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Inside Cancer: How genes influence cancer development Course Outline – September 2016 Activity 1 Week 1 – What is cancer? Week 2 – The genetics of cancer Week 3 – The roads to cancer (part 1) Week 4 – The roads to cancer (part 2) Week 5 - Understanding and treating cancer Week 6 – Researching cancer © 2016 University of Bath Activity 2 Activity 3 What is cancer? Why do you get cancer? Survival of the nastiest – understanding cell division What are genes? Why do DNA mutations matter? Epigenetics Behaviour of rogue cells Chemical signals Death-defying cancer cells Angiogenesis Metastasis Other roads to cancer Diagnostics and treatment planning Conventional treatments Challenges of conventional therapy Models used in the laboratory Drug Discovery Where are we going?