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 In the 1880’s, psychiatrist Sigmund Freud wrote and prescribed cocaine as a treatment for many ailments such as depression & addiction to alcohol and opiates. Pure cocaine was first isolated from the leaves of the coca bush in 1860.  Contained in small amounts in the leaves of erythroxylum (coca) bush  Researchers soon discovered that cocaine numbs whatever tissue it touches.  This lead to it’s use as a local anesthetic.  Coca leaves grow on the slopes of the Andes Mountains in South America.  For at least 4,500 years, people in Peru & Bolivia have chewed the coca leaves to lessen hunger & fatigue.  Most of the world’s supply of coca is grown & refined into cocaine in Colombia.  http://www.youtube.com/watch?v=U_b ZZt1zs60&feature=related  http://www.youtube.com/watch?v=0vn Nl-cCYJA&feature=related  http://www.youtube.com/watch?v=E0H KSYEPwV8&feature=related  Stimulant Snorted Smoked Injected Faster the absorption, the shorter the high……  Snorting may last 15 to 30 minutes   Smoking may last 5 to 10 minutes  Injection – 3 minutes  Once the drug leaves the brain, users experience a “coke crash” that triggers depression, irritability & fatigue. Heart - Cocaine is bad for the heart. Cocaine increases heart rate and blood pressure while constricting the arteries supplying blood to the heart.  Brain - Cocaine can constrict blood vessels in the brain, causing strokes. This can happen even in young people without other risk factors for strokes. Cocaine causes seizures and can lead to bizarre or violent behavior.   Lungs and respiratory system. Snorting cocaine damages the nose and sinuses. Regular use can cause nasal perforation. Smoking crack cocaine irritates the lungs and, in some people, causes permanent lung damage.  Sexual function. Although cocaine has a reputation as an aphrodisiac, it actually may make you less able to finish what you start. Chronic cocaine use can impair sexual function in men and women. In men, cocaine can cause delayed or impaired ejaculation. Psychologically  Not physiologically although withdrawal or “coming down off drug” is extremely difficult on the body  http://www.youtube.com/watch?v=qAD B1JdkYp0  http://www.youtube.com/watch?v=i2Pw CuynrhM&feature=related  Dilated pupils  Increased body temperature, Blood pressure & heart rate  Insomnia  Loss of appetite  Increased energy  Reduced fatigue  Mental clarity  Talkativeness  Paranoia  Depression  Ulcers in the membranes of the nose  Changes in the chemistry of the brain  Dulled senses of taste & smell  Weight loss, poor health & sexual dysfunction  Loss of social & financial supports  Holes in bony separation between nostrils in nose  About 14% of U.S. adults have tried cocaine.  Young men aged 18 to 25 are the biggest cocaine users, with 8% using it in the previous 12 months.  One in 40 adults has used it in the past year.