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Overview of Treatment Modalities Jessica M. Cronce, PhD University of Oregon How do gambling problems develop? Social Psycho Bio • • • • • • • BIO: Genetic predisposition Neurochemistry Effect of medications Immune response HPA axis (stress) Flight-fight response Other physiological responses Biology: Neurotransmitters Disordered Gambling: Noraepinephrine = heart rate / excitement Serotonin = impulsive behavior Dopamine = reward seeking behavior (some dopamine agonists have been shown to induce pathological gambling behavior) How do gambling problems develop? Social Psycho Bio • • • • • • PSYCHO: Perceptions Thoughts/cognitions • Attitudes & beliefs Emotions Learning Memory Behavior • Coping Psychology: Cognitions ? ? No matter how much we KNOW that each event is independent, we tend to hold a deep belief that chance is self-correcting in the short run (the Gambler’s Fallacy). Psychology: Learning Withdrawal is a reinforcer How do gambling problems develop? Social Psycho Bio • • • • • • • SOCIAL: Social support Family dynamics Peer relationships Culture Socio-economic status Access to gambling Exposure to events Levels of “Social”: Ecological Model Microsystem: Direct environment e.g., Family, School, Church Mesosystem: Interaction of microsystems e.g., Parents<=>School Exosystem: Indirect Environment e.g., Spouse’s employment Macrosystem: Culture e.g., Economy, social norms Chronosystem: Change over time e.g., Aging, culture change How do gambling problems develop? Social Environment Psycho Bio Genes Gene x Environment interactions (G x E) Gene-Environment Correlations (rGE) Gene-environment interactions (GxE): Environment causes gene expression • The “C gene” in Himalayan rabbits regulates development of pigments in the fur and skin, and is maximally active from 59°F to 77°F and inactive above 95°F. Reared at 68°F Reared at 96°F http://www.nature.com/scitable/topicpage/environmental-influences-on-gene-expression-536 “Genes load the gun; the environment pulls the trigger.” https://www.aeaweb.org/research/has-tribal-gaming-been-a-boon-for-american-indians How do we alleviate gambling problems? BIOLOGY PSYCHOLOGY SOCIOLOGY Medication Motivational Interviewing (MI) Family education/therapy Change biology through psychology (CBT, mindfulness meditation) Cognitive Therapy Cognitive-Behavioral Therapy (CBT) Dialectical Behavior Therapy (DBT) 12-step programs Change cultural norms Limit access to gambling venues (exclusion) Laws Medication Norepinephrine: • Bupropion* (Wellbutrin) Serotonin: • SRIs & SSRIs* • Mood Stablizers* (Lithium carbonate) Dopamine antagonist: • Naltrexone (ReVia)** *FDA approved for MDD **FDA approved for SUDs, which are highly comorbid with disordered gambling 1Foster Some emerging evidence for potential regulating effect of **glutamatergic medications (e.g., acamprosate, Nacetylcysteine).1 Olive, Cleva, Kalivas & Malcolm (2012) Motivational Interviewing (MI) Rooted in: • Carl Rogers; Humanism • Transtheoretical model of change Client-centered form of guiding • vs. following or directing Helps people get “unstuck”, resolving their own ambivalence regarding change David Hodgins: MI + self-help workbook1 = fewer gambling days, less lost money, and lower SOGS scores up to 2 years later2 1BECOMING A WINNER: Defeating Problem Gambling; Adaptation: http://www.oregonpgs.org/workbooks/gear-workbook.pdf 2Hodgins, Currie, el-Guebaly, & Peden (2004) Cognitive Therapy (CT) Rooted in: Cognitivism: behavior Thoughts shape Establishing clear understanding of randomness (i.e., the outcomes of gambling events are independent, thus past events do not signal future outcomes) Increasing awareness of other erroneous beliefs about gambling (e.g., illusions of control, belief in luck/systems) and how they relate to the individual’s gambling behavior Correcting/changing erroneous beliefs with thought records Robert Ladouceur: CT = decreased gambling frequency, urges, and PG symptom severity up to 12 months later1 1Ladouceur, Sylvain, Boutin, Lachance, Doucet, Leblond, & Jacques (2001) Cognitive-Behavioral Therapy (CBT) Rooted in: Behaviorism: Behaviors are shaped by internal (thoughts) and external contingencies Changing thoughts, emotional reactions, or behaviors can “break the chain” leading to problems Focuses on changing unhelpful thoughts and behaviors, or adding helpful thoughts and behaviors Nancy Petry: CBT = reduced gambling severity up to 12 months later1 1Petry, Ammerman, Doersch, Gay, Kadden, Molina, & Steinberg (2006) CBT A B C A: Make a mistake at work. ntecedents B: Think: “I can’t do anything right!” ehaviors/beliefs B: Feel: Sad, Worthless B: (Think: “I need to feel like a winner.” onsequences “I need to do something fun.”) Challenge cognitions Teach adaptive coping B: Go out to the casino and gamble. skills Teach protective behaviors C: Lose my money needed for bills. Dialectical Behavior Therapy (DBT) Rooted in: Behaviorism Acceptance and mindfulness Focuses on accepting emotions without letting emotions dictate behavior, and simultaneously changing other contingencies that reinforce problematic behavior. DBT DBT has been tested in a small pilot study for treatment-resistant gamblers with apparent clinically-significant effects, but these were not statistically significant.1 However, DBT is effective at treating Borderline Personality Disorder (BPD), which may be present in roughly 1 in 8 (13.1%) treatment seeking gamblers.2 As impulsive gambling can be a diagnostic feature of BPD, referring these individuals to DBT treatment may eliminate gambling behaviors. 1Christensen et al. (2013); 2Dowling et al. (2015) Mindfulness Meditation Key component of DBT. Has been added to CBT1 and CT2 with some success, but more research is needed; combining mindfulness with CT/CBT more reliably shown effects on depression (MBCT). Has been shown to be effective for substance use disorders (mindfulness-based relapse prevention; MBRP). May similarly reduce relapse to gambling by decreasing dissociation, avoidance coping, and reactive response to urges. Mindfulness meditation has been shown to alter brain structure and activation in regions related to attention, memory, affect, emotion regulation, and selfawareness,3 as well as positively impact immune functioning.4 1Toneatto, 3Tang, Pillai, & Courtice (2014); 2de Lisle, Dowling, & Sabura Allen (2011); Holzel, & Posner (2015); 4Davidson et al. (2003) Self-Help Programs Gamblers Anonymous (GA) is the most widely available gambling treatment approach. Limited research due to anonymous nature of the program. Used as both primary treatment (self-help) and aftercare (referral to GA following formal treatment). >50% of people attend less than 6 sessions1, and the median number of sessions attended is zero2 GA, like any treatment, doesn’t work for everyone. Consider whether GA as aftercare will work for your client, or if something else is needed. May be less effective for young adults and adolescents to attend general adult GA meetings. SMART Recovery meetings may be an alternative. Develop Moderation Management for gambling? 1Petry (2003); 2Petry & Weiss (2009) Limit gambling access Stimulus control: • Self-exclusion • Procedures and enforcement differ from state to state, venue to venue, gambling modality to gambling modality • Breaches are common • Everi STeP: block access to cash at casino ATMs and booth services • GamBlock: blocks access to online gambling • Advocate for local or state laws to limit gambling access Enlist help of family members (couples/family therapy) Case Study Exercise Please break up into groups of 2-3 people. Read the case study I’ve provided. Work together to answer the questions on the back of the page. We’ll come back together to discuss the case before the end of the session. “Natural recovery” & moderation About 33% of individuals with PG quit or reduce gambling on their own without treatment or GA. Resolved gamblers most frequently report they stopped gambling via “stimulus control” and “new activities.” Maintain changes through “new activities,” “remembering negative consequences,” and “social support.”