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CATALOG OF ANTIBODIES FOR
MARKERS
Stem Cell • Neural • Fibroblast • Organelle • Cancer
For research purposes only.
Not for use in humans.
Prices subject to change.
FAX: 303.730.1966 • WEB: www.novusbio.com
2
Table of Contents
Stem Cell Markers................ 2-5
Marker Antibodies
Stem Cell Marker Antibodies
Hematopoietic Stem Cell .............................. 2-5
Mesenchymal Stem Cell .................................... 2
Embryonic Stem Cell .................................... 2-5
Neuronal Stem Cell .......................................... 3
Neural Markers ..................6-12
Keratinocyte Stem Cell ...................................... 3
Hemangioblast Stem Cell .................................. 5
Fibroblast Marker Antibodies ..................... 6
Neural Cell Marker Antibodies
Organelle Cell Markers .... 12-16
Musashi 1
Astrocyte/Astroglia Markers ............................... 6
General Glial Cell Markers................................ 7
Microglia Markers ............................................. 7
Neuronal Markers...................................... 8-10
Oligodendrocyte Markers .......................... 10-11
Cancer Markers
C
M k ............... 17-22
Schwann Cell Markers.................................... 11
Organelle Cell Marker Antibodies
Autophagic Vesicles Markers........................... 12
Centrosome Markers...................................... 12
Endosome Marker.......................................... 13
GFAP
Endoplasmic Reticulum Markers.............................. 13
Application Key
Golgi Complex .............................................. 14
ELISA - Elisa
Lysosome Markers ......................................... 15
FACS - Fluorescent Activated Cell Sorting
Mitochondrial Markers ............................ 15-16
ICC - Immunocytochemistry
Nuclear Markers ............................................ 16
IF - Immunofluorescence
IHC - Immunohistochemistry
IHC-Fr - Immunohistochemistry Frozen
IHC-P - Immunohistochemistry Paraffin
IP - Immunoprecipitation
RIA - Radioimmunoassay
Cancer Marker Antibodies
Breast Cancer.......................................... 17-19
Colorectal Cancer .................................... 19-20
Lung Cancer ........................................... 20-21
Prostate Cancer .............................................. 22
Beta Tubulin 3
WB - Western Blot
Reactivity Key
Am - Amphibian Ha - Hamster
Av - Avian
Hu - Human
Bb - Baboon
Ma - Mammal
Bv - Bovine
Mk - Monkey
Ca - Canine
Mu - Mouse
Ch - Chicken
Po - Porcine
Dr - Drosophila
Rb - Rabbit
Eq - Equine
Rt - Rat
Fe - Feline
Ye - Yeast
Gp - Guinea Pig Xp - Xenopus
Gt - Goat
1
UCHL1
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Stem Cell Markers
Functionally, stem cells are able to propagate and
generate additional stem cells, and can differentiate
into various progenitor cells which further maturate
along specific lineages. Stem cell markers allow for
the identification and isolation of stem cells in different
types of tissues and cell populations. Such markers
allow identification of embryonic, hematopoietic,
mesenchymal/stromal, and neural stem cells.
Embryonic stem (ES) cells, derived from the inner cell
mass of preimplantation embryos, are recognized as
CD34 Antibody
Hematopoietic Stem Cell Marker
NB600-1071
Staining of murine
hair follicles using
NB600-1071.
Species: Mu
Applications: FACS, IHC, IHC-P, IP, WB
CD34 Antibody
Hematopoietic Stem Cell Marker
NB100-1934
Staining of human
tonsil using
NB100-1934.
Species: Hu, Mk
Applications: IHC, IP, WB
the most pluripotent population, having the greatest
developmental potential. However, for many
applications adult stem cells may be preferred due
to ethical issues involved in the derivation of ES cells.
Stem cell research is poised to allow the development of
new therapies through repair, replacement, and
regeneration of damaged or diseased cells and tissues
making it one of the most exciting frontiers in modern
medicine.
CD133 Antibody
Hematopoietic Stem Cell Marker
NB120-16518
CD117 Antibody
Hematopoietic Stem Cell Marker
NB600-765
CD133 is a cell-surface protein that
identifies neural stem cells, which give
rise to neurons and glial cells. This
antibody is expressed on primitive
hematopoietic stem and progenitor
cells, retinoblastoma, hemangioblasts,
and neural stem cells as well as on
developing epithelia.
CD117 is expressed on the surface
of hematopoietic stem cells as well as
other cell types. This receptor binds
to stem cell factors.
Species: Hu, Mu
Applications: ELISA, ICC, IF, IHC, IHC-P, WB
CD105 Antibody
Mesenchymal Stem Cell Marker
NB600-1011
This 90 kDa disulfide-linked
homodimer is expressed by vascular
endothelial cells. It is suggested that
CD105 functions in adhesion and
embryonic angiogenesis.
Species: Mu
Applications: FACS, IHC-Fr, IP, WB
The highly glycosylated 75-120 kD antigen
CD34 is possibly an adhesion molecule
with a putative role in early hematopoiesis
by mediating the attachment of stem cells
to the bone marrow extracellular matrix or
directly to stromal cells. It could act as a
scaffold for the attachment of lineage
specific glycans, allowing stem cells to
bind to lectins expressed by stromal cells
or other marrow components. Staining for
CD34 has been used to measure
angiogenesis, which reportedly predicts
tumor recurrence.
Species: Hu, Mk
Applications: FACS
ABCG2 Antibody
Hematopoietic Stem Cell Marker
NB100-2177
ABCG2 (ATP-binding cassette
superfamily G member 2) is a
hematopoietic stem cell marker that
is found in a wide variety of stem
cells.
Species: Hu
Applications: ICC, IHC-Fr, IHC-P, WB
CRIPTO Antibody
Embryonic Stem Cell Marker
NB100-1597
Detection of Cripto
in MDA-MB21 lysate
using NB100-1597
CRIPTO Antibody
Embryonic Stem Cell Marker
NB100-1598
Detection of Cripto in
MDA-MB21 lysate
using NB100-1598.
Species: Hu
Applications: WB
Species: Hu
Applications: WB
The cripto gene is expressed both in embryonic stem cells and during the early phases of
embryo development, while, in the adult, it is reactivated in a wide range of epithelial cancers.
Connexin 43 Antibody
NB100-722
Detection of
Connexin 43 in rat
hippocampal lysate
(showing
specifity, lane 1) and
lambda-phosphatase
incubated rat
Species: Hu, Mu,
hippocampal lysate
Mk, Rt
(negative control, lane
Applications: WB
2) using NB100-722.
For research purposes only.
Not for use in humans.
Prices subject to change.
Connexin 43 Antibody
NB300-309
Detection of
Connexin 43 in rat
cerebellar lysate
using NB300-309.
Species: Hu, Mu, Mk, Rt
Applications: WB
Connexin 43 is a negative cell surface
marker for the stem cell-containing
population of human limbal epithelial
cells. Connexin 43 forms gap-junctional
channels and regulates the permeability
of these gap junctions to small organic
molecules. Gap junctional intercellular
communication is thought to play a key
role in development and may also be
involved in epilepsy.
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4
Keratin 19 Antibody
Pancreatic Stem Cell Marker
NB110-56914
Staining of HeLa cells
using NB110-56914.
Musashi-1 Antibody
Neuronal Stem Cell Marker
NB100-1759
Staining of
neural rosettes
using NB100-1759.
PSCA Antibody
Prostate Stem Cell Marker
NB120-15168
Staining of human
breast cancer using
NB120-15168.
Species: Hu
Applications: IHC, ICC, FACS, IP, WB
Species: Hu, Mu, Rt
Applications: ICC, IHC, IHC-P, WB
Musashi-1 is important for cell fate
determination, with a role in maintenance
of the stem cell state, differentiation and
tumorigenesis.
Species: Hu
Applications: IHC-P
NB100-58842
NB100-588
CK19 is synthesized mainly in embryonic
and adult simple epithelia, but has also
been found in stratified epithelia as well.
NANOG Antibodies
Embryonic Stem Cell Markers
Nanog is a molecular marker that
recognizes the undifferentiated state of
stem cells in mouse and human. It is a
divergent homeodomain protein that
directs propagation of undifferentiated
ES cells. Nanog-deficient embryonic
stem cells lose pluripotency and
differentiate into extraembryonic endoderm lineage.
Species: Mu
Applications: IP, WB
Species: Mu
Applications: IHC
NB100-56450
NB110-40414
NB100-59737
Detection of
Nanog in
HeLa nuclear
lysates using
NB100-59737.
Species: Hu
Applications: ELISA, WB
Detection of
Nanog in mouse
embryonic stem cells
using NB100-588.
Staining of mouse
teratoma using
NB100-58846.
Detection of Nanog
in (A) HeLa and (B)
NIH/3T3 cells using
NB100-56450.
Detection of
Nanog in human
hippocampus tissue
lysate using
NB110-40414.
Species: Hu
Applications: WB
Species: Hu, Mu, Mk, Gt
Applications: WB
p63 Antibody
Keratinocyte Stem Cell Marker
NB110-57175
Staining of paraffinembedded human
breast carcinoma
using NB110-57175.
Nestin Antibody
Neuronal Stem Cell Marker
NB300-265
Detection of nestin in
human fetal temporal
lobe tissue lysates
using NB300-265.
Lane 1: 0.5 ug/ml
Lane 2: 2 ug/ml
Nestin Antibody
Neuronal Stem Cell Marker
NB100-1604
Species: Hu, Mu, Rt
Applications: FACS, IHC, WB
Species: Hu
Applications: WB
Species:
Species:
i
Mu
Mu
Applications: ICC, IHC
p63 Antibody
Keratinocyte Stem Cell Marker
NB110-57309
Immunofluorescent
staining of A431 cells
using NB110-57309.
Staining of
neural stem cells of
the ventricular zone
of the CNS using
NB100-1604.
Nestin is a Class VI intermediate filament expressed in the developing CNS in early
embryonic neuroepithelial stem cells. This protein has been widely used as a predominant
marker for stem/progenitor cells, glioma cells, and tumor endothelial cells.
