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Skull and Spinal Cord Laboratory OBJECTIVES 1. To review the bony environment of the brain to appreciate the relationships of the brain to the bony cranium and the foramina thru which cranial nerves exit (or enter), and to appreciate the compartments inside the cranium created by the tentorium cerebelli and falx cerebri: supratentorial (containing cerebrum) and infratentorial (posterior fossa), providing certain natural routes for expanding tumors within these compartments. 2. To identify all of the cranial foramina that transmit cranial nerves, the ridges and protuberances where meninges attach, the cranial fossae and the lobes of the brain contained therein, and the impressions in the skull left by the various dural sinuses. The student is encouraged to review the skull and to see the actual spinal cord for orientation before moving on to the two-dimensional images of Chapter 3 “Skull, Meninges, and Spinal Cord” of the Digital Neuroanatomy PPT’s. Then the student can use the quiz mode of the same chapter of Digital Neuroanatomy Interactive CBI Program for self-test. DVD #1 contains a video on “Spinal Cord, Meninges, and Spinal Cord” for independent study in which most of the structures on the laboratory list are demonstrated. I. ANTERIOR CRANIAL FOSSA: above orbital plate of frontal bone, contains frontal lobe of the brain Crista galli- bony attachment of the falx cerebri Cribriform plate of ethmoid bone (exit of fibers of olfactory nerve, C.N. I) II. MIDDLE CRANIAL FOSSA: depression for temporal lobes Superior orbital fissure (exit of C.N. III, IV, ophthalmic V, and VI into orbit) Foramen rotundum (exit of C.N. maxillary V) Foramen ovale (exit of C.N. mandibular V) Foramen spinosum (middle meningeal artery supplying dura but coursing between dura and bone; note its impression on the lateral wall of the skull) Sphenoid bone greater and lesser wings, sella turcica (pituitary fossa), anterior clinoid processes (attachment of tentorium cerebelli) Optic foramen (exit of C.N. II) Cavernous sinus identify depression on sides of body of sphenoid bone, just lateral to sella turcica; review its contents (C.N. III, IV, VI, Ophthalmic. & Maxillary V, internal carotid artery) Temporal bone petrous portion (housing semicircular canals, cochlear duct, etc.), petrous ridge (attachment of tentorium cerebelli, containing superior petrosal sinus) Internal carotid foramen internal carotid artery enters cranial vault through cavernous sinus, carotid canal horizontal canal between external and internal carotid foramina through which internal carotid artery runs to enter the middle cranial fossa thru the internal carotid foramen III. POSTERIOR CRANIAL FOSSA: infratentorial compartment (depression below tentorium cerebelli for cerebellum and brainstem (midbrain , pons, medulla). Note: the brainstem (midbrain) connects to the cerebrum thru a large opening in the tentorium cerebelli (tentorial notch or incisure) Internal auditory meatus (exit of C.N. VII and VIII) Jugular foramen (exit of C.N. IX, X, and XI and internal jugular vein) Transverse sinus in attached margin of tentorium cerebelli Sigmoid sinus continues inferiorly from transverse sinus, below tentorium, empties into internal jugular vein (jugular foramen; origin of internal jugular vein) Confluence of sinuses: confluence of occipital, transverse, and superior sagittal sinuses Foramen magnum, spinal cord and vertebral arteries Hypoglossal foramen (exit of C.N. XII) * Link to Netter Image 1.17 * Link to Netter Image 1.18 IV. SPINAL CORD Dura mater, dural sac- extends to vertebral level S2; its inferior portion contains the lumbar cistern of the subarachnoid space with the cauda equina Arachnoid membrane- transparent; in fixed spinal cord it has shrunk over the surface of the cord, but in normal circumstances it would be pushed against the inside of the dura (lines the dural sac) by CSF pressure in the subarachnoid space Dorsal median sulcus Dorsal intermediate sulcus- above spinal level T6, it divides dorsal funiculus into two tracts Dorsolateral sulcus- exit of dorsal roots Dorsal roots- sensory roots entering spinal cord See interlacing (anastomosing) branches of the posterior spinal arteries across the dorsal cord Ventrolateral sulcus- exit of ventral roots Ventral roots- motor roots leaving spinal cord Spinal nerves Dorsal root ganglia- in outpocketings of dural sac; on dorsal root where dorsal & ventral roots merge to form the spinal nerve; in situ this is located right at the intervertebral foramen Ventral median fissure- deepest fissure, it contains the ventral (anterior) spinal artery Conus medullaris- tapering lower part of the cord; contains sacral and coccygeal spinal cord segments; this ends at vertebral level L2 Cauda equina- rootlets of dorsal and ventral roots from lower segments of the cord, descending to their intervertebral foramen of exit Pia mater- on surface of the cord; spinal cord blood vessels run in its loose upper surface (epi-pia) Denticulate ligament- about 20 pairs of these tooth-shaped attachments; a tiny filament coming off its tip attaches pia to the dura; covered by arachnoid; alternate between exits of spinal nerves; they anchor the cord laterally Filum terminale- extension of the pia below the conus medullaris; it extends to the bottom of the dural sac (S2) where it becomes surrounded with dura to form the coccygeal ligament which attaches to the coccyx, anchoring the cord inferiorly Identify features that distinguish: cervical, thoracic, lumbar and sacral levels of spinal cord Cervical enlargement Lumbar enlargement White and gray matter * Link to Netter Image 1.37 * Link to Netter Image 1.38A * Link to Netter Image 1.38B * Link to Netter Image 1.39A * Link to Netter Image 1.39B