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Bellwork Quietly have a set and get out your yeast labs Answer the following questions: What is chromatin? What is the cause of Down syndrome? What are centrioles? Chapter 8: Cell Reproduction 8.1 Chromosomes 8.1 Chromosomes https://www.youtube.com/watch?v=xUrlreMaUrs 8.1 Chromosomes Objectives: I will be able to: Describe the structure of a chromosome Identify the differences in structure between prokaryotic chromosomes and eukaryotic chromosomes Compare the numbers of chromosomes in different species Explain the differences between sex chromosomes and autosomes Distinguish between diploid and haploid cells Chromosomes Chromosomes – rod-shaped structures made of DNA and proteins How Chromosomes are Formed starts with DNA DNA – genetic information of the cell How Chromosomes are Formed DNA wrapped around histones Histone – protein that supports shape of chromosomes How Chromosomes are Formed DNA Who wrapped around histones creates chromatin remembers what chromatin is? (check animal cell graphic organizer) How Chromosomes are Formed DNA wrapped around histones creates chromatin Who remembers what chromatin is? (check animal cell graphic organizer) Chromatin – loosely coiled DNA and histones How Chromosomes are Formed During cell reproduction, chromatin condenses to form tightly wound chromosomes Chromosomes – tightly packed bodies of DNA How Chromosomes are Formed Why must the DNA be so tightly packed? How Chromosomes are Formed DNA (wrapped around histones) → chromatin → chromosome How Chromosomes are Formed Chromosome Structure Chromosome made of 2 chromatids Chromatid –2 identical halves of a chromosome Chromosome Structure Centromere – where the chromatids are attached Prokaryote Chromosome Review: what are the differences between prokaryotes and eukaryotes? Prokaryote Chromosome Review: what are the differences between prokaryotes and eukaryotes? Prokaryotes do NOT have a membrane-bound nucleus nor membrane-bound organelles!!!!!!!!!!!!!!!!!!! Prokaryote Chromosome usually has only 1 chromosome Chromosome has circular DNA Chromosome Numbers Different organisms have different numbers of chromosomes Chromosome Numbers Different organisms have different numbers of chromosomes Organism Chromosome Number Fruit Fly 8 Pea 14 Human 46 Chimpanzee 48 Goldfish 94 Adder’s Tongue Fern 1,262 Chromosome Numbers Types of Chromosome Sex chromosomes – determine sex of an organism X and Y in humans XX = female XY = males Humans have 2 Autosomes humans – all other chromosomes have 44 Types of Chromosome Autosomes Homologous chromosomes - 2 identical copies of each autosomes present in all cells One copy from each parent Karyotype What is a karyotype? Karyotype What is a karyotype? Photomicrograph What of chromosomes you made yesterday by cutting and gluing!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! Karyotype What is a karyotype? Photomicrograph of chromosomes What you made yesterday by cutting and gluing!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! 22 2 pairs of homologous chromosomes (44 total) sex chromosomes Karyotype (female or male) Karyotype (what’s wrong with this picture?) Diploid Cells Diploid all cells – cells with 2 sets of chromosomes human cells (except egg and sperm cells) are diploid Diploid Cell Abbreviation Abbreviated In as 2n humans 2n = 46 chromosomes Haploid Cell Haploid Only cells – contain only 1 set of chromosomes sperm and egg cells in humans Haploid Cell Abbreviation Abbreviated In as n humans n = 23 chromosomes Diploid vs. Haploid Cells 8.2 Cell Division Sunda Colugo 8.2 Cell Division Learning Targets I will be able to: Describe the events of cell division in prokaryotes Summarize Describe the events of interphase the stages of mitosis Compare plant cells cytokinesis in animal cells with cytokinesis in 8.2 Cell Division https://www.youtube.com/watch?v=AhgRhXl7w_g Prokaryote Cell Division Binary fission – process of cell division used by prokaryotes Review: what shape is prokaryotic DNA? Prokaryote Cell Division Binary fission – process of cell division used by prokaryotes Review: what shape is prokaryotic DNA? CIRCULAR !!!!!!!!!! Prokaryote Cell Division Eukaryote Cell Division 2 types 1. Mitosis – 1 cell divides into 2 cells with same genetic material as parent cell 2. Meiosis – 1 cell divides into 2 cells; each has half the number of chromosomes (produces gametes) Cell Cycle Interphase Interphase Cells – time when cells are NOT dividing spends most of its time in interphase 3 Stages of Interphase 1. G1 Phase – cells grow 2. S phase – DNA copied 3. G2 Phase – preparation for cell division Optional 4th Stage of Interphase G0 Phase – cells grow Resting phase 4 Stages of Mitosis Review: what is mitosis? 