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Number of people infected Number of people infected after exchange #4 if only one person is infected at the start start After Exchange #1 After Exchange #2 After Exchange #3 After Exchange #4 Least Possible Number of People Infected 1 2 4 4 6 Greatest Possible Number of People Infected 1 2 4 8 16 Assume that at the start of the activity that person A is infected and everybody else is susceptible. After Exchange #1: Possible number of people infected: 2 Greatest Possible Number Infected and Least Possible Number Infected: These numbers are the same and each is calculated by the fact that the infected person, A, exchanges fluids with a susceptible person, B, which causes 1 new infected person. At the end of exchange #1, the greatest number infected is 1 + 1 = 2. After Exchange #2: Possible number of people infected: 4 Greatest Possible Number Infected and Least Possible Number Infected: These numbers are the same and each is calculated by the fact that the infected person, A and B, exchanges fluids with a susceptible person, C and D respectively, which causes 2 new infected people. At the end of exchange #2, the greatest number infected is 2 + 2 = 4. After Exchange #3: Possible number of people infected: 4, 6, or 8 Greatest Possible Number Infected: This number is calculated by assuming that each of the four infected people exchanges fluids with a susceptible person, which causes 4 new infected people. At the end of exchange #3, the greatest number infected is 8. Least Possible Number Infected: Since nobody knows who is and who isn’t infected, it is possible that Person A exchanges fluids with Person D. However, since they are both already infected, their exchange of fluid does not cause a new infection. It is equally possible that Person B exchanges fluids with Person C. Again, since they are both already infected, their exchange of fluid does not cause a new infection. At the end of exchange #3, the least number infected is 3 + 1+ 0 = 4. After Exchange #4: Possible number of people infected: 6 – 16 even Greatest Possible Number Infected: This number is calculated by assuming that each of the eight infected people exchanges fluids with a susceptible person, which causes 8 new infected people. At the end of exchange #4, the greatest number infected is 16 Least Possible Number Infected: If only four people were infected at the end of exchange #3, then all four infected people must make contact with four susceptible people, leading to four new infections and a total of eight infected people. However, it turns out that, instead of four people, if six people were infected at the end of exchange #3, then it is possible that these six people can exchange fluids amongst themselves without infecting any new susceptible people. Thus the least number of infected people after exchange #4 is 6 people.