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The Human Body: From Food to Fuel BIOL 103, Chapter 4 (Part 1) Today’s Topics • • • • • Taste and Smell GI Tract Digestion and Absorption Assisting Organs Circulation of Nutrients Taste and Smell: The Beginnings of our Food Experience • Sight, smell, thought, taste, and sound – Can trigger a set of responses that prepare the digestive tract to receive food The Gastrointestinal (GI) Tract • Organization – ____________________ • mouth, esophagus, stomach, small intestine, large intestine, rectum – ____________________ • Salivary glands, liver, gallbladder, and pancreas Organization of the GI Tract • Functions: – __________________(the receipt and softening of food) – __________________ of ingested food – __________________ of digestive enzymes, acid, mucus, and bile – __________________ of end products of digestion – __________________ of undigested material – __________________ of waste material Organization of the GI Tract • Structural organization of the GI tract – ____________________ (innermost layer) • Glands and absorptive cells – ____________________ ______________________ • Mix and move the food – _____________________: valve that controls the movement of food material so that it travels through the GI tract in only one direction. Overview of Digestion • Mouth – Chewing _______________________________ – Saliva _________________________________ • Down the GI tract: – Physical movement • __________________________: waves of muscular contraction that helps push food down the GI tract • __________________________: a periodic muscle contractions in the small intestine that move the content forward and backward, Overview of Digestion • Chemical breakdown: – __________________________ (a mass of partially digested food + digestive juices moving from stomach into small intestine) • _______________________: are proteins that catalyze (speed up) reactions but are not altered in the process. – Examples: amylase, lipase, etc. • Other secretions: Overview of Digestion Overview of Absorption • 3 Main processes allow nutrients to be absorbed from GI tract blood/circulation – _____________________: movement of molecules through cell membrane from ___________________ _____________________________________________ – _____________________: movement of molecules through cell membrane from ___________________ _____________________________________________ – _____________________: movement of molecules through cell membrane ________________________ _____________________________________________ _ Overview of Absorption Assisting Organs • Salivary glands – ______________________________ – Supply enzymes • Liver – _______________________________________ – “Detox center:” _________________________ – “Chemical factory”: ______________________ • Produce blood proteins, cholesterol, sugar – ____________________: stores hormones, cholesterol, minerals, sugar, etc. • Gallbladder – ____________________________________ – Bile’s Enterohepatic circulation: • _______________________________________ _________________________________________ • Pancreas – ____________________________________ – Secretes hormones _________________________ Putting It All Together: Digestion and Absorption • Mouth – Enzymes • ____________________________________ • ____________________________________ – Saliva • Moistens food for swallowing forms into bolus • Esophagus – Transports food to stomach – ___________________________________________ • “Heartburn” Putting It All Together: Digestion and Absorption • Stomach Enzymes: – Hydrochloric acid/gastric acid 1. ________________________ 2. ________________________ 1. 2. breaks down 3D structure of protein _________________________________________________________________ – Pepsin: _____________________________________ – Gastric lipase: some fat digestion – Gastrin (hormone) stimulates gastric secretion and movement – Intrinsic factor _______________________________ Putting It All Together: Digestion and Absorption • Small intestine (~10ft) – _____________________ – Sections of small intestine: • _____________________ • _____________________ • _____________________ – Nutrient digestion • Bicarbonate ___________ _______________________ • Pancreatic and intestinal enzymes – ___________________ – ___________________ – ___________________ • Vitamins, minerals, cholesterol are not digested and generally absorbed unchanged. Putting It All Together: Digestion and Absorption • Small intestine – Completes absorption: • _________________________________ ___________________________________ – 600x fold increase/tennis court! • Most nutrients absorbed here • Fat-soluble nutrients ______________ ___________________________________ • Water-soluble nutrients ___________ Putting It All Together: Digestion and Absorption • Large Intestine – Ileocecal valve – Sections • • • • _____________________ _____________________ _____________________ _____________________ – Digestion • Peristaltic movement is slow, taking 18-24 hours for material to travel • Some bacterial activity Example: _____________________ Beans, Beans, Beans! • Beans are made up of oligosaccharides (e.g. raffinose and stachyose), a component of fiber. • They are ignored until they are met by 700+ species of bacteria in your large intestine. – _________________________ _____________________ _________________ Putting It All Together: Digestion and Absorption • Large Intestine: – Absorption • ___________________ • ___________________ • ___________________ – _____________ at anal sphincter • Feces: 60% solid (bacteria, dietary fiber, digestive secretions), 40% water Circulation of Nutrients • Vascular system: veins and arteries – ____________________ ______________________ ______________________ ______________________ ______________________ – Removes wastes • ____________________ • ____________________ Circulation of Nutrients • Lymphatic system: vessels that drain lymph (clear fluid formed in the spaces between cells) 1. Fat soluble-vitamins are absorbed into lymph vessels in the intestine. 2. _______________________________________ __________________________________________ – Clean-up: proteins and large particulate matter in tissue spaces lymphatic system removed Circulation of Nutrients • Excretion and Elimination – Lungs • Excrete __________________________________ – _________________________________________ • Excrete digestive wastes – Urine: urea + salts + water • Maintain water and ion balance