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Circulatory System in Animals Regents Biology 2006-2007 Feeding the Need for Energy Supplies in fuel (sugars) digestive system oxygen respiratory system Waste out CO2 respiratory system Need to pick up & deliver the supplies & wastes around the body circulatory system Regents Biology Circulatory system Made up of 3 parts organ heart tissues & cells blood red blood cells blood vessels (vascular system) arteries veins capillaries Regents Biology Circulatory systems All animals have: muscular pump = heart tubes = blood vessels circulatory fluid = “blood” open hemolymph Regents Biology closed blood Vertebrate circulatory system 2 part system SL AV AV lungs artery to lungs vein from lungs to heart heart vein from body to heart body Regents Biology artery to body Circulation of Blood in Mammals Circulation 2 part system to lungs Circulation to lungs lungs blood gets O2 from lungs brings O2-rich blood back to heart Circulation to body heart pumps O2-rich blood to body picks up nutrients from digestive system brings CO2 & cell wastes from body to heart Regents Biology body Circulation to body Stops along the way… Lungs pick up O2 / clean out CO2 Small Intestines pick up nutrients from digested food Large Intestines pick up water from digested food Liver clean out worn out blood cells Regents Biology More stops along the way… Kidneys filters out wastes (urea) excess salts, sugars & water Bone picks up new red blood cells Spleen picks up new white blood cells Regents Biology Mammalian Heart 4-Chambered heart atria (atrium) thin wall collection chamber left atrium receive blood ventricles thick wall pump right pump blood out atrium Regents Biology right ventricle left ventricle Heart valves 4 valves in the heart flaps of connective tissue prevent backflow SL AV valve between atrium & ventricle keeps blood from flowing back into atrium when ventricle pumps “lub” AV AV Semilunar valves between ventricle & arteries prevent backflow from arteries into ventricles “dub” Regents Biology Heart murmur leaking valve causes hissing sound blood squirts backward through valve Electrical signals allows atria to empty completely before ventricles contract stimulates ventricles to contract from bottom to top, driving blood into arteries heart pumping controlled by electrical impulses Biology Regents signal also transmitted to skin = EKG Measurement of blood pressure High Blood Pressure (hypertension) if top number (pumping) > 150 if bottom number (filling) > 90 Regents Biology Blood vessels arteries veins artery venules arterioles arterioles capillaries venules veins Regents Biology Arteries: Built for their job Arteries blood flows away from heart thicker walls provide strength for high pressure pumping of blood elastic & stretchable maintains blood pressure even when heart relaxes Regents Biology Major arteries aorta carotid = to head to brain & left arm to right arm to body pulmonary artery pulmonary coronary artery = arteries to lungs Regents Biology Coronary arteries bypass surgery Regents Biology Veins: Built for their job Veins Blood flows toward heart blood returns back to heartOpen valve thinner-walled blood travels back to heart at low speed & pressure blood flows because muscles contract when we move squeeze blood through veins Closed valve valves in large veins in larger veins one-way valves allow blood to flow only toward heart Regents Biology Major Veins superior vena cava = from upper body pulmonary vein = from lung inferior Regentsvena Biology cava = from lower body pulmonary vein = from lung Capillary: Where all the action is Capillaries very thin walls allows exchange of materials across capillary O2, CO2, H2O, food, waste diffusion Regents Biology Blood & blood cells Blood is a tissue of fluid & cells plasma fluid dissolved salts, sugars, proteins, and more cells red blood cells (RBC) transport O2 in hemoglobin white blood cells (WBC) defense & immunity platelets blood clotting Regents Biology Blood Cell production ribs, vertebrae, breastbone & pelvis Stem cells “parent” cells in bone marrow mature into many different types of cells white blood cells white blood cells red blood cells Regents Biology Red blood cells Small round cells produced in bone marrow lose nucleus & mitochondria more space for hemoglobin iron-containing protein that transports O2 last 3-4 months (120 days) filtered out by liver ~3 million RBC destroyed 5-6 million RBC in each second tiny drop of human replaced by 3 million more blood produced each second 5 liters of blood in Regents Biology body Hemoglobin Protein which carries O2 O2 O2 Regents Biology emergency repair of circulatory system Blood clotting chemical emergency signals Regents Biology platelets seal the hole fibrin protein fibers build clot Cardiovascular disease Atherosclerosis & Arteriosclerosis deposits inside arteries (plaques) develop in inner wall of the arteries, narrowing their channel increase blood pressure increase risk of heart attack, stroke, kidney damage normal artery Regents Biology hardening of arteries Cardiovascular health Genetic effects Diet diet rich in animal fat increases risk of CV disease Exercise & lifestyle smoking & lack of exercise increases risk of CV disease Regents Biology bypass surgery Cardiovascular health (U.S. 2001) Heart Disease 696,947 Cancer 557,271 Stroke 162,672 Chronic lower respiratory diseases 124,816 Accidents (unintentional injuries) 106,742 Diabetes 73,249 Influenza/Pneumonia 65,681 Alzheimer's disease 58,866 Nephritis, nephrotic syndrome & nephrosis 40,974 Septicemia 33,865 Regents Biology Heart Disease Heart disease death rates 1996-2002 Adults ages 35 and older Regents Biology Women & Heart Disease Death rates for heart disease per 100,000 women, 2002 Risk factors Smoking Lack of exercise High fat diet Overweight Heart disease is 3rd leading cause of death among women aged 25–44 years & 2nd leading cause of death among women aged 45–64 years. Regents Biology Any Questions?? Regents Biology 2006-2007