4 Stages of Mitosis Review: 1 what is mitosis? cell divides into 2 cells with same genetic material as parent cell 4 Stages of Mitosis Review: What is the difference between chromatin and chromosomes? 4 Stages of Mitosis Review: What is the difference between chromatin and chromosomes? Chromatin condenses to become chromosomes! 4 Stages of Mitosis 1. Prophase DNA shortens and condenses into chromosomes Nuclear membrane and nucleolus disappear Centrioles Spindle appear fibers attach to centromere 4 Stages of Mitosis 2. Metaphase Spindle fibers move chromosome to middle of cell “metaphase = middle” 4 Stages of Mitosis 3. Anaphase Chromatids separate at centromere and move to opposite poles of cell Each forms own chromosome 4 Stages of Mitosis 4. Telophase Spindle fibers disappear Nuclear envelope and nucleolus reform Cytoplasm divide begins to Cytokinesis Cleavage furrow – where cell membrane pinches in to separate 2 new cells Occurs in animals Cell plate – forms in plants Precursor to cell wall Cytokinesis Prophase Metaphase Anaphase Telophase Cytokinesis Please Make A Terrific Cake Uncontrolled Mitosis Results in cells that do NOT stop dividing Eventually cancer become tumors 8.3 Meiosis 8.3 Meiosis (okapi) 8.3 Meiosis Objectives I will be able to: Compare the end products of meiosis with the end products of mitosis Summarize the events of meiosis I Explain crossing-over and how it contributes to the production of unique individuals Summarize the events of meiosis II Compare spermatogenesis and oogenesis Define sexual reproduction Meiosis Meiosis – cell division resulting in haploid cells Produces gametes (sperm and egg cells) Meiosis has 2 stages 1. Meiosis I 2. Meiosos II Meiosis I Called Has reduction division 4 stages………guess what they are Meiosis I Has 4 phases………guess what they are 1. Prophase I 2. Metaphase I 3. Anaphase I 4. Telophase I and Cytokinesis I Prophase I DNA is copied here DNA coils tightly into chromosome Spindle fibers appear Nuclear membrane and nucleolus disappear Synapsis – when homologous chromosomes pair up Tetrad – pair of homologous chromosomes Early Prophase I Prophase I Prophase I Crossing-over occurs here Crossing-over – parts of chromatids break off and attach to neighbor chromatids Allows for the exchange of genetic material between chromosomes from mother and father Genetic created recombination – new mixture of genetic material Prophase I Metaphase I Tetrads line up in the middle of the cell Anaphase I Each homologous chromosome moves to opposite poles of cell Independent assortment – random separation of maternal and paternal chromosomes Prophase I and Cytokinesis I 2 new cells produced with half the number of chromosomes (haploid) (n) Meiosis II DNA Cells is NOT copied undergo division similar to mitosis Prophase II Spindle fibers form Metaphase II Chromosomes are aligned along the middle of the cell Anaphase II Chromatids separate towards opposite ends of cell Telophase II Nuclear reforms envelope Cytokinesis II Cytoplasm 4 new cells splits forming Development of Gametes Meiosis results in 4 haploid gametes Gamete – haploid reproductive cell Sperm Egg in human males in human females Males 4 spermatids form through meiosis Spermatids develop into mature sperm cells through spermatogenesis Females Oogenesis of ova Ova 1 – production – mature egg cells ovum produced during meiosis Females Oogenesis of ova Ova – production – mature egg cells 1 ovum produced during meiosis 3 polar bodies also produced Ovum retains most of the cytoplasm Why? Sexual Reproduction Production of offspring through fusion of sperm and egg Offspring are genetically different from parents Allows species to adapt quickly to new conditions Asexual Reproduction Offspring come from a single organism Binary fission and mitosis are examples