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4 MEDITERRANEAN CONFERENCE ON ONCOLOGY TH BREAST CANCER TREATMENT President: Danijel Dosen (Zagreb) ZAGREB, October 16-18, 2006 Board of Directors Colucci Giuseppe, Italy (President) Aranda Enrique, Spain (Vice President) Barchana Micha, Israel (Vice President) El Serafi Mostafa, Egypt (Vice President) Gebbia Vittorio, Italy (Secretary) Pizza Carmine, Italy (Treasurer) Scientific Commitee Mrsic-Krmpotic Zrinka, Croatia (President) Agostara Biagio, Italy Aranda Enrique, Spain Barchana Micha, Israel Bajetta Emilio, Italy Boussen Hamouda, Tunisia Counsellors Cariello Salvatore, Italy Cariello Salvatore, Italy Colucci Giuseppe, Italy Boussen Hamouda, Tunisia Comandone Alessandro, Italy Machover David, France Organizing Commitee Borsellino Nicolò, Italy Di Bisceglie Maurizio, Italy Dosen Danijel, Croatia Foggi Paolo, Italy Giotta Francesco, Italy Grah Josip, Croatia Grsic Kresimir, Croatia Oresic Tomislav, Croatia Roth Andrej, Croatia Savastano Clementina, Italy Separovic Robert, Croatia Solaric Mladen, Croatia Valerio Maria Rosaria, Italy Zorica Robert, Croatia Comandone Alessandro, Italy El Serafi Mostafa, Egypt Gebbia Nicola, Italy Gebbia Vittorio, Italy Knezevic Fabijan, Croatia Lopez Massimo, Italy Machover David, France Maiello Evaristo, Italy Manente Paolo, Italy 4 MEDITERRANEAN CONFERENCE ON ONCOLOGY TH BREAST CANCER REATMENT T President: Danijel Dosen (Zagreb) ZAGREB, October 16-18, 2006 Under the Auspices of Croatian Parliament Croatian Ministry of Health and Social Welfare Pizza Carmine, Italy Ministry of Science, Education and Sports Romito Sante, Italy Ministry of Health of the Italian Republic Schittulli Francesco, Italy Stanec Mladen, Croatia Strnad Marija, Croatia Samija Mirko, Croatia Tuveri Guido, Italy Venturini Marco, Italy Zagreb University School of Medicine Croatian Medical Association Zagreb City Government City Department of Health, Labour, Social Welfare and Veterans President, Vladimir Seks, LL.B. Minister, Neven Ljubicic, M.D., Ph. D. Minister, Dragan Primorac, M.D., Ph. D. Minister, Livia Turco, M.D., Ph. D. Dean, Professor Nada Cikes, M.D., Ph. D. President, Hrovje Sobat, M.D. Mayor of Zagreb, Milan Bandic Head, Zvonimir Sostar, M.D. Oncology Institute (NCI) of Bari Honorary Conference President Conference Organiser Professor Marko Turic, M.D., Ph.D. President, Croatian Parliament on Labour, Social Policy and Health Director, University Hospital for Tumors University Hospital for Tumors, Zagreb Introduction Dear colleagues, friends and guests, 08.30 After Bari, Alexandria and Tunis, Zagreb has been chosen as the venue for the 4th Mediterranean Conference on Oncology, and the University Hospital for Tumors has been entrusted with the honourable, yet responsible task of organising this important meeting to be hold in the Westin Hotel from 1618 October 2006 under the auspices of the Croatian Parliament, Ministry of Health and Social Welfare of the Republic of Croatia, Ministry of Science, Education and Sports of the Republic of Croatia, Zagreb University School of Medicine, Croatian Medical Association, Zagreb City Government and City Department of Health, Labour, Social Welfare and Veterans. The Mediterranean Oncology Society has unanimously decided that breast cancer is to be the topic of this year’s Conference, joining the awareness campaign for breast cancer for its increasing incidence among female population of the Mediterranean region and worldwide, too. This