Podocalyxin Antibody
Hematopoietic Stem Cell Marker
NB110-41503
Detection of
podocalyxin in human
lung lysate using
NB110-41503.
Podocalyxin Antibody
Hematopoietic Stem Cell Marker
NB110-41510
Detection of
podocalyxin in human
lung lysate using
NB110-41510.
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: ICC, IP, WB
The p63 gene is highly expressed in the
basal or progenitor layers of many
epithelial tissues. p63 plays a fundamental
role associated with development and
differentiation.
5
Podocalyxin is a CD34 family member expressed by podocytes, vascular endothelia,
mesothelia, and a subset of hematopoietic progenitors. Podocalyxin appears to
complement CD34 as a useful cell surface marker for hemangioblasts, the common
precursors of hematopoietic and endothelial cells.
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Nucleostemin Antibody
Embryonic Stem Cell Marker
NB100-1569
Detection of
human and mouse
GNL3 in HeLa, 293T
and 3T3 cells using
NB100-1569.
Nucleostemin Antibody
Embryonic Stem Cell Marker
NB100-2896
Staining of human skin
basal cells carcinoma
using NB100-2896.
Nucleostemin Antibody
Embryonic Stem Cell Marker
NB100-1568
Detection of
human and mouse
GNL3 in HeLa, 293T
and 3T3 cells using
NB100-1568.
Species: Hu, Mu
Species: Hu, Mu
Species: Hu, Mu
Applications: IP, WB
Applications: IHC
Applications: IP, WB
Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow, and
cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle
progression in stem cells and cancer cells.
The transcription factor OCT4,
expressed in ES cells and germ cells,
is strongly implicated in the process of
maintaining as well as regaining
stem-cell pluripotency and functions as
a key regulator of mammalian germline
development. It is expressed in
totipotent embryonic stem and germ
cells. A critical level of Oct-4 expression
is required to sustain stem cell
self-renewal and pluripotency.
SSEA Antibodies
Embryonic Stem Cell Markers
SSEA-1 is expressed on the surface
of preimplantation-stage murine
embryos and has been found on
the surface of teratocarcinoma stem
cells, but not on their differentiated
derivatives. SSEA-3 is synthesized
during oogenesis and is present in
the membranes of oocytes, zygotes
and early cleavage-stage embryos.
Biological roles of these
carbohydrate-associated molecules
have been suggested in controlling
cell surface interactions during
development.
Undifferentiated primate ES cells,
human EC and ES cells express
SSEA-3, but not SSEA-1.
Undifferentiated mouse ES cells
express SSEA-1, but not SSEA-3.
SSEA-1 staining has been seen in the
the oviduct epithelium, endometrium,
epididymis, and in some areas of
the brain and kidney tubules in adult
mice.
SSEA1 Antibody
NB100-1831
Species: Hu, Mu
Applications: FACS, ICC, IF
SSEA3 Antibody
NB100-1832
Species: Hu
Applications: FACS, IF, IHC
For research purposes only.
Not for use in humans.
Prices subject to change.
OCT4 Antibody
Embryonic Stem Cell Marker
NB100-2379
Detection of OCT4
in HeLa whole cell
extract using NB
100-2379.
OCT4 Antibody
Embryonic Stem Cell Marker
NB100-41088
Detection of OCT4 in
human liver lysate
using NB100-41088.
Species: Hu
Applications: WB
Species: Hu
Applications: ELISA, WB
Sca-2 Antibody
Hematopoietic Stem Cell Marker
NB100-58797
Staining of
cerebellar Purkinje
neurons using
NB100-58797.
Sox2 Antibody
Embryonic Stem Cell Marker
NB110-37235
Detection of SOX2 in
mouse brain lysate
using NB110-37235.
Species: Hu
Applications: IHC-P, IP, WB
Species: Mu
Applications: IHC, WB
The autosomal dominant cerebellar ataxias
(ADCA) are a heterogeneous group of
neurodegenerative disorders
characterized by progressive degeneration
of the cerebellum, brain stem and spinal
cord.
The SOX (SRY-box containing gene)
gene family encodes a group of
transcription factors defined by the
conserved high motility group (HMG)
DNA-binding domain. They are involved in
the regulation of embryonic development
and in the determination of cell fate.
Telomerase Antibodies
Embryonic Stem Cell Markers
NB100-317
Telomeres are nucleoprotein structures at
the ends of eukaryotic chromosomes.
Telomerase is an enzyme uniquely
associated with immortal cell lines and
is useful for identifying undifferentiated
PSCs.
Staining of normal
pancreas using
NB100-317.
Species: Hu
Applications: FACS, IF, WB
NB100-297
NB120-32020
Detection of hTERT
in MJ90 whole
cell lysate using
NB100-297.
Staining of paraffinembedded human
lung adenocarcinoma
using NB120-32020.
Species: Hu
Applications: FACS, ICC, IHC, WB
Species: Hu
Applications: IF, WB
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6
Thrombopoietin Antibody
Hematopoietic Stem Cell Marker
NB110-68129
Detection of TPO
Lane 1: 100ng mouse
TPO (non-reduced)
Lane 2: 100ng mouse
TPO (reduced).
Species: Mu
Applications: ELISA, WB
TRA 1-60 Antibody
Embryonic Stem Cell Marker
NB100-730
TRA-1-81 and TRA-1-60 are cellsurface proteins involved in cell
differentiation. Cell surface antigens
are powerful tools for characterizing the function and expression
of developmentally regulated cells
during both embryogenesis and
oncogenesis.
Thrombopoietin (TPO) has been shown to
function both as a proliferative and
differentiative factor for megakaryocytes
and as a survival and weakly proliferative
factor for hematopoietic stem cells.
TRA 1-81 Antibody
Embryonic Stem Cell Marker
NB100-1833
Immunofluorescence
staining of
methanol-fixed
NTERA-2 cl.D1 cells
showing membrane
localization using
NB100-1833.
Species: Hu
Applications: FACS, IF, IHC, IP, WB
Detection of TRA1-60 in NTERA-2 cell
lysate using NB100-730.
Species: Hu
S
Applications: FACS, IF, IHC, IP, WB
A
VEGFR2 Antibodies
Hemangioblast/Stem Cell Markers
Receptors for Vascular Endothelial Growth Factor (VEGF), VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase
ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of
embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which
binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.
NB200-208
NB100-686
Staining of
FFPE human
angiosarcoma
using
NB100-686.
Species: Hu, Mu, Rt
Applications: IF, IHC-Fr, IHC-P, WB
Species: Hu, Rt
Applications: ELISA,
FACS, IHC
NB100-527
NB100-627
Species: Hu
Applications: WB
Species: Hu, Mu
Applications: IP, WB
NB110-55547
NB100-530
7
NB100-529
Detection of VEGFR-2
in CSF-1 receptor/
VEGFR2 chimera
transfected lysate
using NB100-529.
Species: Hu
Applications: WB
NB110-55548
Staining of breast
carcinoma using
NB110-55548.
Species: Hu
Applications: IHC
Species: Hu
Applications: WB
NB110-57644
NB110-57149
Detection of
VEGFR2 doublet
in CSF-IR/VEGFR2
chimera transfected
lysate using
NB100-2382.
Species: Hu
Applications: WB
Species: Hu, Mu, Rt
Applications: IHC-P, WB
Detection of VEGFR2
in VEGFR2 induced
HUVEC lysate using
NB100-530.
Staining of
breast carcinoma
using
NB110-55547.
NB100-2382
Staining of
formalin fixed
paraffin embedded
human angiosarcoma
using NB600-1433.
Detection of VEGFR2
in CSF-1/VEGFR2
transfected lysates using
NB100-627.
Lane 1 - 1:2,000
Lane 2 - 1:10,000
Detection of
VEGFR2 in Chimeric
CSF-1R/VEGFR2
using NB100-527.
Species: Hu
Applications: IHC
NB600-1433
Staining of
myocardium section
using NB200-208.
The arrowheads
indicate VEGFR-2
positive endothelial
cells from myocardial
capillaries.
Detection of VEGFR2
in ECV304 cell lysate
using NB110-57644.
Detection of VEGFR2
in ECV304 cell lysate
using NB110-57149.
Species: Hu
Applications: WB
Species: Hu
Applications: WB
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Fibroblast Markers
Fibroblasts (Pan Reticular) Antibody
BM4018
Staining of
reticular fibroblasts
and reticular fibres
with BM4018
antibody.
Fibroblast (Surface Protein) Antibody
SM1214P
Staining of KG1 cells
with mouse anti
human fibroblast
antibody (SM1214P).
Prolyl 4-Hydroxylase Antibody
AF5110
Staining of frozen
rat skin sections
using AF5110.
Species: Hu, Mu
Applications: IHC-Fr
Species:
Hu
Species
i
H
Applications: FACS, IHC, IP
Species: Rt
Applications: ELISA, IHC, WB
Neural Cell Markers
Astrocyte/Astroglia Markers
Astrocytes are star-shaped glial cells that perform
multiple functions in the CNS. They play a significant
role in maintaining normal brain physiology during
development and in adulthood. Astrocytes also provide
alpha Smooth Muscle Actin Antibody
NB120-18460
physical support to neurons, clean up debris within the
brain, provide chemicals to help control fluid
composition surrounding neurons, and provide
nutritional support to neurons.
Survivin Antibody
NB500-201
ABCA1 Antibody
NB400-105
Telophase with
accumulation of
survivin in the midbodies of two
daughter cells.
Staining of human
leiomyosarcoma using NB120-18460.
Staining of prostate
epithelium using
NB400-105.
Species: Bv, Ch, Hu, Ma, Mu, Rt, Bb
Applications: IF, IHC-Fr, IHC-P, WB
Species: Hu, Mu, Ca, Rt, Fe
Applications: IF, WB, IHC-P, IP, ICC.
Species
Species:
Species
i
Ha,
Ha
H
a Hu,
Hu Mu,
H
Mu Rt
M
Applications: FACS, ICC, IF, IHC-P, IP, WB
Smooth muscle vessels alpha actin has
been found in distinct populations of
astrocytes in the adult mouse brain, in
particular in the corpus callosum and the
fornix. However, in the corpus callosum, it
is seen only in parasagittal planes. Thus,
alpha smooth muscle actin represents a
new marker for subsets of astrocytes.
