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Pharmacology and Toxicology: Introduction
Faculty Affiliation
Medicine
Degree Programs
Pharmacology
MSc
PhD
Field:
Applied Clinical Pharmacology
Combined Degree Programs
MD / PhD
Collaborative Programs
The following collaborative programs are available to students in participating degree programs
as listed below:
1. Addiction Studies
o Pharmacology, MSc, PhD
2. Biomedical Toxicology
o Pharmacology, MSc, PhD
3. Cardiovascular Sciences
o Pharmacology, MSc, PhD
4. Human Development
o Pharmacology, PhD
5. Neuroscience
o Pharmacology, MSc, PhD
6. Resuscitation Sciences
o Pharmacology, MSc, PhD
7. Women's Health
o Pharmacology, MSc, PhD
Overview
The Department of Pharmacology and Toxicology offers graduate programs leading to the
degrees of Master of Science and Doctor of Philosophy in Pharmacology. Faculty conduct
research in the following areas:
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biochemical and molecular pharmacology
cardiovascular pharmacology
clinical pharmacology
drug addiction
drug metabolism, distribution, and pharmacokinetics
endocrine pharmacology
immunopharmacology
neuropharmacology
pharmacogenetics
psychopharmacology
receptor pharmacology
second messengers and signal transduction
toxicology
All MSc and PhD students are expected to undertake self-directed study and to demonstrate
proficiency in pharmacological principles throughout the course of their graduate program.
Contact and Address
Web: www.pharmtox.utoronto.ca
Email: [email protected]
Telephone: (416) 978-5244
Fax: (416) 978-6395
Department of Pharmacology and Toxicology
University of Toronto
Room 4207, Medical Sciences Building
Toronto, Ontario M5S 1A8
Canada
Pharmacology and Toxicology: Pharmacology MSc
Master of Science
Minimum Admission Requirements
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Applicants are admitted under the General Regulations of the School of Graduate
Studies. Applicants must also satisfy the Department of Pharmacology and
Toxicology's additional admission requirements stated below.
Appropriate bachelor's degree from a recognized university with a final-year average of
at least a B+.
Applicants are normally required to have taken courses in physiology, biochemistry, or
applied sciences sufficient to form a foundation for their work in pharmacology.
All successful applicants are responsible for obtaining research supervision and
financial support before they are permitted to officially register in their program.
Program Requirements
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Minimum period of one full year of residence, during which time the student is required
to be on campus full-time and consequently in such geographical proximity as to be
able to participate fully in the department's activities associated with the program.
PCL 1002Y Graduate Pharmacology. The academic program may require additional
coursework.
Each student will present a departmental seminar after approximately one year in the
program.
Each student will participate in a research program and present the results of the
investigation as a written thesis. The thesis will be evaluated and defended to the
satisfaction of a thesis examination committee.
MSc students in pharmacology who intend to continue their studies in the PhD program
may choose to be evaluated during their MSc oral defence.
Pharmacology and Toxicology: Pharmacology MSc, Applied
Clinical Pharmacology Field
Minimum Admission Requirements
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Applicants are admitted under the General Regulations of the School of Graduate
Studies. Applicants must also satisfy the Department of Pharmacology and
Toxicology’s additional admission requirements stated below.
An appropriate bachelor’s degree from a recognized university with a final-year average
of at least a B+.
Applicants are normally required to have taken courses in physiology, biochemistry, or
applied sciences sufficient to form a foundation for their work in pharmacology.
Advanced-Standing Option
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At the discretion of the program director, applicants may be considered for advanced
standing with either:
o a bachelor’s degree in pharmacology or biomedical toxicology or
o MD degree (undergraduate medical education) with coursework in
pharmacology.
Program Requirements
Completion of 8.0 full-course equivalents (FCEs) as follows:
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Year 1 (3.5 FCEs total):
o PCL 1001Y Systems Pharmacology
o PCL 1004Y Clinical Pharmacology
o PCL 1402H Pharmacology and Toxicology in Drug Development
o PCL 1491H Clinical Pharmacology: Principles in Practice
o PCL 1100H Applied Skills in Clinical Pharmacology
Year 2 (3.5 FCEs total):
o Required courses (1.5 FCEs):
 PCL 1002Y Graduate Pharmacology
 PCL 1101H Technology, Techniques, and Translation in Pharmacology
and Toxicology
Plus
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Elective courses (2.0 FCEs) from the following list:
 PCL 1012H Cognitive Neuropharmacology
 PCL 1300H Selected Topics in Clinical Studies
 PCL 2100H Practicum in Clinical Pharmacology
 PCL 2101Y Practicum in Clinical Pharmacology
 BTC 1830H Medical and Scientific Challenges in Marketing New
Therapeutics
 JFK 1120H Selected Topics in Drug Development I
 JNP 1014Y Interdisciplinary Toxicology
 JPM 1005Y Behavioural Pharmacology
 LMP 1407H Introductory Biostatistics and Clinical Investigation or
CHL 5201H Biostatistics for Epidemiologists
Clinical practicums (either PCL 2100H or PCL 2101Y; CR/NCR), if chosen from
electives, must be completed by Year 2.
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Major Research Project (1.0 FCE).
Students will enrol in PCL 2200Y0, normally in the Summer of Year 1 or no later than
the Fall of Year 2.
Advanced-Standing Option
Completion of at least 4.0 FCEs including:
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PCL 1002Y Graduate Pharmacology
PCL 1004Y Clinical Pharmacology
PCL 1100H Applied Skills in Clinical Pharmacology
At least one half-course elective (0.5 FCE) chosen from the elective list above, and
upon recommendation of the program director.
