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Product Information Sheet – October 2014 Pancreatic Enzyme Formula What Is It? What Is The Source? Pancreatic Enzyme Formula provides natural enzymes to nutritionally support proper digestive function. This formula is now offered in acid-resistant capsules with pH targeted release for maximal enzyme delivery to the small intestine.* Pancreatin is a full-strength, undiluted porcine extract, containing digestive enzymes lipase, protease and amylase in their natural ranges. Gellan gum is derived from Pseudomonas elodea. Uses For Pancreatic Enzyme Formula Recommendations Pure Encapsulations recommends 1–2 capsules with each meal. Digestion Support: Pancreatic Enzyme Formula is designed to aid the body’s natural digestive process. It provides a highly concentrated form of enzymes naturally secreted by the pancreas, which are essential to the digestion of food and absorption of nutrients. The formula contains lipase, which digests fat; proteases, which digest protein; and amylases, which digest starch.* Are There Any Potential Side Effects Or Precautions? At this time, there are no known side effects or precautions. If pregnant or lactating, consult your physician before taking this product. Special Features Are There Any Potential Drug Interactions? Pancreatic Enzyme Formula is offered in acid-resistant capsules with pH targeted release. These capsules are designed to resist disintegration in an acidic environment (i.e. stomach) and dissolve in more alkaline environments (i.e. small and large intestine). This technology helps to protect the enzymes from stomach acid. At this time, there are no known adverse reactions when taken in conjunction with medications. Consult your physician for more information. Disintegration in Simulated Gastric and Simulated Intestinal Fluids each vegetarian capsule contains % Ingredient Dissolved 90 80 70 ph 1.2 stage 1–2 capsules with each meal. ph 6.8 stage 50 0 Pancreatin (from porcine) (lactose free)....................................... 500 mg provides: lipase........................................................................ 17,500 USP units protease.............................................................. 110,000 USP units amylase.............................................................. 120,000 USP units other ingredients: vegetarian capsule (cellulose, gellan gum, water) 100 60 Pancreatic Enzyme Formula 40 30 20 10 0 0 30 60 90 120 150 180 210 240 Time (minutes) Percentage of ingredient released in simulated gastric fluids and intestinal fluids.† After two hours in pH 1.2 simlated gastric fluids, less than 20% of capsule contents were released. After 45 minutes in pH 6.8 simulated intestinal fluids, more than 80% of capsule contents had dissolved. This test was performed under a specific protocol which is available upon request. † *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 800-753-2277 | PureEncapsulations.com The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product. Consult your physician for any health problems.