Survivin is also abundantly expressed in
brain tissues (astrocytes and some neurons)
of adult rats following traumatic brain
injury. Survivin has been found
co-expressed with NeuN (mature neuronal
marker) and PCNA (a cell cycle protein).
Survivin might affect regulation of neural
cell proliferative responses after brain
injury.
In the brain, ABCA1 is expressed in
neurons, astrocytes, and microglia and
is induced by liver X receptor (LXR) and
retinoid X receptor (RXR) agonists.
GFAP Antibody
NB300-141
Staining of typical
astrocytic cells using
NB 300-141 in
neurons and glia of
rat forebrain.
Species: Bv, Hu, Mu, Po, Rt, Fe
Applications: ICC, IF, IHC, IHC-Fr,
IHC-P, WB
GFAP Antibody
NB300-142
Rat cortical
neurons and glia in
mixed tissue culture
stained with Chicken
polyclonal to MAP2 NB300-213 (green) at
1/30000 and Mouse
Species: Hu, Ma
monoclonal to GFAP
Applications: IF, WB
- NB300-142 (red) at
1/100.
GLAST Antibody
NB100-1869
GLAST expression begins in the
newborn and persists throughout
life. This consistency and the fact that
GLAST expression is linked to a functional role of astrocytes in glutamate
homeostasis makes it a good marker
for astrocyte identification.
Species: Rt
Applications: FACS, ICC, IHC, WB
Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament
protein family. It is heavily and specifically expressed in astrocytes and certain other
astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in
non-myelinating Schwann cells in peripheral nerves. In addition neural stem cells
frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as
markers of astrocytic cells. In addition many types of brain tumors, presumably derived
from astrocytic cells, heavily express GFAP.
For research purposes only.
Not for use in humans.
Prices subject to change.
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8
General Glial Cell Markers
Glial cells are non-neuronal cells that include microglia
and macroglia cells. The latter includes astrocytes,
oligodendrocytes, ependymal cells, radial glia,
Schwann cells and satellite cells. Glial cells, which are
often referred to as the glue of the CNS, function to
support and protect neurons, maintain homeostasis,
form myelin, and partake in signaling in the central
nervous system (CNS).
The SOX (SRY-box containing gene)
gene family encodes a group of
transcription factors defined by the
Detection of SOX2 in conserved high motility group (HMG)
mouse brain lysate
DNA-binding domain. They are
using NB110-37235 . involved in the regulation of
embryonic development and in the
determination of cell fate, and are
expressed in the Bergmann glia, a
Species: Mu
population of radial glia present in
Applications: IHC, WB
the Purkinje cell layer.
Sox2 Antibody
NB110-37235
Sox2 Antibody
NB110-37235
Staining of human
uterus using
NB110-37235.
Species: Mu
Applications: IHC, WB
Vimentin Antibody
NB110-57645
Staining of paraffinembedded human
melanoma using
NB110-57645.
Vimentin (phospho Ser38) Antibody
NB110-57646
Detection of Vimentin
in 1) untreated and
2) Calyculin A treated
HeLa cell lysate using
NB110-57646.
Vimentin (Phospho Ser72) Antibody
NB110-57647
Detection of Vimentin
in 1) untreated and
2) Calyculin A treated
HeLa cell lysate using
NB110-57647.
Species: Hu, Mu, Rt
Applications: IHC, IP, WB
Species: Hu, Mu, Rt
Applications: WB
Species: Hu, Mu, Rt
Applications: IP, WB
Vimentin (Phospho Ser82) Antibody
NB110-57648
Detection of Vimentin
in 1) AP treated and
2) untreated HeLa +
Calyculin A cell lysate
using NB110-57648.
Vimentin Antibody
NB200-622
Staining of
formalin-fixed,
paraffin-embedded
human osteosarcoma
using NB200-622.
S
Species:
i
Hu,
H Mu,
M Rt
R
Applications: WB
Species: All
Applications: IHC-P, IP, WB
Vimentin Antibody
NB300-223
Rat glial cells in mixed
cerebral cortex cultures
stained with antivimentin (NB 300-223)
[green] and counterstained with anti-GFAP
(NB300-142) [red].
Species: Hu, Mu, Rt
Hoechst dye reveals
Applications: IF
nuclear DNA [blue].
Vimentin is the 10nm or intermediate filament protein subunit found in many kinds of mesenchymal and epithelia cells, in many kinds of
cells in tissue culture, and in developing neuronal and astrocytic precursor cells in the central nervous system. Vimentin frequently forms
co-polymers with other intermediate filament proteins, such as GFAP (in astrocytes), with desmin (in muscle cells) and neurofilament
proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and are generally used to reveal the filamentous
cytoskeleton.
Microglia Markers
Microglia are the smallest glial cells that function
similarly to macrophages in the blood system. They
are the first immune defense in the CNS that seek and
destroy damaged neurons, plaques, and infectious
agents. When infections cross the blood-brain barrier,
microglia cells act to increase inflammation in order to
destroy the infectious agents before they cause damage
to the brain and/or spinal cord. Due to their plasticity,
microglia cells are present in various forms depending
on their location in the body, such as ameboid,
ramified, phagocytic, juxtavascular, and gitter cells.
9
CD11 b/c Antibody
Ferritin Antibody
NB110-40766
NB600-920
Staining of bone
marrow,
myeloid
precursors using
NB110-40766.
Detection of
Ferritin in
HT1080
cells using
NB600-920
using IP.
Species: Hu, Mu
Applications: IHC, IHC-P, WB
Species: Hu
Applications: ELISA, IHC, IP, WB
CD11b is expressed on 8% spleen
cells, 44% bone marrow cells and
less than 1% of thymocytes and
is commonly used as a microglial
marker in nervous tissue.
Ferritin is a a marker for microglia,
especially for reactive microglia and
macrophages.
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Neuronal Markers
Neurons, the functional unit of the nervous system, are
electrically excitable cells that transmit signals throughout the body. Generally composed of a soma, dendritic
tree, and axon, their size, shape, and function varies
greatly.
Acetylcholinesterase Antibody
Early Neuronal Development
NB100-1519
Detection of ACHE in
A431 lysate using
NB100-1519.
Bag 1 Antibody
Neuronal Differentiation
NB110-55489
Staining of paraffinembedded colon
carcinoma using
NB110-55489.
Beta Tubulin 3 Antibody
Dendrite Marker
NB100-1612
Dissociated cell culture
of a neonatal mouse
brain showing beta
Tubulin 3 (green
staining) of neurons.
Species: Hu, Mu
Applications: ELISA, WB
Species: Hu, Rt
Applications: ICC, IHC
Species: Mu
Applications: ICC, IHC
Acetylcholinesterase, or AChE,
hydrolyzes the neurotransmitter,
acetylcholine at neuromuscular junctions
and brain cholinergic synapses, and thus
terminates signal transmission
Bag1 is a multifunctional protein that
blocks apoptosis and interacts with several
types of proteins, including the Bcl 2
family proteins.
Beta III tubulin is abundant in the central
and peripheral nervous systems (CNS and
PNS) where it is prominently expressed
during fetal and postnatal development.
Bcl-2 Antibody
Bcl-2 Antibody
Neuronal Apoptosis Inhibitor
Neuronal Apoptosis Inhibitor
NB100-2087
NB200-572
Staining of
Detection of Bcl-2
human tonsil using
in human lung cell
NB200-572. Note
extract using
absence of staining
NB100-2087.
of reactive cells in the
germinal center.
Species: Hu, Mk
Applications: IHC-P, WB
Species: Hu
Applications: IHC
Bcl-2 Antibody
Neuronal Apoptosis Inhibitor
NB300-900
Detection of Bcl-2
in human lymph
node lysate using
NB300-900.
Bcl-2 Antibody
Neuronal Apoptosis Inhibitor
NB110-55551
Staining of paraffinembedded human
breast carcinoma
using NB110-55551.
Species: Hu, Mu, Rt
Applications: ELISA, WB
Species: Hu, Mu
Applications: FACS, ICC, IHC, IP, WB
This gene encodes an integral outer mitochondrial membrane protein that blocks the
apoptotic death of some cells. The broad range of protective effects of BCL-2 protein
suggests that BCL-2 may interact with a central step in neural cell death.
c-Fos Antibody
Neuronal Activation
NB600-904
Staining of rat
spinal cord uisng
NB600-904.
Species: Hu, Mu, Rt
Applications: IHC-P, IP, WB
c-Fos Antibody
NB120-14285
Detection of c-Fos in
western blot.
Species: Bv, Hu, Mu, Rt
Applications: WB
The Fos proteins have been implicated
as regulators of cell proliferation,
differentiation, and transformation. Fos
was the first transcription factor identified
with a critical function in regulating the
development of skeletal cells.
Calretinin Antibody
NB110-55651
Staining of paraffinembedded Human
mesothelioma using
NB110-55651.
Calretinin Antibody
NB300-707
Detection of
Calretinin rat brain
homogenates using
NB300-707.
Calretinin Antibody
NB200-618
Staining of human
mesothelioma using
NB200-618. Note
cytoplasmic and
nuclear staining of
tumor cells.
Species: Hu, Mu, Rt
Applications: IHC
Species: Hu, Mu, Rt
Applications: IP, WB
Species: Hu, Mu, Rt, Am
Applications: IHC-P
Mesothelial Cell Marker: Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to calbindin family. It is mainly found
in neuronal tissue and is highly expressed in auditory neurons. It has been implicated in a calcium buffer, calcium sensor, and as a regulator
of apoptosis. Calretinin is considered a specific marker of mesothelial cells; it is the only marker that has the utility in distinguishing between
sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas. It is widely used in the panel of makers for distinguishing mesothlioma
from adenocarcinoma.
For research purposes only.
Not for use in humans.
Prices subject to change.
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10
ChAT Antibody
Cholinergic Neuron Marker
NB100-40794
Detection of ChAT in
mouse brain lysate
using NB100-40794.
