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Core Resources for TB Medical Consultants
You can access the Core TB Resources below by pressing CTRL+left click on the web links
(Requires Internet connection)
National Guidelines
1) Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in HealthCare Settings, 2005 MMWR 2005; 54 (No. RR-17) 1-141.
http://www.cdc.gov/mmwr/pdf/rr/rr5417.pdf
a. Erata (September 25, 2006)
http://www.cdc.gov/tb/pubs/mmwr/Errata09-25-06.pdf
b. Risk Assessment Worksheet (September 27, 2006)
http://www.cdc.gov/tb/pubs/mmwr/Maj_guide/AppendixB_092706.pdf
c. Additional FAQs (February 12, 2007)
http://www.cdc.gov/tb/pubs/mmwr/Maj_guide/faqsGuidelines.htm
2) Guidelines for the Investigation of Contacts of Persons with Infectious Tuberculosis:
Recommendations from the National Tuberculosis Controllers Association and CDC.
MMWR 2005; 54 (No. RR-15, 1-37)
http://www.cdc.gov/mmwr/pdf/rr/rr5415.pdf
3) Guidelines for Using the QuantiFERON®-TB Gold Test for Detecting Mycobacterium
tuberculosis Infection, United States MMWR 2005; 54 (No. RR-15) 49-55
http://www.cdc.gov/mmwr/pdf/rr/rr5415.pdf
QuantiFERON®-TB Gold Testing Services: This list of institutions that have agreed
to provide QFT testing services to outside physicians and laboratories can be accessed
at http://www.quantiferon.com/contacts_usca.php
4) Controlling Tuberculosis in the United States: Recommendations from the American
Thoracic Society, CDC, and the Infectious Diseases Society of America.
MMWR 2005; 54 (No. RR-12) http://www.cdc.gov/MMWR/PDF/rr/rr5412.pdf
5) Tuberculosis Associated with Blocking Agents Against Tumor Necrosis Factor - Alpha
- California, 2002–2003 - MMWR 2004; 53 (No. 30)
http://www.cdc.gov/MMWR/PDF/wk/mm5330.pdf
6) Treatment of Tuberculosis - MMWR 2003; 52 (No. RR-11)
http://www.cdc.gov/MMWR/PDF/rr/rr5211.pdf
a) Erata (January 7, 2005) – MMWR 2005;53 (No. 51-52): 1203
http://www.cdc.gov/mmwr/PDF/wk/mm5351.pdf
b) Hepatotoxicity of Antituberculosis Therapy: An Official ATS Statement – Am J
Respir Crit Care Med; 2006;174:935-972
http://www.thoracic.org/sections/publications/statements/index.html
7) Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection - MMWR
2000; 49 (No. RR-6) http://www.cdc.gov/MMWR/PDF/rr/rr4906.pdf
a) Update: Adverse Event Data and Revised American Thoracic Society/CDC
Recommendations Against the Use of Rifampin and Pyrazinamide for Treatment
of Latent Tuberculosis Infection - MMWR 2003; 52 (No. 31)
http://www.cdc.gov/MMWR/PDF/wk/mm5231.pdf
8) HIV-Related TB Treatment
a) Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis –
CDC. December 2007. http://www.cdc.gov/tb/TB_HIV_Drugs/PDF/tbhiv.pdf
b) Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and
Adolescents. (For TB/HIV co-infection treatment, see pages 52-54 and related tables on
pages 87-96). Panel on Antiretroviral Guidelines for Adult and Adolescents. U.S.
Department of Health and Human Services. January 29, 2008.
http://aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL.pdf
The U.S. Department of Health and Human Services (HHS) issues guidelines and
documents for the medical management of HIV infection and issues surrounding HIV
infection. The guidelines documents are periodically reviewed and updated by panels of
HIV experts and can be accessed at http://www.aidsinfo.nih.gov/guidelines
9) Diagnostic Standards/Classification of TB in Adults and Children. American Journal of
Respiratory and Critical Care Medicine 2000; 161.
http://www.cdc.gov/tb/pubs/PDF/1376.pdf
a) Updated Guidelines for the Use of Nucleic Acid Amplification Tests in the
Diagnosis of Tuberculosis. MMWR 2009;58:7-10.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5801a3.htm?s_cid=mm5801a3_e
10) Pediatric Tuberculosis Collaborative Group. Targeted Tuberculin Skin Testing and
Treatment of Latent Tuberculosis Infection in Children and Adolescents. Pediatrics 2004;
114: 1175-1201 http://pediatrics.aappublications.org/cgi/reprint/114/4/S2/1175
11) An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of
Nontuberculous Mycobacterial Diseases. American Journal of Respiratory and Critical Care
Medicine 2007; 175:367-416
http://www.thoracic.org/sections/publications/statements/pages/mtpi/nontuberculousmycobacterial-diseases.html
12) Prevention and Control of Tuberculosis in Correctional and Detention Facilities:
Recommendations from CDC. MMWR 2006;55(No. RR-9): 1-61.
