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Pathogen Webquest Go to the following websites and watch the videos/animations the answer the questions ON A SEPARATE SHEET OF PAPER. Hepatitis C Infection http://www.healthcentral.com/animation/408/33.html (watch the video) 1. 2. 3. 4. 5. What is hepatitis C? How is Hepatitis C passed from person to person? How does Hepatitis spread throughout the body? What organ does it affect? What are the symptoms? Bacterial Infections http://www.microbelibrary.org/microbelibrary/files/ccImages/Articleimages/tterry/anim/phago053.html WATCH – “Normal phagocytosis by a macrophage” 6. What is phagocytosis? How does it begin? 7. How big is a macrophage? A bacterium? 8. Why do lysosomes need acid pH? 9. What is an “oxygen burst”? 10. What happens to the bacterium after it has been fused & broken down by the lysosome? Click “Index” to return to the main menu WATCH – “Yersinia pestis infects a macrophage” 11. What is Yersinia pestis? 12. How does the Type III secretory apparatus of Yersinia pestis work? 13. What do the 4 different “YOP” proteins do? 14. What eventually happens to a macrophage that is invaded by YOPs? 15. How fast do plague bacteria grow? Click “Index” to return to the main menu WATCH – “Mycobacterium tuberculosis infects a macrophage” 16. What is Mycobacterium tuberculosis? 17. How common is infection with TB? 18. What do the virulence proteins of TB do to the macrophage? 19. “Watch bacteria go latent” - What happens when the bacteria becomes latent? 20. “see what happens when the immune system fails” & “watch host cell die” – What happens to the macrophage? Fungal infections http://www.saber.ula.ve/micosis/parser.php?XML=contenido/capitulo1/contenidocapitulo.xml&XSL=xsl/in dicefigurascapitulo.xsl&IDIOMA=en Click on at least 3 of the pictures and write down the name of the fungus that causes it, what the infection looks, and any other information given. (Questions 21-23) Parasite Infections (GRAPHIC – remember these are REAL people with these infections) http://www.curezone.com/image_gallery/parasites/ Scan through some of the photos of different worm infections and answer the following: 24. List 4-5 different worms that infect humans and as well as a short explanation of what they do and the body system that they infect? Protist Infection http://www.sumanasinc.com/scienceinfocus/sif_malaria.html “Click to view animation” – watch the narrated or step through animation. 25. 26. 27. 28. 29. 30. 31. What is Plasmodium falciparum? What disease does it cause and how is it passed to humans? What organ does the parasite travel to once in the human body? What does it do there? Where do the merozoites go now? What do they do there? What are gametocytes? What do they allow the parasite to do? How does the parasite return to a mosquito? What happens once it is there? Return to the home page – what are the symptoms of this disease? FUN & GAMES http://nobelprize.org/educational_games/medicine/malaria/ Play the Mosquito AND/OR Parasite game http://www.blood.co.uk/pages/games.html Play Bacteria Bash!