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Drug Therapy Protocols: Glucose 10% Disclaimer and copyright ©2016 Queensland Government All rights reserved. Without limiting the reservation of copyright, no person shall reproduce, store in a retrieval system or transmit in any form, or by any means, part or the whole of the Queensland Ambulance Service (‘QAS’) Clinical practice manual (‘CPM’) without the priorwritten permission of the Commissioner. The QAS accepts no responsibility for any modification, redistribution or use of the CPM or any part thereof. The CPM is expressly intended for use by QAS paramedics whenperforming duties and delivering ambulance services for, and on behalf of, the QAS. Under no circumstances will the QAS, its employees or agents, be liable for any loss, injury, claim, liability or damages of any kind resulting from the unauthorised use of, or reliance upon the CPM or its contents. While effort has been made to contact all copyright owners this has not always been possible. The QAS would welcome notification from any copyright holder who has been omitted or incorrectly acknowledged. All feedback and suggestions are welcome, please forward to: [email protected] Date October, 2015 Purpose Scope Author To ensure a consistent procedural approach to Glucose 10% administration. Applies to all QAS clinical staff. Clinical Quality & Patient Safety Unit, QAS Review date October, 2017 URL https://ambulance.qld.gov.au/clinical.html This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/. Glucose 10% October, 2015 Drug class Side effects Hyperglycaemic UNCONTROLLED WHEN PRINTED Pharmacology • Nil Glucose is a sugar that is the principal energy source for body cells, especially the brain.[1] Metabolism Presentation Broken down in most tissues and distributed throughout total body water.[2] • Viaflex® plastic container, 250 mL glucose 10% (25 g) UNCONTROLLED WHEN PRINTED Indications • Symptomatic hypoglycaemia (with the inability to self-administer oral glucose) Onset Duration Half-life Rapid Not applicable Not applicable UNCONTROLLED WHEN PRINTED Contraindications Schedule • Unscheduled. Intravenous infusion (IV INF ) CCP Routes of administration ACP2 • Nil • Hyperglycaemia Intraosseous infusion (IO INF ) CCP UNCONTROLLED WHEN PRINTED Precautions Figure 4.16 QUEENSLAND AMBULANCE SERVICE 761 Glucose 10% October, 2015 Adult dosages Special notes UNCONTROLLED WHEN PRINTED Symptomatic hypoglycaemia CCP ACP2 (with the inability to self administer oral glucose) IV INF 15 g (150 mL) Repeated at 100 mL (10 g) boluses every 5 minutes until BGL > 4.0 mmol/L. • Glucose 10% is the preferred treatment for hypoglycaemia for patients unable to take oral glucose. This is due to its rapid onset and ability to quickly restore blood glucose concentration to normal values.[2] CCP UNCONTROLLED WHEN PRINTED IO INF 15 g (150 mL) Repeated at 100 mL (10 g) boluses every 5 minutes until BGL > 4.0 mmol/L. Paediatric dosages UNCONTROLLED WHEN PRINTED Symptomatic hypoglycaemia CCP ACP2 (with the inability to self administer oral glucose) IV INF 0.25 g/kg (2.5 mL/kg) Repeated at 1 mL/kg (0.1 g/kg) boluses every 5 minutes until BGL > 4.0 mmol/L. IO INF 0.25 g/kg (2.5 mL/kg) Repeated at 1 mL/kg (0.1 g/kg) boluses every 5 minutes until BGL > 4.0 mmol/L. CCP UNCONTROLLED WHEN PRINTED QUEENSLAND AMBULANCE SERVICE 762