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Goldmann Applanation Tonometry Ted Barnett E.M.B. Sept. 2000 Introduction • Applanation tonometry: measures IOP by providing force which flattens the cornea. • Variable force applanation tonometers (Goldmann, Perkins, Draeger, MacKayMarg, and Tono-Pen and Pneumatonometer): area of the cornea being applanated held constant, variable for applied. E.M.B. Sept. 2000 Principles • based on Imbert-Fick law: pressure within a sphere (P) is roughly equal to the external force (f) needed to flatten a portion of the sphere divided by the area (A) of trhe sphere which is flattened: P = f / A • applies to surfaces which are perfectly spherical, dry, flexible, elastic and infinitely thin E.M.B. Sept. 2000 Principles (cont.) • include force of cornea which pushes applanating surface away from eye (N), subtract surface tension of tear film toward the eye (M) • since cornea has thickness, consider only flattening of inner corneal area (A1) • P = f / A1 + M - N • when A1 = 7.35, M and N cancel out so: • P = f / 7.35 mm2 E.M.B. Sept. 2000 Principles (cont.) • this internal area achieved when diameter of external area of corneal applanation is 3.06mm • at this external diameter, grams of force applied multiplied by 10 is directly converted to mmHg • measured pressure is 3% greater than IOP before applanation (not corrected) • minimal displacement (0.5ul) of fluid or increase in IOP with applanation, thus unaffected by ocular rigidity E.M.B. Sept. 2000 E.M.B. Sept. 2000 Technique of measurement • plastic biprism which contacts cornea creates two semicircles • edge of corneal contact is visible after placing fluorescein into tear film & viewing with cobalt blue light • manually rotate the dial calibrated in grams, force is adjusted by changing the length of a spring within the device. • inner margins of semicircles touch when 3.06 mm of cornea is applanated. E.M.B. Sept. 2000 E.M.B. Sept. 2000 Instructions to patient • press head firmly against chin and forehead rest. • look straight ahead and fixate on a target (e.g. examiners opposite ear) • breathe normally, do not hold your breath • blink immediately prior to measurement to moisten cornea. E.M.B. Sept. 2000 Measurement (cont.) • position patient’s head with forehead rest well above eyebrows, allowing raising of eyebrows. • anesthetic & fluorescein (0.25%) ,separately, or as mixture (preserved) placed in inferior cul-de-sac. • with maximal illumination of biprism the lamp is moved toward the eye until the tip of biprism contacts the apex of the cornea • stop moving forward when limbus shines with light, best observed with naked eye E.M.B. Sept. 2000 Measurement (cont.) • After contact, semicircles visible through left (or right) ocular. Center in field of view. • Adjust vertically until semicircles equal in size. • Tension dial adjusted so that inner edge of upper and lower semicircles are aligned. • Multiply dial reading (grams of force) by 10 to obtain IOP (mmHg) • Read at median over which arcs glide to control for excursions due to ocular pulsations. E.M.B. Sept. 2000 E.M.B. Sept. 2000 Measurement (cont.) • If slit-lamp moved too far toward patient the pressure arm will push against a spring which will press against the eye with a low inoffensive force. • Mires (flattened area) too large, moving dial doen’t alter appearance. • Solution: Draw back until regular pulsation noted and appearance of mires normalizes. E.M.B. Sept. 2000 Measurement (cont.) • Blue central area represents applanated cornea, green semicircles are fluorescein-stained tears, inner border of ring is demarcation between flattened and non-flattened cornea. • Without staining of tears, bright reflection from air-cornea interface is seen; leads to underestimation of IOP. • Mires should be approximately 10% of circle width. E.M.B. Sept. 2000 Errors in Measurement • The fluorescein ring is too wide or too narrow: • Too wide: occurs if prism not dried after cleaning or lids touch prism. Overestimates IOP. Solution: dry prism • Too narrow: inadequte fluorescein concentration may cause hypofluorescence. Underestimates IOP. Solution: patient blinks or additional fluorescein added. E.M.B. Sept. 2000 Errors (cont.) • thin corneas produces underestimate • thick cornea d/t increased collagen gives overestimate, if d/t edema gives underestimate. • inadequate vertical alignment of semicircles leads to overstimate of IOP. • distortion d/t irregular cornea influences accuracy, less useful with corneal scarring. E.M.B. Sept. 2000 Errors (cont.) • squeezing of eyelids, breath holding or other Valsalva maneuvers, pressure on globe, excessive EOM force applied to restricted globe, vertical gaze, tight collars, retreating patient, inaccurately calibrated tonometer. • repeated tonometry may induce decline in estimated IOP. E.M.B. Sept. 2000 Error d/t corneal curvature • increase of 1 mmHg for every 3D increase in corneal power. • more fluid displaced under steep cornea, increases contribution of ocular rigidity in overestimating IOP. • the steeper the cornea, the more cornea must be indented to produce standard area of contact. • >3D astigmatism produces elliptical rather than circular area E.M.B. Sept. 2000 Correction for astigmatism • With semicircles displaced horizontally, IOP underestimated by 1 mmHg for every 4D of WTR astigmatism, vice versa for ATR astigmatism. • To minimize, prisms should be rotated so that axis of least corneal curvature is opposite red line on prism holder (i.e. align negative cylinder axis). • Can average reading with vertical and horizontal alignment of prism. E.M.B. Sept. 2000 Sterilization • CDC recommendation (HIV, HSV, and adenovirus): wipe tip clean and disinfect tip only with bleach (1:10 dilution x 5”, changed once daily). • Alternative is 3% H2O2, changed at least twice daily (affects tip less than bleach or ETOH). • Alternative #2: wiping tip with 70% ETOH E.M.B. Sept. 2000 Reliability • Goldmann applanation is standard against which others measured. • Good accuracy in gas-filled eyes. • Inter- and intraobserver variability (>30% varied by 2-3 mmHg), due to subjective nature of optical endpoint. • Assume error of 2 mmHg. E.M.B. Sept. 2000 Calibration: Wessels & Oh (1990) • Tested tonometers in ophthalmologists offices. • 19% outside range of manufacturers specifications (1mmHg of calibration), 4.5% > 2mmHg error. • Annual recalibration in 86% of instruments. • Practitioners who themselves performed calibration had the most accurate instruments. • Less than 15% knew how to perform calibration check. • Calibration here done 4 times/year E.M.B. Sept. 2000