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Diabetes & selected medications Medical-surgical Nursing Chapter 64-Iggy-Pg 1300 NUR 152 Mesa Community College Learning Outcomes  Describe how insulin works in the body and the effects of too little or no insulin production in the body  Differentiate between type 1 and type 2 diabetes mellitus  Explain the complications that can result from diabetes mellitus  Use the nursing process to create nursing care plans for diabetic patients  Administer the prototype drug metformin safely and effectively  Differentiate between rapid, fast, intermediate, and long acting insulin  Review the appropriate steps when mixing insulin  Understand the nursing implications when administering insulin  Review the proper techniques in blood glucose monitoring  Identify diabetic patients in a state of hyperglycemia or hypoglycemia, and those at risk for these conditions  Describe diabetic foot care  Describe managing complications from diabetes Insulin in the body (Pg 1302)  Insulin is needed to move glucose into body tissues  Absence of insulin makes the body break down fat and protein for energy  Absence of insulin ↑ the levels of other hormones in order to attempt to make glucose from other sources  Resulting in hyperglycemia (high blood glucose levels)  Polyuria  Polydipsia  Polyphagia Type I Diabetes (DM I) (Pg 1306)  Autoimmune disorder where the beta cells are destroyed in the pancreas leading to no insulin production  Genetically handed down (tissue type HLA-DR or HLA-DQ)  Antibodies exist to work against beta cells and insulin  Usually younger onset Type II Diabetes (DM II) (Pg 1306) *See pg 761 in Iggy as well  Insulin resistance and decreased insulin production  Most are obese  Hereditary plays a major role  Gene defects may also play a role  *Metabolic Syndrome (any 3)  Abdominal obesity  Hyperglycemia  Hypertension  Hyperlipidemia Chronic Complications of Diabetes (Pg 1303-1306)  Macrovascular Complications  Cardiovascular Disease  Cerebrovascular Disease  Microvascular  Eye Complications & Vision  Diabetic Neuropathy  Diabetic Nephropathy  Male ED  Cognitive Dysfunction Nursing Process & Diabetes  Assessment  Health History  Laboratory Results  Screening  Ongoing  Urine Assessment Tests Nursing Diagnoses  Risk for injury r/t hyperglycemia  Potential for impaired wound healing r/t endocrine and vascular effects of diabetes  Risk for injury r/t diabetic neuropathy  Acute pain r/t diabetic neuropathy  Chronic  Risk pain r/t diabetic neuropathy for injury r/t diabetic retinopathyreduced vision Outcomes (Goals)  Performs treatment regimen as prescribed  Follows recommended diet  Monitors blood glucose using correct testing procedure  Manages symptoms of hyper/hypoglycemia  Seeks health care if blood glucose levels go outside of recommended parameters  Meets recommended activity levels  Uses medications as prescribed  Maintains optimum weight Oral Therapy  Drug (Pg 1310-1312 Chart 64-2) Therapy: DM II (Anti-diabetic, oral, Biguanide)  metformin (Glucophage)  Recommended  Inhibits as initial therapy in type 2 diabetes mellitus hepatic glucose production  Increases sensitivity of tissue to insulin  Not given to people with kidney disease or elevated creatinine levels  Look up in SkyScape as well! Insulin- Where does it come from and why do we need it?  Pancreas - Beta cells in islets of Langerhans produce:  Insulin - needed for metabolism of carbs, fats, proteins (helps move glucose into cells)  Glucagon - stimulates conversion of glycogen to glucose in the liver  Normal adult blood sugar - 70 to 110 mg/dL Nursing Implications  Insulin  Check  Roll blood glucose level before giving insulin vials between hands instead of shaking them to mix suspensions  Ensure  Only correct storage of insulin vials use insulin syringes, calibrated in units, to measure and give insulin  Ensure correct timing of insulin dose with meals  Insulin order and dosages are second-checked with another nurse Copyright © 2014 by Mosby, an imprint of Elsevier Inc. 12 Insulin (Pg 1313-1315) Rapid Acting  Novolog (aspart)/Humalog (lispro)  Rapid Acting-Clear  Given right before a meal  Onset: 15-30 minutes  Peak:  1-3 ½  hrs (aspart) to 1&1/2 hours (lispro) Duration:  3-5 5 hours (aspart) hours (lispro) Short Acting  Regular (Humulin R/Novolin R)  Short Acting-Clear  Given ½ to 1 hour before a meal  Onset:  Peak: 30 minutes 2 to 5 hours  Duration: up to 7-8 hours Insulin (continued) Intermediate Acting  Humulin N/Novolin N (isophane)-NPH (Neutral Protamine Hagedorn)  Intermediate Acting  Onset:  Peak: 1&1/2 – 4 hours 4-14 hours  Duration:  Cloudy 10-24 hours Insulin (continued) Long Acting  Lantus (glargine)  Levemir (determir)  Long Acting  Long Acting  Onset:  Peak: 2 – 4 hrs None  Duration:  Never 24 hrs mixed with another insulin!  Usually  Onset:  Peak: given twice a day 1 hours 6-8 hours  Duration  Never ~ 5 to 24 hours mixed with another insulin! Mixing Insulin  ATI Skills Diabetes Management  Step by Step Viewing  Mixing  Soft insulin Fundies Sliding-Scale Insulin Dosing Subcutaneous short-acting or regular insulin doses adjusted according to blood glucose test results  Typically used in hospitalized diabetic patients or those on total parenteral nutrition (TPN) or enteral tube feedings  Subcutaneous insulin is ordered in an amount that increases as the blood glucose increases  Disadvantage: delays insulin administration until hyperglycemia occurs; results in large swings in glucose control  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. 19 Sliding scale example  Regular Insulin sliding scale subcutaneous with meals and at bedtime  151-200= 2 units  201-250= 4 units  251-300= 6 units  301-350= 8 units  351-400=10 units  >400=Call prescriber Patient Education  Blood Glucose Monitoring  Target goals - Daily sugars  HgbA1C (pg 1308-9)  Technique  Rotating sites  Timing  Recording  Recognizing and reporting results & problems Glucose-Elevating Drugs  Oral forms of concentrated glucose  Buccal tablets, semisolid gel  50% dextrose in water (D50W)  Glucagon Copyright © 2014 by Mosby, an imprint of Elsevier Inc. 24 Interventions (cont): (1330-1332) Nutrition Therapy Exercise Therapy  Nutrition Principles  Regular Exercise  Carbohydrate intake  Diabetic Adjustments  Dietary fat & cholesterol  Safety Assessment  Protein  Special considerations Preventing Injury from Peripheral Neuropathy  Foot Care (Chart 64-6) Preventing foot injuries  Keeping blood sugars in check  Foot inspection (Chart 64-5)  Good fitting shoes  Proper nail trimming    Do not go barefoot! See your physician immediately for any break in skin Managing complications Managing Neuropathic Pain Reduced Vision  Anticonvulsants  Blood Glucose control  Antidepressants  Regular eye exams  Creams  Environmental management  Maintain Stable Glucose  Large print  Bed cradle  Low vision aids  Good lighting  Audio tools  Syringe magnifiers