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Running head: INTRAOSSEOUS VASCULAR ACCESS Use of Intraosseous Vascular Access in the Adult Population Stacey Swartzendruber Ferris State University Swartzendruber 1 INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 2 Abstract The need for intraosseous (IO) devices to be stocked on crash carts throughout the hospital has been of recent debate between the emergency room staff and the general medical and surgical staff. Concerns have been identified and research pertaining to those concerns is described below and relate to the amount of time it takes to place an IO. Also discussed is the comparison of the pharmacokinetics between morphine sulfate administered intravenously and intraosseously. INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 3 Intraosseous Vascular Access in the Adult Population The use of intraosseous vascular access in the adult population has been of recent discussion during meetings at the hospital where I work. Currently, the emergency department will place an intraosseous cannula in an adult patient who is in critical condition where peripheral intravenous access is inaccessible at that time. These devices are not stocked on crash carts used for emergent situations throughout the hospital. During an adult emergency, both the emergency room physician and one emergency room nurse respond to the emergency. They use the crash cart from the specific floor to obtain supplies and medication that will be used for that event. In the event that the patient does not have intravenous access, staff relies on the stock of peripheral intravenous catheters and central venous catheters within their crash carts to obtain vascular access with. Requests from the emergency department staff to stock intraosseous needles and insertion devices on crash carts throughout the hospital have been met with some resistance from the general medical and surgical staff unfamiliar with this technique. Reasons against stocking hospital-wide have varied. Some of the most frequent comments I have heard while speaking to people about this topic were: A central line would be more beneficial to the patient because labs could be taken from the patient once resuscitation is over and invasive monitoring could be performed through a central line. The time it takes for medication to reach circulation must be slower with use of intraosseous needles versus a central line. INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 4 Drilling into the bone of a patient must be difficult and too technical for a nurse to be performing. While concerns from the staff may at first seem reasonable, research is proving otherwise. Below are three research articles pertaining to the use of intraosseous insertion for critical patients in need of vascular access. Each article addresses the common questions and concerns staff currently has. Research Article One Research Findings The first research article compares two common approaches to obtaining vascular access in a patient where peripheral intravenous (IV) cannulation is unattainable during critical medical conditions (Leidel et al, 2009). The two approaches are central venous catheterization (CVC) and intraosseous vascular access (IO). The study involved patients 18 and older who were seen at a level 1 trauma center, lacking IV access upon arrival (Leidel et al, 2009). The trauma team attempted peripheral IV access three times before proceeding with the study. After three unsuccessful IV attempts, an anesthesiologist began placement of a CVC at the same time a surgeon placed an IO (Leidel et al, 2009). The time it took to perform each technique (including time preparing for the procedure), the ability to properly place the devices on the first attempt, as well as the total number of attempts it took to properly place the devices were recorded (Leidel et al, 2009). There were a total of ten patients that were involved in this study (Leidel et al, 2009). The results were as follows: the success rate for IO was 90% compared to CVC (60%) on first attempt. Time placement was quicker for IO placement than for CVC placement (2.3 minutes versus 9.9 minutes, respectively) (Leidel et al, 2009). INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 5 Critique of Research A limitation of this study was the population size used (ten patients). Even though results were consistent, it would be beneficial to see this study applied toward a larger patient number. Implications for Practice This research validates the use of intraosseous cannulation when peripheral intravenous access is unattainable. In regards to my own practice, we have been using IO as a first route of vascular access in critically ill patients who lack IV access. After resuscitation or stabilization, the patient then receives a central venous catheter under a more controlled setting. This study reinforces that this nursing task is appropriate in these situations. This study also enables me to stress the importance of the need for IO availability on crash carts, as obtaining IV access during cardiac arrest can be difficult and time consuming. The IO can provide that vascular access quicker than a CVC could (Leidel et al, 2009). Research Article Two The next research article focused on a specific brand of intraosseous insertion devices, the EZ-IO which is one of the two that is carried in the department I work in (Su Yin, Oh, Chen, Yong, & Ong, 2009). Again…as above..regarding title and authors Research Findings This study was performed to determine whether IO cannulation was an “alternative to vascular access in the emergency department” (Su Yin, Oh, Chen, Yong, & Ong, 2009, pp. 155). The study lasted from March of 2006 until July of 2007 and studied the use of IO access in 24 patients (Su Yin, Oh, Chen, Yong, & Ong, 2009). The patient population was patients ages 16 and older who came to the emergency department critically injured or ill and did not have achievable peripheral IV access (Su Yin, Oh, Chen, Yong, & Ong, 2009). Other criteria were INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 6 present that qualified them as a critical patient (due to mental status, respiratory status, blood pressure problems, or presence of cardiac arrest) (Su Yin, Oh, Chen, Yong, & Ong, 2009). Success rates and number of attempts were recorded, as well as site placement. Flow rates of the IO fluids were monitored and recorded, as well as any complications encountered (Su Yin, Oh, Chen, Yong, & Ong, 2009). The findings indicate that Io use by way of EZ-IO is an appropriate alternative to IV access