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UNIVERSITY STUDENT HEALTH SERVICES • Fact Sheet
CYTOLYTIC VAGINOSIS
WHAT IS IT?
Cytolytic vaginosis is a vaginal condition that involves an overgrowth of lactobacillus bacteria.
Lactobacilli are a normal part of the vaginal environment.
Cytolytic vaginosis is not an infection. It is also not a sexually transmitted illness.
WHAT CAUSES IT?
No one knows for sure. It appears to be a pH problem that causes a disruption in the natural
balance of bacteria found in the vagina. This leads to an overgrowth of lactobacillus, which
produces acids that cause vaginal irritation. A change in your vaginal pH may be provoked by,
but not limited to, the following:
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Treatment of vaginal discharge with antibiotics or antifungal medications
Residue from soap or vaginal cleansers
Sensitivity to chemicals or perfumes in personal care products
Sensitivity to latex or lubricants
The pH of your partner’s semen
WHAT ARE THE SYMPTOMS?
The symptoms of cytolytic vaginosis are often confused with those of a yeast infection or
bacterial vaginosis. Symptoms may be worse during the second half of your menstrual cycle.
Any of the following may be present:
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Itching and redness of the vagina or skin outside the vagina (the vulva).
Burning of the vulva which may be worse with urination. Symptoms may mimic the
burning associated with a urinary tract infection.
White or yellowish vaginal discharge.
Discomfort with intercourse or soreness following intercourse.
HOW IS IT DIAGNOSED?
Your medical provider will perform a pelvic exam and take a sample of your vaginal discharge to
examine under the microscope. The presence of characteristic cellular changes and excessive
lactobacilli help to confirm the diagnosis. Testing will also show a low vaginal pH.
WHAT IS THE TREATMENT?
Restoring the vaginal equilibrium will decrease lactobacilli to normal levels and provide
symptom relief.
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Baking soda treatments are used to increase vaginal pH:
o Baking soda soak: Dissolve 1-2 tablespoons of baking soda in a bath of 1-2 inches of
warm water. Soak twice a day for 15-20 minutes.
o Baking soda douche: Dissolve 1-2 tablespoons of baking soda in 4 cups of warm
water, or purchase an over-the-counter baking soda douche. Douche once daily for
7-14 days or twice weekly for 2 weeks.
o Baking soda paste: Make a watery paste with baking soda, and apply daily to the
skin outside the vagina to relieve any irritation.
WHAT IS THE TREATMENT? (continued)
• Stop tampon use (because menstrual flow increases vaginal pH).
• Avoid soap in the genital area. Wash with plain water. If you need soap, use a pHbalanced unscented bar soap, such as Olay or Dove. Avoid liquid soaps as they are
more concentrated.
• Avoid hygiene sprays and douches, as well as scented products like toilet paper, pads,
and tampons.
• Change out of wet clothing (eg. swimsuits, exercise clothing) as soon as possible.
• Avoid tight clothing that reduces air flow to the vulva.
• Wear cotton underwear. Sleeping without underwear may also help.
Consult your healthcare provider if your symptoms do not improve within 2-3 weeks of
treatment.
References: Health Update, The University of Virginia Student Health Service, Up To Date 2012
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Published by VCU Division of Student Affairs and Enrollment Services
University Student Health Services (804) 828-8828 - Monroe Park Campus clinic
(804) 828-9220 - MCV Campus clinic
Wellness Resource Center
(804) 828-9355 - 815 S. Cathedral Place
Reviewed 6/12