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FASEB Hematologic Malignancies Conference
July 23-28, 2017
Saxtons River, Vermont
Organizers:
Iannis Aifantis, Ph.D.
New York University
New York, NY
Kimberly Stegmaier, M.D.
Dana-Farber Cancer institute and Boston Children’s Hospital
Boston, MA
Sunday, July, 23, 2017
4:00 p.m. – 9:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 8:00 p.m.
8:00 p.m. – 9:30 p.m.
Conference Registration
Welcome Reception
DINNER
Opening Keynote Speaker
Targeted Therapies and Leukemia
James Bradner
Monday, July, 24, 2017
7:30 a.m. – 1:00 p.m.,
4:00 p.m. – 6:00 p.m.
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
27 January 2017
Conference Registration
BREAKFAST
Conference Registration
Regulation of Transcription and
Signaling in Hematological
Malignancies: Part I
Adolfo Ferrando (Chair)
Application of Functional and
Cancer Genomics to Dissect
Mechanisms of Leukemogenesis
Scott Lowe
Aberrant Transcription in AML
Ruud Delwel
New Discoveries in Childhood B-ALL
Shai Izraeli
Transcriptional Dysregulation in TALL
Adolfo Ferrando
10:00 a.m. – 10:15 a.m.
12:00 p.m. – 1:00 p.m.
(at the end, the session will include
short presentations selected from
abstracts, aka “poster teasers”)
FASEB Sponsored Coffee Break
LUNCH
1:00 p.m. – 2:30 p.m.
Career Development Workshop
2:30 p.m. – 4:00 p.m.
4:00 p.m. – 6:00 p.m.
Finding a Job/ Starting an Academic Ross Levine
Lab
Free time
Poster Session
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:00 p.m.
Conference Registration
DINNER
Regulation of Transcription and
Signaling in Hematological
Malignancies: Part II
Michelle Kelliher (Chair)
Targeting Dysfunctional Gene
Expression Control in Leukemia
Christopher Vakoc
Mechanisms of T-ALL
Leukemogenesis
Michelle Kelliher
Mechanisms of T-ALL
Leukemogenesis
Thomas Look
Aberrant Splicing in Hematopoietic
Malignancies
Omar Abdel-Wahab
Tuesday, July, 25, 2017
7:30 a.m. – 1:00 p.m.,
4:00 p.m. – 6:00 p.m.
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
Conference Registration
BREAKFAST
Conference Registration
Targets, Drugs and Mechanisms of
Resistance: Part I
Mechanisms of Resistance to
Signaling Inhibitors in Leukemia
Kevin Shannon
Targeting Transcription Factorfusion Driven Leukemia
Jolanta Grembecka
In Vivo Functional Genomic
27 January 2017
Tanja Gruber (Chair)
Screening to Drug Identify
Resistance Mechanisms
New Targets in High-risk Pediatric
Leukemias
10:00 a.m. – 10:30 a.m.
12:00 p.m. – 1:00 p.m.
1:00 p.m. – 2:30 p.m.
1:00 p.m. – 4:00 p.m.
4:00 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:00 p.m.
New Approaches to Measure Drug
Response
FASEB Sponsored Coffee Break and
*Group Photo
LUNCH
Michael Hemann
Tanja Gruber
David Weinstock
Meet the Experts Session
Work-life Balance
Free time
Poster Session
Conference Registration
DINNER
Targets, Drugs and Mechanisms of
Resistance: Part II
Jonathan Licht, Kimberly Stegmaier &
Jane Skok
Functional Genomic Screening
Approaches to Identify New Targets
in Leukemia
Johannes Zuber
Targeted Approaches to Childhood
Leukemia
Mignon Loh
Drugging the "Undruggable"
John Bushweller
Dissecting the Underpinnings of
MDS: Molecular Origins and
Therapeutic Response
Benjamin Ebert
Mignon Loh (Chair)
Wednesday, July 26, 2017
7:30 a.m. – 1:00 p.m.,
4:00 p.m. – 6:00 p.m.
