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Syllabus Academic Year: Group of subjects: basic / professional Module title1): Biochemistry – module I Polish Translation3): Biochemia – moduł I Faculty4): Faculty of Veterinary Medicine Person in charge of the module5): prof. dr hab. Bogdan Dębski Teachers responsible for laboratory classes, workshops and seminars6): prof. dr hab. Bogdan Dębski, dr hab. Tomasz Kurył, dr Małgorzata Gajewska, dr Alicja Majewska Unit responsible for the module7): Biochemistry Division of the Department of Physiological Sciences, Faculty of Veterinary Medicine Faculty in charge8): Faculty of Veterinary Medicine Module status9): a) mandatory / elective Teaching cycle10): Objectives of the module12): Teaching forms and number of hours13): Teaching methods14): Detailed module description15): Formal prerequisites16): Initial requirements17): Semester: winter / summer Catalogue number: ECTS 2) b) stage JM Module year 1 language11): 4 c) intramural English The aim of the module I of Biochemistry Course is to teach students about the structure and main functions of biochemical compounds (vitamins, carbohydrates, lipids, amino acids, proteins, nucleic acids, porphyrins) and necessary macro-, and microelements. During the practical part of the course students are performing qualitative and quantitative analyses to detect the presence and properties of the studied biochemical compounds. After the first module of Biochemistry Course students should know the structure and characteristics of compounds from all studied biochemical groups, and detect these compounds in an unknown biological sample. Module I of Biochemistry prepares the students to the second level of Biochemistry course (module II), during which they are taught the main metabolic pathways in the organism. Additionally it prepares the students to participation in the courses of: animal physiology, pharmacology, toxicology. a) Lectures (15h) b) Laboratory practicals (45h) c) Simple biochemical experiments with the use of biochemical analyses, PowerPoint presentations during lectures, consultations. Lecture topics cover: homeostasis, water In living organisms, water content in different types of tissues, pH, dynamic equilibrium; macro- , microelements and their main functions in the organism, elements antagonism and synergism, transport and binding proteins, role of metals in the organism diseases caused by their deficiency; exogenous substances: vitamins soluble in water and vitamins soluble in lipids; types, structure and properties of amino acids; organisation of proteins; allostery; role and classification of enzymes; structure and metabolism of carbohydrates, lipids, steroids, nucleotides and nucleic acids; DNA and RNA molecular biology; structure and functions of porphyrins, role of the degradation products of heme. During the practical part students: learn how to establish mineral composition of living organisms; detect vitamins; evaluate structure and properties of amino acids and proteins; evaluate activity of enzymes; test structure and properties of carbohydrates; properties of lipids, cholesterol; detect nucleotide components; identify nucleic acids; establish structure and properties of porphyrins. Lectures supplement and extend the information provided during the practical part of the course. Students should finish the Chemistry course with a positive grade before starting the module I of Biochemistry course. Participating students should have a good knowledge of chemical compounds and processes, and be familiar with basic methods used in chemical analyses (quantitative and qualitative). 1 Learning outcomes18): After finishing the module I of Biochemistry course student should be able to: 01 – describe the structure of biochemical compounds from the main groups (carbohydrates, amino acids, proteins, lipids, nucleic acids, porphyrins, vitamins) 02 – define properties of biochemical compounds on the basis of their characteristic reactions 03 – explain the role of the biochemical compounds from the main groups in the organism 04 – understand and know the role of macro-and microelements in the proper functioning of animal and human organism 05 – define the signs and consequences of the deficiencies of vitamins and macro-, and microelements in the organism Assessment methods19): Effects: 01-05 – verification tests during laboratory practicals; Effects: 06-09 – assessment of the effects and interpretation of performed experiments; verification tests during laboratory practicals Formal documentation of the learning outcome20): Elements impelling final grade21): After finishing the module I of Biochemistry course students should have the ability to: 06 – identify the biochemical compounds on the basis of their characteristic reactions 07 – determine properties of biochemical compounds on the basis of their characteristic reactions 08 – perform qualitative and quantitative analysis of investigated compounds 09 – interpret the results of biochemical analyses. Grade cards of students, test papers signed by students, exam protocol and exam papers signed by students, grade in the eHMS system 51-100% of the total number of points scored on each of the 3 verifications tests gives a positive grade from the module I of Biochemistry course. DETAILED SYSTEM OF EVALUATION: Participation in practicals of the biochemistry course is obligatory. Students are allowed to miss max. 3 practicals (without giving justification of the absence). Theoretical preparation of students to current practical will be verified by small tests (7 during semester). Students are able to obtain max. 1 point for each small test, which gives a total of 7 points added to the sum of points obtained during the practical part of Biochemistry course – module I. Detailed knowledge of topics presented during practicals and corresponding lectures will be verified during main tests – 3 during semester . During each verification test student is able to obtain 21 points max. (7 open questions, each for 3 points). Each verification test is passed when a student obtains at least 52% of the total amount points (11 points min.). Each main test can be repeated once during the semester, allowing students to correct the grade. Students are obliged to obtain a positive grade from EACH of the 3 verification tests to receive a positive grade from the biochemistry course – module I. The total number of points that a student can obtain during the Biochemistry course – module I is 70: 21 points (verification test) * 3 = 63 points max. 1 point (small test during practicals) * 7 = 7 points max. ∑70 points max. Teaching base22): Point scale and corresponding grade scale for the FINAL GRADE AFTER BIOCHEMISTRY COURSE – MODULE I: No. of points: Grade: 0.0 – 35.0 2.0 (failed) 36.0 – 42.0 3.0 (sufficient) 43.0 – 49.0 3.0 (sufficient +) 50.0 – 56.0 4.0 (good) 57.0– 62.0 4.5 (very good) 5.0 (excellent) 63.0 – 70.0 Lecture Rooms of the Faculty of Veterinary Medicine, Laboratories of the Biochemistry Division at Department of Animal Physiology, B Faculty of Veterinary Medicine Obligatory and supportive materials23): 1. 2. Lippincott's Illustrated Reviews Biochemistry Fourth edition by Pamela C. Champe, Richard A. Harvey, Denise R. Ferrier ; Lippincott Williams & Wilkins 2008 Clinical Biochemistry of Domestic Animals, fifth edition, by J.Jerry Kaneko, John W. Harvey, Michael L.Bruss; Academic Press 1997 Annotations24): 2 Quantitative summary of the module25): Estimated number of work hours per student (contact and self-study) essential to achieve presumed learning outcomes of the module18) - base for quantifying ECTS2: 100 h Total ECTS points, accumulated by students during contact learning: 3 ECTS Total ECTS points, accumulated by student during practical classes (laboratories, projects, seminars, etc.): 2.0 ECTS Learning outcomes of the module relative to the learning outcomes of the subject26): Outcome No / symbol Learning outcomes: Relative to the learning outcomes of the subject: 01 describing the structure of biochemical compounds from the main groups (carbohydrates, amino acids, proteins, lipids, nucleic acids, porphyrins, vitamins) WW_NP4 02 defining properties of biochemical compounds on the basis of their characteristic reactions WW_NP4 03 explaining the role of the biochemical compounds from the main groups in the organism WW_NP4 04 05 understanding and knowing the role of macro-and microelements in the proper functioning of animal and human organism defining the signs and consequences of the deficiencies of vitamins and macro-, and microelements in the organism WW_NP4 WW_NP4 06 identifying the biochemical compounds on the basis of their characteristic reactions U_PUZ6 07 determining properties of biochemical compounds on the basis of their characteristic reactions U_PUZ6 3