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By Massimo Pigliucci A concept road map to understand evolution-creation Evolution IS Change in gene frequencies DOES NOT REQUIRE Intelligent Design IS Descent with modification IS NOT Origin of life IS NOT Origin of the universe 1- Evolution as a change in gene frequencies • Theory from population genetics • Empirical evidence from molecular biology • Examples: viruses, bacteria, plants, fungi, animals (including humans) Example: the HIV virus • Causes a disease of the immune system • Common among vertebrates Two major kinds of human HIV HIV-1 evolved from a chimp virus and attacked human populations in the 1940s in West Africa and in the 1970s in Europe Why is AIDS so difficult to cure? genes (mutations) environment (sexual behavior) 2 – Evolution as descent with modification • Studied by comparative anatomy, paleontology • Evidence from extant organisms’ morphology, physiology, and development • Evidence from the fossil record Example: the evolution of whales Mesonychids Whales (modern & ancient) Artiodactyls (hippos, pigs, camels, sheep) 55 MYA: in the beginning were the early Artiodactyls • Scavengers • Fish hunters bears A sleuth of intermediate forms • 53 MYA: Hymalaiacetus, lived in fresh water and sea • 50 MYA: Pakicetus, lived on both land and water • 45-50 MYA: Ambulocetus, reduced limbs sea lions Ambulocetus Almost like a whale Basilosaurus & co.: Extremely reduced limbs by 35-40 million years ago Modern whales and hippos • Most common recent ancestor: 55 MYA (DNA) • Swim before walking • Nurse young underwater •Testicles remain inside body • Hairless • No sweat 3 – Evolution is NOT a theory of the origin of life Evolution requires heritable variation for selection to act The origin of life is a problem at the interface between physical chemistry and biology What could solve the problem of the origin of life? Complexity theory and the concept of self-organization 4 – Evolution is NOT a theory of the origin of the universe The universe “evolves” only in the general sense of change through time. No selection, no mutation. “Building blocks” of galaxies seen from Hubble How could then the universe have originated? general relativity quantum mechanics superstrings Does evolution fail if it cannot answer “origin” questions? 5 – Does an understanding of the variety of life on earth require ID? Logical objections: 1 - Occam’s razor and avoidance of unnecessary hypotheses David Hume (1779) 2 - Hume’s dictum on extraordinary claims and evidence The burden of proof is on the other side • The story of life on earth appears idiosyncratic, indicating contingency and necessity (e.g. extinction of dinosaurs) • Organisms are not well designed to fit their environment (evolution as bricoleur: human eye) Can you really deny the evidence? chimpanzee spider monkey Homo abilis Homo erectus Homo sapiens A. afarensis