Download AMIODARONE (CORDARONE)

r*PHYSORDE*r
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HALIFAX HEALTH
303 N. Clyde Morris Blvd., Daytona Beach, FL 32114
1041 Dunlawton Ave., Port Orange, FL 32127
"X" IN BOX
FOR STAT MED
PHYSICIAN’S ORDERS
Patient Name
Adm. Date
Date of Birth
MR #
Dr.
Age
Visit #
AMIODARONE (CORDARONE)
(CORDARONE)
ALLERGIES:
Page 1 of 1
HIGH RISK / DO NOT USE ABBREVIATIONS: U, IU, MS, MSO4, MgSO4, QD, QOD.
ALWAYS WRITE OUT INTENDED MEANING AND USE METRIC. DO NOT USE A ZERO AFTER A DECIMAL; ALWAYS USE A ZERO BEFORE A DECIMAL.
DATE
TIME
CK’D
(✔)
❑
X CHECK BOX TO INITIATE ORDER
1. Do not start Amiodarone in complete heart block or type II second degree heart block unless functional
pacemaker in place
Note: Check box if bolus needed
❑ Bolus 150 mg Amiodarone IV in 100 ml D5W (1.5 mg/ml) over the first 10 minutes
Set IV pump to run at 600 ml/hour and volume to be infused = 100 ml
Bolus must be hung within 2 hours of preparation
Discard if not used
2. ❑
X Call Pharmacy to mix Amiodarone infusion of 900 mg diluted in 500 ml of D5W (polyolefin bag)
(1.8 mg/ml) for continuous infusion over 24 hours with an inline filter as follows:
• Infuse 1 mg/min. over 6 hours (set infusion pump rate at 33 ml/hour and volume to be infused = 200 ml)
• Then reduce to 0.5 mg/min. over the remaining 18 hours (set infusion pump rate at 17 ml/hour and
volume to be infused = 300 ml)
Cordarone Guidelines:
1.) IV Cordarone is indicated for initiation of treatment and prophylaxis for recurring ventricular fibrillation and
hemodynamically unstable ventricular tachycardia in patients refractory to other therapy
2.) Do not use in patient with known hypersensitivity to any component of IV Cordarone, or in patients with
cardiogenic shock, marked sinus bradycardia, and second or third degree AV block unless a functioning
pacemaker is available
3.) Complete assessment, baseline vital signs and rhythm strip documentation before medication is
administered
4.) It is preferred that IV Cordarone be administered through a central venous catheter dedicated line
5.) Mix in D5W only
6.) An inline filter should be used during administration
7.) Cordarone infusion will be mixed by Pharmacy in polyolefin bags
8.) Monitoring Therapy:
• Vital Signs: blood pressure, pulse, and respirations will be documented a minimum of every
15 minutes x 4 when intravenous push/continuous infusion is initiated or dosage is changed,
then every 4 hours during continuous infusion
9.) Most Common Drug Incompatibilities (do not give through the same IV line):
Heparin
Quinidine
Sodium Bicarbonate
Aminophylline
Furosemide
Cefazolin Sodium (Ancef)
10.) Common Drug Interactions:
Digoxin = increased digoxin levels
Beta Blockers = increased effects on both drugs
Warfarin = increased warfarin effect
Calcium Channel Blockers = increased effect on both drugs
11.) Side Effects: hypotension, headache, dizziness, bradycardia, AV conduction abnormalities, and flushing
12.) If significant adverse effects, particular conduction disturbances and/or exacerbation of arrhythmias
occur, STOP the infusion and notify physician
13.) If amiodarone oral therapy is ordered, it is generally initiated with the first dose given immediately
following discontinuation of the infusion
14.) Oral amiodarone therapy yields lower serum drug levels than with IV therapy
Physician Signature:__________________________________________ Dictation #:__________________
PHYSICIANS: PLEASE REMEMBER TO USE YOUR DICTATION NUMBER WITH YOUR SIGNATURE.
PHYS ORDER
ALL ORDERS TO PHARMACY
HMC − 1565 − 2/10