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Wet, cold and injured Mikael S Mikaelsson, ED registrar Christchurch We are the sum of our past Overview • • • • • • • A few general words Hypothermia Near Drowning Avalanche survival Questions 5 minute breather Chris Hill A warning • Very little randomised research • Mostly anecdotal, case series and animal research • “Truth” is derived from consensus, the application of basic principles and maybe a little common sense Hypothermia • Text book definition: – a state in which the body's mechanism for temperature regulation is overwhelmed in the face of a cold stressor • A shorter definition: – when core temperature is lower then 35 C History • Immobility • Age – Young and Old at risk • Increased heat loss; – Cold, Wet, Wind • Fatigue and starved • Medical co morbidities • Drug effects Mechanisms of Heat Loss • • • • • Radiation Conduction Convection Respiration Evaporation Prehospital a not so perfect world • First keep your self safe • Avoid further harm/stabilise • Approximate and adapt – and as for the rest just do the best you know how You can’t always get what you want…. • Darkness • Poor weather • Lack of equipment and resources • Minimal back up Prehospital • Goals in hypothermia – To prevent further heat loss, to start core rewarming and to avoid precipitating malignant cardiac rhythms Prehospital • Specifically – Gentle handling – Move to a warm/protected environment – Warm and dry clothing – If possible horizontal extraction and transfer, especially from cold water – Start active core rewarming – Be prepared for extended CPR if significant hypothermia Not just an outdoor disease • Patients presenting to ED from home are commonly hypothermic. • It’s generally a poor prognostic sign as often secondary to extended immobility and underlying disease Cold, Colder, Coldest • Hypothermia is subclassified into (core temperature): – Mild • 32-35 C – Moderate • 28-32 C – Severe • below 28 C Not every one is made the same • We can give thanks for that Adriana Iliescu Mild hypothermia • Patients are generally are stable haemodynamically and able to compensate for the symptoms • 34 C - 35 C – most people shiver vigorously • Below 34 C, – altered judgment, amnesia, and dysarthria. Respiratory rate may increase. • At approximately 33 C – ataxia and apathy may be seen • The following may also be observed: – hyperventilation, tachypnea, tachycardia, and cold diuresis as renal concentrating ability is compromised Moderate • The body starts to shut down and compensatory mechanisms fail • Most patients with temperatures of 32 C or lower present in stupor. • At 30 C, patients develop a higher risk for arrhythmias. – The pulse slows and Atrial as well as Ventricular rythms are seen. A J wave starts to be seen. • Between 28 C and 30 C, pupils can become markedly dilated and minimally responsive to light. • Some patients have paradoxical undressing Severe • < 28 C, the body becomes very susceptible to VF • <27 º C, 83% of patients are comatose. • Can appear dead • Pulmonary oedema, depressed cardiac output, oliguria, coma, hypotension, rigidity, apnoea, pulselessness, areflexia, unresponsiveness, fixed pupils, and decreased or absent activity on EEG At Hospital • Assess ABC • Measure core temperature • Monitor • Assess cardiac rhythm • Assess patient for other problems and injuries • Don’t forget the basics Rhythm abnormalities • Common in moderate and severe • Bradycardia • Slowing of conduction • J (Osborne) waves • Atrial arrhythmias • Ventricular arrhythmias J waves (Osborne) Best rewarming strategy? • Disputed, but always start with the basics of a warm dry shelter and clothing. • For mildly hypothermic patients, pick any gentle warming method that is practical • For the profoundly hypothermic – If stable warm fluids, warm air and warming blankets – If unstable or in resuscitation, invasive warming Invasive rewarming • • • • Peritoneal lavage Bladder lavage Thoracic lavage Cardiopulmonary bypass Cardiac Arrest • Optimal ratio of compression vs ventilation unknown • Defibrillation and medications have minimal to no effect on a cold heart • Give warm fluids to minimise rewarming shock and to increase drug effect • Bretylium may work on arrhythmia • Warm patient to 33 C • Have faith Bretylium Tosylate • Antidysrhythmic (Class III) • Can be used both prophylactically and to treat VT and VF in hypothermia • Initial dose 5mg/kg, subsequent doses 10mg/kg • Bretylium has been discontinued by all manufacturers Mortality • Survival in mild hypothermia is excellent • Mortality in moderate hypothermia 21% • Mortality in severe hypothermia 40% • Very dependant on comorbidities The luckiest • World record holders: – 9º C - Lowest reported survivor from therapeutic exposure. – 14.4 C – Lowest reported infant survival from accidental exposure. – 13.7º C – Lowest reported adult survival from accidental exposure. Dr Anna Bågenholm No one is dead, unless warm and dead or….. • K >10? • Core temp under 12 C? • Obvious fatal injury • Submersion >1hr? • A chest that is so frozen that CPR is impossible • Rescuers at risk Paradoxical undress and burrowing • 69 cases of death due to lethal hypothermia • 25% showed signs of undress of partial or complete undress • All of those had moved into an smaller space Terminal burrowing behaviour M. A. Rothschild, Arch Kriminol. 