ChAT Antibody
Cholinergic Neuron Marker
R-043-100
Staining of rat facial
nucleus using
Rabbit antibody to ChAT
(R-043-100) at 1:2000
dilution.
S
Species:
i
Rt,
Rt Mu
M
Applications: ELISA, WB
Species: Hu, Rt, Rb, Gp
Applications: ELISA, IHC, WB
ChAT serves as a specific marker
for cholinergic neurons in both
peripheral and central nervous
systems. It is also present at
parasympathetic postganglionic
fibres.
ELF Antibody
Neuronal Precursor Cell Marker
NB100-68253
Detection of Human
ELF1 in HeLa whole
cell lysates using
NB100-68253.
ELF Antibody
Neuronal Precursor Cell Marker
NB100-40828
Detection of SPTBN1
in HeLa and 293T cells
using NB100-40828.
ELF Antibody
Neuronal Precursor Cell Marker
NB100-55272
Staining of human
prostate
adenocarcinoma
using NB100-55272.
Species: Hu
Applications: WB
Species: Hu, Mu
Applications: WB, IP
Species: Hu
Applications: IHC-P
Spectrins play a pivotal role in axonal transport, neurite extension, the organization of synaptic vesicles, as well as for protein sorting in
the Golgi apparatus and cell membrane.
HSV-1 Antibody
Neuronal Latency Marker
NB110-57251
10-well HSV-1
slides, 10-well HSV-2
slides, anti-MouseFITC F(ab)2 with
counterstain.
Following primary
infection in humans,
herpes simplex virus type
1 (HSV-1) establishes
latent infections in
sensory neurons.
Species: All
Applications: ELISA, IF, WB
MAP2 Antibody
Neuronal Dendrite Marker
NB300-213
Rat neurons stained
with anti-MAP2
(NB300-213) [green]
and anti-GFAP
(NB300-142) [red].
Species: Bv, Hu, Mu, Rt
Applications: IF, WB
Microtubules are associated with a
family of proteins called microtubule
associated proteins (MAPs), which
includes the protein (tau) and a group
of proteins referred to as MAP1, MAP2,
MAP3, MAP4 and MAP5. Antibodies to
MAP2 are excellent markers on
neuronal cells, their perikarya and
neuronal dendrites.
NQO1 Antibody
Neuronal Injury Marker
NB200-209
Detection of NQO1
in A549 lysates using
NB200-209. Lane 1:
0.5 ug/ml. Lane 2: 2
ug/ml.
Nestin Antibody
Neuronal Stem Cell Marker
NB300-266
Visualization of nestin
in PC-3 cells using
NB300-266.
Courtesy of Dolnick
Lab, Roswell Park
Cancer Institute.
Species: Ca, Hu, Mk, Rt
Applications: IF, IHC, IP, WB
Species: Hu
Applications: ICC, IHC, IF, WB
Neuronal damage is associated with an
increased activity of NQO1.
Nestin is a Class VI intermediate filament expressed in the developing central nervous
system (CNS) in early embryonic neuroepithelial stem cells.
Neurofilament Light Antibody
NB300-133
Detection of NF-L in
whole rat cerebellum
homogenate using
NB300-133.
Neurofilament Medium Antibody
NB300-134
Culture of adult
neural cells. Mature
neurons can be
identified by
morphology and
staining.
Neurofilament Heavy Antibody
NB300-135
Section of rat spinal
cord stained with
NB300-135 (green)
and NB110-58869
(red).
Species: Bv, Hu, Ma, Mu, Po, Rt, Fe, Av
Applications: ICC, IF, IHC-Fr, IHC-P, WB
Species: Hu, Ma, Mu, Av
Applications: IHC, WB
Species: Hu, Ma, Mu, Mk
Applications: IHC-Fr, IHC-P, WB
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three
major proteins called NF-L, NF-M and NF-H. NF-L runs on SDS-PAGE gels at about 68kDa; NF-M at 145-170 kDa; NF-H at 180-220 kDa.
Antibodies to the neurofilaments are useful for identifying neuronal cells and their processes in tissue sections, and can also be useful in the
diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig’s disease or Alzheimer’s disease.
11
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PGP9.5/UCHL1 Antibodies
Peripheral Nerve Fiber Markers
PGP9.5 Antibody
NB300-675
UCLH1 Antibody
NB110-58872
PGP9.5 Antibody
NB600-1160
Staining of
human brain
using NB300-675.
Staining of rat
abdominal tissue
using NB600-1160.
Species: Mu, Hu
Applications: IHC, WB
Species: Hu, Rt
Applications: ELISA, IHC-P, WB
PGP9.5 Antibody
NB110-58874
S
Shows
rat mixed
n
neuron/glial cultures
sstained with Rabbit
UCHL1 (green). Blue
U
iis a DNA stain.
Shows rat mixed
neuron/glial cultures
stained with chicken
UCHL1 (green) and
rabbit antibody to
glial fibrillary acidic
protein (GFAP-red),
Species: Hu, Rt
NB300-141. Blue is
Applications: IF, WB a DNA stain.
Ubiquitin C-terminal hydrolase 1 (UCHL1) was originally identified as a major
component of the neuronal cytoplasm from 2-dimensional gel analysis of brain tissues,
and was given the name PGP9.5. The protein is extremely abundant representing 1-2%
of total brain protein. It was later found that a ubiquitin C-terminal hydrolase enzyme
activity was associated with the PGP9.5 protein, resulting in the renaming of PGP9.5 to
ubiquitin C-terminal hydrolase 1.
Since UCHL1 is heavily expressed in neurons, antibodies to UCHL1 can be used to
identify neurons in histological sections and in tissue culture. The great abundance of
this protein in neurons means that it is released from neurons in large amounts following
injury or degeneration, so the detection of UCHL1 in CSF and other bodily fluids can
be used as a biomarker. UCHL1 was also discovered as a gene mutated in some rare
famial forms of Parkinson’s disease. Interestingly, a common allelic variant of UCHL1,
the S18Y polymorphism is actually protective against Parkinson’s disease.
Species:
Species:
i
Hu,
Hu Rt
Applications: IF, WB
Synapsin 1 Antibody
NB300-312
Detection of
synapsin 1
in rat
hippocampal
lysate using
NB300-312.
Synapsin 1 Antibody
NB300-104
Species: Hu, Mu, Rt
Applications: WB
Species: Hu, Mu, Rt
Applications: IF, IHC, IP, WB
Detection of
synapsin 1
in rat
hippocampal
lysate using
NB300-104.
Synapsin I plays a key role in synaptic plasticity in the
brain. This effect is due in large part to the ability of
the synapsins to regulate the availability of synaptic
vesicles for release. In addition to its role in plasticity,
the expression of synapsin I is a precise indicator of
synapse formation. Thus Synapsin I
immunocytochemistry provides a valuable tool for
the study of synaptogenesis. The role of synapsin in
synaptic plasticity and in synaptogensis is regulated by
phosphorylation.
Oligodendrocyte Markers
Oligodendrocytes provide support to axons and
produce insulating myelin sheaths. The CNS depends
on this insulation to reduce ion leakage in order to
increase overall nerve conduction speed. When myelin
Amphoterin Antibody
NB100-2322
sheaths are degenerated oligodendrocytes attempt to
replace them, however, in multiple sclerosis patients
oligodendrocytes themselves are destroyed thus
compromising their ability to perform repairs.
CNPase Antibody
NB100-1935
CNPase Antibody
NB110-79874
Detection of
CNPase in normal
brain tissue lysate
using NB110-79874.
Detection of HMGB1 in
whole cell HeLa lysate
using NB 100-2322.
Adult mouse brain
showing CNPase
(brown staining)
in white matter tracts
and the granule
cell layer of the
cerebellum.
Species: Hu, Mu
Applications: WB
Species:
Species:
i
Hu
Hu
Applications: WB
The onset of amphoterin expression, prior
to the expression of myelin-specific antigens, makes amphoterin a useful marker
for studying oligodendrocyte development.
2’,3’-cyclic nucleotide 3’-phosphodiesterase (CNPase) is associated with brain tubulin
and acts as a microtubule-associated protein in promoting microtubule assembly and
distribution. CNPase is used as a marker of cell differentiation in the CNS as it is expressed primarily in committed oligodendroglial progenitors and terminally-differentiated
oligodendrocytes.
For research purposes only.
Not for use in humans.
Prices subject to change.
Species: Mu
Applications: ICC, IHC
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12
MAP-4 Antibody
NB100-74615
Olig2 Antibody
NB110-41440
MOG Antibody
NB300-948
D
Detection
of
human MAP4 in HeLa
h
ccell lysate
using NB100-74615.
u
Detection of Olig 2
in Jurkat whole
cell lysates using
NB110-41440.
Detection of MOG in
human brain lysate
using NB300-948.
Species:
Species:
i
Hu
Hu
Applications: IP, WB
Species: Hu, Mu, Rt
Applications: ELISA, WB
Species: Hu, Mu
Applications: WB
Microtubule-associated protein 4 is a
major non-neuronal microtubuleassociated protein and is a marker for
astroglia and oligodendroglia cells.
Myelin-Oligodendrocyte Glycoprotein
(MOG) is a surface marker of
oligodendrocyte maturation.
The oligodendroglial lineage marker,
Olig2, is expressed in neural progenitors
and oligodendroglia and is essential for
oligodendrocyte development.
Nestin Antibody
NB600-876
Nestin Antibody
NB100-1604
Detection of Nestin
in MEF whole cell
lysates using
NB600-876.
A tissue section of
mouse brain showing
Nestin (green
staining) in neural
stem cells of the
ventricular zone of
the CNS.
Species: Mu
Applications: ICC, IHC
Species: Mu
Applications: WB
Nestin is a marker of oligodendrocyte
lineage cells. Nestin is a Class VI
intermediate filament expressed in the
developing central nervous system
(CNS) in early embryonic
neuroepithelial stem cells. This protein
has been widely used as a predominant
marker for stem / progenitor cells,
glioma cells, and tumor endothelial
cells. Furthermore, it is a superior
angiogenic marker to evaluate
neovascularity of endothelial cells in
tumors.
