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What is radiculopathy and how would it present differently from neuropathy?
McCance and Huether(2006)define radiculopathies as "disorders of roots of spinal nerves" (p.
597). Radiculopathy is understood to occur when the nerve root as it emerges from or enters
vertebral canals damaged by compression, inflammation, and stretched or torn nerves (McCance
& Huether, 2006).Most radiculopathies are said to arise from either compressive or
noncompressive mechanisms;Compressive mechanisms are cervical spondylosis and disc
herniation, noncompressive mechanisms include diabetes, infections, infiltrating neoplastic
disorders, demyelination, root avulsion, nerve root infarction (Robinson & Kothari, 2007).
McCance and Huether describe clinical manifestations of radiculopathies as follows;Depending
on the affected nerve roots the strength, tone, and muscle in the patient are affected.Tone and
deep tendon reflexes are decreased but since the involved muscles use two or more spinal roots
to function the reflexes are never absent.Sensory dysfunction also occurs as the ventral and
dorsal roots are affected. Pain is also most often localized. Symptoms may be manifested in an
asymetrical fashion. In radiculopathy the patient may have acute onset of symptoms with no
immediate identifiable trauma or stress (Starkweather, 2006).Radicular pain can occur with
movement, stretching of root, and in occurences that increase CSF; sensory loss occurs in a
radicular pattern and spasm of the surrounding muscles of the vertebral column (McCance &
Huether, 2006).
Neuropathiies as defined by McCance and Huether (2006)are "The axons travelling to and from
the brain stem and spinal cord neuronal cell bodies may be injured by a multitude of disease
processes" (p. 595). Neuropathy most often presents through a progressive manner. The
presentation is usually exhibited in by bilateral, symmetrical, and distal involvement (Cruse,
2006). Distal involvement is mostly present because neuropathies typically affect the related
axon length, thereby longer axons are affected first.
The major treatment for radiculopathy is geared towards treating the cause of injury (McCance &
Huether, 2006). This may include steroids, radiation, chemotherapy.
Cervical nerve root compression may be seen with MRI or CT, lumbar puncture with CSF
exam,and spinal films to name a few.
Neuropathy in particular peripheral neuropathy as exhibited by Mr. C can be investigated by a
Mnemonic that was found in an entry for the spinal Cord Injury Nursing Journal: "DANG THE
TARPIRS"
iabetes/drugs
Alcohol
Nutritional
Traumatic
Hereditary
Endocrine
Toxins(lead toxicity)
Amyloids/AIDS
Porphyria/Paraneoplastic/Psychiatric
Infectious
Renal (uremic neuropathy)Radiation
Sarcoidosis
McCance,K.L., Huether, S.E. Pathophysiology: The biologic
basis for disease in adults and children (5th ed.).
Philadelphia: Elsevier Mosby.
www.UpToDate.com Treatment of Cervical radiculotherapy & Overview of acquired peripheral
neuropathies in children.
Starkweather, A, (2006). Radiculopathy, myelopathy, and peripheral neuropathy: Can you detect
the difference?. American Association of Spinal Cord Injury Nurses.
http://www.unitedspinal.org/publications/nursing