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JUDITH M. WILKINSON LESLIE S. TREAS KAREN BARNETT MABLE H. SMITH FUNDAMENTALS OF NURSING Chapter 23: Promoting Asepsis & Preventing Infection Infection When microorganisms capable of producing disease invade the body Copyright © 2016 F.A. Davis Company The Spread of Infection: Six Links Infectious agents • Pathogens • Normal flora that become pathogenic Reservoir • Where pathogens live and multiply • May be living • Humans, animals, insects • May be nonliving • Food, floors, equipment, contaminated water Copyright © 2016 F.A. Davis Company The Spread of Infection: Six Links (cont’d) Portal of exit Mode of transmission • Via • Contact – Bodily fluids – Coughing, sneezing, diarrhea – Seeping wounds – Tubes, IV lines – Direct—touching, kissing, sexual contact – Indirect—contact with a fomite • Droplet: cough, sneeze • Airborne: via air conditioning, sweeping Copyright © 2016 F.A. Davis Company The Spread of Infection: Six Links (cont’d) Portal of entry • Eye, nares, mouth, vagina, cuts, scrapes • Wounds, surgical sites, IV or drainage tube sites • Bite from a vector Susceptible host • Person with inadequate defense • Four determining factors • Virulence • Organism’s ability to survive in the host’s environment • Number of organisms • Host’s defenses Copyright © 2016 F.A. Davis Company Stages of Infection • Incubation: from time of infection until manifestation of symptoms; can infect others • Prodromal: appearance of vague symptoms; not all diseases have this stage • Illness: signs and symptoms present • Decline: number of pathogens decline • Convalescence: tissue repair, return to health Copyright © 2016 F.A. Davis Company Classification of Infections By location • Local – Occurs in a limited region in the body (e.g., urinary tract infection) • Systemic – Spread via blood or lymph – Affects many regions (e.g., septicemia) Copyright © 2016 F.A. Davis Company Classification of Infections by Duration Acute: rapid onset of short duration (e.g., common cold) Chronic: slow development, long duration (e.g., osteomyelitis) Latent: infection present with no discernible symptoms (e.g., HIV/AIDS) Copyright © 2016 F.A. Davis Company Healthcare-Related Infection An infection acquired as a result of healthcare • Cost to the healthcare system = $4.5 billion/year • Leading cause of death • Preventable with use of aseptic principles/techniques Exogenous healthcare-related infection: Pathogen acquired from healthcare environment Endogenous healthcare-related infection: Normal flora multiply and cause infection as a result of treatment Copyright © 2016 F.A. Davis Company Lines of Defense Against Infection Primary defenses • Anatomical features, limit pathogen entry – Intact skin – Mucous membranes – Tears – Normal flora in gastrointestinal (GI) tract – Normal flora in urinary tract Copyright © 2016 F.A. Davis Company Lines of Defense Against Infection (cont’d) Secondary defenses • Biochemical processes activated by chemicals released by pathogens • Phagocytosis • Complement cascade • Inflammation • Fever Copyright © 2016 F.A. Davis Company Lines of Defense Against Infection (cont’d) Tertiary defenses • Humoral immunity • B-cell production of antibodies in response to an antigen • Cell-mediated immunity • Direct destruction of infected cells by T cells Copyright © 2016 F.A. Davis Company Tertiary Defenses: Humoral; Cell Mediated Copyright © 2016 F.A. Davis Company Factors That Increase Infection Risk • • • • • • • Developmental stage Breaks in the skin Illness/injury, chronic disease Smoking, substance abuse Multiple sex partners Medications that inhibit/decrease immune response Nursing/medical procedures Copyright © 2016 F.A. Davis Company Factors That Support Host Defenses • Adequate nutrition • To manufacture cells of the immune system • Balanced hygiene • Sufficient to decrease skin bacterial count • Not overzealous; causes skin cracking • Rest/exercise • Reducing stress • Immunization Copyright © 2016 F.A. Davis Company Preventing Infection: Implementing Medical Asepsis Medical asepsis • “A state of cleanliness that decreases the potential for the spread of infections” • Promoted through • Maintaining a clean environment • Maintaining clean hands • Following guidelines from the Centers for Disease Control and Prevention (CDC) Copyright © 2016 F.A. Davis Company Maintaining a Clean Environment • Clean spills and dirty surfaces promptly. • Remove pathogens through chemical means (disinfect). • Remove clutter. • Consider supplies brought to the client room as contaminated. • Consider items from the client’s home as contaminated. Copyright © 2016 F.A. Davis Company Wash Your Hands • When you arrive in the unit • When you leave the unit • Before and after restroom use • Before and after client contact • Before and after contact with client belongings Copyright © 2016 F.A. Davis Company Wash Your Hands (cont’d) • Before gloving • After glove removal • Before and after touching your face • Before and after eating • After touching a contaminated article • When you see visible dirt on your hands Copyright © 2016 F.A. Davis Company Handwashing Guidelines • Wash for at least 15 sec in nonsurgical setting; 2 to 6 min in surgical setting. • Remove jewelry and clean beneath fingernails. • Use a bactericidal solution or use water if hands are visibly soiled. – – – – – Use warm water, not hot. Apply soap to wet hands. Use friction. Rinse soap. Towel or hand dry. Copyright © 2016 F.A. Davis Company Implementing CDC Guidelines Standard precautions • Protects healthcare workers from exposure • Decreases transmission of pathogens • Protects clients from pathogens carried by healthcare workers Copyright © 2016 F.A. Davis Company Transmission-Based Precautions Contact precautions Pathogen is spread by direct contact • Sources of infection: draining wounds, secretions, supplies • Precautions include – – – – Possible private room Clean gown and glove use Disposal of contaminated items in room Double-bag linen and mark Copyright © 2016 F.A. Davis Company Transmission-Based Precautions (cont’d) Droplet precautions Pathogen is spread via moist droplets • Coughing, sneezing, touching contaminated objects • Precautions include – Same as those for contact – Addition of mask and eye protection within 3 ft of client Copyright © 2016 F.A. Davis Company Transmission-Based Precautions (cont’d) Airborne precautions Pathogen is spread via air currents • Transmission via ventilation systems, shaking sheets, sweeping • Precautions include – Same as those for contact, with addition of special room, special mask, and mask for patient when transported Copyright © 2016 F.A. Davis Company Protective Isolation “Protective environment” • Protects the client from organisms • Used in special situations with immune-compromised client population • Precautions include • Room with special ventilation and air filters; no carpeting; daily wet-dusting • Avoiding standing water in the room (e.g., humidifier) • Nurse not assigned to other clients with active infection • Standard and transmission-based precautions, plus mask and other personal protective equipment (PPE) (to protect patient) Copyright © 2016 F.A. Davis Company Implementing Surgical Asepsis Includes • Creation of a sterile environment • Use of sterile equipment/supplies • Sterilization of reusable supplies • Surgical hand scrub • Surgical attire • Sterile gloves • Sterile field • Use of sterile technique Copyright © 2016 F.A. Davis Company Think Like a Nurse You are working as a nurse on a medical-surgical unit. What roles might you play in the chain of infection? That is, what “links” might you be? Copyright © 2016 F.A. Davis Company