Download BOVINE PRODUCT GUIDE VACCINES Modified Live Vaccines

VACCINES
Modified Live Vaccines
Express® FP vaccines
Presponse SQ vaccines
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Contains M. haemolytica
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Single dose
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Unique adjuvant system, enhancing immune response
Approved for the prevention of persistently infected
calves caused by bovine viral diarrhea virus types 1 and 2
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Strongest BVD label claim on the market
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Ready-to-use, no mixing required
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Proven protection based on disease challenge models
and backed by independent published research
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Low dose (2 mL) SQ administration
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Annual re-vaccination required
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Rapid onset of immunity, meaning effective immune
response quickly after vaccination and proved protection
against IBR and BVD within days
Allows for whole herd vaccination – approved for use in
previously-vaccinated pregnant cows and heifers, and
calves nursing pregnant females
Demonstrated 12-month duration of immunity against
IBR-induced abortions and against disease including
persistently infected calves caused by BVD types 1 and 2
Prevents renal colonization and urinary shedding of
Leptospira borgpetersenii serovar hardjo
(type hardjo-bovis)
Broad reproductive and respiratory virus disease
coverage containing IBR, BVD type 1 and 2, PI3 and
BRSV
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No minimum age restriction
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Convenient combinations available with 5-way Lepto,
H. somni or both, and Vibrio-Lepto 5
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Zero milk withhold, 21 days slaughter withdrawal
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Annual re-vaccination required
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Calves born from Express® vaccinated cows are
eligible for coverage under the Express® Verified BVD PI
guarantee
Broad coverage – BVD Types 1 and 2, IBR, BRSV and PI3
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Single dose BRSV protection. Provides the protection and
convenience of one dose technology
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Unique adjuvant system, enhancing the animal’s
response to the vaccine for great protection
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Pyramid® + Presponse® combines the two highly
efficacious vaccines in one easily administered dose,
reducing handling, stress and cost
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Allows for viral and bacterial respiratory and clostridial
protection in only two injections
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No minimum age restrictions
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Whole herd claim allows the flexibility to vaccinate
pregnant cows and heifers, or calves nursing pregnant
cows, if previously vaccinate according to label
instructions
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Demonstrated economic advantages in a head-to-head
feedlot trial versus Bovi-Shield Gold®1
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Zero milk withhold, 21 days slaughter withdrawal
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Annual re-vaccination required
Killed Vaccines
Triangle®
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A leading killed viral vaccine – provides the confidence
of proven protection
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Contains killed IBR, BVD type 1 and 2, PI3 and BRSV
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Flexible to use – Can be used in all ages and stages of
production
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Unique dual adjuvant system – Minimizing injection site
reactions, while maximizing immune system recognition.
Demonstrated advantages by limiting milk drop post
vaccination
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Milk withdrawal: Milk must not be used for food for the
first 84 hours after calving. Use no later than 30 days
prior to calving
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Slaughter withdrawal: 42 days after latest infusion
Dry-Clox® (cloxacillin benzathine)
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Dry-Clox® – Dry cow treatment providing bactericidal
activity against gram-positive bacteria
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Bactericidal against susceptible organisms including
Strep agalactiae and Staph aureus, including
penicillin-resistant strains of Staph aureus
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Labelled for intramammary infusion in dry cows only at
the time of drying off. Use no later than 30 days prior to
calving
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Dry-Clox® has prolonged antibiotic activity due to the
low solubility of cloxacillin benzathine and the slow
release gel base
Metacam® 20 mg/mL Solution for Injection
(meloxicam)
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Takes advantage of the Opti-Sert® tip which aids in
partial insertion
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Metacam® provides proven and effective pain relieve to
helps animals recover faster from dehorning or diarrhea
and return to full performance. Metacam® improves
calves’ appetite and growth.
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Dosage: Infuse a 10 mL syringe (500 mg of cloxacillin
activity per syringe) in each quarter once, after quarter
has been completely milked out
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For the treatment of inflammation and pain associated
with acute clinical mastitis.
