Download Pancreatin Select

Pancreatin Select
™
The Moss Nutrition Professional Line
SUPPORT FOR ENHANCED DIGESTIVE COMFORT & FUNCTION
• Supports healthy gastric pH to initiate & promote digestion.*
• Betaine hydrochloride, pancreatin & pepsin help support
complete breakdown of food in stomach and duodenum.*
• Synergistic cofactors & acidulants boost efficacy.*
Other Ingredients: Cellulose (capsule), silica.
SUGGESTED USE: 1 CAPSULE WITH MEALS OR
AS DIRECTED BY YOUR HEALTHCARE PROFESSIONAL.
WARNING: IF TAKING MEDICATION, PREGNANT
OR NURSING, CONSULT A PHYSICIAN BEFORE
USING.
Pancreatin Select™ provides synergistic support for enhanced digestion
with meaningful levels of HCl plus gastric acid precursors, concentrated
pepsin and a high quality pancreatic enzyme blend. These ingredients
work together to help initiate the breakdown of proteins and bound
minerals in the stomach, and to promote healthy digestive comfort and
function in both gastric and intestinal environments.
Of the many factors that contribute to compromised digestive capacity,
insufficient stomach acid (hypochlorhydria, achlorhydria) and diminished
pancreatic enzyme production are two of the most common and widespread
(in most people, aging alone is a primary cause of both deficiencies). Both achlorhydria and pancreatic insufficiency are
associated not only with impaired digestion but with complications such as malnutrition and small intestinal bacterial
overgrowth (SIBO). Supplemental HCl, along with pepsin and pancreatic enzymes, can help boost the body’s natural
ability to break down and metabolize food in the critical early stages of digestion following a meal. The ingredients in
Pancreatin Select™ have been suggested to help support healthy digestion and nutrient absorption, to inhibit the growth
of pathogenic microbes and to improve digestive comfort overall.
BETAINE HCl and GLUTAMIC HCl are sources of hydrochloric acid, a key component of gastric juice. Naturally
secreted by parietal cells located in the gastric lining, HCl creates the acidic environment necessary to activate the
conversion of pepsinogen into pepsin, initiating protein digestion in the stomach. HCl is also necessary to cleave
minerals from their substrate and to kill foodborne microorganisms. Hypochlorhydria, typically marked by symptoms
of indigestion, gas and bloating, impairs protein digestion and leads to imbalances of gut microflora, pathogenic
microbial overgrowth and assorted micronutrient deficiencies—notably of calcium, iron, B6, B12 and folic acid.
(continued on reverse side)
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
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Tools for True HealthTM
800-851-5444
Pancreatin Select (continued from reverse side)
Hydrochloric acid is a powerful solvent (one of only six strong acids on Earth) and must be bonded to a carrier
molecule such as betaine, a methyl donor, or the amino acid glutamine for use in supplements. Betaine HCl is the
most widely used form of supplemental hydrochloric acid, whereas glutamic HCl has been reported to be gentler on
the stomach. Both work together in Pancreatin Select™ to offer synergistic support for a healthy gastric pH.
PANCREATIN 4X is a concentrated blend of pancreatic proteases, lipases and amylases intended to help facilitate the
breakdown of proteins, fats, and carbohydrates, respectively. Supplemental pancreatic enzymes help to offset reduced
enzymatic output by the exocrine pancreas, an organ which is strained by modern diets high in processed foods and
low in enzyme-rich raw and fermented foods. Diets high in sugars and starches similarly overstress the endocrine
pancreas, which must constantly produce hormones needed to balance blood glucose levels. Pancreatic insufficiency,
common in celiac disease and other digestive disorders, is a major cause of nutrient malabsorption. Taking pancreatic
enzymes augments the body’s natural output, promoting the thorough breakdown of nutritional components in
chyme entering the duodenum. For patients with pancreatic insufficiency, weak digestion or food sensitivities, supplementation with pancreatic enzymes can help enhance nutrient uptake as well as gastrointestinal comfort. The
pancreatin 4X concentrate used in Pancreatin Select™ is derived from a French porcine source.
PEPSIN is a proteolytic gastric enzyme activated in the low pH environment generated by the release of HCl. Pepsin
is responsible for the hydrolysis of proteins into peptides, increasing the amount of molecular surface area accessible
to pancreatic proteases and enabling complete digestion. Pepsin and HCl play a further role in gut-mediated immune
defense, protecting the body from pathogenic microbes that enter the body via oral ingestion.
AMMONIUM CHLORIDE is a classical acidulant and a source of chloride ions that helps support HCl activity.
VITAMIN B6 (pyridoxine) is a required cofactor in the production of hydrochloric acid and provides essential
support for protein and amino acid metabolism.
REFERENCES
1. Iwai W, et al. Gastric hypochlorhydria is associated with an exacerbation of dyspeptic symptoms in female patients. J Gastroenterol. 2013 Feb;48(2):214-21.
2. Sipponen P, Härkönen M. Hypochlorhydric stomach: a risk condition for calcium malabsorption and osteoporosis? Scand J Gastroenterol. 2010;45(2):133-8.
3. Layer P, Keller J. Pancreatic enzymes: Secretion and luminal nutrient digestion in health and disease. J Clin Gastroenterol. 1999 Jan;28(1):3-10.
4. Bures J, et al. Small intestinal bacterial overgrowth syndrome. World J Gastroenterol. 2010 Jun 28;16(24):2978-90.
5. Thorat V, et al. Randomised clinical trial: the efficacy and safety of pancreatin enteric-coated minimicrospheres (Creon 40000 MMS)
in patients with pancreatic exocrine insufficiency due to chronic pancreatitis--a double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2012 Sep;36(5):426-36.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
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Hadley, MA 01035
800-851-5444