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BIOLOGY 340
Principles of Genetics
Fall 2014
Instructor: M. A. Romano
Office Hrs: 3-3:50 pm, Mon: 1-2:50 pm, Tue;
Office: Room 240
10-11:50 am, Wed; or by appointment.
Lecture: Room 378
Phone: 298-1374, Email: [email protected]
Web page: http://www.wiu.edu/cas/biological_sciences/faculty/romano_m.php
Objective
Genetics is the study of inherited variation and the mechanisms for variation. You should be able to understand and predict patterns of
inheritance, understand the basic mechanisms of DNA function and the manipulation of DNA. Finally since genes are the basic units
for evolutionary changes at the population level, you should have a grasp of the fundamental evolutionary principles after completing
this course.
TENTATIVE LECTURE SYLLABUS
Week and Date
1
Aug
2
Sep
3
4
5
6
Oct
7
8
9
10
11
Nov
Chapter in Text*
Lecture Topic
25
27
29
1
3
5
8
10
M
W
F
M
W
F
M
W
12
F
15
M
17
19
22
24
25
26
29
1
3
6
8
10
13
15
17
20
W
F
M
W
TH
F
M
W
F
M
W
F
M
W
F
M
22
23
24
27
29
31
3
W
TH
F
M
W
F
M
Intro., Review Mitosis
Review Mitosis cont., Meiosis
Review Meiosis cont.
LABOR DAY – NO CLASSES
Mendelian Genetics cont./Significance of Meiosis
Multiple alleles, Gene Interaction, Complementation
Multiple alleles, Gene Interaction, Complementation cont.
Sex Chromosomes and Sex Determination
Sex Linkage, Phenotypic expression
Sex Chromosomes and Sex Determination
Sex Linkage, Phenotypic expression cont.
Chromosomal mutation (Chromosome Structure and DNA
sequence organization)
Chromosome mutation cont.
Linkage and Mapping in Eukaryotes
Linkage and Mapping Continued
REQUIRED REVIEW SESSION FOR EXAM
HOUR EXAM I - 20% of Grade
Mapping in prokaryotes and viruses
Mapping in prokaryotes and viruses cont.
DNA Structure
DNA Replication
Chromosome Structure and DNA sequence organization
DNA and the Genetic Code
FALL BREAK – NO CLASSES
DNA and the Genetic Code cont.
RNA and Transcription
RNA and Transcription cont.
Translation and Proteins
Mutation, Repair and Transposable Elements
REQUIRED REVIEW SESSION FOR EXAM
HOUR EXAM II - 20% of Grade
Mutation, Repair and Transposable Elements cont.
Gene Expression
Gene Expression cont.
Recombinant DNA Technology
Genomics
1,2
2
2
3,2
4
4
4,5
4,5
6
6
7
7
8
8
9
10
11
12
12
12
12
13
14
14
15
15
17
18
5
7
10
12
13
14
17
19
21
12
13
14
15
16
17
Dec
W
F
M
W
TH
F
M
W
F
Polygenic Inheritance (Quantitative genetics)
Polygenic Inheritance (Quantitative genetics) cont.
Population Genetics
REQUIRED REVIEW SESSION FOR EXAM
HOUR EXAM III - 20% of Grade
Population Genetics Cont.
Population Genetics Cont.
Genetics and Evolution
Genetics and Evolution cont.
24-28
1
M
No Classes - Thanksgiving Break
Genetics and Evolution cont.
3
5
8
10
12
15
W
F
M
W
F
M
Conservation Genetics
Conservation Genetics cont.
Conservation Genetics cont.
Catch Up
Catch Up
FINAL EXAM - 3:00 pm, Room 378
21
21
22
22
22
22
22,
Supplements
22,
Supplements
23
23
23
*Klug, W. S. et al. 2013. Essentials of Genetics, 8th Edition. Prentice Hall, Inc., Upper Saddle River, New
Jersey. 531 pp.
COURSE PREREQUISITES
BIOL 330; ENG 280
COURSE REQUIREMENTS AND GRADING
Points
200
150
200
550
Hour exams (3, the 2 highest exams count)
Final Exam
Laboratory
Total:
99.0% - 100%+
91% - 98.99%
90% - 90.99%
89% - 89.99%
81% - 88.99%
80% - 80.99%
79% - 79.99%
A
A
AB+
B
BC+
GRADING SCALE
71% - 78.99%
70% - 70.99%
69% - 69.99%
61% - 68.99%
60% - 60.99%
<60%
C
CD+
D
DF
EXTRA CREDIT
There are extra credit assignments which will be given during portions of the course. The optional book by the
American National Academy of Sciences forms the basis of an extra credit quiz attached to the third exam worth 25
points. Additionally in an attempt to cultivate your ability to begin teaching yourselves, a given chapter or portions
of a given chapter will form 15 points extra credit on each exam.