PCL 2200Y0 Major Research Project, taken in the Fall of Year 1.
Program Length
6 sessions full-time (typical registration sequence: F/W/S/F/W/S);
3 sessions advanced-standing (typical registration sequence: F/W/S);
9 sessions part-time
Time Limit
3 years full-time;
6 years part-time
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Course that may continue over a program. The course is graded when completed.
Pharmacology and Toxicology: Pharmacology PhD
Doctor of Philosophy
Minimum Admission Requirements
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Applicants are admitted under the General Regulations of the School of Graduate
Studies. Applicants must also satisfy the Department of Pharmacology and
Toxicology's additional admission requirements stated below.
Appropriate master's degree from a recognized university with an average of at least a
B+ in master's degree courses.
Applicants are normally required to have taken courses in physiology, biochemistry, or
applied sciences sufficient to form a foundation for their work in pharmacology.
The department determines the eligibility of prospective students. The department
assesses the student's ability for advanced study and independent research in
pharmacology.
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Well-qualified students with excellent research potential holding an appropriate
bachelor's degree from a recognized university may be considered for direct admission
to the PhD program. These applicants must have achieved a minimum final year
average of A-.
Applicants admitted without prior screening (i.e., with MSc degrees from other
departments or universities, and students admitted with a bachelor's degree) will have
their research ability reviewed after completion of one year. Upon successful
completion of a departmental seminar and recommendation from the student's advisory
committee, the student will be permitted to proceed with the PhD program.
Students transferring from the master's program in pharmacology to the PhD program
may receive full credit for master's courses towards doctoral course requirements, with
the department's permission.
The department must be satisfied about the applicant's background, accomplishments,
and financial support.
All successful applicants are responsible for obtaining research supervision and
financial support before they are permitted to officially register in their program.
Program Requirements
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Minimum period of two full years of residence, during which time the student is
required to be on campus full-time and consequently in such geographical proximity as
to be able to participate fully in the department's activities associated with the program.
PCL 1002Y Graduate Pharmacology (major subject), PCL 1003Y0 Seminars in
Pharmacology (Credit/No Credit course), 1.0 additional FCE (minor subject), and any
other courses advised by the Graduate Education Committee. The student's advisory
committee should help the student determine the minor course.
Pharmacology graduate faculty members also offer a variety of laboratory-based and
tutorial-based learning modules to provide breadth to the student's training experience
beyond their particular areas of research focus. During their program, PhD students are
required to choose four breadth modules from among available options. 0.5 FCE from
outside the student's research area may substitute for one of the five breadth modules.
The student's advisory committee will assist the student in choosing suitable modules.
As part of the course requirement for PCL 1003Y0 Seminars in Pharmacology, the
student must present thesis material in seminars to the department on two occasions,
one of which will take place between two and six months prior to the departmental
Final Oral Examination.
Each student will participate in a research program and present the results of the
investigation as a written thesis. The thesis must be orally defended to the satisfaction
of a thesis examination committee.
PhD students in other departments who desire to take a minor in pharmacology will be
permitted to take one of the listed courses depending on their previous training and
space availability in the course.
Program Length
4 years full-time; 5 years direct-entry
Time Limit
6 years full-time; 7 years direct-entry
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Course that may continue over a program. The course is graded when completed.
Pharmacology and Toxicology: Pharmacology MSc, MSc
Applied Clinical Pharmacology Field, PhD Courses
The department should be consulted each session as to course offerings. Students may also find
up-to-date course information on the departmental website.
PCL 1001Y
PCL 1002Y
PCL 1003Y0
PCL 1004Y
PCL 1012H
PCL 1101H
PCL 1110H
PCL 1300H
PCL 1402H
PCL 1491Y
PCL 2101H0
PCL 2102H0
PCL 2200Y0
PCL 2201Y0
JFK 1120H
JFK 1121H
JFK 1122H
JNP 1014Y
JNP 1016H
Systems Pharmacology
Graduate Pharmacology
Seminars in Pharmacology (Credit/No Credit)
Clinical Pharmacology
Cognitive Neuropharmacology
Technology, Techniques, and Translation in Pharmacology and Toxicology
Applied Skills in Clinical Pharmacology
Selected Topics in Clinical Pharmacology and Toxicology (Credit/No
Credit) (prerequisite: PCL 1100H)
Pharmacology and Toxicology in Drug Development
Clinical Pharmacology: Principles in Practice (co-requisite: PCL 1004Y or
prior pharmacokinetics course)
Practicum in Clinical Pharmacology I (Credit/No Credit) (prerequisite: PCL
1100H)
Practicum in Clinical Pharmacology II (Credit/No Credit) (prerequisite:
PCL 1100H)
Major Research Project (prerequisite or co-requisite: PCL 1100H)
Research Project Extended Study (Credit/No Credit) (prerequisite: PCL
2200Y)
Selected Topics in Drug Development I
Selected Topics in Drug Development II
Drug Transport Across Biological Membranes
Interdisciplinary Toxicology
Graduate Seminar in Toxicology
JNP 1017H+
JNP 1018H+
JNR 1444Y
JPM 1005Y
JYG 1555H
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Current Topics in Molecular and Biochemical Toxicology
Molecular and Biochemical Basis of Toxicology
Fundamentals of Neuroscience: Cellular and Molecular
Behavioural Pharmacology
Advanced Topics: Cellular and Molecular Neurobiology
Course that may continue over a program. The course is graded when completed.
Extended course. For academic reasons, coursework is extended into session following
academic session in which course is offered.