year’s event will feature 90 internationally recognised speakers and chairmen from 13 Mediterranean countries covering various aspects of their speciality and sharing with us all their vast experience in the field. Besides our time together spent in productive activities, there will also be time for casual socialising and time to enjoy of our Croatian capital. Danijel Dosen Opening Session Introduction (D. Dosen) I SESSION EPIDEMIOLOGY AND BIOLOGY OF BREAST CANCER Chairmen: M. Barchana, C. Pizza, S. Plestina 09.00 Epidemiological aspects in the Mediterranean area and in Croatia (M. Strnad) 09.30 Pharmacogenomics and breast cancer (A. Comandone) 09.50 Clinical application of gene profiling in breast cancer (P. Marchetti) 10.10 Prognostic significance of occult micrometastases (J. Pierga) 10.30 Discussion 11.00 Coffee break Looking forward to welcoming you in Zagreb. Conference President Monday, October 16 Monday, October 16 Monday, October 16 II SESSION III SESSION SCREENING AND DIAGNOSIS UPDATE IN LOCAL TREATMENT: SURGERY Chairmen: D. Cova, A. Gamoudi, B. Sarcevic 11.20 11.40 12.00 Breast cancer screening programmes: an overview (I. Abd El Bar) Chairmen: A. Bendib, A. Luini, N. Nola 14.30 Recent advances in breast imaging (Z. Herceg) Role of sentinel node biopsy and axillary dissection (M. Stanec) 14.50 Problems in pathological grading and staging of invasive breast cancer (F. Knezevic) New trends in surgical approach to breast cancer (D. Vrdoljak) 15.10 Breast re-construction after conservative surgery (W. Gareer) 15.30 Surgical treatment of non palpable lesions (D. Hershko) 15.50 Discussion 16.10 Coffee break 12.20 Nuclear imaging in breast cancer (P. Gerundini) 12.40 Clinical factors influencing treatment choice (G.B. Doglietto) 13.00 Discussion 13.20 Lunch Monday, October 16 Tuesday, October 17 IV SESSION V SESSION UPDATE IN LOCAL TREATMENT: RADIOTHERAPY ADJUVANT HORMONAL TREATMENT Chairmen: M. El Mistiri, Z. Rudolf, H. Sobat Chairmen: S. Celiku, G. Filippelli, D. Vrbanec 16.30 Postmastectomy radiation therapy (L. Beketic-Oreskovic) 09.00 Prognostic factors for adjuvant hormonotherapy (V. Lorusso) 16.50 Partial breast irradiation (A. Kuten) 09.20 Adjuvant endocrine therapies for premenopausal women (C. Rodriguez) 17.10 Role of radiotherapy in pN2 disease (L. Busutti) 09.40 Role and sequence of aromatase inhibitors in postmenopausal women (V. Adamo) 10.00 Ongoing international studies of hormonotherapy in pre and postmenopausal (M. De Laurentiis) 10.20 The regulation of ER-α in breast cancer (A. Giordano) 10.40 Discussion 11.00 Coffee break 17.30 18.00 Discussion OPENING CEREMONY Authorities welcome speeches 19.00 Cocktail 11.20 11.40 12.00 12.20 Tuesday, October 17 VI SESSION VII SESSION ADJUVANT CHEMOTHERAPY TREATMENT TREATMENT OF METASTATIC DISEASE (I) Chairmen: K. Bouzid, S. Cariello, N. Gebbia Chairmen: G. Foutzilas, E. Maiello Primary systemic therapy for operable breast cancer (R. Tomek) Tuesday, October 17 14.45 Optimizing sequence of endocrine treatment (S. Barni) 15.05 Combination chemotherapy: where are we? (M. Ghosn) 15.25 Adjuvant treatment in HER-2 positive breast cancer (Z. Mrsic-Krmpotic) Focus on docetaxel (V. Gebbia) 15.45 Liposomal doxorubicin (L. Manzione) Optimal chemotherapy regimen (L.G. Estevez) 16.05 Discussion 16.20 Coffee break Treatment in elderly patients (D. Vukas) 12.40 International studies (B. Pajk) 13.00 Discussion 13.35 Lunch Tuesday, October 17 VIII SESSION IX SESSION TREATMENT OF METASTATIC DISEASE (II) TREATMENT GUIDELINES Chairmen: G. Colucci, D. Machover, Z. Mrsic-Krmpotic 16.35 Wednesday, October 18 The role of antiangiogenetic therapy (G. Gasparini) 16.55 EGFR: monoclonal antibody (D. Vrbanec) 17.05 Tirosinakinasi inhibitors (N. Normanno) 17.25 New biomolecular drugs (S. Kurbel) 17.45 Discussion 18.05 Conclusion Chairmen: E. Aranda, M. Lopez, C. Papadimitriou 08.30 Europa donna (N. Kraljevic) 08.50 Treatment guidelines of breast cancer in University Hospital Tumors of Zagreb (Z. Mrsic-Krmpotic) 09.10 Treatment guidelines of breast cancer in European Institute of Oncology (IEO) of Milan (S. Cinieri) 09.30 Treatment guidelines of breast cancer in NCI of Cairo (M. El Serafi) 09.50 Treatment guidelines of breast cancer in the Institute G. Roussy of Paris (M. Spielmann) 10.10 Discussion 10.40 Coffee break Wednesday, October 18 X SESSION PALLIATIVE AND SUPPORTIVE CARE Chairmen: D. Dosen, V. Gebbia, G. Pacilio 11.00 Early postoperative rehabilitation of breast cancer patients (N. Kraljevic) 11.20 Correct use of haematological growth factors (S. Del Prete) 11.40 Implantable devices on medical oncology (H. Boussen) 12.00 Biophosphonates in the treatment of bone metastases (N. Dedic) 12.20 Oppioids and pain in malignant patients (F. Superina) 12.40 Discussion 13.00 Conclusions SPEAKERS AND CHAIRMEN Abd El Bar I. Adamo V. Aranda E. Barchana M. Barni S. Beketic-Oreskovic L. Bendib A. Boussen H. Bouzid K. Busutti L. Cariello S. Celiku S. Cinieri S. Colucci G. Comandone A. Cova D. De Laurentiis M. Dedic N. Del Prete S. Doglietto G.B. Dosen D. El Mistiri M. El-Serafi M. Estevez L.G. Filippelli G. Foutzilas G. Gamoudi A. Gareer W. Gasparini G. Gebbia N. Gebbia V. Gerundini P. Ghosn M. Giordano A. Egypt Italy Spain Israel Italy Croatia Algeria Tunisia Algeria Italy Italy Albania Italy Italy Italy Italy Italy Croatia Italy Italy Croatia Libya Egypt Spain Italy Greece Tunisia Egypt Italy Italy Italy Italy Lebanon Italy Herceg Z. Hershko D. Knezevic F. Kraljevic N. Kurbel S. Kuten A. Lopez M. Lorusso V. Luini A. Machover D. Maiello E. Manzione L. Marchetti P. Mrsic Krmpotic Z. Nola N. Normanno N. Pacilio G. Pajk B. Papadimitriou C. Pierga J.Y. Pizza C. Plestina S. Rodriguez C. Rudolf Z. Sarcevic B. Sobat H. Spielmann M. Stanec M. Strnad M. Superina F. Tomek R. Vrbanec D. Vrdoljak D. Vukas D. Croatia Israel Croatia Croatia Croatia Israel Italy Italy Italy France Italy Italy Italy Croatia Croatia Italy Italy Slovenia Greece France Italy Croatia Spain Slovenia Croatia Croatia France Croatia Croatia Croatia Croatia Croatia Croatia Croatia GENERAL INFORMATION CONFERENCE VENUE: THE WESTIN HOTEL Krsnjavoga, 1 • 10000 Zagreb (Croatia) • Phone: +385 14 892000 Italy: AGORÀ ORGANIZING SECRETARIAT via C.Rosalba, 41/A • 70124 Bari (Italy) Phone: +39 080 5093954 Fax +39 080 5093974 www.organizzazioneagora.it [email protected] Croatia: DEMARK Marticeva, 38/1 10000 Zagreb (Croatia) Phone: +385 01 4554166 Fax +385 01 4640524 1st MEDITERRANEAN CONFERENCE ON ONCOLOGY TREATMENT OF GASTROINTESTINAL CANCER Bari (Italy), 5-8 October 2003 2nd MEDITERRANEAN CONFERENCE ON ONCOLOGY MANAGEMENT OF LUNG CANCER AND MESOTHELIOMA Alexandria (Egypt), 8-10 December 2004 3rd MEDITERRANEAN CONFERENCE ON ONCOLOGY TREATMENT UPDATE OF UROLOGICAL AND GYNAECOLOGICAL CANCERS Tunisi (Tunisia), 24-26 November 2005 4th MEDITERRANEAN CONFERENCE ON ONCOLOGY BREAST CANCER TREATMENT Zagreb (Croatia), 16-18 October 2006 5th MEDITERRANEAN CONFERENCE ON ONCOLOGY See you in Bari 3-5 December 2007