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Name: . Biology I Cancer Webquest 12.05.07 Go to www.asdk12.org Follow the links to Mr. Mason’s Biology page, go to the “links” section. Click on the link for “Cancer – How Cancer Grows” 1. How many Americans are expected to die from cancer this year? 2. Click on “How Cancer Grows”. What type of cancer will we be looking at? 3. How many cells do you have in your body? 4. What is a DNA mutation? How can one happen (2 ways)?? These are different answers – read carefully here! 5. From your notes from yesterday, what kind of gene is mutated when a cell divides even though it doesn’t need to? 6. The website talks about a second and third mutation – what genes is it referring to? (hint: the brakes and the gas tank) 7. Epithelial tissue is a thin layer of proteins and cells that cover many internal organs. What is the problem when cancer cells break through this barrier? 8. How big does a tumor usually have to be to be detected? 9. What are the two problems that come with angiogenesis? (answers on two separate slides) 10. What is it specifically that actually leads to death from cancer? Go back to my links page and click on “Cancer – Inside Cancer” Click on “Hallmarks of Cancer” – use the numbers at the bottom to move through the slides. 11. What percentage of cancers are inherited? What is the primary cause of most mutations that lead to cancer? 12. What is produced as a result of a DNA mutation? 13. Click on “Growing Uncontrollably”. According to the bald guy, what two things must cancer cells learn how to do? 14. Click on “Evading Death”. We already know that apoptosis is cell suicide. What does the cell actually do to itself to carry out apoptosis? This is a little bit confusing – ask Mr. Mason to come over and explain if you’re not clear. 15. Click on “Processing Nutrients”. Why specifically must cancerous tumors undergo angiogenesis? 16. Click on “Becoming Immortal”. Where are telomeres found? 17. What is the process that’s going on in the lower right-hand corner of slide #5? The answer isn’t there – you figure it out! 18. When are the two times that telomerase is normally expressed? 19. How does telomerase help cancer cells? 20. Click on “Invading Tissues”. Remind me again…what is metastasis? Click on “Causes and Prevention 21. On #3 of the Overview, look at the map of worldwide cancer rates. Which country has the highest lung cancer rate in the world for men? Which country is highest for women?? Surprised? 22. What countries have the highest rates of breast cancer? About how many women out of 1,000 will get breast cancer every year? 23. Stomach cancer is a weird one. What do we think might be the common link between countries with a high rate of this cancer? 24. Click on “Smoking” and then “Killers in Smoke”. How many carcinogens are there in cigarette smoke? 25. What are the cilia in your lungs supposed to do to help you? 26. What does smoke do to your cilia? What is the effect?? EXTRA CREDIT!!! Finished all of that? Want some extra credit? Spend some time looking through this site. Find some information that interests you, whether it is about causes of cancer, different types, treatment, or whatever. Your task is to teach me something new! Jot down notes on the back and share what you have found. Enjoy!