Schwann Cell Markers
Schwann cells are a type of glial cell that function as
support cells for the PNS, similar to oligodendrocytes
of the CNS. They mainly provide myelin insulation to
AN2 Antibody
NB300-750
peripheral axons in order to increase signal conduction.
Schwann cells also aid in clearing debris and guide
axon regrowth in the PNS.
AN2 Antibody
NB100-61654
Detection of AN2 in
mouse eye lysate using
NB100-61654.
Detection of PAX6 in
rat whole eye extract
using NB 300-750.
Species: Mu, Hu, Ch, Xp, Rt, Sh
Applications: WB
Species:
Species:
i
Mu
Mu
Applications: ELISA, WB
AN2 is expressed by immature Schwann cells in vitro and in vivo and downregulated as
the cells upregulate myelin genes.
Ran-1 Antibody
NB100-1384
Species: Hu, Mu, Rt
Applications: IHC-Fr, IHC-P, WB
Laminin Antibody
NB300-144
Detection of
laminin in EHS (1)
and heart (2) lysates
using NB300-144.
SCIP Antibody
NB100-1359
D
Detection
of Ran-1
iin 3T3 cell lysate usiing NB100-1384.
13
Laminin Antibody
NB300-144
Staining of rat spinal
cord and dorsal
root tissue using NB
300-144. Pepsin
antigen retrieval was
performed.
Detection of SCIP
in human brain
lysate using
NB100-1359.
Species:
Species:
i
Hu,
Hu Mu
Mu
Applications: ELISA, WB
Species: Hu
Applications: WB
Ran-1 is a marker for normal
Schwann cells and is associated with
adult non-myelin-forming Schwann
cells.
SCIP, also known as Tst-1 or Oct-6, is
expressed in proliferating Schwann
cells in the PNS and O2A progenitor
cells in the developing CNS.
Species: Hu, Mu, Rt
Applications: IHC-Fr, IHC-P, WB
Laminin is a marker for human
Schwann cells in vitro. Laminin
antibodies are widely used to label
blood vessels and basement
membranes.
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Organelle Markers
Autophagic Vesicle Markers
Autophagy is an evolutionarily conserved process
responsible for the bulk degradation of intracellular
material. In autophagy, cytoplasmic components are
engulfed by double-membrane-bound structures
APG8a Antibody
R-146-100
(autophagosomes) and delivered to lysosomes/vacuoles
for degradation.
Recent reports indicate that autophagy plays a crucial
role in many different pathologies.
APG8b Antibody
R-155-100
Confocal
microscopy on
immunofluorescently
detected MAP1LC3 A
in cytospin-isolated
human white blood
cells.
APG8c Antibody
R-140-100
Confocal
microscopy on
immunofluorescently
detected MAP1LC3 C
in cytospin-isolated
human white blood
cells.
Detection of APG8b
in Olfactory cell line
(Odora) lysate using
R-155-100.
Species: Hu, Rt
Applications: IF, IHC, WB
Species: Hu, Rt
Applications: IF, IHC, WB
Species: Hu
Applications: IF, IHC, WB
LC3 Antibody
NB100-2220
LC3 Antibody
NB100-2331
LC3B Antibody
NB600-1384
Staining of brain,
cerebral cortex, cell
processes in gray
matter using
NB100-2331
Staining of brain,
cerebral
cortex, neurons
using NB100-2220.
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Hu, Mu
Applications: IHC, IHC-P, IP, WB
Staining of treated
U373-MG (human
glioblastoma) cells
using NB600-1384.
Species: Hu, Mu
Applications: ICC, IF, IHC, WB
LC3 is the only known mammalian protein identified that stably associates with the autophagosome membranes. LC3-I is cytosolic and
LC3-II is membrane bound and enriched in the autophagic vacuole fraction. The detection of LC3-I to LC3-II conversion is a useful and
sensitive marker for distinguishing autophagy in mammalian cells.
Centrosome Markers
The centrosome is the main microtubule organizing
center (MTOC) of the cell and acts as a regulator of
cell-cycle progression. Centrosomes are present in
higher eukaryotic cells, but not plant cells. The
centrosome is composed of two centrioles surrounded
by an amorphous mass of pericentriolar material
gamma Tubulin Antibody
NB100-1628
Detection of gamma
Tubulin in chicken
fibroblasts using
NB100-1628.
Species: Bv, Ca, Ch, Ha, Hu, Mu, Rt, Xp
Applications: ELISA, IHC, WB
Gamma tubulin is responsible for
binding microtubule minus ends and
mediating the link between
microtubles and the centrosome.
For research purposes only.
Not for use in humans.
Prices subject to change.
(PCM). The PCM contains proteins responsible for
microtubule nucleation and anchoring. Each centriole is
composed of nine triplet microtubule blades in a
pinwheel structure. Cancer cells often have an
abnormal number of centrosomes, which may be of
biological significance.
Pericentrin/Kendrin Antibody
NB100-61071
Detection of
Human Pericentrin/
Kendrin in HeLa
cell extracts using
NB100-61071.
Pericentrin/Kendrin Antibody
NB100-61072
Detection of
Human Pericentrin/
Kendrin in HeLa
cell extracts using
NB100-61072.
Species: Hu
Applications: IP
Species: Hu
Applications: IP, WB
Pericentrin binds to calmodulin and is
expressed in the centrosome. It is an integral
component of the pericentriolar material
(PCM). The protein contains a series of
coiled-coil domains and a highly conserved
PCM targeting motif called the PACT domain
near its C-terminus. The protein interacts
with gamma-tubulin and is likely important
to normal functioning of the centrosomes,
cytoskeleton, and cell-cycle progression.
Pericentrin/Kendrin Antibody
NB100-68277
Staining of
HeLa
cells using
NB100-68277.
Species: Hu
Applications: ICC
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14
Endosome Marker
EEA1 Antibody
NB300-502
Endosomes are membrane-bound vesicles that are
formed by endocytosis. Endocytosis involves
invagination of the plasma membrane to encircle a
substance and budding to release the vesicle.
Endosomes function to either transport their contents to
a lysosome for degradation or to transport substances
between different portions of the external cell
membrane, the latter of which is essential for epithelial
cells whose polarity differs on each side of the
membrane.
Staining of HeLa cells
using NB300-502.
Species: Ca, Ha, Hu, Mu, Rt, Xp
Applications: IF, IP, WB
Early endosomal antigen 1 (EEA1) is a 162
kDa membrane bound protein component
specific to the early endosome and is
essential for fusion between early endocytic
vesicles.
Endoplasmic Reticulum Markers
The endoplasmic reticulum is an organelle of
interconnected tubules, vesicles, and cisternae. Its
specific functions involve protein translation and folding,
WFS1 Antibody
NB100-1918
Immunoprecipitation
of WFS1 using NB
100-1918.
Precipitated lysate
is INS-1.
Species: Hu, Mu,
M Rt
Applications: IF, IHC-Fr, IP, WB
WFS1 plays an important role in
maintaining homeostasis of the
endoplasmic reticulum (ER) in the pancreas.
transport of proteins to the cell membrane, secretion of
cellular proteins, sequestration of calcium, and
production and storage of macromolecules.
PDI Antibody
NB100-1921
Protein disulfide isomerase (PDI) is
an acidic 55 kDa thyroid
hormone-binding protein that
appears to be identical to the glialp55 protein. It has been suggested
to be involved in disulfide-bond
formation and isomerization, as well
as the reduction of disulfide bonds in
proteins.
ERp29 Antibody
NB300-523
Species: Rt
Applications: ICC, IP, WB
ERp29 resides in the lumen of the
ER and is thought to play a role in
the processing of secretory proteins
within the ER.
Calreticulin Antibody
NB600-103
Detection of
calreticulin in
human kidney lysate
using NB 600-103.
Calreticulin Antibody
NB600-101
Immunofluorescence
staining of
Calreticulin in HCT15
colon cancer cells
using NB 600-101.
Species: Hu
Applications: WB
Species: Bv, Ha, Hu, Mu, Rt
Applications: ICC, IF, IHC, IP, WB
Calreticulin is a multifunctional, highly conserved Ca2+ -binding protein that is localized to
the endoplasmic reticulum.
GRP78/BiP Antibody
NB300-520
Detection of GRP78
in liver, J77, CHQ
and Akt-29 cells
using NB300-520.
15
Staining of
rat thyrocytes using
NB 300-523.
Species: Bv, Ca, Gp, Ha, Hu, Mu, Mk, Rt
Applications: IF, IP, WB
ERp57 Antibody
NB100-1143
Detection of ERp57
in HepG2 lysate using
NB100-1143.
Species: Hu
Applications: ELISA, WB
ERp57 functions together with
calnexin and calreticulin as a
molecular chaperone of glycoprotein
biosynthesis within the ER.
Heme oxygenase-1 Antibody
NB110-57028
GRP94 Antibody
NB100-41095
Immunofluorescent
staining of HeLa
cells using
NB110-57028.
Detection of GRP94
in 3T3 lysate using
NB100-41095.
Species: Ha, Rt, Mu
Applications: IF, IP, WB
S
i
M
Species:
Mu
Applications: ELISA, WB
Within the ER, misfolded proteins are
detected by Bip(GPR78).
Glucose-regulated protein 94, also
known as Grp94 or gp96, is an
abundant resident endoplasmic
reticulum (ER) lumenal stress protein.
Species: Hu, Mu
Applications: ICC, IHC, IP, WB
HO-1 catalyzes the NADPH, O2 and
cytochrome P450 reductase dependent
oxidation of heme to carbon monoxide,
iron and biliverdin that is immediately
reduced to bilirubin.
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Golgi Complex Markers
The Golgi apparatus is a membrane-bound stack of
cisternae that processes proteins and lipids synthesized
in the ER and packages them for transport elsewhere in
the cell. The Golgi is responsible for glycosylating
proteins synthesized in the ER and also for cleaving
some proteins into smaller fragments. The Golgi
packages these products in vesicles for transport, either
to destinations inside of the cell or outside of it.
GlcNAc transferase Antibody
NB100-57845
Golgi Marker 58K Antibody
NB600-412
Glucose-6-Phosphate Antibody
NB100-236
Detection of G6PD
in HUVEC cells
using NB100-236..
