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MESA COLLEGE, SAN DIEGO SCHOOL OF MATHEMATICS & NATURAL SCIENCES General Biology Lecture (BIOL 107); Instructor: Elmar Schmid, Ph.D. TTA AK KE EH HO OM ME EQ QU UIIZZ ##55 Answer the following questions and mark it on a Scantron 882 answer sheet. All questions must be answered by the student without help by class mates, friends or other human beings. Make sure that you read the following statement below carefully and sign it if you satisfy the guidelines outlined in this statement. This signed take home exercise sheet (= page 1 of this document) must be turned in together with your completed Scantron card in order to receive full credit for this assignment. This assignment is due at the first class meeting the following week. I HAVE ANSWERED THE QUESTIONS IN THIS EXERCISE ON MY OWN. I DID NOT CONSULT OTHERS OR IN ANY CONDUCT IN ANY ACTIVITITES THAT COULD BE CONSTRUED AS CHEATING IN THIS ASSIGNMENT. I DID NOT MAKE ANY COPIES OF THIS ASSIGNMENT. _________________________________ (PRINT YOUR NAME) ________________________________ (YOUR SIGNATURE) Q. 1: An organism with two different alleles for a single trait is said to be A) homozygous B) heterozygous C) genotypic similar D) hemizygous E) inbred Q. 2: You carefully following up the family history of a certain disorder. Your pedigree investigation reveals that one or two family members (male or female) of every other generation were affected by the fatal disorder. You conclude, that: A) the disorder is inherited in an autosomal recessive manner B) the disorder is inherited in an autosomal dominant manner C) the disorder is inherited in an X-linked fashion D) the disorder is inherited in an Y-linked fashion E) the disorder is contagious and runs in the family Q. 3: In guinea pigs, rough coat is dominant over smooth coat. In a cross between a heterozygous guinea pig and a rough-coated guinea pig, what would be the expected genotypic ratio of the offspring of this couple? A) all RR B) 75% Rr 25% RR C) 50% Rr 50% RR D) 25% Rr 75% RR E) all Rr Q. 4: A violet petal-colored orchid is crossed with another violet-colored orchid. You observe that 50% of the offspring have violet-colored petals on their flowers and 25% of the offspring show either red or blue flowers. You conclude that this observation is the expected outcome of ______ in genetics. A) blending B) co-dominance C) incomplete dominance D) Mendelian inheritance E) dihybrid cross 1 MESA COLLEGE, SAN DIEGO SCHOOL OF MATHEMATICS & NATURAL SCIENCES General Biology Lecture (BIOL 107); Instructor: Elmar Schmid, Ph.D. Q. 5: Since the behavior of chromosomes during meiosis accounts for the inheritance pattern of Mendel’s factors, which process during meiosis is responsible for Mendel’s observation of independent assortment of alleles? A) Interphase B) Metaphase I C) Anaphase I D) Metaphase II E) Anaphase II Q. 6: A pea plant which is heterozygous tall and has wrinkled seeds is crossed with a plant which is dwarf and is homozygous round-seeded. Tall and round are dominant traits. Which of the following would be the genotype of the F1 generational offspring? A) all TTRR B) 50% TTRR; 50% ttrr C) all TtRr D) 25% TTRR, 50% TtRr, 25% ttrr E) 50% TtRr, 50% ttRr Q. 7: Which of the following is an example of incomplete dominant inheritance in humans? A) sickle-cell disease B) familial hypercholesterolemia (fHC) C) cystic fibrosis D) albinism E) achondroplasia Q. 8: Which of the following statements about the heritable disorder familial Hypercholesterolemia (fHC) is/are correct? A) Only homozygous recessive individuals are affected B) It is caused by mutations of the gene coding for the LDL receptor C) It is caused by mutations of the gene coding for hemoglobin D) It is characterized by elevated cholesterol levels in the blood plasma E) both, b and d Q. 9: A mating between two drosophila flies, both heterozygous regarding two different alleles (= GgPp), turns out NOT to retrieve the expected Mendelian 9:3:3:1 pattern regarding the phenotypes in the next generation. Only about 4% of all offspring (instead of 18.7%) showed new phenotypes different to the P-generational flies. You conclude that the two alleles are located on the X chromosome and that the new phenotypes observed are due to independent assortment. A) True B) False Q. 10: What