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Sense of smell- olfaction
• Olfactory receptor neurons have olfactory
cilia which mix the mucus covering of
olfactory epithelium.
• Mucus covered to dissolve airborne liquid
molecules
• Located in most superior part of nasal
cavity-that’s why we must sniff to detect
delicate odors.
• 4,000 – 10,000
odor molecules
detected by humans
Anosmia
• Complete lack of smell
• Results in depression– worse than in patients
with other sensory losses
• Causes:
– Damage to frontal lobe
– Nasal congestion
– Viral infections
– Genetic disorder
Rats with Anosmia
• Blind rat can survive
• Rats with anosmia won’t mate or eat  die
Taste and Smell are related
• The receptors share several common
pathways in the brain
• Odor molecules give us 70-75% of overall taste
–  flavor
Sense of Taste-- Gustation
• Taste buds contain chemoreceptors called
gustatory cells with cilia that project into taste
pores bathed in saliva
• Most taste buds are found in between
papillae: elevated projections of differing
shapes
• Fungiform papillae- large, anterior 2/3
tongue, contain one or a few taste buds
• Circumvallate papillae- huge, transverse row
at back of tongue, thousands of buds
• Foliate papillae- red ridges of mucosa on
lateral edges of posterior tongue, 100 buds
• Filiform papillae- bumps with tiny projections,
scattered, experience food TEXTURE
Primary tastes
• Each receptor cell responds most effectively to
only 1 of the 5 “primary tastes”:
– Sweet
– Sour
– Salty
– Bitter
– Umami/savory– this taste is perceived when
proteins are cooked and release amino acids
• What else influences our perception of taste?
Taste and location on tongue
• Can we “map” the tongue?
Taste and location on tongue
• Current research shows that all tastes can be
detected in all areas of tongue– regional
differences may not really exist
• ALL 5 taste receptor cells are in every taste
bud
Taste Preferences
• Prenatal tastes exposed to fetus
– Fetus swallows 200-760 mL of amniotic fluid daily
• Taste forms at early stage of gestation
• Flavors from maternal diet reach amniotic
fluid
Importance of taste
• Taste is the only special sense with 3 different
cranial nerve routes (VII, IX, X– facial,
glossophayngeal, and vagus) to the brain–
indicates taste important to survival (why?)