Detection of GlcNAc
in rat pancreas lysate
using NB100-57845.
Staining of HeLa
cells using
NB600-412.
Species: Ca, Ha, Hu, Rt
Applications: ICC, IF, IHC, WB
Species: Rt, Mu
Applications: ELISA, WB
Species: Hu, Mu
Applications: IP, WB
58K protein antibodies are
excellent for use as markers for the
Golgi complex.
GlcNAc transferase is present as an
integral Golgi membrane protein
and at least the catalytic center of
the transferase is on the lumenal
side of the vesicles.
Glucose-6-Phosphate is an
indigenous component of Golgi
membranes.
P58 Antibody
NB110-57306
Syntaxin-6 Antibody
NB100-2920
Detection of
Syntaxin-6 in human
lymph node lysate
using NB100-2920.
Detection of p58
in HeLa cell lysate
using NB110-57306.
S
Species:
i
Hu
H
Applications: WB
Species: Hu
Applications: ELISA, WB
P58 is a marker of pre-Golgi intermediate
compartment (IC) and a putative marker
for peripheral punctate pre-Golgi intermediates and the cis-Golgi network.
Syntaxin-6 is primarily on the trans-Golgi
network (TGN), where it partially
colocalizes with the TGN adapter protein
AP-1 on clathrin-coated membranes.
VPS45 Antibody
NB100-2431
TGN38 Antibody
NB110-40768
Species: Mu, Rt
Applications: IF, WB
TGN38 Antibody
NB110-60519
Immuno
fluorescence
staining of TGN38
in 3%
paraformaldehydefixed NRK cells.
VPS45 Antibody
NB100-41372
Detection of VPS45
in human
peripheral blood
mononucleocyte
lysate using
NB100-41372.
Detection of VPS45 in
human placenta lysate
using NB100-2431.
Species: Hu
Applications: ELISA, WB
Species: Hu
Applications: WB
VPS45 is a member of the sec1 family implicated in Golgi to prevacuolar
compartment trafficking in yeast. Mammalian VPS45 is found in multiple tissues, is
partially membrane associated, and is enriched in the Golgi region.
TGN46 Antibody
NB110-62093
Species: Hu, Mk
Applications: IF, WB
Species: Mu, Rt
Applications: IF, IHC-P, WB
TGN38 is a a 38 kDa protein which
has been shown to be predominantly
localized to the trans Golgi network.
TGN46 Antibody
NB110-60520
TGN46 Antibody
NB110-40769
Immunofluorescence
staining of
human TGN46 in 3%
paraformaldehydefixed HeLa cells.
Immunofluorescence
staining of human
TGN46 in 3%
paraformaldehydefixed HeLa cells.
Detection of TGN46
in HeLa cell lysate
using NB110-40769.
Species: Hu, Mk
Applications: IF, WB
Immunofluorescence
staining of TGN38
in 3%
paraformaldehyde-fixed
NRK cells.
Species: Hu, Mk
Applications: IF, IHC-P, WB
TGN46 is localized primarily in the Trans-Golgi network. TGN46 has been reported as being the best available marker for human
trans-Golgi network.
For research purposes only.
Not for use in humans.
Prices subject to change.
FAX: 303.730.1966 • WEB: www.novusbio.com
16
Lysosome Markers
Lysosomes are membrane-bound vacuoles which play
a critical role in cellular metabolism. These organelles
participate in endocytosis, the synthesis and assembly of
LAMP1 Antibody
NB120-19294
acid hydrolases, act as sites for digestion of foreign
materials and for specialized autolytic cellular
processes.
LAMP2 Antibody
NB110-11470
Staining of mouse
astrocytes
using NB110-11470.
Immunofluorescence
staining of Lamp1
(red) in HeLa cells
using N120-19294.
LIMPII/lgp85 Antibody
NB400-129
Staining of LIMP II in
rat infarctzone tissue
using NB 400-129
with a DAB detection
system.
Species: Hu
Applications: IF
Species: Ha, Hu, Mu, Mk, Rt, Rb
Applications: ICC, IF, IHC, IHC-P, IP, WB
Species: Ca, Hu, Mu, Rt
Applications: ICC, IHC, IP, WB
Lamp1, also known as lysosome
associated membrane protein 1, is
a heavily glycosylated membrane
protein of the lysosome.
Lysosome-associated membrane
protein 2 (LAMP 2), also known as
lgp2 or lgp110, is a type 1 integral
membrane protein that is transported from the trans-Golgi network to
endosomes and then lysosomes.
LIMP II is ubiquitously expressed
in most higher organisms and is a
major lysosomal and endosomal
membrane marker.
Rap1 Antibody
NB100-292
Rap1 Antibody
NB110-57453
Localization of RAP1
to Telomeres with
TRF2 by
Immunofluorescence,
using NB 100-292.
Sample: HeLa cells.
Species: Hu
Applications: IF, IP, WB
Rap1 Antibody
NB110-57454
Staining of paraffinembedded human
stomach carcinoma
using NB110-57453.
Species: Hu, Mu, Rt
Applications: FACS, ICC, IHC, IP, WB
Staining of paraffinembedded human
breast cancer tissue
using NB110-57454.
Species: Hu, Mu, Rt
Applications: FACS, ICC, IHC, IP, WB
Rap1A and Rap1B proteins were localized to late endocytic compartments (late endosomes/lysosomes) in fibroblasts.
Mitochondrial Markers
The mitochondrion is a compartmentalized, dualmembraned organelle that is responsible for most
energy production in the cell. Mitochondria contain
their own DNA and ribosomes. The primary function of
mitochondria is to convert energy from glucose into ATP
via oxidative phosphorylation via the Krebs Cycle.
Cytochrome c Antibody
NB100-56503
Detection of
Cytochrome C in
HeLa cell lysate using
NB100-56503.
Cytochrome c Antibody
NB300-1068
Staining of heart
tissue using
NB300-1068.
Species: Dr, Ha, Eq, Hu, Mu, Rt
Applications: ICC, IF, WB
Species: Hu
Applications: ELISA, IHC-P, WB
GFP Antibody
NB100-1770
GFP Antibody
NB600-597
GFP Antibody
NB600-303
Recombinant GFP
detected using
NB600-303.
Species: All
Applications: ICC, IHC-P, IP, WB
Cytochrome c is released from
mitochondria after tissue injury. It is an
electron transporting protein that
resides within the intermembrane space of
the mitochondria, where it plays a critical
role in the process of oxidative
phosphorylation and production of cellular
ATP.
GFP recombinant
protein detected
with NB 100-1770
polyclonal anti-GFP
antibody.
Western blot of GFP
recombinant protein
detected with
NB600-597.
Species: All
Applications: ELISA, IHC, WB
Species: All
Applications: ELISA, WB
GFP, green fluorescent protein, is a marker for subcellular localization and as a label for plant mitochondria in vivo.
17
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Glutamate dehydrogenase Antibody
NB600-853
HSP60 Antibody
NB110-57063
Staining of paraffinembedded human
human breast
carcinoma using
NB110-57063.
Detection of
Glutamate
dehydrogenase
in bovine liver
preparations using
NB600-853.
HSP70 Mitochondrial Antibody
NB300-527
Staining of
human
peripheral blood
mononucleocyte
lysate using
NB300-527.
Species: Bv
Applications: ELISA, WB
Species: Hu, Mu, Rt
Applications: IHC, WB
Species: Hu, Mu
Applications: ICC, IP, WB
Glutamate dehydrogenase has long been
used as a marker for mitochondria in brain
and other tissues.
HSP60 is a transiently expressed
mitochondrial protein.
HSP70 is known to have been acquired
from the proto-mitochondrial
endosymbiont.
GRK2 Antibody
NB100-2831
GRK2 Antibody
NB300-156
Detection of GRK2 in
Daudi cell lysate
using NB100-2831.
NB300-156 (green)
versus NF-M (red, NB
300-134), in rat
cortex, showing
mostly large
pyramidal neurons.
Species: Hu, Bv, Rt
Applications: IHC, WB
Species: Hu
Applications: ELISA, WB
GRK2 is found in many cell types and
may also have a role in the regulation of
the microtubular cytoskeleton. The levels
of GRK2 enzymatic activity, protein and
mRNA are all elevated in a variety of
human heart disease states, and the effect
of this may contribute to the reduced
effectiveness of the beta-adrenergic
system in these disease states. GRK2 is
also overexpressed in Alzheimer disease
and is an early marker of brain mitochondrial lesions.
Mitochondrial Marker Antibody
NB120-17857
Staining of human
liver using
NB120-17857.
VDAC1 Antibody
NB100-695
Species: Ca, Hu, Mu, Rt, Fe
Applications: IF, IP, WB
Species: Hu
Applications: IHC-P
Species: Hu, Rt
Applications: ELISA, WB
Analysis of the human heart mitochondrial
proteome shows that mitofilin is one of the
most abundant mitochondrial proteins.
NB120-17857 recognizes a 60kDa
non-glycosylated protein component of
mitochondria found in human cells. It can
be used to stain the mitochondria in human
samples as a mitochondrial-marker in
subcellular fractions.
VDAC1 is an outer membrane
mitochondrial protein. VDACs are highly
expressed in heart, liver and skeletal
muscle, where concentrations of
mitochondria are at their highest.
Mitofilin Antibody
NB100-1919
Staining of HeLa cells
using NB100-1919.
.
Nuclear Markers
The nucleus is the central organelle of the cell,
containing a cell’s DNA and coordinating the actions of
the cell and the other organelles within the cell.
Surrounded by the nuclear envelope, the nucleus is
responsible for the control of cell division and the
NUP214 Antibody
NB110-40634
direction of protein synthesis within the cell. The
nucleolous, a membraneless organelle lying within the
nucleus, manufactures ribosomes for protein synthesis
in the cell.
Histone H1 Antibody
NB300-373
Staining of
human ovarian
carcinoma using
NB110-40634.
Detection of VDAC1
in rat heart lysate
using NB100-695.
Detection of Histone
H1 in calf thumus using NB300-373.
Fibrillarin Antibody
NB300-269
Human SH-SY5Y
cells stained with
NB300-269, showing
prominent specular
nucleolar stainingNB.