would be the expected phenotypes of children from a mating between a woman with blood type O and a heterozygous with blood type A? A) all O B) either A or B C) all A D) either A or O Q. 11: What is the (molecular) phenotype responsible for the different blood types in humans? A) the presence or absence of the Rhesus factor on red blood cells B) the presence or absence of certain phospholipids in the membrane of white blood cells C) the presence or absence of certain antigenic sugar residues on the surface of red blood cells D) the presence or absence of an additional cell type in the human blood E) the presence or absence of a harmless virus in the blood 2 MESA COLLEGE, SAN DIEGO SCHOOL OF MATHEMATICS & NATURAL SCIENCES General Biology Lecture (BIOL 107); Instructor: Elmar Schmid, Ph.D. Q. 12: In a cross between a heterozygous red-eyed female fruit fly and a white-eyed male fly, what percent of the male fly offspring will have white eyes? (Use a Punnett square to predict and to visualize the outcome of this X-linked cross!) A) 100% B) 75% C) 50% D) 25% E) 0% (none) Q. 13: An emergency unit arrives at the scene of a serious accident where a person is heavily injured and looses a lot of blood. To save the persons life the doctors have to give a blood transfusion to the injured person right at the spot. The injured person has blood type AB. Which of the following blood bags carrying the following blood types labels can they use? A) only blood type AB B) blood type AB, B, A, and O C) only blood type AB, B, and A D) only blood type O Q. 14: A woman is (unknowingly) heterozygous regarding the albinism allele. She marries a “non-albino” man whose father is an albino. What is the chance “p” that one of the couples’ children will be born as an albino? A) 0.1 B) 0.25 C) 0.5 D) 1.0 E) not a chance Q. 15: A heterozygous pink petal-colored snap dragon plant (PR, Pr) is crossed with a homozygous parental red snap dragon plant (genotype: PR PR ). What percentage of the snap dragon offspring will have red blossom color? (Use a Punnett square to find the answer!) A) 100% B) 75% C) 50% D) 25% E) 0% Q. 16: Which of the following is a/are X-linked inherited human disorder(s)? A) Duchenne-type muscular dystrophy B) hemophilia C) X-linked severe combined immunodeficiency (X-SCID) D) Multiple sclerosis E) all of the above, except d Q. 17: The inheritance patterns and distribution of phenotypes such as height and skin color in humans is a classical example of which kind of inheritance? A) polygenic inheritance B) dihybrid crossing C) X-linked inheritance D) co-dominance E) incomplete dominance Q. 18: What is the thickness of a linear packed chromatin fiber? A) 1nm B) 30nm C) 1400nm D) 1mm E) 1m Q. 19: The ____ core protein components of a nucleosome are called _______ . A) 2 … nucleotides B) 4 … tubulin C) 4 … histones D) 4 … histamines E) 8 … histones 3 MESA COLLEGE, SAN DIEGO SCHOOL OF MATHEMATICS & NATURAL SCIENCES General Biology Lecture (BIOL 107); Instructor: Elmar Schmid, Ph.D. Q. 20: The darker bands visible at metaphase chromosomes after staining are called __ bands. Today we know these bands correspond to the highly condensed _______ regions of chromosomal DNA. A) G … heterochromatin B) G … euchromatin C) F … heterochromatin D) F … euchromatin Q. 21: Which observation do molecular biologists describe as the “C-value paradox”? A) All biological organisms have the same amount of cytosines (C) in their chromosomal DNA B) All biological organisms have the same number of alleles but different chromosome numbers C) All biological organisms (no matter how complex) have the same total amount of chromosomal DNA D) The total amount of chromosomal DNA in different biological species does not correlate with their body complexity E) The carbon (= C) content of chromosomal DNA of different biological organisms is the same Bonus Q.: What is the (molecular) phenotype responsible for the different blood types in humans? A) the presence or absence of the Rhesus factor on red blood cells B) the presence or absence of certain phospholipids in the membrane of white blood cells C) the presence or absence of certain antigenic sugar residues on the surface of red blood cells D) the presence or absence of an additional cell type in the human blood E) the presence or absence of a harmless virus in the blood 4