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Opiate Use and Misuse in Oregon – Efforts from a Healthcare for the Homeless Clinic Rachel Solotaroff, MD, MCR Medical Director, Central City Concern May 2, 2013 Objectives Brief introduction of the opiate crisis in our community and in our clinic Our process as a clinic and a community in understanding and addressing this crisis Lessons learned Disclosures No financial relationships to disclose I am a clinician and colleague; not an expert I am an incrementalist; not a trailblazer BACKGROUND Central City Concern CCC’s Mission: “To provide comprehensive solutions to ending homelessness and achieving self-sufficiency” Continuum of integrated services: Affordable housing Addictions treatment Mental health services Recovery support Employment services Primary care Old Town Clinic Integrated into CCC in 2001 Healthcare for the Homeless Clinic 3500 patients; 15,000 PCP visits 35 percent uninsured 99 percent at 100% FPL or below 60-80 percent homeless High prevalence of addiction & mental health disorders Internal medicine; integrated BH, Pharmacy & OT Strong complementary medicine department (ND, Acup) Social medicine curriculum with OHSU Dept. of Medicine Other robust academic partnerships (Pharm, PMHNP, OT) OPIATE USE AND ABUSE IN OREGON – WHERE WE STOOD IN 2008 Deaths due to Drug Poisoning in Oregon Drug poisoning mortality: rate and frequency by year and select drug type, Oregon, 1999-2008 Oregon Public Health Division- Injury Prevention Program 450 12.0 11.0 400 Number of heroin deaths 350 Number of prescription opioid deaths 10.0 9.0 Rate of drug poisoning 300 8.0 7.0 250 6.0 200 5.0 150 4.0 3.0 100 2.0 50 Crude mortality rate per 100,000 Number of drug-related poisonings Number of cocaine deaths 1.0 0 0.0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 *2008 mortality data are preliminary; drug death categories are not necessarily mutually exclusive- deaths may involve multiple drugs. Includes unintentional and undetermined drug poisonings. Data source: Oregon Center for Health Statistics mortality data file. Oregon Health Authority, Office of Disease Prevention and Epidemiology Hospitalizations Unintentional poisoning hospitalization- rate and frequency by drug category and year, Oregon 1997-2007 Oregon Public Health Division- Injury Prevention Program Other drugs (44 categories combined) 35 Opioid analgesics (+ methadone) 1200 Rate of unintentional poisoning 30 1000 25 800 20 600 15 400 10 200 5 0 0 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 Data source: Oregon Hospital Discharge Index Oregon Health Authority, Office of Disease Prevention and Epidemiology Crude hospitalization rate per 100,000 Number of drug-related poisonings 1400 Who’s At Risk? Age distribution of prescription opioid deaths, Oregon, 1999-2009 Oregon Public Health Division- Injury Prevention Program 40 33.1 35 Percent 30 26.5 25 18.7 20 15 10.98 8.66 10 5 0.9 0 Oregon Health Authority, Office of Disease Prevention and Epidemiology 1.46 0.51 The Role of Methadone Drug poisoning mortality: the role of methadone, Oregon, 1999-2008 500 450 400 350 Oregon Injury Prevention Program Public Health Division Supportive Housing Count 300 250 200 150 100 50 0 1999 2000 2001 2002 2008 data are preliminary. Categories are not mutually exclusive- many deaths sumultaneously involve several types of drugs. Includes only deaths with an X40-X44 & Y10Y14 ICD-10 code for underlying cause of death (unintentional and undetermined intent). 2003 2004 2005 2006 2007 2008 All drug and medication-related deaths combined All prescription opioid-related deaths combined Methadone-related deaths Methadone: Grams Sold and Death Rate. Grams methadone sold per 100,000 persons 6000 4.5 4 Grams sold/100,000 population 5000 3.5 Methadone death rate 4000 3 2.5 3000 2 2000 1.5 1 1000 0.5 Oregon Public Health Division- Injury Prevention Program 0 0 1999 2000 2001 2002 2003 2004 2005 2006 Rate of methadone-associated poisoning deaths per 100,000 persons Retail distribution of methadone in Oregon and poisoning mortality rate asociated with methadone in Oregon, 1999-2006 Note: grams sold on left axis, death rate on right axis Sources: US Dept. of Justice, Drug Enf orcement Administration, Of f ice of Diversion Control, Automation of Reports and Consolidated Orders System (ARCOS); Oregon Center f or Health Statistics mortality data f iles. Includes unintetnional and undetermined intent deaths. Factors Among Methadone Decedents 41% prescribed methadone; 30% no Rx Prescriptions: 43% pain; 26% methadone maintenance In 77%, abuse contributed to death 75% history of substance abuse 21% history of substance abuse treatment 52% history of mental illness Sample N=56 Oregon Health Authority, Office of Disease Prevention and Epidemiology Pain Medication Misuse 2008: Oregon is 5th highest state for nonmedical use of prescription painkillers* 6.6% of persons >12 years 8.2% of persons 12-17 years 17.9% of persons 18-25 years – highest in any US state 2013: Oregon is THE highest state for nonmedical use of prescription pain relievers: – 6.4% of all persons >12 years – 7.4% of persons 12-17 years – 15% of persons 18-25 years SAMHSA- 2008, 2013 National Survey on Drug Use and Health, state level data Summary 53% of drug overdoses in Oregon associated with prescription opioids – Overall: 540% increase in since 1999 – Methadone: 1,500% increase in deaths