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About AICR OUR VISION: We want to live in a world where no one develops a preventable cancer. OUR MISSION: We champion the latest and most authoritative scientific research from around the world on cancer prevention and survival through diet, weight and physical activity, so that we can help people make informed lifestyle choices to reduce their cancer risk. We have contributed over $105 million for innovative research conducted at universities, hospitals and research centers across the country. Find evidence-based tools and information for lowering cancer risk, including AICR’s Recommendations for Cancer Prevention, at www.aicr.org. Reduce Your Risk of COLORECTAL CANCER About the Continuous Update Project As the U.S. charity in the World Cancer Research Fund network, we contribute to the Continuous Update Project (CUP), an ongoing analysis of global scientific research into the link between diet, physical activity, weight and cancer. The CUP produces periodic reports on the state of the evidence linking various lifestyle factors to risk of specific cancers. These reports will inform a major update of our Recommendations for Cancer Prevention scheduled for 2017. AICR Guidelines for Cancer Prevention Questions and Answers Contact Us CancerPrevention: Together We Can is an initiative of the American Institute for Cancer Research. Visit www.aicr.org/can-prevent “WHAT IS COLORECTAL CANCER?” “IS COLORECTAL CANCER INHERITED?” Colorectal cancer is a tumor caused by abnormal division of the cells lining the large intestine—the end of the digestive tract. This is where waste material is stored and where you preserve water before you eliminate waste Most colorectal cancer occurs in people who have no family history of the disease. According to the National Cancer Institute, only 10–30 percent of cases of colorectal cancer occur in people who do have a family history. Only about 5 percent of all cases are associated with known inherited gene mutations. Colorectal cancer takes many years to develop. Often, harmless growths (called “polyps”) form on the lining of the large intestine before colorectal cancer is diagnosed. Research suggests that 50 percent of colorectal cancers could be prevented by adopting healthy habits. “HOW CAN I REDUCE MY RISK OF COLORECTAL CANCER?” Research shows that food and nutrition, along with regular physical activity, can play a very important role in preventing colorectal cancer. According to AICR’s expert report and its updates, healthy changes in your diet and lifestyle can reduce your risk of developing colorectal cancer: The choices you make about food, physical activity and weight management can reduce your chances of developing cancer. • Choose mostly plant foods, limit red meat and avoid processed meat. Photo © Bigstock • Be physically active every day in any way for 30 minutes or more. Limit sedentary habits, like watching television. “HOW COMMON IS COLORECTAL CANCER?” • Aim to be a healthy weight throughout life. And always remember—do not smoke or chew tobacco. Make a donation online at www.aicr.org; write to AICR, 1759 R Street, NW, P.O. Box 97167, Washington, DC 20090-7167; or include a bequest in your will. For more information, contact our Gift Planning Department at 1-800-843-8114. AICRBlog ©American Institute for Cancer Research Latest update, April 2015 Stopping Cancer (Colorectal).indd 1 @aicrtweets Facebook E54-BHC Stopping Cancer Series Cover Photos © Fotolia, © Getty Images Follow us on In the United States, colorectal cancer is the third most common cancer among adults and the second leading cause of death from cancer. Approximately 133,000 new cases are diagnosed annually in the United States, and close to 50,000 deaths are attributed to it each year. In addition to a healthy diet and daily activity, get regular screenings by a doctor beginning at age 50. “DOES EARLY DETECTION MAKE A DIFFERENCE?” Yes. For patients whose cancers are found very early (stage 1), the five-year survival rate is 90 percent. But only 40 percent of colorectal cancers are diagnosed at an early stage due to under-use of screening. Survival rates drop dramatically after cancer has spread to other parts of the body. Early detection is very important. 4/21/15 11:33 AM 1. Physical activity—of all types—decreases colorectal cancer risk. Be physically active for at least 30 minutes every day. As your fitness improves, aim for 60 minutes. •Do some moderate activities such as swimming, brisk walking or energetic household chores. •Try to incorporate vigorous activities like aerobics and jogging. •Shorter bouts of physical activity (10 or 15 minutes) count, too. • Limit high-calorie foods including fast food and sugary drinks. • Keep an eye on portion sizes and think before taking second helpings. • Be physically active every day. Photos © Fotolia, © Getty Images 3. Convincing evidence links alcohol with increased risk of colorectal cancer. To decrease your risk, limit alcoholic drinks to one drink per day for women and two drinks per day for men, if you choose to drink at all. Stopping Cancer (Colorectal).indd 2 •a change in bowel habits, like prolonged diarrhea or constipation •feeling that the bowel doesn’t empty completely •blood in the stool (either bright red or very dark) or rectal bleeding •stools smaller in width than usual •general abdominal discomfort (like frequent gas pains, bloating, fullness or cramps) •abnormal weight loss or decreased appetite •abnormal fatigue and weakness 1) Rate your risk. Anyone can get colorectal cancer. But higher risk factors include: •being over 50 years of age •personal history of other cancer or colon polyps 5. Eating plenty of high-fiber foods decreases colorectal cancer risk. •Aim for 25–38 grams of dietary fiber daily, depending on your age and gender. Some research suggests that for cancer prevention, it may be best to aim for at least 30 grams a day. Eat a diet rich in vegetables, fruits, whole grains and beans to increase your fiber intake. •personal history of inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis) • cigarette smoking • diet low in fiber • diet high in red meat and processed meat •alcohol consumption, especially more than 2 drinks per day • lack of physical activity •overweight, particularly excess fat around the midsection • having type 2 diabetes •Eat no more than 18 oz. of beef, pork or lamb per week. •In general, avoid processed meats. This includes meat preserved by smoking, curing, salting or with chemical preservatives, such as bacon, ham, salami, sausage and hot dogs. Save them to eat on special occasions—a slice of ham on a holiday or a hot dog at a baseball game. If you have any of the following symptoms, you should check with your doctor: Early-stage colorectal cancer often produces no symptoms. Regular screenings are very important because successful treatment depends on early detection. •family history of colorectal cancer 2. Red meat and processed meat are a cause of colorectal cancer. •Keep your portions small (3 oz. per meal—the size of a deck of cards). Be Alert To Possible Symptoms Early Detection Saves Lives 2) Have regular exams by a physician. Food Amount Fiber (grams) 1 slice whole-wheat bread 2 1 ounce high-fiber breakfast cereal 5 1 cup beans 7 ½ cup chopped vegetables 2–4 1 whole medium or ½ cup chopped or small-sized (berries) fruit 2–3 Beginning at age 50, you should have screening tests performed, even if you have no symptoms of colorectal cancer. People with one or more risk factors should begin screening at an earlier age and undergo screening more frequently. Types of exams include colonoscopy, DNA stool test and rectal exam. For more details about screenings, visit the National Cancer Institute at www.cancer.gov/cancertopics/types/colorectal – AICR/WCRF, Policy and Action for Cancer Prevention Photo © Fotolia AICR’s report and its updates found that eating a healthy diet and being physically active daily are the most important choices you can make to reduce your risk of colorectal cancer. 4. Too much body fat—including fat around the midsection—increases your risk. To stop weight gain or lose weight: Q: How many colorectal cancers don’t have to happen? Photo © Fotolia What to Know Diet and Lifestyle… Important Risk Factors You Can Control A: One-half (50 percent) of all cases. – www.aicr.org 4/21/15 11:33 AM