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Vertigo Paul Chatrath Consultant ENT/Head & Neck Surgeon Charing Cross Hospital (Imperial Healthcare NHS Trust) Honorary Senior Lecturer Anglia Ruskin University, Chelmsford Visiting Professor of Rhinology Canterbury Christ Church University, Kent 6th September 2016 Objectives Dizziness / vertigo in general ENT causes for vertigo Meniere’s BPPV Labyrinthitis Other ENT causes of dizziness ‘red flags’ Case - Dizziness Please see this 40 year old female suffering with short lived episodes of vertigo Occurring almost daily Occurs whenever moves head in any direction Clinical approach Vertigo vs dizziness Vertigo Rotatory Suggests a peripheral vestibular or cerebellar problem Dizziness / lightheadedness Non-specific ‘whoozy’ ‘ lightheaded’ ‘unsteady’ ‘drunken’ Suggests non-vestibular pathology Types of Dizziness Rotation (Spinning) Unsteadiness (Imbalance) Light headedness (faint feeling) If the patient has ever lost consciousness: it is not ENT! Vertigo - causes Vestibular Viral labyrinthitis BPPV Meniere’s disease Acute Otitis Media Trauma Cholesteatoma Drug induced Postsurgical Central Migraine Vertebrobasilar ischaemia MS Tumours Cerebellopontine angle Acoustic neuroma Brainstem CVA Psychogenic Non-specific dizziness: Causes Cardiovascular Arrhythmias Reduced cardiac output Carotid artery stenosis Arteriosclerosis Hypotension (postural) Peripheral neuropathy Proprioception Arthritis (cervical and other) DM Hypothyroidism Hypercholesterolaemia Anaemia B1, B6, B12 Genetic - Refsum’s disease Toxins Leprosy, TB, syphilis Vitamin deficiencies Metabolic DM Renal or hepatic failure Alcohol Vasculitis Infections Lead, metronizadole Psychogenic Vertigo: Duration is key Brief (<1min) - specific head movement - any head movement Hours BPPV Psychogenic BPPV Psychogenic Meniere’s Migraine Days (>24hrs) Viral labyrinthitis Meniere’s Migraine - classic triad - classic headache Nystagmus Movement of the eyes: Rhythmic Oscillating Synchronous Involuntary Two phases Slow phase (pathological) Fast phase (corrective) Direction described in terms of fast phase Nystagmus Normal labyrinths Abnormal Right Labyrinth R L Eyes central L X Slow drift to right Rapid corrective flick to left = Left nystagmus Vertigo: Compensation Vestibular phenomenon Steady accommodation to the effects of vertigo Gradual resolution of symptoms over time Typically occurs 6-12 weeks after acute insult Mechanisms Habituation Reduced output good side Increased output affected side Sensory substitution Increased reliance on eyes and musculoskeletal system Vertigo: Compensation Impaired compensation due to: Poor visual acuity Musculoskeletal problems Reduced peripheral sensory input Ongoing vestibular pathology Medication (prolonged stemetil) Rehabilitation: General fitness Physical programs Vision, walking stick Cawthorne-Cooksey Psychological support Specific exercises Eg. Brandt-Daroff exercises for BPPV Vertigo: Vestibular v Central Vestibular Central Type of dizziness Vertigo Vertigo / Dizzy Effect of head movement Worse Equivocal Tinnitus/hearing loss May be present Absent Compensation Occurs Does not occur Nystagmus Horizontal + unilateral + away from affected ear Horizontal or vertical + bilateral Vestibular rehabilitation: Cawthorne - Cooksey Head movements Balance tasks Coordination of eyes with head Total body movements Eyes open & closed Noisy environments Causes early exacerbation of vertigo Caution: Prochlorperazine Powerful vestibular sedative Suppresses acute vertiginous symptoms BUT Also suppresses natural compensatory response LT use:‘non-specific dizziness’persists Psychogenic Type of dizziness: any (nonspecific or vertigo) Frequency: constant Duration: Typically brief <1min Trigger: Stress, anxiety, crowds Associated features: palpitations, sweating, tremor Examination: Normal Labyrinthitis History Vertigo >24hrs Vomiting Constitutional symptoms Usually following URTI Treatment Examination Nystagmus Fast phase away from affected ear Pyrexia Bed rest Vestibular sedatives Fluids Cawthorne-Cooksey vestibular rehabilitation exercises Rule of threes - 3 days: v bad, 3 weeks, a lot better, 3 months resolved Meniere’s Disease Key features: Vertigo Tinnitus/hearing loss Before/during/after vertigo Other symptoms Hours Pressure feeling Nausea Natural history One episode Episodic Increasing frequency Salt restriction Diuretics - thiazides Vasodilators Betahistine, cinnarizine Evidence – no RCTs Cinnarizine > placebo Diuretics = placebo Serc of marginal benefit Salt restriction of marginal benefit Intratympanic therapy: Steroids or Gentamicin BPPV: Benign Paroxysmal Positional Vertigo Calcific debris in semicircular canals Vertigo Brief (<1min) On head turn in a particular direction Typically self-limiting Primary Secondary Trauma (HI) Prolonged bed rest Otological condition (up to 70%) Posterior SCC In plane on lying in bed Hallpike’s test Nystagmus on lying back to one side BPPV - Epley Epley, 1992 BPPV - Brandt & Daroff Brandt & Daroff, 1980 Migraine Clinical features Lifestyle change Family history Motion intolerance Vertigo occurs with classical headache either before or after ENT/vestibular examination usually NAD Exercise, diet, avoidance of stimulants Medication: Abortive therapy eg. Sumatriptan Prophylactic therapy eg. B blockers Other ENT conditions causing dizziness Ear: Nose/Sinus Malignant OE Otitis media Cholesteatoma Sinusitis Thyroid disturbance Dizziness/Vertigo: Indications for Urgent Referral Vertigo Intense Disabling Unremitting Nystagmus Sudden SNHL Features to suggest malignant pathology Elderly with granulation in ear canal VIIn palsy Post-traumatic TM perforation + vertigo Conclusion Must define the dizziness / vertigo Rotatory or not Frequency Triggers History is the most important factor Duration Vertigo BPPV (cervical / psychogenic) Meniere’s (Migraine) Labyrinthitis (Drug / multifactorial) ENT causes for vertigo When to refer urgently Case Please see this 40 year old female suffering with short lived episodes of vertigo Occurring almost daily Occurs whenever moves head in any direction Vertigo Paul Chatrath Consultant ENT/Head & Neck Surgeon Charing Cross Hospital (Imperial Healthcare NHS Trust) Honorary Senior Lecturer Anglia Ruskin University, Chelmsford Visiting Professor of Rhinology Canterbury Christ Church University, Kent [email protected] 6th September 2016