since 1999 – 33% of all drug-related deaths (licit and illicit) associated with methadone Oregon Health Authority, Office of Disease Prevention and Epidemiology ADDRESSING THE EPIDEMIC Back at Home… Providers: - Aware of lack of evidence and risks of opiates - Trying to grapple with patient expectation that “ a pill will make me pain free” - Lack of patient engagement with alternative modalities for pain management - Clinic sessions clogged with patients needing refills - Calls from the Medical Examiner when a death occurred Staff - Struggling with phone calls and walkins for refills - Managing behavioral issues when refills not granted as expected Step 1: Establish Uniform Oversight and Prescribing Guidelines Controlled Substances Review Committee: • Reviews all episodes of serious misuse or misconduct • Reviews all requested new starts on chronic opiate therapy • Provides guidance for complex pain management cases Early prescribing guidelines: • When to refer to CSRC • Prescribing to patient on methadone maintenance, in A&D treatment • Process for new opiate starts • Other contra-indicated substances Chelminski et al. BMC Health Services Research 2005, 5:3 Step 2: Integration of non-pharmacologic pain management and addiction • Occupational Therapy/Group Visits • Naturopathic Medicine/Acupuncture • Education series for providers: • • • Trigger Point Injections Musculoskeletal Exam Physiatry 101 • Integrated Chronic Pain and Addictions Program – “Hot Sauce”: • • • Led by CADC 12-week curriculum Focus on triggers, relapse prevention, alternative pain management Patient, Staff and Provider Response Providers: – Relieved at no longer having to “go at it alone”; “makes being strict less personal”; “enables discussions around public health concerns” – Appreciative that we were no longer a “juice bar”; still feel patients need to embrace acceptance of their responsibility in pain management – Unclear of “net benefit”of Hot Sauce program Staff: – Perceived decreased burden of phone calls and walk-ins Patients: – Some felt groups were supportive and helpful; others felt they were a waste of time – Empathy with providers over having to “answer to some committee” Step 3: Community-Wide Approach Death of Sam Barlow High School senior last December ruled an overdose 13-year-old Medford boy may have died from prescription drug overdose, police say Multnomah County Health Department Guidelines 2011: – Instituted dosage ceiling limit on chronic opiate therapy – Established absolute contra-indications to COT – Established conditions for which chronic opiates could not be prescribed – Community Response: Get on the train, or get run over by the train Oregon Prescription Drug Monitoring Program, 2011 Our Current Controlled Substances Policy ABSOLUTE CONTRAINDICATIONS: • • • • • Any history of diversion No functional improvement No complete workup for pain diagnosis Active substance abuse No non-pharmacological modalities tried, or unwillingness to try them • Greater than 120mg daily of morphine equivalents (40mg methadone) • Use of marijuana (licit or illicit) Our Current Controlled Substances Policy RELATIVE CONTRAINDICATIONS (moving toward absolute*): • • • • • • High opiate risk score No BH screening or undertreated BH condition History of suicide attempt Currently on methadone maintenance History of misuse/overuse Concurrent use of benzodiazepines *While we have made judicious exceptions in these areas, evidence and clinical experience are showing poor results Chronic Pain Recovery Pyramid Strengthening Our Systems and Supports High addiction risk: • • • Brief relapse Early Recovery Minimal support Level Three Hot Sauce Weekly Graduation Criteria: -- Level 3: completion of Hot Sauce -- Level 2: Progress toward goals Engaged in Behavioral health (if nec) Reduction in opiate dosage Acupuncture Low addiction risk BUT: • • • Low self-management Low social supports Low function/activity Level Two RENEW Monthly Group Visits with OT/PCP Behavioral Health Assessment or Impact Monthly “Activity Groups” Low addiction risk: • • • Good self-management Good support Good function/activity Level One Primary Care Only q 2-3 mo visits Risk Management -- UDS – q 3 months -- pill count – q 6 months -- ADR’s – q 3 months -- PDMP: annually Chronic Pain Recovery Program Road Map 4 weeks Income & Employment CP Identified at Volunteering, Intake: Training, Jobs -- ROI’s -- CP acknowledgemt PCP Appt #1 H&P, Record Review, UDS, OPDMP query PCP Appt #2 OT Assess -- BH Screen: CSRC Reviews Data and recommends: • ORT -- No Controlled Substances + Care Plan Recs -- OR -- • PHQ • GAD-7 If + BH Screen • PTSD Screen -- Controlled Substances + Level of Care + Care Plan Recs: • Hot Sauce (Level 3) Behavioral Health • RENEW Provider Groups (Level 2) • Primary Care Only (Level 1) • Other recs such as BH, medication regiment, monitoring guidelines, etc. LESSONS LEARNED Lessons Learned Absolute necessity and benefit of guidelines and review committee to which we all adhere “Cognitive dissonance” between population level data and the patient sitting in front of you While it’s great to have so many wellness resources, patient still needs to be engaged and receptive Addictions/Chronic Pain program such as “Hot Sauce” is innovative, but integration of suboxone has been the game-changer Need better focus on/understanding of intersection of trauma, addictions and chronic pain THANK YOU!