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Unit B1, B1.1 Mark scheme Keeping healthy 1. (i) the loop is sterilised accept to kill anything on the loop 1 or to kill any bacteria on it; do not credit to clean the loop (ii) if hot it would kill bacteria picked up (from culture); accept ‘microorganisms’ or ‘microbes’ accept entry of contaminated air but reject entry of air unqualified 1 (iii) to prevent entry (from the air) of unwanted bacteria or bacterial spores or fungal spores; accept so can’t breath on it; accept ‘microorganisms’ or ‘microbes’ 1 (iv) so that the (petri) dish is not opened (after bacteria are cultured) or to reduce evaporation or drying of the agar, accept ‘microorganisms’ or ‘microbes’ accept to prevent anything relevant getting in/out reject references to spillage 1 [4] 2. (a) being overweight do not accept fat unqualified; allow BMI over 25 1 (b) (i) rose 1 by 8% / from 16% to 24% / by 50% / rapidly then more slowly 1 any two reasonable suggestions 2 (ii) e.g. less active accept e.g.s like fewer jobs / more cars / less physically demanding employment OWTTE more food / take-aways / fast food (c) (i) high (blood) cholesterol do not accept combination of 2 labels ignore references to LDL and HDL 1 (ii) answer in range 8-17 inclusive 1 (iii) some deaths related to more than one factor 1 [8] 3. (a) any two from: • age • gender • mass • number in group • time 2 (b) any two from: • highest (mean) mass loss on Rosemary Conley or Rosemary Conley most effective • least (mean) mass loss in control group or mean 2 Page 1 of 3 Unit B1, B1.1 Mark scheme (c) (Atkins) costs least mass loss very similar to other diets or second highest mass loss or as effective as other diets 1 (d) any two from: • (exercise) increases metabolic rate / respiration ignore sweating • (exercise) needs / uses energy / calories allow burns fat / calories do not accept energy for respiration • (this) energy comes from food / fat • less food / energy/ calories converted to fat 2 [8] 4. (a) (b) antibodies allow antitoxins / memory cells do not allow antigens 1 immune ignore protection allow resistant 1 (i) (ii) fell 1 numerical qualification to zero / nothing / by 100% allow stopped in 1995 1 (no) 1 ignore circle % vaccination fell or when no vaccination but autism numbers did not fall / stayed high / increased or 1 ‘(yes) might support it if time lag between vaccination and autism symptoms’ / ‘time lag for diagnosis’ (1) 6 year time lag quantified (1) [6] 5. (a) (b) (i) diagram shows extensions of intact cell membrane around viruses 1 (ii) antibodies allow enzymes re (ii); allow interferon; ignore antitoxins / proteins 1 virus is transferred 1 (virus in) blood / body fluids – transfer (via needles) 1 [4] 6. (a) (b) (bacteria) produce toxins / poisons 1 (viruses) damage / kills cells or toxins released from cell 1 any two from: 2 • viruses live inside cells • viruses inaccessible to drug • drug would damage body cells / tissue Page 2 of 3 Unit B1, B1.1 Mark scheme (c) any four from: • overuse of antibiotics • bacteria mutate do not allow antibiotic causes mutation • antibiotics kill non-resistant strains or idea of selection • reduced competition • resistant bacteria reproduce 4 [8] 7 (a) antigens the same on non-virulent and virulent viruses; max 6 production of antibodies; by white blood cells / lymphocytes /B cells; destruction / killing of (vaccine) virus; cloning of B cells; immunological memory; rapid production of antibodies if exposed to “real” virus do not accept antibodies remain in blood or body (b) two marks for two of: max 2 possibility of introduction of virus from abroad; spread limited if most people immunised; economic benefits, e.g. reduced medical care bill; benefits to individuals e.g. less chance of paralysis / long-term effects; protection when going abroad; [8] Page 3 of 3