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Biochemistry (CHE 450) MW 11:00-12:45 PM SCC D-109A Instructor: Dr. Noel Sturm, NSM D-323, (310) 243-3383. Office Hours: M 1:00-2:30PM; T 10:30-1:00PM, "Chat" Room T 6:30-8:30PM E-Mail: [email protected] Course Organization and Policies: 1. Prerequisites: (a) General Chemistry (1 year) and (b) Organic Chemistry w/ Laboratory (1 year or a 1 semester survey course) and (c) Quantitative Analysis (may be taken concurrently w/ Biochemistry 451L). 2. Suggested Text: "Harper's Biochemistry", Murray; Granner; Mayes; Rodwell; Appleton & Lange; twenty-sixth edition, 2003; ISBN: 0071389016. 3. Lecture Notes: The lecture notes are available on-line, arranged via lecture topic, at: http://www.gravitywaves.com/chemistry. It is suggested that you bring a printed copy of the lecture notes with you to class to facilitate learning. Examination questions will be derived directly from lecture material, i.e. class attendance is essential to do well in this course. 4. Examinations: There will be four examinations (see syllabus for specific dates) each worth 100 points. Absolutely NO make-up exams will be given. 5. Daily Quizes: There will be a five minute daily quiz (except on exam days) from 11:00 to 11:05 AM. These quizes will total 100 points towards the final grade (equal to one exam grade). No make-up quizes will be given, students arriving late will receive a zero for that days quiz, however the five lowest quiz scores will be dropped. If you miss a daily quiz it will count toward one of the five dropped quiz scores. Regular on time attendance is essential to do well in this class. 6. Final Exam: The final exam, which will be multiple choice and comprehensive, is on Wednesday, December 14, 11:30-1:30 PM. 7. Homework: Weekly homework will be assigned and should be printed from the web site. Short answers/definitions for the Learning Objectives (Homework) will be collected. The objectives are designed to help you focus and assimilate the material presented. See syllabus for specific due dates. Penalty points may be assigned for missing or late homework. 8. The Goal of this course is to understand and outline Proteins, Enzymes, Vitamins, Membranes and all of the Carbohydrate Metabolic Pathways. 9. Grading Criteria: Letter grades will be assigned on the following basis. Grades are not curved. Daily Quizes = 100 pts Four Exams @100 pts = 400 pts Final Exam = 100 pts Homework = Required Grade A B+ BC D+ F Percentages 100-91 88-87 80-79 76-71 68-67 59-0 Grade AB C+ CD Percentages 90-89 86-81 78-77 70-69 66-60 10. Case Studies (CS) /Clinical Correlates: Related directly to the general biochemical principles being taught are intended to give "real-life" significance to the biochemistry experience and should be printed from the web site. 11. Course Description: The chemistry of amino acids and proteins; the chemistry and metabolism of carbohydrates and lipids; energetics in living systems. The course is taught with a medical emphasis and covers peptides, proteins, myoglobin/hemoglobin, enzymes, vitamins, catecholamines and metabolism, as well as, clinical correlates and case studies. 12. Academic Integrity Statement: A university is a community of learners bonded together by the search for knowledge; the pursuit of personal, social, cultural, physical, and intellectual development; and the desire for the liberating effects of an advanced education. California State University, Dominguez Hills (CSUDH) has a culture--an academic culture--shared with other universities and colleges across the nation. Integral to that culture is a set of values such as academic freedom, dedication to teaching and learning, diversity, civility toward others, and academic integrity. Academic integrity is of central importance in the university community and involves committed allegiance to the values, the principles, and the code of behavior held to be central in that community. Integrity concerns honesty and implies being truthful, fair, and free from lies, fraud and deceit.