the World Heart Federation is urging governments, healthcare professionals, employers and individuals to reduce the burden of heart disease and stroke. On occasion of the World Heart Day, several activities are organized worldwide by member and non-member organizations. The World Heart Federation would be launching a global cardiovascular disease 10-year report card in partnership with the World Health Organization and the World Economic Forum as well as would take comparative survey of heart-healthy occupations. The activities in India would involve social media (Youtube, Twitter, Facebook, etc.), conference/seminars to healthcare,walks, walkathon, exhibitions, press activities, competitions, awareness surveys and public awareness seminars. On this World Heart Day, everyone is called upon to take responsibility for their own heart health and say "I work with Heart". World Heart Federation © Jason Joyce eart attacks and strokes have emerged as major killers in developed as well as developing countries killing 17.1 million lives a year. They are of a great concern to medical community and society in general. Over 80% of cardiovascular disease deaths take place in low-and middle-income countries. Tobacco use, an unhealthy diet, physical inactivity and harmful use of alcohol increase the risk of heart attacks and strokes. Since the year 2000, World Heart Day has been organized by World Heart Federation in participation with World Health Organization (WHO) supported by several member and non-member organizations worldwide. The aim of this activity is to disseminate the message that at least 80% of premature deaths results from heart disease and stroke could be avoided if the main risk factors, tobacco, unhealthy diet and physical inactivity, are controlled. It is organized worldwide on the last Sunday of September every year. This year, 26th September 2010 is World Heart Day. Workplace Wellness The theme for this year's World Heart Day is "workplace wellness". Over half of our waking hours are spend working, the workplace is ideal to promote heart-healthy messages and raise awareness about the risk factors for heart disease and Take responsibility for your own heart health Ten simple tips to keep your heart healthy > Healthy food intake - Eat at least 5 servings of fruit and vegetables a day and avoid saturated fat and processed foods. > Get active & take heart - 30 minutes of activity each day > Say no to tobacco - Risk of coronary heart disease will be halved within a year and will return to a normal level over time. > Maintain a healthy weight - Weight loss, with lowered salt intake, leads to lower blood pressure, a major risk factor for stroke and heart disease. > Know your numbers - Visit a healthcare professional who can measure your blood pressure, cholesterol and glucose levels, together with waist-to-hip ratio and body mass index (BMI). Once you know your overall risk, you can develop a specific plan of action to improve your heart health. > Limit your alcohol intake - Excessive alcohol intake can cause your blood pressure to rise and your weight to increase. > Insist on a smoke-free environment - Demand a tobacco ban - ensure your workplace is 100% smoke-free. > Bring exercise to the workplace - Include physical activity in your working schedule cycle to work if this is possible, take the stairs, exercise or go for a walk during your lunch breaks, and encourage others to do so too. > Choose healthy food options- Ask for healthy food at your work canteen, or find nearby cafes or restaurants that serve healthy meals. > Encourage stress-free moments -whilst stress has not been shown to be a direct risk fact or for heart disease and stroke, it is related to smoking, excessive drinking and unhealthy eating, which are risk factors for heart disease. Take time for lunch away from your workplace to get some fresh air. Have regular breaks during the day - try stretching or exercising for 5 minutes twice a day. Control Hypertension H is a major risk factor and better control can lead to prevention of 300,000 of the 1.5 million annual deaths from cardiovascular diseases in India. What is Normal BP? Blood pressure is measured with a help of an instrument called sphygmomanometer. Systolic BP is the pressure in hirality is the science of similar looking components of a molecule whose mirror images are not super-imposable. These similar but not super-imposable parts do not behave similarly in the body. Hence the two versions of the same molecule may differ in efficacy and safety. Chirally pure products are just one of these two forms that are 'purified' to give only one form with known, sure and precise action and safety. The unique advantages of these pure molecules are that they require almost half the dose to produce equal decrease in blood pressure, exert less metabolic load on the body and also have a favourable side effect profile and have less chances of interacting with other drugs. For further information on please browse www.chiralemcure.com. C arteries when the heart is pumping blood and diastolic BP is the pressure when heart is getting filled with blood. The normal upper limits for systolic and diastolic blood pressure are 120 mm of Hg and 80 mm of Hg respectively. A person is termed as hypertensive if he has elevated systolic > 140 mm Hg and/ or diastolic BP > 90 mm of Hg two or more times during sitting or lying down position. Risk factors for hypertension: Many factors affect blood pressure in our body including salt intake, status of nervous system, kidneys or blood vessels, also levels of different body hormones. About 90% cases of hypertension are not associated with any major illness in the body and are termed as primary or essential hypertension. Only 10% of the hypertensive cases result due to kidney, endocrine, heart and other problems. Although no direct cause has identified itself, there are many factors which contribute to the development of essential hypertension: Increased age, family history, In a heart attack the treatment is to ensure blood supply (Reperfusion) to the myocardium at the earliest. 