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4/22/16 Eye Bio 40B Dr. Kandula External Anatomy of Eye Accessory Structures l l l l l l Eyebrows Levator Palpebrae Superioris - opens eye Eyelashes Ciliary glands – modified sweat glands Small sebaceous glands Sty is inflamed ciliary glands or small sebaceous glands 1 4/22/16 Terms: Lacrimal gland and duct Surface of eye Lacrimal puncta Lacrimal sac Nasolacrimal duct Nasal cavity Tears / Lacrimal fluid a watery physiologic saline, with a plasma-like consistency, l contains the bactericidal enzyme lysozyme; l it moistens the conjunctiva and cornea, l provides nutrients and dissolved O2 to the cornea. l Extrinsic Muscles of the Eye: Lateral/medial rectus Superior/inferior rectus Superior/inferior oblique Important to know actions and nerve supply in table 2 4/22/16 Extrinsic Eye Muscles • Eye movements controlled by six extrinsic eye muscles Four recti muscles § Superior rectus – moves eyeball superiorly supplied by Cranial Nerve III § Inferior rectus - moves eyeball inferiorly supplied by Cranial Nerve III § Lateral rectus - moves eyeball laterally supplied by Cranial Nerve VI § Medial rectus - moves eyeball medially supplied by Cranial Nerve III Extrinsic Eye Muscles Two oblique muscles rotate eyeball on its axis § Superior oblique rotates eyeball inferiorly and laterally and is supplied by Cranial Nerve IV § Inferior oblique rotates superiorly and laterally and is supplied by Cranial Nerve III Convergence of the Eyes l l l l l Binocular vision in humans has both eyes looking at the same object As you look at an object close to your face, both eyeballs must turn inward. convergence required so that light rays from the object will strike both retinas at the same relative point extrinsic eye muscles must coordinate this action 3 4/22/16 Internal Eye Anatomy Tunics of eye Fibrous tunic – outer layer Vascular tunic / uvea – middle layer l Nervous tunic / retina – inner layer l l Fibrous Tunic sclera cornea 4 4/22/16 Sclera “White” of the eye, covers posterior ¾ of the eye l Dense irregular connective tissue layer -collagen & fibroblasts l Provides shape & support l At the junction of the sclera and cornea is an opening (scleral venous sinus) l Posteriorly pierced by Optic Nerve (Cr.N.II) l Cornea Transparent, avascular Nourished by tears & aqueous humor l Helps focus light (refraction) l Astigmatism -corneal surface wavy so parts of image out of focus 3 layers l l Transplants: common & successful; no blood vessels so no antibodies to cause rejection Middle vascular tunic or uvea Choroid Ciliary body ciliary muscle & ciliary process l Iris - radial muscle & circular muscle - pupil l l 5 4/22/16 Choroid: a network of blood vessels that supply oxygen and nutrients to the tissues of the eye. l located deep to the sclera l contains a pigmented layer (melanin) that helps absorb excess light and prevents internal reflection l Ciliary Body anterior to the choroid is a circular structure called the "ciliary body." l ciliary body has ciliary muscles that act on suspensory ligaments which suspend the lens in the correct position. l Ciliary body is also made up of a ciliary process that makes a fluid called aqueous humor l Suspensory Ligaments The suspensory ligaments are either taut or relaxed based on the action of the ciliary muscles. l The tension on the ligaments changes the shape of the lens, depending on the distance of the object being viewed. l This process is called "accommodation". l 6 4/22/16 Accommodation Problems Internal Eye Anatomy Iris l l l l l Colored part of the Eye it is the most anterior portion of the vascular tunic Made up of radial muscle & circular muscle ( intrinsic muscles of eye) Controls the amount of light entering the eye the opening in the middle of the iris is called the "pupil," which appears as the dark center of the eye. 7 4/22/16 Iris l l l l The iris either dilates or constricts the pupil to regulate the amount of light entering the eye. In bright light the pupil will be small, but in dim light the pupil will be very large to let in as much light as possible. Constriction of pupils - contraction of the circular fibers – parasympathetic control Dilation of pupils - contraction of radial fibers – sympathetic control Inner sensory tunic/retina Posterior ¾ of eye ball only anterior margin – ora serrata retina (rods only) optic disc – attachment of optic nerve / blind spot, no photoreceptors fovea centralis – near the middle of the retina, highest concentration of cones and region of highest visual acuity. 8 4/22/16 Inner sensory tunic/retina superficial layer of pigment epithelium ( melanin): l non-visual portion l absorbs stray light & helps keep image clear deeper layer of neurons - rods/cones are photoreceptor layer - bipolar neuron layer - ganglion cell layer Photoreceptors on Retina 9 4/22/16 Rods and Cones/ Photoreceptors Rods----rod shaped cells l shades of gray in dim light l nocturnal vision – black and white vision, great sensitivity in dim light l 120 million rod cells l discriminates shapes & movements, distributed along periphery of retina Rods and Cones/ Photoreceptors Cones----cone shaped cells l sharp, color vision at all higher light intensities l 6 million l Fovea centralis – widest distribution at center of retina Lens focuses image on retina suspensory ligament and ciliary muscles control curvature to focus images on retina l divides interior of eyeball into anterior cavity and posterior cavity l l 10 4/22/16 Flattened (less convex) for distant images Rounded (more convex) for close images Anterior cavity (anterior to lens) filled with aqueous humor l produced by ciliary body l continually drained by scleral venous sinus l replaced every 90 minutes l drainage of aqueous humor from eye to bloodstream Glaucoma l increased intraocular pressure that could produces blindness l problem with drainage of aqueous humor Posterior cavity (posterior to lens) filled with vitreous humor (jellylike) Holds retina in place l formed once during embryonic life l floaters are debris in vitreous of older individuals l l 11 4/22/16 Visual field of left eye Temporal half Visual field of right eye Nasal half Nasal half Temporal half Left eye Right eye Nasal retina Temporal retina 1 Nasal retina 3 4 Optic 4 2 2 tract Midbrain Temporal retina 1 3 5 5 Midbrain Lateral geniculate nucleus of the thalamus Optic radiations 6 6 Optic radiations Primary visual area of cerebral cortex (area 17) in occipital lobe Left eye and its pathways Right eye and its pathways Cortex regions responsible for vision Left occipital lobe receives visual images from nasal 1/2 of the right eye and temporal 1/2 of the left eye l Right occipital lobe receives visual images from nasal 1/2 of the left eye and temporal 1/2 of the right eye l Internal Structures of Eye Inner sensory tunic/retina pigment epithelium rods/cones are photoreceptor Rods: Nocturnal vision – black and white vision, great sensitivity in dim light Cones: color vision at all higher light intensities optic disc – attachment of optic nerve / blind spot fovea centralis – highest concentration of cones 12 4/22/16 Eye terms l l l l l l Lens is convex. More convex to see close, less convex to see distant. UV light damage to lens = cataract Myopia = nearsighted, fix with concave lens Hypermetropia = farsighted, fix with convex lens Rods detect black/white in dim light, Cones detect color in bright light Glaucoma is buildup of fluid pressure in eye Key 1. superior oblique 2. superior rectus l 3. medial rectus l 4. lateral rectus l 5. lateral rectus l 6. inferior oblique l l 13 4/22/16 Choroid, Ciliary Body, Iris and Pupil 14 4/22/16 15