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
Conference Registration
BREAKFAST
Conference Registration
Leukemia/Lymphoma Genomics
and Genetics
The Genomics of Childhood ALL
Charles Mullighan
Epigenetic Control of Blood
Malignancies
Scott Armstrong
The Molecular Origins of
Lymphoma
27 January 2017
Charles Mullighan (Chair)
Ricardo Dalla-Favera
New Insights Into the Pathogenesis
of AML
10:00 a.m. – 10:15 a.m.
12:00 p.m. – 12:30 p.m.
12:30 p.m. – 2:00 p.m.
Ross Levine
(2 short talks will be added from
posters)
FASEB Sponsored Coffee Break
Business Meeting
LUNCH
Career Development Session
1:00 p.m. – 2:30 p.m.
1:00 p.m. – 4:00 p.m.
4:00 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:00 p.m.
RO1 and Foundation Funding for
New Investigators
Free time
Poster Session
Conference Registration
DINNER
Stem Cells and the Initiation of
Blood Malignancies
Representative from the Evans
Foundation and Iannis Aifantis with
Adolfo Ferrando
Monica Guzman (Chair)
Detection of Initiating Mutations in
Pre-leukemic Stem Cells
Ravi Majeti
Cancer Clonal Evolution and
Response to Targeted Therapies
Olivier Elemento
Novel Drug Options in Targeting
Leukemia Stem Cells
Monica Guzman
Multiple Myeloma Epigenetics
Johnathan Licht
Thursday, July 27, 2017
7:30 a.m. – 1:00 p.m.,
4:00 p.m. – 6:00 p.m.
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
27 January 2017
Conference Registration
BREAKFAST
Conference Registration
Tumor Microenvironment
Emmanuelle Passegue (Chair)
The Effects of Microenvironment in
Myeloid Neoplasms
Emmanuelle Passegue
Targeting the Multiple Myeloma
Microenvironment
Irene Ghobrial
Stem Cell Niches in the Bone
Marrow
Paul Frenette
Dynamic Imaging of Bone Marrow
Niches in Acute Leukemia
Cristina Lo Celso
10:00 a.m. – 10:15 a.m.
11:30 a.m. – 12:00 p.m.
12:00 p.m. – 1:00 p.m.
FASEB Sponsored Coffee Break
Business Meeting
LUNCH
1:00 p.m. – 2:30 p.m.
Meet the Experts Session
Finding a Job in Industry
Poster Session
4:00 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:00 p.m.
DINNER
Tumor Immunotherapy and Gene
Editing Approaches in Blood
Malignancies
Silvia Buonamici
Andrei Thomas-Tikhonenko (Chair)
CAR T Cells and their Therapy
Promise for Blood Cancers
Michel Sadelain
Mechanisms of Acquired Resistance
to Targeted Immunotherapy
Andrei Thomas-Tikhonenko
Recent Updates of Chimeric Antigen
Receptor Clinical Trials
Marcela Maus
Designing Targeted CRISPRi Screens
Cathy Wu
Friday, July 28, 2017
7:30 a.m. – 12:00 p.m.
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 11:30 a.m.
Conference Registration
BREAKFAST
Conference Registration
Epigenetics of Hematologic
Malignancies
Kathrin Bernt (Chair)
DNMT3a, DNA Methylation and the Peggy Goodell
Control of the Leukemia Epigenome
3D Chromosomal Structure and
Transformation of Blood Cell Stem
Cells
Jane Skok
Understanding DOT1L Function in
AML
Kathrin Bernt
Silvia Buonamici
10:00 a.m. – 10:15 a.m.
Regulation of Splicing in Myeloid
Leukemia
FASEB Sponsored Coffee Break
11:30 a.m. – 12:30 p.m.
Closing Keynote Speaker
27 January 2017
12:30 p.m.
Lymphoma Epigenetic Therapies
LUNCH to Go
and DEPARTURES
Ari Melnick
END OF CONFERENCE
For additional information contact:
FASEB Science Research Conferences
9650 Rockville Pike
Bethesda, MD 20814
www.faseb.org/src
27 January 2017