Download EFFECT OF SHENMAI INJECTION ON CARDIAC FUNCTION IN

Downloaded from http://heart.bmj.com/ on November 17, 2016 - Published by group.bmj.com
ABSTRACTS
GW23-e1725
EFFECT OF SHENMAI INJECTION ON CARDIAC
FUNCTION IN GERONTAL PATIENTS WITH CHRONIC
HEART FAILURE
doi:10.1136/heartjnl-2012-302920o.28
Tang Hao, Chen Zhibin, Liang Yanbing, Ma Zhongfu. Department of General Internal
Medcine of the First Affiliated Hospital of Sun Yan-sen University
Objectives To investigate the effect of Shenmai injection on the
therapeutic effect and cardiac function and brain natriuretic
peptide (BNP) in gerontal patient with chronic heart failure.
Methods 64 patients age more than 65 years with chronic heart
failure were randomly divided into two groups: the treatment
group (n=34) and control group (n=30). Patients in the control
group were given routine therapy including oxygen inhaling, cardiotonic, diuresis, blood vessels extension, correcting the fluid and
electrolyte imbalance, and the patients in the treatment group
were given Shenmai injection 100 ml every day underlying the
routine therapy. The course of treatment was 4 weeks. Observe
the NYHA class, left ventricular end diastolic diameters (LVEDD),
left ventricular ejection fraction (LVEF), cardiac output (CO),
stroke volume (SV) and serum BNP of the patients before and after
treatment.
Results Every index of cardiac function and BNP of patients in two
groups were significantly improved ( p<0.05). The total effective
ratios of the improvement about NYHA class in patients in treatment group (77.2%) is significantly higher than those in control
group (65.3%) ( p<0.05). And the LVEF (0.61±0.18), SV (60.30
±16.15) ml and serum BNP (300±25.6) ng/l of patients in treatment group after therapy were significantly different to the
patients in control group ( p<0.05), but there were no difference of
the LVEDD and CO of patients between two groups ( p>0.05).
Conclusions Shenmai injection association with routine treatment
can improve the therapeutic effect and cardiac funtion of the gerontal patients with chronic heart failure.
E242
Heart 2012;98(Suppl 2): E1–E319
Downloaded from http://heart.bmj.com/ on November 17, 2016 - Published by group.bmj.com
EFFECT OF SHENMAI INJECTION ON
CARDIAC FUNCTION IN GERONTAL
PATIENTS WITH CHRONIC HEART FAILURE
Tang Hao, Chen Zhibin, Liang Yanbing and Ma Zhongfu
Heart 2012 98: E242
doi: 10.1136/heartjnl-2012-302920o.28
Updated information and services can be found at:
http://heart.bmj.com/content/98/Suppl_2/E242.2
These include:
Email alerting
service
Topic
Collections
Receive free email alerts when new articles cite this article. Sign up in the
box at the top right corner of the online article.
Articles on similar topics can be found in the following collections
Drugs: cardiovascular system (8825)
Hypertension (3001)
Notes
To request permissions go to:
http://group.bmj.com/group/rights-licensing/permissions
To order reprints go to:
http://journals.bmj.com/cgi/reprintform
To subscribe to BMJ go to:
http://group.bmj.com/subscribe/