1. Administration of clot-busting agents (thrombolytics) The most common method adopted is the use of thrombolytic agents as they are simple and easy to administer. It can be administered in a well equipped (Cardiac) ambulance or a nursing home with ICU facilities and ensure that patient gets the right treatment on right time and save the precious time as Time=Muscle. According to the recent recommendations, thrombolysis should be performed within 30 minutes of onset of chest pain for best results. Till recently, the agents available in our country could be administered completely in an hour or more only. They produce some undesirable side effects (allergic reactions). 2. Elaxim in Heart Attacks All these issues have been addressed by the path-breaking work done in bio-engineering at Pune by the introduction of Tenecteplase (Elaxim), by Gennova Biopharmaceuticals, a 100% owned subsidiary of Emcure Pharmaceuticals Ltd, Pune. This revolutionary agent has been available in the world market for about seven to eight years, now. This medicine is the most widely used agent in the United States for Thrombolysis (breaking up a clot). Tenecteplase can be administered in a matter of seconds (5-10) easily as a single injection. The treatment can be administered even at the home of the patient, in an ambulance (Pre-Hospital) or a Nursing home with ICU facilities. This medicine offers the best results when compared to the existing agents, has the least incidence of side effects and is the easiest agent to administer. This is very important in small towns and villages of India, where cath-lab facility may not be available immediately Studies have shown that this agent offers results comparable to Angioplasty when administered within 2-3 hrs of an attack. Elaxim is now available at approximately 800 centers across the country. Elaxim has been administered in nearly 16000 patients, and has saved thousands of lives . A recently presented study in the Indian Heart Journal shows that Elaxim has a success rate of more than 85% in Indian heart attack patients. One of the emerging modalities is the Pharmaco-invasive management (Angioplasty following thrombolysis) is a better, safer option than Primary Angioplasty. 3. Coronary angioplasty In angioplasty, a catheter containing a balloon is passed into the coronary vessel in order to remove the obstruction. This is usually accompanied with fitting of a stent (a scaffold to maintain the artery in an open state) at the site of occlusion. Coronary angioplasty should be performed within 90 minutes of onset of chest pain for best results. But this method is expensive ,time consuming and has to be performed in a tertiary care hospital (Hospital with a Cath Lab) only, by a skilled cardiologist. In today's scenario with ever increasing traffic congestions, patients reaching hospital on time and receiving the right treatment is a point of concern. Can heart attacks be prevented? To prevent heart attacks or other heart diseases, it is important to make changes in the lifestyle, and live a healthy life. It is essential to maintain a good control of hypertension, diabetes and cholesterol levels. Undergoing medical check-ups regularly is equally important. For any further information please browse: www.heartattackelaxim.com www.elaxim.co.in C. Venkata S. Ram, MD, MACP, FACC is the director of the Clinical Research Institute of Dallas Nephrology Associates. In addition to his consultative practice, Dr. Ram is a professor of Internal Medicine at the University of Texas Southwestern Medical Center at Dallas and he is the director of the Texas Blood Pressure Institute. PREVENT STROKE AND HEART ATTACKS ypertension commonly termed as high BP is a medical condition where the arterial blood pressure remains persistently elevated. Cases of hypertension are increasing rapidly among Indian urban populations and more than two-fifths of the Indian urban adult population has hypertension. High blood pressure (BP) Treatment Options For Heart Attacks creases the risk of development of heart failure. sedentary lifestyle, stress, obesity (especially around the abdomen), increased salt intake, presence of diabetes, high cholesterol levels, smoking. Symptoms of hypertension: Usually mild to moderate hypertension is not associated with any symptoms. But sudden rise of BP may be associated with headache, drowsiness, confusion, vision disorders, nausea, and vomiting. Why should hypertension be treated? Untreated hypertension results into several complications. There could be sudden rise in the blood pressure and it may result into sudden stroke due to bleeding inside the brain tissue. Long term hypertension causes damage to arterial wall and results into development of atherosclerotic plaques. These plaques can cause occlusion of heart, kidney and brain vessels. Thus untreated hypertension increases the risk for heart attacks and strokes due to clotting in the brain vessels. Long term hypertension induces abnormalities in the kidney function and can lead to kidney failure. Hypertension also causes excess load on the heart and in- Treatment of hypertension: There are several medications proven useful in the treatment of hypertension including beta blockers, calcium channel blockers, ACE inhibitors and diuretics. The choice of medication is dependent upon several factors like the level of hypertension, presence of other diseases asthma, diabetes, and high cholesterol levels. The medicines have to be taken daily at a given time as advised by the doctor. Never stop the BP medicines without asking your doctor. It is very important to minimize the salt intake (two thirds of a teaspoon of table salt per day) and avoiding fast foods, pickles etc that contain high salt. Advantages of chirally pure drugs in hypertension: Pune-based Emcure Pharmaceuticals Ltd, a pioneer in chiral technology has developed S-Amlodipine (Asomex), SMetoprolol (Metpure-XL), SAtenolol (Atpure) which are the chirally pure medicines for hypertension and are available in India as well as several other countries. Asomex is not associated with the typical ankle swelling often seen with the ordinary amlodipine. These molecules as well as their combinations have shown good effectiveness and safety in Indian patients. Global multicentric clinical studies have been done showing the effectiveness of Asomex in thousands of hypertensives. Control the risk factors : Maintaining healthy lifestyle, avoiding of stress and minimizing salt intake (< 1500 mg of sodium /day) in the diet can minimize the risk of hypertension.