Treated animals must not be slaughtered for use in food
for at least 30 days after the latest treatment with this
drug
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For use in sheep and lambs for the alleviation of pain
and inflammation.
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For use in swine for to reduce the symptoms of
lameness and inflammation.
Milk taken from treated cows which calve within
30 days of infusion must not be used as food until the
unexpired remainder of the 30 days has elapsed
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Metacam®’s long half-life and duration of action
means that a single dose is required to relief pain for
several days
Anti-Infectives
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Metacam® can be administered as a single
subcutaneous or intravenous injection with a low
injection volume
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Bio-MycinTM 200 is a sterile, ready-to-use, broad
spectrum injectable antibiotic
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Approved for use in beef cattle and swine
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Metacam® combines animal welfare and profitability:
Any condition or procedure that affects the comfort or
well-being of an animal has an impact on productivity.
Metacam®, by improving the well-being of the animal
treated, enables you to minimize losses or even largely
maintain profitability
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Approved for treatment of Bacterial pneumonia,
Pasteurellosis (associated with shipping fever complex),
Footrot caused or complicated by bacteria susceptible to
oxytetracycline, and for the treatment of Pinkeye caused
by Moraxella bovis in Cattle
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Milk withdrawal: 96 hours
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Sustained antibiotic blood level activity over 3-5 days in
cattle following a single treatment
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Sub-Q or IM administration
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Formulated as a patented non-toxic, non-irritating
injectable solution
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Dosage for cattle is 1 mL / 10 kg body weight
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Slaughter withdrawal for Cattle:
Presponse® HM vaccines
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Contains both M. haemolytica and P. multocida
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Single dose
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Annual re-vaccination required
PHARMACEUTICALS
NSAIDs
Pyramid® FP Vaccines
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Dosage: Infuse a 10 mL syringe (300 mg of cephapirin
activity per syringe) in each quarter once after quarter
has been completely milked out
Presponse® SQ vaccines
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•
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Lactating cow tubes
Cefa-Lak® (cephapirin sodium)
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Cefa-Lak® is a cephalosporin which has a wide range of
antimicrobial activity against gram-positive and
gram-negative bacteria
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Bactericidal against susceptible organisms including
Strep agalactiae and Staph aureus including strains
resistant to penicillin
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For lactating cows only
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Treatment is completed in a single day (2 treatments
12 hours apart)
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Cefa-Lak® is a first generation cephalosporin and of less
concern to Health Canada with regard to antimicrobial
resistance issues in human medicine than
third-generation cephalosporins
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Dosage: Infuse a 10 mL syringe (200 mg of cephapirin
activity per syringe) once the quarter has been
completely milked out. Repeat only once in 12 hours
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Milk withdrawal: 96 hours after last treatment
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Slaughter withdrawal: 4 days after the last treatment
Bio-MycinTM 200 (oxytetracycline)
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IM injection: 28 days for cattle
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SQ injection: 48 days
Polyflex® (ampicillin for injectable suspension USP,
veterinary)
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Polyflex® is a broad-spectrum penicillin which has
bactericidal activity against a wide range of common
gram-positive and gram-negative bacteria
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Labeled for bacterial pneumonia, shipping fever
complex and enteritis caused by Staphylococcus sp and
Escherichia coli susceptible to ampicillin in Cattle
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Milk taken from treated animals during treatment and
within 48 hours after the latest treatment must not be
used as food
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Treated animals must not be slaughtered for use in
food for at least six (6) days (CATTLE) after the latest
treatment with this drug
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Convenient combinations available with 5-way lepto and
H. somni in varying combinations
Dry cow tubes
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May be administered to nursing calves, pregnant and/or
lactating cows
Cefa-Dri® (cephapirin benzathine)
Anti-parasiticides
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Annual re-vaccination required
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Cefa-Dri® is a cephalosporin which has a wide range of
antimicrobial activity against gram-positive and
gram-negative bacteria
Cydectin® Pour-on for Beef and Dairy Cattle
(moxidectin)
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Approved for lactating dairy cattle
Clostridials
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Bactericidal against susceptible organisms; it is known
to be highly active against Strep agalactiae
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Zero milk withhold and 15 day meat withdrawal
Fermicon 7/Somnugen®
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Long-acting persistence of Cydectin® Pour-On controls a
broad range of internal and external parasites
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Controls lice, grubs and mange mites
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7-way plus H. somnus combination
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5 mL IM or SQ administration
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Initial vaccination followed by booster in 21 to 28 days
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Annual re-vaccination required
PREVENTION WORKS.
