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Executive Summary FC1109 ‘Studies on Fish Disease and Shellfish Hygiene’ This project addressed work in the area of fish disease and shellfish hygiene through the provision of sandwich students to undertake specific projects in these areas. Students were seconded to the Centre for Environment, Fisheries and Aquaculture Science (CEFAS) at Weymouth to work on projects related to research commissioned by the Fisheries Customer. The project supported three students in the first year and studies focused on molecular biology approaches to detection of Viral Haemorrhagic Septicaemia (VHS) virus infecting wild fish species, cell structure assays for detection of paralytic shellfish poison (PSP) toxins, and development and characterisation of methods for the detection of enteric viruses in oysters associated with outbreaks of infectious disease. In the second year the project supported three students. Further studies were performed on Viral Haemorrhagic Septicaemia and Spring Viraenia of Carp in particular examining their distribution in both marine and fresh water fish; on investigation into alternative indicators of sewage pollution in shellfish such as FRNA bacteriophage, in particular examining their elimination during shellfish depuration; and on the detection and characterisation of human enteric viruses isolated from shellfish associated with a large outbreak of viral gastroenteritis. In the third year the project supported two students in the shellfish hygiene area of work. Studies were performed on the methods for processing shellfish to improve recovery of human enteric viruses and on the development of methods for characterisation of Norwalk-like virus, and other enteric viruses, isolated from shellfish through PCR amplification and genome sequencing. Full abstracts of these studies are given in the Scientific Report Section and full yearly reports have been supplied at the end of each year of these studies . Further copies of the annual reports can supplied by CEFAS Weymouth if required. The project was very successful and all students performed valuable work helping to underpin ongoing lines of research at CEFAS Weymouth. The additional support provided by the students was found to be vary valuable by all student supervisors and helped to significantly develop and extend key areas of CEFAS research. All students reported enjoying their time at Weymouth and several have since returned as CEFAS employees. The student programme therefore has been seen to have had significant benefits for both CEFAS, the University and the Fisheries customer in the development of the R&D programme. Staff at CEFAS greatly appreciate the support of the Fisheries Customer and of the Chief Scientist Group in enabling this cost-effective programme of student secondment to be developed. A further five-year programme of student secondment has now been agreed carrying on the valuable support to the fisheries research carried out at CEFAS Weymouth which this project has provided.