for patient resuscitation, especially when pressure bags were used to assist in faster fluid administration (Su Yin, Oh, Chen, Yong, & Ong, 2009). Critique of Research This research also has a limitation of the number of patients. A larger patient population would be useful to ensure consistent results. This research was done at a large emergency department and its authors work within that department. A special note was included, stating, “no cast sponsorship was used for this study” although EZ-IOs were provided by the maker of them (Su Yin, Oh, Chen, Yong, & Ong, 2009, pp. 159). Implications for Practice This research article once again supports the use of IO access when IV access is unattainable during the immediate resuscitation period. It applies toward my clinical practice because we use the EZ-IO as one of our IO placement devices. Research Article Three The last article looks at another question raised by other staff members at my facility: is the administration of medications through an IO the same as through an IV? (Von Hoff, Kuhn, Burris, & Miller, 2008). As above Research Findings INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 7 This article describes research that aimed to compare the pharmacokinetics of IO and IV medication. This study used morphine sulfate as the drug for comparison (Von Hoff, Kuhn, Burris, & Miller, 2008). Cancer patients at eight clinical sites who were not able to maintain IV access were chosen as the patient population. They had implanted IO devices placed as well as an IV. A dose of morphine sulfate was given to the patient via one site (either IO or IV) and blood draws were obtained prior to administration, and at defined times periods postadministration. The patient then received the same dose of morphine sulfate 24 hours later via the other vascular access route (if they first received it through IO, they would then receive it IV 24 hours later), and again had blood draws in the same manner (Von Hoff, Kuhn, Burris, & Miller, 2008). Results showed “no significant differences between the IO and IV route on plasma morphine concentration vs. sampling data” (Von Hoff, D., et al, 2008, pp. 35) . The study also states “ the IO and IV delivery results for morphine sulfate were essentially equivalent” (Von Hoff, D., et al, 2008, pp. 35). Critique of Research This research was done at more than one clinical site across the United States (Von Hoff, D., et al, 2008 ). The Institutional Review Boards of each institution approved this study (Von Hoff, D., et al, 2008). While the results for morphine sulfate showed that both routes were equivalent (Von Hoff, D., et al, 2008), it does not mean that it would be the same for every drug. Implications for Practice This research does not change our practice in the emergency department, but again allows me to provide other staff members, who are showing some resistance to the efficacy of this route of medication administration, information supporting its use. INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 8 Critical Reflection Each of these research articles relate to a nursing theory by Afaf Ibrahim Meleis: the transition theory (Alligood & Tomey, 2010). Again..this should read, Alligood & Tomey, 2010….This nursing theory describes the levels of transition that a person goes through: awareness, engagement, change and difference, time span, and critical points and events (Alligood & Tomey, 2010). Using this theory, it is not a patient that is going through the transition, but it is the hospital and staff that are going through transition. Awareness of a possible need for change in routine has been addressed. Staff has become engaged in the discussion surrounding the use of intraosseous needles and why it is necessary to keep them stocked on the crash carts for use during an emergency. Changes have been identified, and it is in this part of transition where the difficulty to move forward lies. It would be a change in nursing practice for some of the floor nurses to become familiar with insertion and maintenance of an intraosseous device. Competencies would need to be developed and education implemented. The possibility of changes in cost due to stocking of an infrequently used supply is present. The remaining stages of transition in regards to this nursing topic will not be completed until a decision has been made whether to accept this change or stay with current practice. If there is a positive movement forward, a time span for completion of this transition to the use of intraosseous needles throughout the hospital needs to be identified. Critical points would be when the staff has begun using this device and feedback regarding it occurs. The staff may participate more in the delivery of this care and begin teaching it to new employees and recognize the positive change that has occurred. INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 9 While it may take a while for staff to agree that there is a need to stock intraosseous insertion devices on crash carts throughout the hospital, I strongly feel that this discussion should continue. While I can understand some of the concerns of other staff members, I feel that a lack of education regarding the benefits of these devices is the biggest barrier to moving forward with this change. The research is proving that it is beneficial to the patient and is less time consuming to use intraosseous devices (Leidel et al, 2009). I will continue to research this topic and provide evidence that these devices are truly a benefit to the patient, and are worth stocking throughout the hospital. INTRAOSSEOUS VASCUALAR ACCESS Swartzendruber 10 References Alligood, M., & Tomey, A. (2010). Afaf Ibrahim Meleis: Transition theory. Nursing Theorists and Their Work (pp. 416-433). Maryland Heights, MO: Elsevier. Leidel, B., Kirchhoff, C., Bogner, V., Stegmaier, J., Mutschler, W., Kanz, K., & Braunstein, V. (2009). Is the intraosseous access route fast and efficacious compared to conventional central venous catheterization in adult patients under resuscitation in the emergency department? A prospective observational pilot study. Patient Safety in Surgery, 3, 24. doi:10.1186/1754-9493-3-24 Von Hoff, D., Kuhn, J., Burris, H.,& Miller, L. (2008). Does intraosseous equal intravenous? A pharmacokinetic study. American Journal of Emergency Medicine, 26, 31-38. doi:10.1016/j.ajem.2007.03.024 Su Yin, A., Oh, J., Chen, Y., Yong, D.,& Ong, M. (2009). Intraosseous vascular access in adults using the EZ-IO in an emergency department. International Journal of Emergency Medicine, 2, 155-160. doi 10.1007/s12245-009-0116-9