http://www.cdc.gov/mmwr/pdf/rr/rr5509.pdf
13) Extensively Drug-Resistant Tuberculosis (XDR-TB)
a. Emergence of Mycobacterium tuberculosis with Extensive Resistance to SecondLine Drugs - Worldwide, 2000-2004 - MMWR 2006;55:301-305
http://www.cdc.gov/mmwr/PDF/wk/mm5511.pdf
b. Notice to Readers: Revised Definition of Extensively Drug-Resistant
Tuberculosis - MMWR 2006;55:1176
http://www.cdc.gov/mmwr/PDF/wk/mm5543.pdf
c. Extensively Drug Resistant Tuberculosis (XDR TB) - Update from CDC/DTBE
10-20-06 http://www.cdc.gov/tb/xdrtb/update.htm
d. Report of the meeting of the WHO Global Task Force on XDR-TB, Geneva,
Switzerland, October 9-10, 2006
http://www.who.int/tb/xdr/taskforcereport_oct06.pdf
e. Extensively Drug-Resistant Tuberculosis – United States, 1993-2006 – MMWR
2007; 56:250-253 (No. 11)
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5611a3.htm
f. Interim Laboratory Biosafety Guidance for Extensively Drug-Resistant (XDR)
Mycobacterium tuberculosis strains (March 26, 2007)
http://www.cdc.gov/tb/XDRTB/BiosafetyGuidance_xdrtb.htm
g. Algorithms for the Management of Contacts Exposed to a Case of XDR TB
CDC, Division of TB Elimination. Email correspondence June 2, 2007.
http://www.umdnj.edu/globaltb/downloads/medconsultation/Algorithm for Contacts
to XDR TB.pdf
h. XDR TB Contact Investigation Form CDC, Division of TB Elimination
http://www.cdc.gov/tb/XDRTB/TBContactInvestigationForm_.pdf
i. Plan to Combat XDR TB – MMWR 2009;58(No RR3):1-43
http://www.cdc.gov/mmwr/PDF/rr/rr5803.pdf
Other Resources
1) Treatment Pocket Cards New Jersey Medical School Global Tuberculosis Institute
a) Treatment of Tuberculosis: Standard Therapy for Active Disease in Adults and
Adolescents (2007)
http://www.umdnj.edu/globaltb/products/drugcardforadults.htm
b) Treatment of Tuberculosis (TB) in Adult and Adolescent Patients Co-Infected
with the Human Immunodeficiency Virus (HIV) (2007)
http://www.umdnj.edu/globaltb/products/hivpocketcard.htm
c) Treatment of Tuberculosis: Standard Therapy for Active Disease in Children
(2007) http://www.umdnj.edu/globaltb/products/drugcardforchildren.htm
2) Francis J. Curry National Tuberculosis Center and California Department of Health Services,
2008: Drug-Resistant Tuberculosis: A Survival Guide for Clinicians, 2nd edition
http://www.nationaltbcenter.edu/drtb/
3) Francis J. Curry National Tuberculosis Center: Radiographic Manifestations of
Tuberculosis: A Primer for Clinicians, Second Edition
http://www.nationaltbcenter.edu/products/product_details.cfm?productID=EDP-04
4) Treatment Guidelines from the Medical Letter: Drugs for Tuberculosis. 2007;5(55)1522.
http://www.umdnj.edu/globaltb/downloads/medconsultation/TB Treatment Guidelines - The
Medical Letter 2007.pdf
5) Tuberculosis and Air Travel – Guidelines for Prevention and Control, Third Edition –
World Health Organization (2008)
http://www.who.int/tb/publications/2008/WHO_HTM_TB_2008.399_eng.pdf
6) TB-Related News and Journal Items Weekly Update: Provided by the CDC as a public
service, subscribers receive:
• A weekly update of TB-related news items
• Citations and abstracts to new scientific TB journal articles
• TB conference announcements
• TB job announcements
To subscribe to this service, visit: http://www.cdcnpin.org/scripts/listserv/tb_update.asp
7) TB Fact Sheets
Developed by CDC, these 2-page fact sheets provide health care providers with summary
information and references related to current recommendations in the diagnosis, treatment, and
management of TB. These can be accessed at http://www.cdc.gov/tb/pubs/TBfactsheets.htm
Listing of Core TB Resources with Outside Links 02-20-09