Species: Hu
Applications: ICC, IHC, IHC-P
Species: Bv, Ch, Hu, Mu, Rb, Rt
Applications: IHC, WB
Species: Hu
Applications: WB
Nucleoporin 214 (NUP214) is required for
CRM1-mediated nuclear protein export as
well as cell cycle progression.
Somatic H1 may act as a marker of nuclear
reprogramming.
Fibrillarin is an snRNP protein involved in
pre-ribosomal RNA processing.
For research purposes only.
Not for use in humans.
Prices subject to change.
FAX: 303.730.1966 • WEB: www.novusbio.com
18
Cancer Markers
Breast Cancer
Breast cancer is the most common cancer in women
and is second to lung cancer as the most common
non-skin cancer overall. Approximately 200,000 cases
of breast cancer are diagnosed in women every year in
Androgen Receptor Antibody
NB120-9474
the United States alone, with an additional 2,000 cases
diagnosed in men. There will be an estimated 40,000
women and 450 men who die in 2008 from breast
cancer in the United States.
Androgen Receptor Antibody
NB300-615
Bcl-2 Antibody
NB200-572
Staining of formalinfixed, paraffinembedded
human tonsil using
NB200-572.
Staining of
primate brain using
NB300-615.
Staining of formalin
fixed paraffin embedded human prostate
using NB120-9474.
Species: Hu
Applications: IHC, WB
Species: Hu, Mu, Mk, Rt
Applications: ICC, IHC, IP, WB
Species: Hu, Mk
Applications: IHC-P, WB
Beta-Catenin Antibody
NB110-56924
CAIX Antibody
NB100-417
CaR Antibody
NB300-601
Staining of
Rat-1
cells using
NB300-601.
Staining of human
RCC tumor
cryosections using
NB100-417.
Immunofluorescent
staining of A431 cells
using NB110-56924.
Species: Hu, Mu
Applications: ICC, IHC, IP, WB
Species: Ca, Hu
Applications: IF, IHC-P, WB
Species: Hu, Rt
Applications: ICC, IHC, IP, WB
CD24 Antibody
NB110-500
Cyclin A Antibody
NB110-56899
Cyclin A Antibody
NB110-14736
Staining of
formalin fixed
paraffin
embedded
human tonsil using
NB110-14736.
Staining of paraffinembedded skin
carcinoma using
NB110-56899.
Staining of formalinfixed, paraffinembedded human
liver using
NB110-500.
Species: Hu
Applications: IHC
Species: Hu
Applications: ICC, IHC, IP, WB
Species: Hu
Applications: IHC, WB
Cyclin A Antibody
NB110-56898
Cyclin E Antibody
NB110-56904
Cyclin E Antibody
NB110-56905
Immunofluorescent
staining of HeLa cells
using NB110-56898.
Staining of paraffinembedded human
breast carcinoma
using NB110-56905.
Immunofluorescent
staining of HeLa cells
using NB110-56904.
Species: Hu
Applications: ICC, IP, WB
Species: Hu
Applications: FACS, ICC, IP, WB
Species: Hu
Applications: ICC, IHC, IP, WB
DAP-kinase Antibody
NB110-56925
DAP-kinase Antibody
NB110-56926
ErbB2 Antibody
NB100-1739
Staining of
HeLa cells using
NB110-56925.
Species: Hu
Applications: ICC, IHC, IP, WB
19
Staining of
human breast
adenocarcinoma using
NB100-1739.
Immunohistochemical
staining of paraffinembedded human liver
carcinoma using
NB110-56926.
Species: Hu, Mu, Rt
Applications: FACS, IHC, WB
Species: Hu
Applications: IHC
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ErbB-2 Antibody
NB110-55529
ErbB-2 Antibody
NB110-57022
ErbB-2 Antibody
NB110-57021
Immunohistochemical
staining of paraffinembedded Human
breast carcinoma
using NB110-57021.
Staining of breast
carcinoma using
NB110-55529.
Immunohistochemical
analysis of paraffinembedded human
breast carcinoma using
NB110-57022.
Species: Hu
Applications: FACS, IHC, IP, WB
Species: Hu
Applications: IHC
Species: Hu
Applications: IHC
ErbB-2 Antibody
NB110-57023
EZH2 Antibody
NB110-56975
GATA3 Antibody
NB600-1184
IHC staining of
paraffin embedded
human tonsil using
NB600-1184.
Immunofluorescent
staining of HeLa cells
using NB110-56975.
Immunohistochemical
staining of paraffinembedded human
breast ductal
carcinoma in situ
using NB110-57023.
Species: Hu
Applications: FACS, ICC, IHC, IP
Species: Hu, Mu, Rt
Applications: FACS, ICC, IF, IP, WB
Species: Hu
Applications: IHC, WB
GCDFP-15 Antibody
NB110-66658
Glut-1 Antibody
NB120-15310
HIF-1 alpha Antibody
NB100-479
Staining of
placenta, villi using
NB100-479.
Staining of human
esophagous using
NB120-15310.
Immunohistochemical
staining of paraffinembedded human
breast carcinoma using
NB110-66658.
Species: Hu
Applications: FACS, ICC, IHC, WB
Species: Hu, Rt
Applications: IHC-P
Species: Hu, Mu, Mk, Rt
Applications: IHC, WB
HSP70 Antibody
NB110-57064
Ki67 Antibody
NB500-170
KPNA2 Antibody
NB100-1371
Staining of green
formaldahyde-fixed
HeLa with
endogenously
expressed Histone
H2B-GFP fusion as
DNA marker.
Staining of FFPE
human tonsil using
NB500-170.
Immunohistochemical
staining of paraffinembedded human
prostate carcinoma
using NB110-57064.
Species: Hu
Applications: FACS, IHC, IP, WB
Species: Hu, Mu, Po, Rt
Applications: ICC, IF, IHC-Fr, IHC-P
Species: Hu
Applications: ELISA, ICC, IHC, WB
Laminin Antibody
NB300-144
MDM2 Antibody
NB100-62269
MMP-1 Antibody
NB110-57211
Immunohistochemical
staining of paraffinembedded human
cervical carcinoma
using NB100-57211.
Staining of MDM2human breast
carcinoma using
NB100-62269.
Staining of rat spinal
cord and dorsal root
paraformaldehyde/
paraffin-embedded
tissue using
NB300-144.
Species: Hu, Mu, Rt
Applications: IHC-Fr, IHC-P, WB
Species: Hu
Applications: IHC-Fr, IHC-P, IP, RIA, WB
Species: Hu
Applications: FACS, ICC, IHC, IP, WB
MMP-13 Antibody
NB110-60992
MMP-2 Antibody
NB200-193
p53 Antibody
NB100-1746
Staining of
formalin fixed and
Paraffin embedded
human placenta tissue
using NB110-60992.
Species: Hu
Applications: IHC, WB
For research purposes only.
Not for use in humans.
Prices subject to change.
Staining of human
skin squamous
cell carcinoma using
NB100-1746.
Detection of MMP2 in
a paraffin-embedded
human neurofibroma
using NB200-193.
Species: Ch, Hu, Mu, Rt
Applications: ELISA, IHC-Fr, IHC-P, WB
Species: Hu
Applications: IHC
FAX: 303.730.1966 • WEB: www.novusbio.com
20
PKC alpha Antibody
NB110-57353
p63 Antibody
NB100-691
PSA Antibody
NB600-835
Staining of
formalin-fixed,
paraffin-embedded
human prostate
carcinoma using
NB600-835.
Staining of human
thyroid gland
carcinoma using
NB110-57353.
Staining of formalin
fixed paraffin
embedded human
skin using NB100-691.
Species: Hu, Mu, Rt
Applications: IF, IHC-P, IP, WB
Species: Hu, Mu, Rt
Applications: FACS, ICC, IHC, IP, WB
Specie
Species:
cies
i s: Hu
Hu
Applications: IHC-P, WB
SNCG Antibody
NB110-60497
Survivin Antibody
NB500-238
Survivin Antibody
NB500-201
Species: Hu
Applications: ELISA, IHC-Fr, IHC-P, WB
Telophase with
accumulation of
survivin in the midbodies of two
daughter cells.
Staining of ovary
carcinoma using
NB500-238.
Immunohistochemical
staining of
paraffin-embedded
human ovary
carcinoma using
NB110-60497.
Species: Hu, Mu, Rt
Applications: ICC, IF, IHC, IHC-P, WB
Species: Hu, Mu, Ca, Rt, Fe
Applications: IF, WB, IHC-P, IP, ICC.
Colorectal Cancer
Although only a quarter of diagnosed colorectal tumors
are malignant, this portion still accounts for 150,000
cases of colorectal cancer in the United states each
year, resulting in nearly 50,000 deaths. Nearly all
Bcl-2 Antibody
NB200-572
Caspase 7 Antibody
NB110-55664
CDX-2 Antibody
NB110-40734
Staining of FFPE
human ovarian
carcinoma
using NB110-40734.
Immunofluorescent
staining of HeLa cells
using NB110-55664.
Formalin-fixed,
paraffin-embedded
human tonsil stained
using NB 200-572.
Species: Hu, Mk
Applications: IHC-P, WB
Species: Hu
Applications: ICC, IHC, IP, WB
Species: Hu
Applications: IHC
CDX-2 Antibody
NB100-699
Cyclooxygenase-2 Antibody
NB100-689
Galectin-3 Antibody
NB300-538
Immunohistochemical
staining using
NB100-699.
Staining of formalin
fixed paraffin
embedded human
colon carcinoma using
NB100-689.
Staining of rat
olfactory bulb using
NB300-538.
Species: Hu
Applications: IHC
Species: Hu, Mu, Rt
Applications: IHC-Fr, IHC-P, IP, WB
S
Species:
i
Hu,
H Mu,
M Rt
Applications: ELISA, FACS, IF, IHC, IP, WB
Ki67 Antibody
NB500-170
Ki67 Antibody
NB600-1209
MMP-9 Antibody
NB110-57222
Staining of FFPE
human tonsil
using NB500-170.
