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Name__________________________________ Date___________________________________ Block_____ Biology 12 Advanced Placement Mitosis and Meiosis Check-In Please ensure that you have all pages to the check-in. Good Luck, and remember you will do well! Part One: Multiple Choice 1. If there are 12 chromosomes in an animal cell in the G1 stage of the cell cycle, what is the diploid number of chromosomes for this organism? a. 6 b. 12 c. 24 d. 36 e. 48 2. A cell containing 92 sister chromatids at the start of mitosis would, as its completion, produce cells containing how many chromosomes? a. 12 b. 16 c. 23 d. 46 e. 92 3. If the haploid number for a species is 3, each dividing diploid cell will have how many chromatids at metaphase? a. 3 b. 6 c. 9 d. 12 e. 18 4. If liver cells of an animal have 24 chromosomes, the sperm cells would have how many chromosomes? a. 12 b. 24 c. 48 d. Twice the diploid number e. Half the haploid number 5. Regarding mitosis and cytokinesis, one difference between plants and animals is that in plants a. The spindle contains microfibrils in addition to microtubules, whereas animal spindles do not contain microfibrils. b. Sister chromatids are identical, but they differ from one another in animals c. A cell plate begins to form at telophase, whereas in animals a cleavage furrow is initiated at that stage d. Chromosomes become attached to the spindle at prophase, whereas in animals chromosomes do not become attached until anaphase e. Spindle poles contain centrioles, whereas spindle poles in animals do not 6. How do daughter cells at the end of mitosis and cytokinesis compare with their parent cell when it was in the G1 of the cell cycle? a. The daughter cells have half the amount of cytoplasm and half the amount of DNA b. The daughter cells have half the number of chromosomes and half the amount of DNA c. The daughter cells have the same number of chromosomes and half the amount of DNA d. The daughter cells have the same number of chromosomes and the same amount of DNA e. The daughter cells may have new combinations of genes due to crossing over 7. Cells that have stopped dividing and are growing are most likely to be in which stage? a. In the G2 phase of the cell cycle b. In the G1 phase of the cell cycle c. In the S phase of the cell cycle d. In the M phase of the cell cycle e. In the G0 phase of the cell cycle Answer the next TWO questions based on the following answers. Each answer may be used once, more than once, or not at all. a. G0 b. G1 c. S d. G2 e. M 8. Sister chromatids align in the middle of the cell 9. The shortest part of the cycle 10. The formation of a cell plate is beginning to form across the middle of a cell and nuclei are reforming at opposite ends of the cell. What kind of cell is this? a. b. c. d. e. An animal cell in metaphase An animal cell in telophase An animal cell undergoing telophase and cytokinesis A plant cell in metaphase A plant cell undergoing telophase and cytokinesis 11. The occurrence of centromeres uncoupling, sister chromatids are separated, and the two individual chromosomes move to opposite poles of the cell happens in which stage? a. Telophase b. Anaphase c. Prometaphase d. Metaphase e. Prophase 12. Spindle fibres can be described as a. Non-kinetochore and kinetochore microtubules b. Centre location of the sister chromatids c. Proteins that elongate from the nuclear envelope d. Structures that originate from the cell membrane e. Structures that help reform the nucleus 13. When comparing non-kinetochore and kinetochore microtubules, which of the following statements is TRUE. a. Non-kinetochore tubules are not true spindle fibres b. Non-kinetochore tubules are generated from the mitochondria c. Kinetochore tubules attach to kinetochore proteins and help align the sister chromatids during metaphase d. Kinetochore tubules attach to non-kinetochore proteins to elongate the cell during prophase 14. Which of the following statements is TRUE? a. Cyclin is always present in the cell b. Kinase is always present in the cell c. Cyclin levels depend on kinase levels d. Cyclin levels regulate kinase levels e. Cyclin is needed to trigger the cell passed the first checkpoint, G1 15. Cancer cells can best be described as a. Cells that do not respond normally to controls during cell division b. Cells that continue to grow as long as there are nutrients available c. Malignant cells that may metastasize and spread throughout the body d. Have larger nuclei e. All of the above 16. Which of the following is FALSE? a. Meiosis is often referred to as reduction division b. Meiosis creates genetic variation c. Meiosis occurs in prokaryotic cells d. Meiosis produces haploid daughter cells e. Gametes are produced during meiosis 17. Which of the following events occurs during prophase I of meiosis? a. Reduction in chromosome number b. Segregation of alleles of unlinked genes c. Synapsis and crossing over d. Duplication of chromatids e. Segregation of alleles of linked genes 18. You are genetically unique. This is a result of a. Sexual reproduction b. Genetic recombination c. Mutations that can occur d. All of the above 19. Which of the following is the term for a human cell that contains 22 pairs of autosomes and two X chromosomes? a. an unfertilized egg cell b. a sperm cell c. a male somatic cell d. a female somatic cell Answer the following question based on the diagram below 20. The diagram above represents a. Cytokinesis b. A haploid cell undergoing mitosis c. A haploid cell undergoing meiosis d. A diploid cell undergoing mitosis e. A diploid cell undergoing meiosis 21. A karyotype can be described as a. A type of spindle that elongates the cell b. A type of spindle that helps align sister chromatids c. A photomicrograph of an individual’s somatic cell chromosomes d. A photomicrograph of an individual’s somatic cell undergoing mitosis e. A photomicrograph of an individual’s sex cell undergoing meiosis 22. Which of the following is TRUE? a. In meiosis sister chromatids separate during anaphase I b. In meiosis sister chromatids separate during anaphase II c. In meiosis I cytokinesis occurs before metaphase II d. In mitosis metaphase is followed by prophase e. In mitosis centrioles are always present in all eukaryotic cells Part Two: Short Answer and Critical Thinking 1. Briefly explain why checkpoints are so important in regulating the cell cycle. _________________________________________________________ _________________________________________________________ _________________________________________________________ _________________________________________________________ 2. Compare and contrast between internal and external cues that help regulate the cell cycle. Please have two points per section. Internal External Part Three: Graphing, Analysis, and Interpretation 1. Using the following table and information come up with a line graph that highlights the data. Please remember to include a title and label the x/yaxis. You can choose to graph the number of cells in that phase or the percentage as one of your axis (you do not have to graph both). b) Explain/provide a reason for the data from the table/graph you just created. ______________________________________________________________ ______________________________________________________________ ______________________________________________________________ 2. Please provide a possible explain for the following graph below (up into 90 hours). ______________________________________________________________ ______________________________________________________________ ______________________________________________________________ ______________________________________________________________ ______________________________________________________________ 3. Develop one simple and one complex question that relates to meiosis. Your question could relate to abnormal chromosome number, error that can possibly occur, polyploidy organisms, etc. Simple Question: ______________________________________________________________ ______________________________________________________________ Brief Explanation: ______________________________________________________________ ______________________________________________________________ Complex Question (based off of your simple question) ______________________________________________________________ ______________________________________________________________ Explanation: ______________________________________________________________ ______________________________________________________________ ______________________________________________________________