1991 JanFeb;187(2):47-56 Submersion injury Drowning • NZ death toll 114 per year on average • 60% recreational • NZ has one of the highest drowning rates of any developed nation • It is consistently the third highest cause of unintentional death, surpassed only by road vehicle crashes and accidental falls Near Drowning • Defined as survival for 24hours after submersion • For every death 4 hospitalizations and 14 ED visits are due to submersion injuries Some arbitrary distinctions • • • • Warm >20 Cold <20 Very cold <5 Possibly some small benefit of very cold water for young children as anecdotal stories of paediatric survival with extended submersion • Adults in cold water submersion, no increase in survival Not Hollywood • Most people are found submerged for an unobserved period of time and often unclear cause Prognosis • The prognosis is directly related to the duration and magnitude of hypoxia. • The most significant impact on morbidity and mortality occurs before the patient arrives at the hospital. • Poor survival is associated with the need for continued cardiopulmonary resuscitation efforts on arrival to the hospital. – Of these patients, 35-60% die in the ED. – Of the survivors, 60-100% have long-term neurologic sequelae. The good news • If your patient is awake with minimal symptoms from lungs on arrival to hospital then they generally do very well Orlowski score • Orlowski score has been found to identify the likelihood of neurologically intact survival. • 2 items or less a 90% • 3 items or more have only a 5% • Age 3 years or older • Submersion time of more than 5 minutes • No resuscitative efforts for more than 10 minutes after rescue • Comatose on admission to the emergency department • Arterial pH of less than 7.10 “benefits” of very cold water • The neuroprotective effects of cold-water drowning are poorly understood. – Hypothermia profoundly decreases the cerebral metabolic rate. – Neuroprotective effects seem to occur only if the hypothermia occurs at the time of submersion and only if very rapid cooling occurs in water with a temperature of less than 5 C. Wim Hof, world record holder for longest swim under ice “Cold” water • Thermal conduction of water is 25-30 times that of air. • Physical exertion increases heat loss up to 35-50% • A significant risk of hypothermia usually develops in water temperatures less than 25 C • During immersion in very cold water, – hypothermic in approximately 30 minutes – life-threatening in approximately 60 minutes Prehospital resuscitation • Standard advanced life support • But remember – Safety first, don’t be another statistic – Trauma, especially in diving accidents – First focus is ventilation – Start ventilation in the water if necessary – Hi flow O2 if any pulmonary concerns Just a reminder • Treat cold water submersions gently • Hypothermia is common • Arrhythmias at rescue well known and have a poor prognosis In hospital • • • • CNS 2 to asphyxia Trauma from event Hypothermia ARDS – even small aspirations problematic • Observe for pulmonary complications A few words… • Salt vs fresh water aspiration is an academic distinction • No benefit in prophylactic antibiotics – (Unless they drowned in a sewer pond) • Never forget the Cspine Avalanches Simple in theory • Get patients free fast • Treat for – Asphyxia – Hypothermia – Multi trauma Dismal survival curve Quick as they can.. • Discounting initial trauma deaths, survival is then dependant on – Being found quickly – Being dug out efficiently – Initial resuscitation • But best of all don’t get caught in one Just belabouring the point • The impact of avalanche transceivers on mortality from avalanche accidents – High Alt Med Biol. 2005 Spring;6(1):72-7 • 278 totally buried victims • reduction in mortality from 68.0% to 53.8% (p=0.011) • reduction in median burial time from 102 to 20 min (p < 0.001) Not all made the same • 23:00,11th of March, 1984 a small fishing vessel capsized 6km off Iceland • The air temperature was -2 C, and the sea a frigid 5-6 C • Guðlaugur survived 6 hours swimming and the 3 hour climb/walk to safety Guðlaugur_Friðþórsson Determination! Questions? Be Safe