WRITING IN THE DISCIPLINE (WID)
This course has been designated to meet the Writing Instruction in the Disciplines (WID) graduation
requirement. WID courses provide instruction in the processes and formats for the writing content and style needed
to be an effective professional in a student’s chosen field. The lab reports, particularly the first one, will represent
training in technical writing in biology.
EXAMS
Exams will be scheduled on selected Thursday evenings during the course of the semester (September 19th,
October 17th, and November 7th). A memo will be distributed in class that must be signed by the student indicating
she/he is aware of the situation and will make the necessary adjustments in their schedules to meet the assigned
examination period. All labs will be cancelled during the week of exams and students with extenuating
circumstances and cannot possibly make the evening exam time will agree to take the exam earlier in the day at a
time specified by Dr. Romano.
MAKEUPS
I do give makeups for extenuating circumstances and I will be the arbiter of whether a given circumstance is
extenuating. However, my makeups are all essay and very few students have successfully passed my makeups in
core courses.
ATTENDANCE POLICY
I do not take attendance in lecture in this course; however, it is not a good idea to skip class. Students who skip
class rarely pass.
Lab is mandatory.
Two unexcused absences = automatic F
Four missed labs for any reason = automatic F
SPECIAL NEEDS
In accordance with University policy and the Americans with Disabilities Act (ADA), academic
accommodations may be made for any student who notifies the instructor of the need for an accommodation. For
the instructor to provide the proper accommodation(s), you must obtain documentation of the need for an
accommodation through the Disability Resource Center and provide it to the instructor. It is imperative that you
take the initiative to bring such needs to the instructor's attention, as he/she is not legally permitted to inquire about
such particular needs of students. Students who may require special assistance in emergency evacuations (i.e. fire,
tornado, etc.) should contact the instructor as to the most appropriate procedures to follow in such an emergency.
Contact the Disability Resource Center at 298-2512 for additional information and services.
STATEMENT ON CHEATING AND PLAGIARISM
Cheating will not be tolerated in this course. I do allow students to work on the data for lab reports if they so
choose. However, each student must turn in an independently written lab report. Should a student copy another
student's exam, she/he will receive a zero and procedures outlined in the academic dishonesty section of WIU
webpage will be followed. If a student is caught collaborating with another student on a midterm or final, both
students will receive zeros and procedures outlined in the academic dishonesty section of the WIU webpage will be
followed.
I consider plagiarism more serious than simple cheating on exams.
Definition of Plagiarism
Several years back faculty of the Department of Biological Sciences defined plagiarism as expressed by V. E.
McMillan in Writing Papers in the Biological Sciences (Bedford/St.Martin's Press, New York, pg 16):
"Plagiarism is the theft of someone else's words, work, or ideas. It includes such acts as (1) turning in a friend's
paper and saying it is yours; (2) using another person's data or ideas without acknowledgement; (3) copying an
author's exact words and putting them in your paper without quotation marks; and (4) using wording that is very
similar to that of the original source but passing it off as entirely your own even while acknowledging the source."
This includes information in textbooks or laboratory manuals, honors and masters theses, all writing assignments,
and images. Along with my TA, we attempt to monitor student writing assignments (essay exams, papers,
laboratory reports, and other writing assignments or exercises) for incidence of plagiarism. If plagiarism is found, I
(or we) will discuss the situation with the student and indicate to the student the penalty for this academic
dishonesty. Potential penalties include those cited in the academic dishonesty section of the WIU web page,
http://www.wiu.edu/policies/acintegrity.php. An Academic Dishonesty Report will be filled out and forwarded
to CAGAS and the Chair of Biological Sciences. Should a student choose to appeal the penalty, the process
outlined in Section IV of the University Academic Integrity Policy entitled, ‘Undergraduate and
Graduate Procedure, Step Two: Appeals’ will be followed.
ADDITIONAL STUDENT RESOURCES
It is the student’s responsibility to be familiar with the information (including required forms, definitions,
and time lines) contained in the following university web sites. Each student should access these web sites and
carefully read the information they contain, your instructors will hold you responsible for knowing this information.
If you have questions about any of the information contained in the web sites, ask your instructor:
Students Rights and Responsibilities: http://www.wiu.edu/provost/students.php
University Final Exam Policy: http://www.wiu.edu/policies/finexam.php
Academic Dishonesty Policy: http://www.wiu.edu/policies/acintegrity.php
Grade Appeal Policy: http://www.wiu.edu/policies/gradeapp.php
Western Online: https://westernonline.wiu.edu/d2l/home
Disability Resource Center: http://www.wiu.edu/student_services/disability_resource_center/
Complete Policy site: http://www.wiu.edu/policies/