Labeled for intramammary infusion in dry cows only at
the time of drying off. Use no later than 30 days prior to
calving
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Takes advantage of the Opti-Sert® tip which aids in
partial insertion
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Cefa-Dri® has prolonged antibiotic activity due to the low
solubility of cephapirin benzathine and the slow release
gel base
BOVINE PRODUCT GUIDE
B O E HRINGE R
INGE L HE IM
( C ANAD A )
LT D.
BOEHRINGER INGELHEIM (CANADA) LTD.
Cattle Vaccines Product Chart
Administration
nn
2 mL
SQ
Express® FP 10
nnnnn
n
nn
2 mL
SQ
Express 10 / Somnugen®
nnnnnn
n
nn
2 mL
SQ
Express® FP 5-VL5
nnnnn
nn
nn
2 mL SQ or IM
Express® Feedlot
nnnnn
n
2 mL
Express® Yearling
nnn
n
2 mL SQ or IM
Pyramid® FP 5 +
Presponse® SQ
nnnnn
Pyramid® FP 5
nnnnn
Pyramid® FP 10
nnnnn
Pyramid® 2 + Type II BVD
nnn
n
5-way Lepto
nnnnnn
P. multocida
Express 5 / Somnugen®
H. somnus
SQ
BRSV
2 mL
PI3
nn
IBR
nnnnn
BVD II
Express® FP 5
BVD I
Dosage
Single-Dose BRSV
Respiratory Protection
BVD Fetal Protection
7-Way Clostridial
Vibrio (C. fetus)
M. haemolytica
VACCINE ANTIGENS AND FEATURES
n
n
SQ
nnn
2 mL
SQ
nnn
2 mL
SQ
nnn
2 mL
SQ
nn
2 mL
SQ
Presponse® HM
nn
2 mL
IM
Presponse® SQ
n
2 mL
SQ
Triangle® 5
n
nnn
Triangle® 10
nnnnn
5 mL SQ or IM
n
n
Fermicon 7 / Somnugen®
5 mL SQ or IM
n
5 mL SQ or IM
SQ: Subcutaneously | IM: Intramuscularly
Mastitis Products
Cefa-Lak®
Dry-Clox®
LACTATING COW
TREATMENT
NSAID
Cefa-Dri®
Metacam®
DRY COW TREATMENT
Anti-parasiticides
Anti-Infectives
Polyflex®
Bio-Mycin™ 200
Cydectin® Endectocide
Fermicon/Somnugen®
Presponse®
Cydectin®
Polyflex®
Bio-Mycin™ 200
For more information, please contact your Boehringer Ingelheim (Canada) Ltd. Territory Manager or call Customer Care at
1-800-567-1885. For technical support on any of our products, please call 1-877-565-5501.
Reference: 1. Bryant TC, Rodgers KC, Stone ND, Miles DG. 2008. Effect of viral respiratory vaccine treatment on performance, health and carcass traits of auction-origin feeder steers.
Bovine Practitioner 42 (1):98-103.
Express and Metacam are registered trademarks of Boehringer Ingelheim Vetmedica GmbH. Pyramid, Triangle, Fermicon 7/Somnugen, Prepsonse, Cefa-Lak, Cefa-Dri, Dry-Clox,
Bio-Mycin and Polyflex are registered trademarks of Boehringer Ingelheim Vetmedica, Inc. © 2016 Boehringer Ingelheim (Canada) Ltd. All rights reserved.