Species: Hu, Mu, Po, Rt
Applications: ICC, IF, IHC-Fr, IHC-P
21
malignant colorectal tumors are adenocarcinomas,
although lymphomas, leiomyosarcomas, and carcinoids
can also occur in the colorectal region.
Staining of human
lymph node using
NB600-1209.
Species: Hu
Applications: IHC, IHC-Fr, WB
Immunohistochemical
staining of paraffinembedded human
lymphoma using
NB110-57222.
Species: Hu
Applications: FACS, ICC, IHC, WB
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MMP-9 Antibody
NB100-59029
MMP-9 Antibody
NB110-57223
Immunohistochemical
staining of paraffinembedded human
breast carcinoma using
NB110-57223.
MUC1 Antibody
NB120-15481
Staining of skin
granulation
tissue using
NB100-59029.
Staining of
breast carcinoma
using
NB120-15481.
Species: Hu
Applications: FACS, IHC, WB
Species: Hu
Applications: IHC-P
Species: Hu, Mu
Applications: IHC-P, WB
Osteopontin Antibody
NB600-1043
p63 Antibody
NB110-57309
PGP9.5 Antibody
NB600-1160
Staining of human
breast tumor cells
using NB600-1043.
Immunofluorescent
staining of A431 cells
using NB110-57309.
Staining of rat
abdominal tissue
using NB600-1160.
Species: Ca, Hu, Po
Applications: IHC, WB
Species: Hu
Applications: ICC, IP, WB
Species: Hu, Rt
Applications: ELISA, IHC-P, WB
SMAD4 Antibody
NB110-57582
STAT3 Antibody
NB110-57596
Species: Hu, Mu, Rt
Applications: FACS, ICC, IHC, IP, WB
S
Species:
i
Hu
H
Applications: ICC, IHC, IP, WB
Telomerase Antibody
NB600-476
Immunofluorescence
microscopy of Saos-2
cells transduced with
a retroviral vector
expressing hTERT and
GFP rom an internal
ribosomal entry site.
Species: Hu
Applications: IF, IHC, IP, WB
Telomerase Antibody
NB100-317
TEM-8 Antibody
NB110-17405
VEGF-D Antibody
NB110-60973
Immunohistochemical
staining of paraffinembedded human
lung carcinoma using
NB110-57582.
Staining of normal
pancreas using
NB100-317.
Species: Hu
Applications: FACS, IF, WB
Immunohistochemical
staining of paraffinembedded lung
squamous carcinoma
using NB110-57596.
Immunohistochemical staining of human
brain tissue using
NB110-17405.
Species: Hu, Mu, Rt
Applications: IHC, WB
Formalin fixed and
Paraffin embedded
human placenta tissue
using NB110-60973.
Species: Hu
Applications: IHC, WB
Lung Cancer
Lung cancer is the most common non-skin cancer, with
an estimated 215,000 new cases diagnosed in 2008
in the United States. Additionally, more than 160,000
people will die in the United States from lung cancer in
2008, making lung cancer the leading cause of cancer
MUC16 Antibody
NB200-562
Staining of
human lung tissue
(alveolocytes
type II) using
NB200-562.
Species: Hu
Applications: ELISA, IHC-P, WB
For research purposes only.
Not for use in humans.
Prices subject to change.
deaths. While most cases of lung cancer are related to
smoking, there are other risk factors including genetics,
family history of lung cancer and exposure to chemicals and pollution.
Calcitonin Antibody
NB110-55646
Immunohistochemical
staining of paraffinembedded human
thyroid using
NB110-55646.
CEA Antibody
NB120-15987
Species: Hu, Mu, Rt
Applications: IHC
Species: Hu
Applications: ELISA, IHC-P
Staining of formalin
fixed paraffin
embedded
human colon
carcinoma using
NB120-15987.
FAX: 303.730.1966 • WEB: www.novusbio.com
hTERT Antibody
NB100-317
CEA Antibody
NB120-15287
COX-2 Antibody
NB100-689
Staining of pancreatic
carcinoma using
NB100-317.
Staining of
formalin fixed
paraffin embedded
human breast using
NB120-15287.
Staining of formalin
fixed paraffin embedded human
colon carcinoma using
NB100-689.
Species: Hu, Mu, Rt
Applications: IHC-Fr, IHC-P, IP, WB
S
Species:
i
Hu
H
Applications: IHC
Species: Hu
Applications: FACS, IHC-P, IF, WB
Ki67 Antibody
NB110-57147
Ki67 Antibody
NB600-1252
MAP-2 Antibody
NB110-58369
MAP-2-positive
cultured neurons
(green) from an e13.5
mouse brain. Nuclei
are blue.
Staining of formalinfixed, paraffinembedded human
tonsil using
NB600-1252.
Immunohistochemical
staining of paraffinembedded Human
tonsil using
NB110-57147.
Species: Hu, Mu, Rt
Applications: IHC
Species: Hu, Rt
Applications:IHC-Fr, IHC-P
Species: Mu
Applications: ICC, IHC, IHC-P, WB
MAP-2 Antibody
NB300-213
NSE Antibody
NB110-58870
NSE Antibody
NB100-1606
Rat neurons stained
with anti-MAP2 (NB
300-213) [green]
and anti-GFAP (NB
300-142) [red].
Dissociated cell
cultures of neonatal
mouse brains, showing
NSE-2 (green staining)
in neurons.
Staining of
HEL293 cells using
NB110-58870.
Species: Bv, Hu, Mu, Rt
Applications: IF, WB
Species: Hu, Rt
Applications: IF, WB
Species: Mu
Applications: ICC, IHC
Osteopontin Antibody
NB600-1043
Staining of human
breast tumor
using NB600-1043.
Osteopontin Antibody
NB100-1883
Staining of
paraffin embedded
human tonsil using
NB100-1883.
p63 Antibody
NB100-691
Species: Ca, Hu, Po
Applications: IHC, WB
Species: Hu
Applications: ELISA, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: IF, IHC-P, IP, WB
p63 Antibody
NB110-57309
PGP9.5 Antibody
NB300-675
Smac Antibody
NB110-56936
Staining of A431 cells
using NB110-57309.
Staining of formalin
fixed paraffin
embedded
human skin using
NB100-691.
Immunohistochemical
staining of paraffinembedded human
skin cancer tissue
using NB110-56936.
Staining of
human
brain using
NB300-675.
Species: Hu
Applications: ICC, IP, WB
Species: Mu
Applications: IHC, WB
Species: Hu, Rt
Applications: FACS, ICC, IHC, IP, WB
Survivin Antibody
NB500-237
Telomerase Antibody
NB600-476
UCHL1 Antibody
NB300-676
Staining of lung
carcinoma using
NB500-237.
Species: Hu
Applications: IF, IHC, WB
Staining of
human
brain using
NB300-676.
Immunofluorescence
staining of Saos-2
cells transduced with
a retroviral vector
expressing hTERT
using NB600-476.
S
Species:
i
Hu
H
Applications: IF, IHC, IP, WB
Species: Mu
Applications: IHC, WB
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Prostate Cancer
For men in the United States, prostate cancer is the
most common non-skin cancer and is the second most
deadly cancer. With over $8 billion spent annually in
the United States on prostate cancer research, prostate
cancer diagnoses and deaths have declined in recent
years after rising in the 1980s because of new detection
techniques. Nearly 1 in 6 men will be diagnosed with
prostate cancer at some point in their lives.
Caveolin-1 Antibody
NB100-615
Bcl-2 Antibody
NB110-55551
Staining of EaHy926
endothelial cell line
using NB100-615.
Immunohistochemical
staining of paraffinembedded human
breast carcinoma using
NB110-55551.
Caveolin-1 Antibody
NB110-39015
Staining of
respiratory epithelium
and alveole using
NB110-39015.
Species: Hu, Mu
Applications: FACS, ICC, IHC, IP, WB
Species: Hu, Mu, Rt
Applications: IF, IP, WB
Species: Hu
Applications: IHC
Caveolin-1 Antibody
NB110-39016
DPP4 Antibody
NB100-58756
DPP4 Antibody
NB100-59021
Staining of respiratory
epithelium, bronchial
smooth muscle, and
alveoli using NB11039016.
Staining of placenta
using NB100-58756.
Staining of placenta
using NB100-59021.
Species: Hu
Applications: IHC
Species: Hu
Applications: IHC-P
Species: Hu
Applications: IHC-P
E-cadherin Antibody
NB110-56937
Immunohistochemical
staining of paraffinembedded human
hepatocellular carcinoma using NB11056937.
HGF Antibody
NB110-57200
Ki67 Antibody
NB600-1209
Species: Hu, Mu
Applications: ICC, IHC, IP, WB
Species: Hu
Applications: ICC, IHC, WB
Species: Hu
Applications: IHC, IHC-Fr, WB
LDH Antibody
NB110-57161
MCM7 Antibody
NB110-57188
PCNA Antibody
NB500-106
Immunohistochemical
staining of paraffinembedded human
breast carcinoma
using NB110-57200.
Immunohistochemical
staining of paraffinembedded human
testis carcinoma using
NB110-57161.
Staining of human
lymph node using
NB600-1209.
Immunohistochemical
staining of paraffinembedded human
lung tissue using
NB110-57188.
Immunohistochemical
staining of paraffinembedded human
colon carcinoma,
using NB500-106.
Species: Hu
Applications: FACS, IHC, WB
Species: Hu, Mu, Rt
Applications: FACS, ICC, IHC, IP, WB
Species: Ch, Dr, Hu, Mu, Rt, Ye
Applications: IHC, IP, WB
PSA Antibody
NB110-59960
PSA Antibody
NB600-835
S100A6 Antibody
NB100-1765
Immmunohistochemical
staining of paraffinembedded human
prostate carcinoma
using NB110-59960.
Species: Hu
Applications: IHC-P, WB
For research purposes only.
Not for use in humans.
Prices subject to change.
Immunohistochemical
staining of paraffin-embedded brain glioma
tissue using NB1001765.
Staining of formalinfixed, paraffinembedded human
prostate carcinoma
using NB600-835.
Species: Hu
Applications: IHC-P, WB
Species: Hu
Applications: ELISA, IHC, WB
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